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Low dosis medicine

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https://www.readbyqxmd.com/read/30107345/diffusion-ordered-spectroscopy-on-a-benchtop-spectrometer-for-drug-analysis
#1
Gaëtan Assemat, Boris Gouilleux, Dylan Bouillaud, Jonathan Farjon, Véronique Gilard, Patrick Giraudeau, Myriam Malet-Martino
The first reported two-dimensional diffusion-ordered spectroscopy (DOSY) experiments were recorded at low field (LF) on a benchtop NMR spectrometer using the BPP-STE-LED (bipolar pulse pair-stimulated echo sequence with a longitudinal eddy current delay) pulse sequence which limits phase anomalies and baseline discrepancies. A LF DOSY map was first obtained from a solution of a model pharmaceutical formulation containing a macromolecule and an active pharmaceutical ingredient. It revealed a clear separation between the components of the mixture and gave apparent diffusion coefficients (ADC) values consistent with those measured from the reference high field experiment...
August 6, 2018: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/21488364/-ukrainian-break-through-in-the-european-and-world-strategy-of-individual-prophylaxis-of-ischemic-stroke-in-patients-with-arterial-hypertension
#2
S M Tolstopiatov
To reduce of epidemic of an ischemic stroke often developed in patients with arterial hypertension, we have developed the program of individual diagnostics of a clinical risk factor and a method to optimize the treatment directed on prophylactic of cardio-vascular complications. The main predictor of blood clot formation, hypercoagulation, had been detected by means of our laboratory technology "Coaguloscop-TC" (Ukraine patent) which allows registration 36 biomarkers of coagulation cascade and the fibrinolysys system...
July 2010: Likars'ka Sprava
https://www.readbyqxmd.com/read/10815457/-investigation-of-the-urinary-tract-in-children-in-nuclear-medicine
#3
REVIEW
A Boubaker, A B Delaloye
The early detection of urologic abnormalities by antenatal sonography has resulted in the investigation of many infants and neonates for suspicion of either obstructive uropathy or reflux nephropathy. Nuclear medicine techniques allow to assess renal parenchyma integrity, to detect pyelonephritic scars and to measure absolute and relative renal function; these methods are easy to perform and reproducible, without any sedation, repeated venous punctures or bladder catheterization. Furthermore, the use of dynamic tubular tracers and frusemide test is a very usefull method which can differentiate between upper and/or lower urinary tract obstruction and determine the degree of obstruction (severe or incomplete) in order to plan for surgery or conservative treatment...
March 2000: Revue Médicale de la Suisse Romande
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