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Castells, Maria

María Pilar de Lara-Castells, Alexander O Mitrushchenkov
A first-principles study of the spectroscopy of a single hydrogen molecule rotating inside and outside of carbon nanotubes is presented. Density functional theory (DFT)-based symmetry-adapted perturbation theory (SAPT) is applied to analyze the influence of the rotation in the dispersionless and dispersion energy contributions to the adsorbate-nanotube interaction. A potential model for the H2-nanotube interaction is proposed and applied to derive the molecular energy levels of the rotating hydrogen molecule...
August 17, 2018: Physical Chemistry Chemical Physics: PCCP
Eytan Ben-Ami, Maria C Castells, Nathan T Connell, Anna E Rutherford, Katherine A Thornton
Drug reaction with eosinophilia and systemic symptoms (DRESS) is a severe, potentially life-threatening drug-induced hypersensitivity reaction, characterized by cutaneous eruptions, fever, diffuse lymphadenopathy, along with hypereosinophilia, and elevated liver function tests, which in severe cases may lead to fulminant hepatic failure and death. Although DRESS syndrome has been associated with over 50 different drugs including imatinib, it has never been reported in association with imatinib treatment in solid tumors...
August 9, 2018: Anti-cancer Drugs
Daniel Rodríguez-Alcalde, Sabela Carballal, Leticia Moreira, Luis Hernández, Lorena Rodríguez-Alonso, Francisco Rodríguez-Moranta, Victoria Gonzalo, Luis Bujanda, Xavier Bessa, Carmen Poves, Joaquín Cubiella, Inés Castro, Mariano González, Eloísa Moya, Susana Oquiñena, Joan Clofent, Enrique Quintero, Pilar Esteban, Virginia Piñol, Francisco Javier Fernández, Rodrigo Jover, Lucía Cid, Esteve Saperas, María López-Cerón, Miriam Cuatrecasas, Jorge López-Vicente, Liseth Rivero-Sánchez, Gerhard Jung, María Vila-Casadesús, Ariadna Sánchez, Antoni Castells, María Pellisé, Francesc Balaguer
BACKGROUND:  Serrated polyposis syndrome (SPS) has been associated with an increased risk of colorectal cancer (CRC). Accordingly, intensive surveillance with annual colonoscopy is advised. The aim of this multicenter study was to describe the risk of advanced lesions in SPS patients undergoing surveillance, and to identify risk factors that could guide the prevention strategy. METHODS:  From March 2013 to April 2015, 296 patients who fulfilled criteria I and/or III for SPS were retrospectively recruited at 18 centers...
August 1, 2018: Endoscopy
Rocío Casañas, Victoria-Mailen Arfuch, Pere Castellví, Juan-José Gil, Maria Torres, Angela Pujol, Gemma Castells, Mercè Teixidó, Maria Teresa San-Emeterio, Hernán María Sampietro, Aleix Caussa, Jordi Alonso, Lluís Lalucat-Jo
BACKGROUND: One half of adults who develop any mental disorder do so during adolescence. Previous literature showed that Mental Health Literacy (MHL) interventions impact mental health knowledge, reduce the associated stigma, and promote help-seeking among the adolescent population. However, evidence for the effectiveness and cost-effectiveness of these programmes remains inconclusive. The aim of this paper is to present a study protocol that evaluates the effectiveness of the " EspaiJove...
July 31, 2018: BMC Public Health
Cristina Ornelas, Joana Caiado, Alcinda Campos Melo, Manuel Pereira Barbosa, Mariana C Castells, Maria Conceição Pereira Dos Santos
Cytostatics, mainly oxaliplatin, are widely used to treat oncological diseases. There has been an increase in hypersensitivity reactions to these drugs, mostly IgE-mediated. Skin tests are the main diagnostic method used but they may induce irritant local reactions and contamination by health care professionals. The main goals of this work were to evaluate the contribution of the basophil activation test (BAT) as a diagnostic tool for hypersensitivity reactions to oxaliplatin, and to compare the expression of CD63 and CD203c molecules...
July 24, 2018: International Archives of Allergy and Immunology
Rosa Puigpinós-Riera, Adán Castillo Gómez, Anabel Romero Morales, Marta Aller, Xavier Castells, María Sala
OBJECTIVE: To describe and analyse the factors associated with the use of health services (emergency departments, admissions and primary care) in women survivors of breast cancer diagnosed or treated in four university hospitals of Barcelona (Spain) between 2003 and 2013, within the framework of the Cohort DAMA project. METHOD: Descriptive design nested in a mixed cohort (Cohort Dama). We obtained sociodemographic information and information on the use of health services through a questionnaire, and on the tumour from the clinical history...
July 18, 2018: Gaceta Sanitaria
Hanna Tolonen, Päivikki Koponen, Ala'a Al-Kerwi, Nada Capkova, Simona Giampaoli, Jennifer Mindell, Laura Paalanen, Maria Ruiz-Castell, Antonia Trichopoulou, Kari Kuulasmaa
Background: Representative and reliable data on health and health determinants of the population and population sub-groups are needed for evidence-informed policy making; planning and evaluation of prevention programmes; and research. Health examination surveys (HESs) including questionnaires, objective health measurements and analysis of biological samples, provide information on many health indicators that are available not at all or less reliably or completely through administrative registers or health interview surveys...
2018: Archives of Public Health, Archives Belges de Santé Publique
Ana Gutiérrez-Hervás, Ernesto Cortés-Castell, Mercedes Juste-Ruíz, Antonio Palazón-Bru, Vicente Gil-Guillén, María Mercedes Rizo-Baeza
INTRODUCTION: interpretation of accelerometer-derived physical activity in preschool children is confounded by differences in cut-off points. AIM: the purpose of this study was to analyze physical activity in 2-to-7-year-old children to establish reference values for daily activity. METHODS: observational study in children aged 2-7 years, without chronic diseases and whose parents provided informed consent. The main variable was physical activity, measured continuously over 120 hours (three workdays and two weekend days) by accelerometer...
June 27, 2018: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
María Pilar de Lara-Castells, Carlos Cabrillo, David A Micha, Alexander O Mitrushchenkov, Tijo Vazhappilly
A first-principles study of the stability and optical response of subnanometer silver clusters Agn (n ≤ 5) on a TiO2(110) surface is presented. First, the adequacy of the vdW-corrected DFT-D3 approach is assessed using the domain-based pair natural orbital correlation DLPNO-CCSD(T) calculations along with the Symmetry-Adapted Perturbation Theory [SAPT(DFT)] applied to a cluster model. Next, using the DFT-D3 treatment with a periodic slab model, we analyze the interaction energies of the atomic silver clusters with the TiO2(110) surface...
July 18, 2018: Physical Chemistry Chemical Physics: PCCP
Christian Manzardo, Maria C Londoño, Lluis Castells, Milagros Testillano, José Luis Montero, Judit Peñafiel, Marta Subirana, Ana Moreno, Victoria Aguilera, María Luisa González-Diéguez, Jorge Calvo-Pulido, Xavier Xiol, Magdalena Salcedo, Valentin Cuervas-Mons, José Manuel Sousa, Francisco Suarez, Trinidad Serrano, Jose Ignacio Herrero, Miguel Jiménez, José R Fernandez, Carlos Giménez, Santos Del Campo, Juan I Esteban-Mur, Gonzalo Crespo, Asunción Moreno, Gloria de la Rosa, Antoni Rimola, Jose M Miro
Direct-acting antivirals have proved to be highly efficacious and safe in monoinfected liver transplant (LT) recipients who experience recurrence of hepatitis C virus (HCV) infection. However, there is a lack of data on effectiveness and tolerability of these regimens in HCV/HIV-coinfected patients who experience recurrence of HCV infection after LT. In this prospective, multicenter cohort study, the outcomes of 47 HCV/HIV-coinfected LT patients who received DAAs therapy (with or without ribavirin [RBV]) were compared with those of a matched cohort of 148 HCV-monoinfected LT recipients who received similar treatment...
July 2, 2018: American Journal of Transplantation
Maria Del Mar Rigo-Adrover, Kees van Limpt, Karen Knipping, Johan Garssen, Jan Knol, Adele Costabile, Àngels Franch, Margarida Castell, Francisco José Pérez-Cano
Rotavirus (RV) causes morbidity and mortality among infants worldwide, and there is evidence that probiotics and prebiotics can have a positive influence against infective processes such as that due to RV. The aim of this study was to evidence a preventive role of one prebiotic mixture (of short-chain galactooligosaccharide/long-chain fructooligosaccharide), the probiotic Bifidobacterium breve M-16V and the combination of the prebiotic and the probiotic, as a synbiotic, in a suckling rat double-RV infection model...
2018: Frontiers in Immunology
Lluis Serra-Majem, António Raposo, Javier Aranceta-Bartrina, Gregorio Varela-Moreiras, Caomhan Logue, Hugo Laviada, Susana Socolovsky, Carmen Pérez-Rodrigo, Jorge Antonio Aldrete-Velasco, Eduardo Meneses Sierra, Rebeca López-García, Adriana Ortiz-Andrellucchi, Carmen Gómez-Candela, Rodrigo Abreu, Erick Alexanderson, Rolando Joel Álvarez-Álvarez, Ana Luisa Álvarez Falcón, Arturo Anadón, France Bellisle, Ina Alejandra Beristain-Navarrete, Raquel Blasco Redondo, Tommaso Bochicchio, José Camolas, Fernando G Cardini, Márcio Carocho, Maria do Céu Costa, Adam Drewnowski, Samuel Durán, Víctor Faundes, Roxana Fernández-Condori, Pedro P García-Luna, Juan Carlos Garnica, Marcela González-Gross, Carlo La Vecchia, Rosaura Leis, Ana María López-Sobaler, Miguel Agustín Madero, Ascensión Marcos, Luis Alfonso Mariscal Ramírez, Danika M Martyn, Lorenza Mistura, Rafael Moreno Rojas, José Manuel Moreno Villares, José Antonio Niño-Cruz, María Beatriz P P Oliveira, Nieves Palacios Gil-Antuñano, Lucía Pérez-Castells, Lourdes Ribas-Barba, Rodolfo Rincón Pedrero, Pilar Riobó, Juan Rivera Medina, Catarina Tinoco de Faria, Roxana Valdés-Ramos, Elsa Vasco, Sandra N Wac, Guillermo Wakida, Carmina Wanden-Berghe, Luis Xóchihua Díaz, Sergio Zúñiga-Guajardo, Vasiliki Pyrogianni, Sérgio Cunha Velho de Sousa
International scientific experts in food, nutrition, dietetics, endocrinology, physical activity, paediatrics, nursing, toxicology and public health met in Lisbon on 2⁻4 July 2017 to develop a Consensus on the use of low- and no-calorie sweeteners (LNCS) as substitutes for sugars and other caloric sweeteners. LNCS are food additives that are broadly used as sugar substitutes to sweeten foods and beverages with the addition of fewer or no calories. They are also used in medicines, health-care products, such as toothpaste, and food supplements...
June 25, 2018: Nutrients
Hanen Samouda, Maria Ruiz-Castell, Valery Bocquet, Andrea Kuemmerle, Anna Chioti, Frédéric Dadoun, Ngianga-Bakwin Kandala, Saverio Stranges
The analyses of geographic variations in the prevalence of major chronic conditions, such as overweight and obesity, are an important public health tool to identify "hot spots" and inform allocation of funding for policy and health promotion campaigns, yet rarely performed. Here we aimed at exploring, for the first time in Luxembourg, potential geographic patterns in overweight/obesity prevalence in the country, adjusted for several demographic, socioeconomic, behavioural and health status characteristics...
2018: PloS One
Carolina Mangas-Sanjuan, Pedro Zapater, Joaquín Cubiella, Óscar Murcia, Luis Bujanda, Vicent Hernández, David Martínez-Ares, María Pellisé, Agustín Seoane, Ángel Lanas, David Nicolás-Pérez, Alberto Herreros-de-Tejada, María Chaparro, Guillermo Cacho, Servando Fernández-Díez, José-Carlos Marín-Gabriel, Enrique Quintero, Antoni Castells, Rodrigo Jover
Background: Guidelines recommend surveillance colonoscopies based exclusively on findings at baseline colonoscopy. This recommendation leads to the paradox that the higher the baseline colonoscopy quality, the more surveillance colonoscopies will be indicated according to current guidelines. Objective: The aim of this study was to evaluate the effect on follow-up findings of different quality metrics of the endoscopist performing the baseline colonoscopy. Methods: This retrospective cohort study included individuals with advanced adenomas at baseline colonoscopy...
May 2018: United European Gastroenterology Journal
Noelia Gómez-Aguirre, Daniel Fuertes-Ruiz, Borja Gracia-Tello, Carolina Clemente-Sarasa, Ester Artajona-Rodrigo, José-Luis Cabrerizo-García, Begoña de Escalante-Yangüela, María-Carmen Bueno-Castel, José Velilla-Marco, Jesús Díez-Manglano
OBJECTIVE: To externally validate the PALIAR index for patients with advanced, nononcologic chronic diseases. METHODS: We performed a prospective, multicenter cohort study that included patients with advanced, nononcologic chronic diseases hospitalized in internal medicine departments and treated consecutively by the researchers between July 1st and December 31st, 2014. Data were collected from each patient on age, sex, advanced disease, Charlson index, comorbidities, Barthel index, terminal illness symptoms, need for caregiver, hospitalization in the past 3 and 12 months and number of drugs...
June 6, 2018: Aging Clinical and Experimental Research
David Couto-Mallón, Francisco González-Vílchez, Luis Almenar-Bonet, Beatriz Díaz-Molina, Javier Segovia-Cubero, José González-Costello, Juan Delgado-Jiménez, María A Castel-Lavilla, María G Crespo-Leiro, Diego Rangel-Sousa, Manuel Martínez-Sellés, Gregorio Rábago-Juan-Aracil, Luis De-la-Fuente-Galán, Teresa Blasco-Peiró, Daniela Hervás-Sotomayor, Iris P Garrido-Bravo, Sonia Mirabet-Pérez, Javier Muñiz, Eduardo Barge-Caballero
INTRODUCTION AND OBJECTIVES: To study the prognostic value of serum lactate in patients under temporary preoperative mechanical circulatory support who underwent urgent heart transplant. METHODS: We conducted a subanalysis of a Spanish multicenter registry recording data on patients under temporary mechanical circulatory support listed for highly urgent heart transplant from 2010 to 2015. Participants selected for the present study were those who received a transplant and who had known preoperative serum lactate levels...
May 30, 2018: Revista Española de Cardiología
Laila S Garro, Marcelo V Aun, Iracy Sílvia C Soares, Marisa R Ribeiro, Antônio A Motta, Jorge Kalil, Mariana C Castells, Maria José C Carmona, Pedro Giavina-Bianchi
OBJECTIVE: To assess the incidence of intra-operative immediate hypersensitivity reactions and anaphylaxis. METHODS: A cross-sectional observational study was conducted at the Department of Anesthesiology, University of São Paulo School of Medicine, Hospital das Clínicas, São Paulo, Brazil, from January to December 2010. We developed a specific questionnaire to be completed by anesthesiologists. This tool included questions about hypersensitivity reactions during anesthesia and provided treatments...
May 17, 2018: Clinics
María Barroso, Silvia Pérez-Fernández, M Mar Vila, M Dolors Zomeño, Ruth Martí-Lluch, Ferran Cordon, Rafel Ramos, Roberto Elosua, Irene R Degano, Montse Fitó, Carmen Cabezas, Gemma Salvador, Conxa Castell, María Grau
Background: The validity of a cardiovascular risk self-screening method was assessed. The results obtained for self-measurement of blood pressure, a point-of-care system's assessment of lipid profile and glycated hemoglobin, and a self-administered questionnaire (sex, age, diabetes, tobacco consumption) were compared with the standard screening (gold standard) conducted by a health professional. Methods: Crossover clinical trial on a population-based sample from Girona (north-eastern Spain), aged 35-74, with no cardiovascular disease at recruitment...
2018: Clinical Epidemiology
Emilce Trucco, José María Tolosana, Elena Arbelo, Ada Doltra, María Ángeles Castel, Eva Benito, Roger Borràs, Eduard Guasch, Silvia Vidorreta, Barbara Vidal, Silvia Montserrat, Marta Sitges, Antonio Berruezo, Josep Brugada, Lluís Mont
OBJECTIVES: The aim of this study was to compare patient response to cardiac resynchronization therapy (CRT) using fusion-optimized atrioventricular (AV) and interventricular (VV) intervals versus nominal settings. BACKGROUND: The additional benefit obtained by AV- and VV-interval optimization in patients undergoing CRT remains controversial. Previous studies show short-term benefit in hemodynamic parameters; however, midterm randomized comparison between electrocardiogram optimization and nominal parameters is lacking...
February 2018: JACC. Clinical Electrophysiology
Olivia Ferrández, Borja Casañ, Santiago Grau, Javier Louro, Esther Salas, Xavier Castells, Maria Sala
OBJECTIVE: To describe drug-related problems identified in hospitalized patients and to assess physicians' acceptance rate of pharmacists' recommendations. METHODS: Retrospective observational study that included all drug-related problems detected in hospitalized patients during 2014-2015. Statistical analysis included a descriptive analysis of the data and a multivariate logistic regression to evaluate the association between pharmacists' recommendation acceptance rate and the variable of interest...
May 7, 2018: Gaceta Sanitaria
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