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https://www.readbyqxmd.com/read/30008587/hyperbaric-oxygen-therapy-in-liver-diseases
#1
REVIEW
Yun Sun, Yankai Wen, Chanjuan Shen, Yuanrun Zhu, Wendong You, Yuanyuan Meng, Lijuan Chen, Yiping Feng, Xiaofeng Yang, Zuo-Bing Chen
Hyperbaric oxygen therapy (HBOT) is an efficient therapeutic option to improve progress of lots of diseases especially hypoxia-related injuries, and has been clinically established as a wide-used therapy for patients with carbon monoxide poisoning, decompression sickness, arterial gas embolism, problematic wound, and so on. In the liver, most studies positively evaluated HBOT as a potential therapeutic option for liver transplantation, acute liver injury, nonalcoholic steatohepatitis, fibrosis and cancer, especially for hepatic artery thrombosis...
2018: International Journal of Medical Sciences
https://www.readbyqxmd.com/read/29987845/interventions-for-the-treatment-of-brain-radionecrosis-after-radiotherapy-or-radiosurgery
#2
REVIEW
Caroline Chung, Andrew Bryant, Paul D Brown
BACKGROUND: Brain radionecrosis (tissue death caused by radiation) can occur following high-dose radiotherapy to brain tissue and can have a significant impact on a person's quality of life (QoL) and function. The underlying pathophysiological mechanism remains unclear for this condition, which makes establishing effective treatments challenging. OBJECTIVES: To assess the effectiveness of interventions used for the treatment of brain radionecrosis in adults over 18 years old...
July 9, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29979089/clinical-trials-targeting-hypoxia
#3
Hannah Tharmalingham, Peter Hoskin
The concept of tumour hypoxia as a cause of radiation resistance has been prevalent for over 100 years. During this time, our understanding of tumour hypoxia has matured with the recognition that oxygen tension within a tumour is influenced by both diffusion and perfusion mechanisms. In parallel, clinical strategies to modify tumour hypoxia with the expectation that this will improve response to radiation have been developed and tested in clinical trials. Despite many disappointments, meta-analysis of the data on hypoxia modification confirms a significant impact on both tumour control and survival...
July 6, 2018: British Journal of Radiology
https://www.readbyqxmd.com/read/29915804/using-advanced-wound-care-and-hyperbaric-oxygen-to-manage-wound-complications-following-treatment-of-vulvovaginal-carcinoma
#4
C Griffiths, R S Howell, H Boinpally, E Jimenez, E Chalas, F Musa, S Gorenstein
Postoperative management of patients with vulvar cancer is associated with a high incidence of poor wound healing and radiation -induced late tissue necrosis. This case series demonstrates the impact on wound healing with the use of hyperbaric oxygen therapy and advanced wound care following radical vulvectomy and/or radiation therapy. A retrospective case series was performed of all patients from 2016 to 2017 with lower genital cancer who underwent radical surgery with or without chemoradiation treatment, experienced wound dehiscence or late tissue radionecrosis, and were treated with advanced wound care, including hyperbaric oxygen therapy (HBO)...
May 2018: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/29913945/prevention-and-treatment-of-trismus-in-head-and-neck-cancer-a-case-report-and-a-systematic-review-of-the-literature
#5
Piotr Wranicz, Bente Brokstad Herlofson, Jan F Evensen, Ulf E Kongsgaard
Introduction Trismus, or limited mouth opening, is a well-known complication of head and neck cancer and its treatment. It may be caused by tumour infiltration into the masticatory muscles or by treatment like surgery and radiotherapy. A limited mouth opening may have a negative effect on nutrition, phonation, dental hygiene and treatment, and quality of life. The severity of this complication depends on the location of the tumour, the type of reconstruction, the total radiation dose, fractionation, and treatment techniques...
April 1, 2010: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29877702/synergizing-upconversion-nanophotosensitizers-with-hyperbaric-oxygen-to-remodel-the-extracellular-matrix-for-enhanced-photodynamic-cancer-therapy
#6
Jingqiu Li, Jinzhao Huang, Yanxiao Ao, Shiyu Li, Yu Miao, Zhongzheng Yu, Lingtao Zhu, Xiaoli Lan, Yanhong Zhu, Yan Zhang, Xiangliang Yang
Photodynamic therapy (PDT) holds great promise as a noninvasive and selective cancer therapeutic treatment in preclinical research and clinical practice; however, it has limited efficacy in the ablation of deep-seated tumor because of hypoxia-associated circumstance and poor penetration of photosensitizers to cancer cells away from the blood vessels. To tackle the obstacles, we propose a therapeutic strategy that synergizes upconversion nanophotosensitizers (UNPSs) with hyperbaric oxygen (HBO) to remodel the extracellular matrix for enhanced photodynamic cancer therapy...
July 11, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29727306/modern-management-of-osteoradionecrosis
#7
Blake S Raggio, Ryan Winters
PURPOSE OF REVIEW: Despite recent advances in radiotherapy, osteoradionecrosis (ORN) remains a common and difficult complication of radiation therapy in head and neck cancer patients. Available treatment options are complementary to its complex pathophysiology and the currently available theories of ORN development. The efficacy of hyperbaric oxygen therapy has recently been questioned, and therapies targeting the fibroatrophic process have become a focus of ORN treatment. The objective of this review is to evaluate the literature regarding ORN of the mandible, with a focus on available treatment options...
August 2018: Current Opinion in Otolaryngology & Head and Neck Surgery
https://www.readbyqxmd.com/read/29665051/hyperbaric-oxygen-treatment-sensitizes-gastric-cancer-cells-to-melatonin-induced-apoptosis-through-multiple-pathways
#8
Xiang Wei, Yinliang Qi, Ning Jia, Qing Zhou, Sumei Zhang, Yuan Wang
Although extensive efforts have been made in recent decades to treat advanced gastric cancer with comprehensive therapy based on chemotherapy, effective anti-gastric cancer therapeutics are still lacking in the clinics. Therefore, potent novel anti-gastric cancer ways are greatly needed. Here, we explored hyperbaric oxygen treatment as a novel and effective adjuvant treatment method which has anti-gastric cancer effects when used together with melatonin. When performed together with MLT, HBO effectively inhibited tumorigenicity of gastric cancer through selectively inducing a robust tumor suppressive apoptosis response...
August 2018: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/29571229/hyperbaric-oxygen-therapy-as-adjuvant-for-treating-wound-complications-after-extensive-resection-for-vulvar-malignancy
#9
André Lopes, Ronaldo Lúcio Rangel Costa, Gabriel Lowndes de Souza Pinto, Mariana Camargo Guimarães Forghieri, Ailma Larrè, Thais Gomes de Almeida, Carla Baltazar de Souza, Vivian Sartorelli, Francisco Ricardo Gualda Coelho, José Ribamar Branco
Introduction: Necrosis, wound breakdown, and infection represent major complications associated with radical vulvectomy. We aimed to analyze the feasibility of hyperbaric oxygen (HBO₂) therapy as an adjunctive treatment for such complications. Methods: We performed a retrospective analysis of the medical records, clinical charts, and operative records of vulvar cancer patients who underwent hyperbaric oxygen therapy after extensive surgical resection in our institute between 2012 and 2016, with a comparison of the clinical outcomes of patients with similar surgical procedures andsevere wound complications who did not undergo HBO₂...
January 2018: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/29426738/long-term-success-of-dental-implants-in-patients-with-head-and-neck-cancer-after-radiation-therapy
#10
M M Curi, A F B Condezo, K D C B Ribeiro, C L Cardoso
The purpose of this study was to analyze the long-term success and factors potentially influencing the success of dental implants placed in patients with head and neck cancer who underwent radiation therapy with a minimum total dose of 50Gy during the years 1995-2010. Thirty-five patients (169 dental implants) were included in this study. Data on demographic characteristics, tumour type, radiation therapy, implant sites, implant dimensions, and hyperbaric oxygen therapy (HBOT) were obtained from the medical records and analyzed...
June 2018: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29326769/osteoradionecrosis-in-subaxial-cervical-spine-a-rare-and-devastating-complication-a-case-report
#11
M Z Rashid, M H Ariffin, S A Rhani, A Baharudin, K Ibrahim
Osteoradionecrosis, a rare complication of radiation therapy, is a slow progression disease which affects the surrounding structures of spinal components. It essentially weakens the soft tissue and bony configuration and can cause nerve impingement or cord compression. We describe a patient who underwent radiotherapy for thyroid cancer and presented with cervical kyphosis with anterolisthesis of C3/C4 and C4/C5 some 32 years later. We explore the role of anterior and posterior fusion, as well as hyperbaric oxygen therapy in promoting healing...
November 2017: Malaysian Orthopaedic Journal
https://www.readbyqxmd.com/read/29302697/-laser-and-light-therapy-for-treatment-of-radiation-dermatitis
#12
REVIEW
H-J Laubach, J Robijns
Radiation dermatitis (RD), an inflammatory skin disease that can be an unwanted side effect of medical radiation therapy (RT), most commonly occurs in patients undergoing cancer of the ENT, anal, and vulvar regions. The side effects on the skin and mucous membranes occur within a few weeks after the initiation of RT; however, late side effects can develop months to years after the RT. Therapeutically, various treatment approaches are considered such as pentoxifylline, hyperbaric oxygen therapy, laser therapy, and PBMT...
January 2018: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/29286175/hyperbaric-oxygen-therapy-an-alternative-treatment-for-radiation-induced-cutaneous-ulcers
#13
Inés Fernández Canedo, Laura Padilla España, José Francisco Millán Cayetano, Juan Bosco Repiso Jiménez, Manuel Pérez Delgado, Magdalena de Troya Martín
Radiotherapy is a widely recognised treatment for non-melanoma skin cancer. We report three cases of radiation-induced skin ulcers in which hyperbaric oxygen therapy was administered in 90-min sessions, 5 days a week at 2.4 absolute atmospheres in a multiplace hyperbaric chamber. Hyperbaric oxygen therapy is an outpatient treatment that does not displace other classical treatments and may be used as an adjunct therapy.
December 29, 2017: Australasian Journal of Dermatology
https://www.readbyqxmd.com/read/29123016/the-use-of-hyperbaric-oxygen-for-the-prevention-and-management-of-osteoradionecrosis-of-the-jaw-a-dana-farber-brigham-and-women-s-cancer-center-multidisciplinary-guideline
#14
Ahmed Sultan, Glenn J Hanna, Danielle N Margalit, Nicole Chau, Laura A Goguen, Francisco M Marty, Guilherme Rabinowits, Jonathan D Schoenfeld, Stephen T Sonis, Tom Thomas, Roy B Tishler, Nathaniel S Treister, Alessandro Villa, Sook-Bin Woo, Robert Haddad, Hani Mawardi
No abstract text is available yet for this article.
November 2017: Oncologist
https://www.readbyqxmd.com/read/29088868/pulmonary-function-impairment-predicted-poor-prognosis-of-patients-with-hepatocellular-carcinoma-after-hepatectomy
#15
Yanhua Zhao, Shusheng Leng, Dongdong Li, Shu Feng, Zhonghao Wang, Chuanmin Tao
Tumor hypoxia can influence the progression and metastasis of various cancers, including hepatocellular carcinoma (HCC). Clinical studies have indicated that hyperbaric oxygen may improve the prognosis and reduce complications in HCC patients; however, whether pulmonary function can influence the prognosis of HCC remains unknown. In this study, we found that pulmonary function was associated with clinicopathological features, including smoking, liver cirrhosis, tumor size Edmondson-Steiner grade, total operative blood loss and perioperative blood transfusion...
September 26, 2017: Oncotarget
https://www.readbyqxmd.com/read/29031768/a-double-blind-randomized-trial-on-the-efficacy-and-safety-of-hyperbaric-oxygenation-therapy-in-the-preservation-of-erectile-function-after-radical-prostatectomy
#16
Kelly A Chiles, Ilene Staff, Kelly Johnson-Arbor, Alison Champagne, Tara McLaughlin, R James Graydon
PURPOSE: We evaluated the efficacy and safety of hyperbaric oxygenation therapy to preserve erectile function as part of penile rehabilitation after robot assisted bilateral nerve sparing radical prostatectomy for prostate cancer. MATERIALS AND METHODS: We performed a prospective, randomized, double-blind study from January 2009 to April 2013. Men 40 to 65 years old who underwent robot assisted bilateral nerve sparing radical prostatectomy were randomized 1:1 to the control or the treatment group...
October 13, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28924531/efficacy-of-metabolically-supported-chemotherapy-combined-with-ketogenic-diet-hyperthermia-and-hyperbaric-oxygen-therapy-for-stage-iv-triple-negative-breast-cancer
#17
Mehmet Salih İyikesici, Abdul Kadir Slocum, Ayshe Slocum, Ferhan Bulent Berkarda, Miriam Kalamian, Thomas N Seyfried
Triple-negative breast cancer (TNBC) is more aggressive and metastatic than other breast cancer types. Cytotoxic chemotherapy is presently the predominant systemic therapy for TNBC patients. This case report highlights the influence of metabolically supported chemotherapy (MSCT), ketogenic diet (KD), hyperthermia (HT), and hyperbaric oxygen therapy (HBOT) in an overweight 29-year-old woman with stage IV (T4N3M1) triple-negative invasive ductal carcinoma of the breast. The patient presented with an observable mass in her left breast detected during a physical examination in December 2015...
July 7, 2017: Curēus
https://www.readbyqxmd.com/read/28838774/the-role-of-hyperbaric-oxygen-therapy-in-the-prevention-and-management-of-radiation-induced-complications-of-the-head-and-neck-a-systematic-review-of-literature
#18
P Ravi, D Vaishnavi, A Gnanam, V B Krishnakumar Raja
Radiation therapy for the treatment of head and neck cancer can injure normal tissues and have devastating side effects. Hyperbaric oxygen (HBO) is known to reduce the severity of radiation-induced injury by promoting wound healing. While most of the research in literature has focused on its efficacy in osteonecrosis, HBO has other proven benefits as well. The aim of this review was to identify the various benefits of hyperbaric oxygen therapy in patients who have undergone radiation for head and neck cancer...
December 2017: Journal of Stomatology, Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28832662/oxygen-dependent-regulation-of-tumor-growth-and-metastasis-in-human-breast-cancer-xenografts
#19
Kristine Yttersian Sletta, Maria K Tveitarås, Ning Lu, Agnete S T Engelsen, Rolf K Reed, Annette Garmann-Johnsen, Linda Stuhr
BACKGROUND: Tumor hypoxia is relevant for tumor growth, metabolism, resistance to chemotherapy and metastasis. We have previously shown that hyperoxia, using hyperbaric oxygen treatment (HBOT), attenuates tumor growth and shifts the phenotype from mesenchymal to epithelial (MET) in the DMBA-induced mammary tumor model. This study describes the effect of HBOT on tumor growth, angiogenesis, chemotherapy efficacy and metastasis in a triple negative MDA-MB-231 breast cancer model, and evaluates tumor growth using a triple positive BT-474 breast cancer model...
2017: PloS One
https://www.readbyqxmd.com/read/28779583/use-of-indocyanine-green-fluorescent-angiography-in-a-hyperbaric-patient-with-soft-tissue-radiation-necrosis-a-case-report
#20
Kelly Johnson-Arbor, Reuben Falola, James Kelty, John Barbour, Christopher Attinger
INTRODUCTION: Indocyanine green fluorescent angiography (ICFA), commonly used to assess vascularity in patients with non-healing lower extremity wounds, is emerging as a useful adjunct for hyperbaric oxygen (HBO₂)therapy patients. We describe the use of ICFA to measure vascularity and help tailor an appropriate HBO₂ regimen in a patient with breast soft tissue radiation necrosis (STRN). CASE REPORT: 67-year-old female with a history of right breast cancer treated two years previously with lumpectomy and radiation therapy (6200 cGy), developed open wounds in the right breast...
May 2017: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
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