keyword
https://read.qxmd.com/read/38518051/the-intervention-of-artificial-intelligence-to-improve-the-weaning-outcomes-of-patients-with-mechanical-ventilation-practical-applications-in-the-medical-intensive-care-unit-and-the-covid-19-intensive-care-unit-a-retrospective-study
#1
JOURNAL ARTICLE
Yang-Han Lin, Ting-Chia Chang, Chung-Feng Liu, Chih-Cheng Lai, Chin-Ming Chen, Willy Chou
Patients admitted to intensive care units (ICU) and receiving mechanical ventilation (MV) may experience ventilator-associated adverse events and have prolonged ICU length of stay (LOS). We conducted a survey on adult patients in the medical ICU requiring MV. Utilizing big data and artificial intelligence (AI)/machine learning, we developed a predictive model to determine the optimal timing for weaning success, defined as no reintubation within 48 hours. An interdisciplinary team integrated AI into our MV weaning protocol...
March 22, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38501327/inpatient-education-reduces-length-of-outpatient-oxygen-therapy-in-bronchopulmonary-dysplasia-a-quality-improvement-project
#2
JOURNAL ARTICLE
Kathryn E K Berlin, Joanne Lagatta, Sara Dawson, Margaret Malnory, William Scott, Alicia Sprecher
BACKGROUND: Patients discharged on home oxygen therapy (HOT) for bronchopulmonary dysplasia (BPD) often receive months of this therapy. A previous trial comparing two methods of HOT weaning showed that increased parent involvement in HOT weaning decreased HOT duration. Our outpatient team uses a standard protocol for outpatient HOT weaning, starting at the first clinic visit 4-6 weeks after discharge. AIM: To shorten HOT duration by teaching parents the outpatient HOT weaning process before neonatal intensive care unit (NICU) discharge...
March 19, 2024: Pediatric Pulmonology
https://read.qxmd.com/read/38490545/can-a-gradual-weaning-and-separation-process-reduce-weaning-distress-in-dam-reared-dairy-calves-a-comparison-with-the-two-step-method
#3
JOURNAL ARTICLE
Anina Vogt, Kerstin Barth, Susanne Waiblinger, Uta König von Borstel
The weaning and separation phase remains one of the biggest challenges for cow-calf-contact systems, but a gradual process that better mimics the naturally occurring reduction in milk intake has not yet been scientifically investigated. Therefore, the aim of our study was to compare behavioral and physiological indicators of distress in 3 mo-old dam-reared dairy calves (with previous full-time cow-calf contact) weaned and separated either via gradual reduction of contact time with the dam (GR, 1 week half day contact, 1 week morning contact, 1 week fence-line contact before complete separation, n = 18) or via 2-step weaning using a nose flap (NF, 2 weeks access to dam with a nose flap, 1 week fence-line contact before complete separation, n = 18)...
March 13, 2024: Journal of Dairy Science
https://read.qxmd.com/read/38487787/a-systematic-approach-to-defining-and-verifying-descriptors-used-in-the-qualitative-behavioural-assessment-of-sows
#4
JOURNAL ARTICLE
Sarah Ibach, Jen-Yun Chou, Monica Battini, Thomas D Parsons
Qualitative Behaviour Assessment (QBA) is a welfare evaluation tool that uses a holistic approach to capturing an animal's emotional state. Lists of QBA descriptors validated to assess pig welfare exist, but their definitions are often not described in peer-reviewed literature and the processes used to develop definitions are lacking. The objective of this study is to detail a systematic approach to creating clear definitions for a pre-existing fixed list of QBA descriptors and test their application. A fixed list of 20 descriptors from the EU Welfare Quality® assessment protocol for pigs was modified, and ten pig experts were recruited to assist with defining these descriptors in a focus group-style discussion...
2024: Animal Welfare
https://read.qxmd.com/read/38473164/effects-of-early-weaning-on-performance-and-carcass-quality-of-nellore-young-bulls
#5
JOURNAL ARTICLE
Gabriela Abitante, Paulo Roberto Leme, Matheus Sousa de Paula Carlis, Germán Darío Ramírez-Zamudio, Bianca Izabelly Pereira Gomes, Luiza Budasz de Andrade, Rodrigo Silva Goulart, Guilherme Pugliesi, Arlindo Saran Netto, Carl Robertson Dahlen, Saulo Luz Silva
This study compared early weaning (EW; 150 days) with conventional weaning (CW; 240 days) in Nellore young bulls, evaluating performance, carcass characteristics, and meat quality. A total of 74 non-castrated male calves were divided into two weaning strategies: EW ( n = 37) and CW ( n = 37). During the growth phase, which lasted 454 ± 14 d for EW calves and 359 ± 16 d for CW calves, animals received a protein-energy supplement at a ratio of 5 g per kg of body weight while grazing Brachiaria brizantha cv...
March 1, 2024: Animals: An Open Access Journal From MDPI
https://read.qxmd.com/read/38472401/pressure-support-ventilation-versus-t-piece-as-spontaneous-breathing-trials-for-extubation-of-patients-with-chronic-obstructive-pulmonary-disease-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#6
JOURNAL ARTICLE
Luiza Mendes Fonseca, Pedro Matos da Câmara, Iane Miguel Pereira Lettieri, Caroline Serafim Dagostin, Arthur Oswaldo de Abreu Vianna
BACKGROUND: Weaning patients with COPD from mechanical ventilation (MV) presents a challenge, as literature on this topic is limited. This study compares PSV and T-piece during spontaneous breathing trials (SBT) in this specific population. METHODS: A search of PubMed, EMBASE, and Cochrane in September 2023 yielded four randomized controlled trials (RCTs) encompassing 560 patients. Among these, 287 (51%) used T-piece during SBTs. RESULTS: The PSV group demonstrated a significant improvement in the successful extubation rate compared to the T-piece (risk ratio [RR] 1...
March 12, 2024: Lung
https://read.qxmd.com/read/38448059/protocol-for-venoarterial-extracorporeal-membrane-oxygenation-to-reduce-morbidity-and-mortality-following-bilateral-lung-transplantation-the-ecmotop-randomised-controlled-trial
#7
JOURNAL ARTICLE
Jonathan Messika, Philippine Eloy, David Boulate, Aude Charvet, Julien Fessler, Jacques Jougon, Philippe Lacoste, Olaf Mercier, Philippe Portran, Hadrien Roze, Edouard Sage, Jacques Thes, Francois Tronc, Mickael Vourc'h, Philippe Montravers, Yves Castier, Herve Mal, Pierre Mordant
INTRODUCTION: Lung transplantation (LTx) aims at improving survival and quality of life for patients with end-stage lung diseases. Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is used as intraoperative support for LTx, despite no precise guidelines for its initiation. We aim to evaluate two strategies of VA-ECMO initiation in the perioperative period in patients with obstructive or restrictive lung disease requiring bilateral LTx. In the control 'on-demand' arm, high haemodynamic and respiratory needs will dictate VA-ECMO initiation; in the experimental 'systematic' arm, VA-ECMO will be pre-emptively initiated...
March 5, 2024: BMJ Open
https://read.qxmd.com/read/38446867/dissolved-oxygen-relevantly-contributes-to-systemic-oxygenation-during-venovenous-extracorporeal-membrane-oxygenation-support
#8
JOURNAL ARTICLE
Michael C Müller, Sarah K Wilke, Andrej Dobbermann, Sascha Kirsten, Martin Ruß, Steffen Weber-Carstens, Tobias Wollersheim
When determining extracorporeal oxygen transfer (VMLO2) during venovenous extracorporeal membrane oxygenation (VV ECMO) dissolved oxygen is often considered to play a subordinate role due to its poor solubility in blood plasma. This study was designed to assess the impact of dissolved oxygen on systemic oxygenation in patients with acute respiratory distress syndrome (ARDS) on VV ECMO support by differentiating between dissolved and hemoglobin-bound extracorporeal oxygen transfer. We calculated both extracorporeal oxygen transfer based on blood gas analysis using the measuring energy expenditure in extracorporeal lung support patients (MEEP) protocol and measured oxygen uptake by the native lung with indirect calorimetry...
March 5, 2024: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://read.qxmd.com/read/38444470/aortic-arch-blood-flow-measurements-as-a-predictor-of-successful-ecmo-weaning-in-cardiogenic-shock
#9
JOURNAL ARTICLE
Antonia Kellnar, Dominik Naumann, Clemens Scherer, Enzo Lüsebrink, Dominik Joskowiak, Sven Peterß, Christian Hagl, Steffen Massberg, Martin Orban, Christopher Stremmel
OBJECTIVE: Acute cardiogenic shock is a life-threatening condition with mortality rates of up to 50%. If conventional therapy fails, veno-arterial extracorporeal membrane oxygenation (VA-ECMO) therapy has emerged to a promising alternative for temporary cardiac and respiratory support in specialized centers. However, it is only a bridge to recovery, final decision, heart transplantation or the permanent implantation of a left ventricular assist device. Therefore, the identification of the optimum weaning time point is challenging, and standardized weaning protocols are rare...
March 15, 2024: Heliyon
https://read.qxmd.com/read/38443603/anti-tumor-necrosis-factor-atnf-weaning-strategy-in-juvenile-idiopathic-arthritis-jia-does-duration-matter
#10
JOURNAL ARTICLE
Kai Liang Teh, Lena Das, Yun Xin Book, Sook Fun Hoh, Xiaocong Gao, Thaschawee Arkachaisri
BACKGROUND: To compare outcomes of a short and long weaning strategy of anti-tumor necrosis factor (aTNF) in our prospective juvenile idiopathic arthritis (JIA) cohort. RESEARCH DESIGN AND METHODS: JIA patients on subcutaneous adalimumab with at least 6 months of follow-up were recruited (May 2010-Jan 2022). Once clinical remission on medication (CRM) was achieved, adalimumab was weaned according to two protocols-short (every 4-weekly for 6 months and stopped) and long (extending dosing interval by 2 weeks for three cycles until 12-weekly intervals and thereafter stopped) protocols...
March 5, 2024: Clinical Rheumatology
https://read.qxmd.com/read/38432702/ventilator-weaning-and-extubation
#11
REVIEW
Karen E A Burns, Bram Rochwerg, Andrew J E Seely
Increasing evidence supports specific approaches to liberate patients from invasive ventilation including the use of liberation protocols, inspiratory assistance during spontaneous breathing trials (SBTs), early extubation of patients with chronic obstructive pulmonary disease to noninvasive ventilation, and prophylactic use of noninvasive support strategies after extubation. Additional research is needed to elucidate the best criteria to identify patients who are ready to undergo an SBT and to inform optimal screening frequency, the best SBT technique and duration, extubation assessments, and extubation decision-making...
April 2024: Critical Care Clinics
https://read.qxmd.com/read/38419587/successful-explantation-of-children-from-the-berlin-heart-excor%C3%A2-ventricular-assist-device-a-systematic-review
#12
REVIEW
Matthew F Mikulski, Swati Iyer, Andrew Well, Carlos M Mery, W Richard Owens, Lauren D Glass, Chesney D Castleberry, Charles D Fraser
BACKGROUND: The Berlin Heart EXCOR® (BHE) can bridge children with severe heart failure to transplantation, but some are successfully weaned and spared transplantation. This study seeks to identify characteristics of children amenable to successful explantation with BHE support. METHODS: Preferred Reporting Items for Systematic reviews and Meta-Analyses 2020 guidelines were used. Five databases were screened for original, English articles measuring BHE support in patients <18 years old based on title and abstract...
February 29, 2024: Artificial Organs
https://read.qxmd.com/read/38407536/seizures-in-3-juvenile-dogs-after-intravenous-anesthetic-drug-withdrawal-during-weaning-from-mechanical-ventilation-suspected-to-be-a-sign-of-iatrogenic-withdrawal-syndrome
#13
JOURNAL ARTICLE
Kaitlyn Dreese, Kellyann Murphy, Jasper Burke, Deborah C Silverstein
OBJECTIVE: To describe seizure activity in juvenile dogs successfully weaned from long-term mechanical ventilation. CASE SERIES SUMMARY: Three juvenile dogs (all approximately 3 months old) underwent long-term mechanical ventilation with IV anesthesia for suspected noncardiogenic pulmonary edema. Within 24 hours of extubation and within 10 hours of discontinuing midazolam continuous infusions, all dogs experienced seizures, which is 1 sign of iatrogenic withdrawal syndrome...
February 26, 2024: Journal of Veterinary Emergency and Critical Care
https://read.qxmd.com/read/38395393/graduate-student-literature-review-social-and-feeding-behavior-of-group-housed-dairy-calves-in-automated-milk-feeding-systems
#14
REVIEW
Maria E Montes, Jacquelyn P Boerman
Automated milk feeders (AMF) allow farmers to raise calves in groups while generating individual records on milk consumption, drinking speed, and frequency of visits. Calves raised in groups benefit from social interaction, which facilitates learning and adapting to novelty. However, calves in large groups (>12 calves/feeder) experience a higher risk of disease transmission and competition than those housed individually or in smaller groups. Therefore, if group size, grouping strategy, and disease detection are not optimal, the health and performance of calves can be compromised...
February 21, 2024: Journal of Dairy Science
https://read.qxmd.com/read/38391855/development-and-effect-evaluation-of-an-action-oriented-interdisciplinary-weaning-protocol-for-cuffed-tracheostomy-tubes-in-patients-with-acquired-brain-injury
#15
JOURNAL ARTICLE
Katje Bjerrum, Linda-Maria Delgado Grove, Sine Secher Mortensen, Jesper Fabricius
The objective was to develop an interdisciplinary weaning protocol (IWP) for patients with tracheostomy tubes due to acquired brain injury, and to effect evaluate implementation of the IWP on decannulation rates and weaning duration. An expert panel completed a literature review in 2018 to identify essential criteria in the weaning process. Based on consensus and availability in clinical practice, criteria for guiding the weaning process were included in the protocol. Using the IWP, dysphagia is graded as either severe, moderate, or mild...
February 16, 2024: Healthcare (Basel, Switzerland)
https://read.qxmd.com/read/38388259/structured-weaning-from-the-impella-left-ventricular-micro-axial-pump-in-acute-myocardial-infarction-with-cardiogenic-shock-and-protected-percutaneous-coronary-intervention-experience-from-a-non-cardiac-surgical-centre
#16
JOURNAL ARTICLE
Ryan J Slack, Forbes McGain, Nicholas Cox, Craig French, Victoria Cheng, Dion Stub, Brian Zakhem, Fabien Dade, Jason E Bloom, William Chan, Yang Yang
BACKGROUND: The Impella (Abiomed, Danvers, MA, USA) temporary percutaneous left ventricular assist device is increasingly used as mechanical circulatory support in patients with acute myocardial infarction-cardiogenic shock (AMICS) or those undergoing high-risk protected percutaneous coronary intervention (PCI). The optimal weaning regimen remains to be defined. METHOD: We implemented a structured weaning protocol in a series of 10 consecutive patients receiving Impella support for protected PCI or AMICS treated with PCI in a high volume non-cardiac surgery centre...
February 21, 2024: Heart, Lung & Circulation
https://read.qxmd.com/read/38367943/a-high-salt-intake-in-early-life-affects-stress-coping-response-in-males-but-not-in-female-rats
#17
JOURNAL ARTICLE
M W Lago, L S Marques, Juliano T K Jung, V Felipeto, C W Nogueira
Eating diets high in salt has been associated with alterations in the immune system and the potential development of neuropsychiatric disorders. This area of research shows promise, but there is currently a limited amount of research on this topic. The present study investigated whether a high salt diet (HSD) affects anhedonia and stress-coping response behaviors in young male and female Wistar rats. In this study, male and female Wistar rats were fed an HSD (8% NaCl w/w) from weaning to post-natal day (PND) 64...
February 15, 2024: Physiology & Behavior
https://read.qxmd.com/read/38320925/inspiratory-muscle-training-for-mechanically-ventilated-patients-in-the-intensive-care-unit-obstacles-and-facilitators-for-implementation-a-mixed-method-quality-improvement-study
#18
JOURNAL ARTICLE
Mel E Major, Juultje Sommers, Esther Horrevorts, Carmen M Buist, Daniela S Dettling-Ihnenfeldt, Marike van der Schaaf
BACKGROUND: Mechanically ventilated patients are at risk of developing inspiratory muscle weakness (IMW), which is associated with failure to wean and poor outcomes. Inspiratory muscle training (IMT) is a recommended intervention during and after extubation but has not been widely adopted in Dutch intensive care units (ICUs). OBJECTIVES: The objective of this study was to explore the potential, barriers, and facilitators for implementing IMT as treatment modality for mechanically ventilated patients...
February 6, 2024: Australian Critical Care: Official Journal of the Confederation of Australian Critical Care Nurses
https://read.qxmd.com/read/38310282/the-cotton-swab-method-an-accurate-and-less-invasive-way-to-assess-fecal-consistency-in-weaned-pigs
#19
JOURNAL ARTICLE
Esben Østergaard Eriksen, Martin Friis Sejersen, Ken Steen Pedersen
BACKGROUND: Researchers and pig veterinarians are interested in assessing pigs' fecal consistency. This study developed a standardized protocol and scale for the cotton swab method, which is a way of assessing the fecal consistency in pigs. The accuracy of the cotton swab method was evaluated in weaned pigs using fecal dry-matter analysis as a golden standard. The study also proposed fecal dry-matter percentage thresholds for the categorization of fecal consistency on a four-point scale...
February 3, 2024: BMC Veterinary Research
https://read.qxmd.com/read/38291421/awareness-and-practice-of-airway-pressure-release-ventilation-mode-in-acute-respiratory-distress-syndrome-patients-among-nurses-in-saudi-arabia
#20
JOURNAL ARTICLE
Abdulelah M Aldhahir, Abdullah A Alqarni, Mohammed A Madkhali, Hussain H Madkhali, Abdullah A Bakri, Mohammad A Shawany, Ahmed H Alasimi, Abdullah S Alsulayyim, Jaber S Alqahtani, Mohammed M Alyami, Saeed M Alghamdi, Omar A Alqarni, Ali Hakamy
BACKGROUND: This study aimed to assess the knowledge and current practice of using the airway pressure release ventilation (APRV) mode with acute respiratory distress syndrome (ARDS) patients and identify barriers to not using this mode of ventilation among nurses who work in critical areas in Saudi Arabia. METHODS: Between December 2022 and April 2023, a cross-sectional online survey was disseminated to nurses working in critical care areas in Saudi Arabia. The characteristics of the respondents were analyzed using descriptive statistics...
January 30, 2024: BMC Nursing
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