keyword
https://read.qxmd.com/read/38495319/parents-information-needs-during-the-first-year-at-home-with-their-very-premature-born-child-a-qualitative-study
#21
JOURNAL ARTICLE
Monique Flierman, Daniel Bossen, Rosa de Boer, Eline Vriend, Fenna van Nes, Anton van Kaam, Raoul Engelbert, Martine Jeukens-Visser
OBJECTIVE: To obtain insights into parents' information needs during the first year at home with their very preterm (VP) born infant. METHODS: We conducted semi-structured interviews with parents of VP infants participating in a post-discharge responsive parenting intervention (TOP program). Online interviews were audiotaped and transcribed verbatim. Inductive thematic analysis was performed by two independent coders. RESULTS: Ten participants were interviewed and had various and changing information needs during the developmental trajectory of their infant...
December 2024: PEC Innov
https://read.qxmd.com/read/38492741/-neurodevelopment-and-neuroprotection-in-young-children
#22
JOURNAL ARTICLE
Stéphane Marret, Alexandra Chadie, Jean-Baptiste Muller, Clément Chollat
In France, the most pessimistic estimates put the prevalence of neurodevelopmental disorders (NDD) at 15% of births. The two largest populations of newborns at highest risk of NDD are premature babies and babies born into siblings with one or more infants who already have an autism spectrum disorder or another NDD. The high prevalence of these disorders justifies a health promotion policy, centred on the child and his or her family. Prevention is based on the early identification of high-risk factors, by informing families and training pregnancy and early childhood professionals, and implementing perinatal prevention protocols for high-risk newborns (antenatal corticosteroid therapy and magnesium sulfate for women at risk of preterm delivery before 32 weeks, developmental care, therapeutic hypothermia for full-term infants with early neonatal encephalopathy presumed to be anoxic)...
March 14, 2024: Gynecologie, Obstetrique, Fertilite & Senologie
https://read.qxmd.com/read/38492032/ototoxic-and-nephrotoxic-drugs-in-neonatal-intensive-care-units-results-of-a-spanish-and-italian-survey
#23
JOURNAL ARTICLE
Cristina Arribas, Nunzia Decembrino, Genny Raffaeli, Ilaria Amodeo, Juan Luis González-Caballero, Mónica Riaza, Roberto Ortiz-Movilla, Luca Massenzi, Camilla Gizzi, Gabriella Araimo, Donatella Cattarelli, Salvatore Aversa, Stefano Martinelli, Simonetta Frezza, Luigi Orfeo, Fabio Mosca, Giacomo Cavallaro, Felipe Garrido
UNLABELLED: Neonates face heightened susceptibility to drug toxicity, often exposed to off-label medications with dosages extrapolated from adult or pediatric studies. Premature infants in Neonatal Intensive Care Units (NICUs) are particularly at risk due to underdeveloped pharmacokinetics and exposure to multiple drugs. The study aimed to survey commonly used medications with a higher risk of ototoxicity and nephrotoxicity in Spanish and Italian neonatal units. A prospective cross-sectional study was conducted in Italian and Spanish neonatal units using a web-based survey with 43 questions...
March 16, 2024: European Journal of Pediatrics
https://read.qxmd.com/read/38488791/pain-exposure-and-brain-connectivity-in-preterm-infants
#24
JOURNAL ARTICLE
Thiviya Selvanathan, Steven Ufkes, Ting Guo, Vann Chau, Helen M Branson, George M Ibrahim, Linh G Ly, Edmond N Kelly, Ruth E Grunau, Steven P Miller
IMPORTANCE: Early-life exposure to painful procedures has been associated with altered brain maturation and neurodevelopmental outcomes in preterm infants, although sex-specific differences are largely unknown. OBJECTIVE: To examine sex-specific associations among early-life pain exposure, alterations in neonatal structural connectivity, and 18-month neurodevelopment in preterm infants. DESIGN, SETTING, AND PARTICIPANTS: This prospective cohort study recruited 193 very preterm infants from April 1, 2015, to April 1, 2019, across 2 tertiary neonatal intensive care units in Toronto, Canada...
March 4, 2024: JAMA Network Open
https://read.qxmd.com/read/38488714/perfusion-techniques-for-an-800%C3%A2-g-premature-neonate-undergoing-arterial-switch-procedure-for-transposition-of-the-great-arteries%C3%A2
#25
Richard Owens, Madeline Loftin, Kellen Rosten, Douglas Fisher, Blake Denison, Erin Gottlieb, Charles Fraser
Early cardiac surgery in neonates and infants with congenital heart disease has been performed since the middle to late years of the twentieth century. To date, there are very few reports of successful congenital heart surgery using cardiopulmonary bypass (CPB) in premature babies less than 1000 g with serious congenital heart disease. Limited information is available in the literature describing perfusion techniques for this extremely fragile patient population. Miniaturization of the CPB circuit contributes to multiple factors that affect this population significantly...
March 2024: Journal of Extra-corporeal Technology
https://read.qxmd.com/read/38487471/contemporary-fluid-management-humidity-and-patent-ductus-arteriosus-management-strategy-for-premature-infants-among-336-hospitals-in-asia
#26
JOURNAL ARTICLE
Yao-Chi Hsieh, Mei-Jy Jeng, Ming-Chih Lin, Yuh-Jyh Lin, Rinawati Rohsiswatmo, Rizalya Dewi, Seok Chiong Chee, Siew Hong Neoh, Belen Amparo E Velasco, Ma Lourdes S Imperial, Pracha Nuntnarumit, Sopapan Ngerncham, Yun Sil Chang, Sae Yun Kim, Bin Huey Quek, Zubair Amin, Satoshi Kusuda, Fuyu Miyake, Tetsuya Isayama
OBJECTIVES: The management of patent ductus arteriosus (PDA) is a critical concern in premature infants, and different hospitals may have varying treatment policies, fluid management strategies, and incubator humidity. The Asian Neonatal Network Collaboration (AsianNeo) collected data on prematurity care details from hospitals across Asian countries. The aim of this study was to provide a survey of the current practices in the management of PDA in premature infants in Asian countries...
2024: Frontiers in Pediatrics
https://read.qxmd.com/read/38487157/perinatal-birth-asphyxia-among-newborns-at-jiblah-public-health-hospital-in-ibb-city-yemen-during-six-years-of-conflict-and-its-predictive-factors-a-retrospective-cross-sectional-study
#27
JOURNAL ARTICLE
Afaf Alsharif, Abdullah M Almatary, Faisal Ahmed, Mohamed Badheeb
BACKGROUND: Birth asphyxia is a major cause of infant death across the world, especially in developing countries, where the issue is significantly underreported and underestimated, particularly in fragile and conflict-affected states. OBJECTIVE: The purpose of this study was to determine the prevalence and risk factors for birth asphyxia in women at Jiblah University Hospital in Ibb, Yemen, and its predictive factors throughout six years of conflict. METHOD: We conducted a retrospective cross-sectional chart review and analysis of the birth database spanning from June 2013 to September 2019 at Jiblah University Hospital in Ibb, Yemen...
February 2024: Curēus
https://read.qxmd.com/read/38486338/effectiveness-of-extracellular-vesicles-derived-from-hipscs-in-repairing-hyperoxia-induced-injury-in-a-fetal-murine-lung-explant-model
#28
JOURNAL ARTICLE
Hala Saneh, Heather Wanczyk, Joanne Walker, Christine Finck
BACKGROUND: Despite advances in neonatal care, the incidence of Bronchopulmonary Dysplasia (BPD) remains high among preterm infants. Human induced pluripotent stem cells (hiPSCs) have shown promise in repairing injury in animal BPD models. Evidence suggests they exert their effects via paracrine mechanisms. We aim herein to assess the effectiveness of extracellular vesicles (EVs) derived from hiPSCs and their alveolar progenies (diPSCs) in attenuating hyperoxic injury in a preterm lung explant model...
March 14, 2024: Stem Cell Research & Therapy
https://read.qxmd.com/read/38476092/cdc-s-new-hepatitis-c-virus-testing-recommendations-for-perinatally-exposed-infants-and-children-a-step-towards-hepatitis-c-elimination
#29
JOURNAL ARTICLE
Lakshmi Panagiotakopoulos, Kathryn Miele, Emily J Cartwright, Saleem Kamili, Nathan Furukawa, Kate Woodworth, Van T Tong, Shin Y Kim, Carolyn Wester, Amy L Sandul
New U.S. Centers for Disease Control and Prevention (CDC) guidelines for hepatitis C virus (HCV) testing of perinatally exposed infants and children released in 2023 recommend a nucleic acid test (NAT) for detection of HCV ribonucleic acid ( i.e. , NAT for HCV RNA) at 2-6 months of age to facilitate early identification and linkage to care for children with perinatally acquired HCV infection. Untreated hepatitis C can lead to cirrhosis, liver cancer, and premature death and is caused by HCV, a blood-borne virus transmitted most often among adults through injection drug use in the United States...
March 13, 2024: Journal of Women's Health
https://read.qxmd.com/read/38474729/bioelectrical-impedance-in-premature-newborns-and-its-relationship-with-diet-therapy-in-a-neonatal-intensive-care-unit
#30
JOURNAL ARTICLE
Catiuscie Cabreira da Silva Tortorella, Bárbara Mendes Paz Chao, Estela Iraci Rabito, Mônica Nunes Lima, Ana Lúcia Figueiredo Sarquis
(1) Background: To estimate resistance, reactance, and phase angle values among moderate preterm infants and their variation according to neonatal and maternal characteristics and nutritional intake. (2) Methods: This was a cohort that evaluated 43 moderate preterm infants using bioelectrical impedance analysis. The study variables included resistance, reactance, and phase angle measurements, in addition to classification of nutritional intake. (3) Results: Mean resistance was 602.0 ± 118.2 Ω, reactance was 57...
February 22, 2024: Nutrients
https://read.qxmd.com/read/38474125/a-review-of-the-use-of-extracellular-vesicles-in-the-treatment-of-neonatal-diseases-current-state-and-problems-with-translation-to-the-clinic
#31
REVIEW
Kirill Goryunov, Mikhail Ivanov, Andrey Kulikov, Yulia Shevtsova, Artem Burov, Yulia Podurovskaya, Victor Zubkov, Dmitry Degtyarev, Gennady Sukhikh, Denis Silachev
Neonatal disorders, particularly those resulting from prematurity, pose a major challenge in health care and have a significant impact on infant mortality and long-term child health. The limitations of current therapeutic strategies emphasize the need for innovative treatments. New cell-free technologies utilizing extracellular vesicles (EVs) offer a compelling opportunity for neonatal therapy by harnessing the inherent regenerative capabilities of EVs. These nanoscale particles, secreted by a variety of organisms including animals, bacteria, fungi and plants, contain a repertoire of bioactive molecules with therapeutic potential...
March 1, 2024: International Journal of Molecular Sciences
https://read.qxmd.com/read/38472762/monitoring-the-use-of-human-milk-the-ideal-food-for-very-low-birth-weight-infants-a-narrative-review
#32
REVIEW
Pasqua Anna Quitadamo, Federica Zambianco, Giuseppina Palumbo, Xavier Wagner, Maria Assunta Gentile, Antonio Mondelli
Aware of the utmost importance of feeding premature babies-especially those of lower weight-with human milk, as well as the need to monitor this important element of neonatal care, we focused on four aspects in this review. First of all, we reviewed the beneficial effects of feeding premature infants with breast milk in the short and long term. Secondly, we performed a quantitative evaluation of the rates of breastfeeding and feeding with human milk in Very-Low-Birth-Weight infants (VLBWs) during hospitalization in the Neonatal Intensive Care Unit (NICU) and at discharge...
February 21, 2024: Foods (Basel, Switzerland)
https://read.qxmd.com/read/38471804/relevance-and-antimicrobial-resistance-profile-of-klebsiella-pneumoniae-in-neonatal-sepsis
#33
JOURNAL ARTICLE
Hui Ma, JingWen Xu, YanHong Zhang, RenYan Zhang, Jie Wu
BACKGROUND: Newborns are particularly susceptible to infection in hospitals, with neonatal sepsis being the most common infection symptom and the third leading cause of neonatal death. Klebsiella pneumoniae is a gram-negative bacterium of Enterobacteriaceae, which is a common pathogen of neonatal septicemia. In this study, we will analyze and evaluate the current status, clinical characteristics, and drug resistance of Klebsiella pneumoniae sepsis infection in Neonatal Intensive Care Unit (NICU), with the aim of providing effective basis for timely and accurate clinical diagnosis and treatment in clinical practice...
December 2024: Journal of Maternal-fetal & Neonatal Medicine
https://read.qxmd.com/read/38467704/new-insights-and-potential-biomarkers-for-intraventricular-hemorrhage-in-extremely-premature-infant-case-control-study
#34
JOURNAL ARTICLE
Franklin Ducatez, Abdellah Tebani, Lenaig Abily-Donval, Sarah Snanoudj, Carine Pilon, Thomas Plichet, Charlotte Le Chatelier, Soumeya Bekri, Stéphane Marret
BACKGROUND: Despite advancements in neonatal care, germinal matrix-intraventricular hemorrhage impacts 20% of very preterm infants, exacerbating their neurological prognosis. Understanding its complex, multifactorial pathophysiology and rapid onset remains challenging. This study aims to link specific cord blood biomolecules at birth with post-natal germinal matrix-intraventricular hemorrhage onset. METHODS: A monocentric, prospective case-control study was conducted at Rouen University Hospital from 2015 to 2020...
March 11, 2024: Pediatric Research
https://read.qxmd.com/read/38467152/-who-recommendations-for-care-of-the-preterm-or-low-birth-weight-infant
#35
JOURNAL ARTICLE
Dominic Ledinger, Barbara Nußbaumer-Streit, Gerald Gartlehner
BACKGROUND: Premature infants (gestation age<37 weeks) and low-birth-weight infants (< 2.5 kg) require complex care to ensure their survival, growth and neurological development. Increased risk for developmental disorders, infections, and challenges with nutrition and body temperature regulation require comprehensive measures in care. AIM: The aim of this guideline was to improve the care of premature and low-birth-weight infants through updated recommendations...
March 11, 2024: Das Gesundheitswesen
https://read.qxmd.com/read/38464682/alleviating-neonatal-intensive-care-unit-stress-a-chinese-medicine-approach-in-neonatal-rats
#36
JOURNAL ARTICLE
Yingxin Li, Xi Huang, Yanlin Hu, Liming Yang, Xiujuan Zhang, Qiong Chen
BACKGROUND: Premature infants are exposed to numerous stressors in neonatal intensive care unit (NICU) during a crucial period for brain development; this period exerts long-term influences on cognitive and behavioral development. AIMS: To evaluate the effect of NICU-related stress on neonatal rat pups and explore the effect of Chinese medicine treatment (CMT). METHODS: Sixty male rat pups were randomly assigned to three groups: the control group, the NICU group (NICU-related stress), and the CMT group (NICU-related stress plus CMT)...
2024: BioMed Research International
https://read.qxmd.com/read/38463430/associations-between-prematurity-postpartum-anxiety-neonatal-intensive-care-unit-admission-and-stress
#37
JOURNAL ARTICLE
Semra Worrall, Paul Christiansen, Asma Khalil, Sergio A Silverio, Victoria Fallon
INTRODUCTION: It is well established that a premature birth increases the likelihood of developing anxiety during the postpartum period, and that the environment of the neonatal intensive care unit (NICU) might be a contributing factor. Mothers of earlier premature infants may experience these anxieties to a higher degree compared to mothers of later premature infants. The aim of this study was to explore the association between prematurity and postpartum-specific anxiety, and the relationship between postpartum-specific anxiety and stress in the NICU...
2024: Frontiers in Psychiatry
https://read.qxmd.com/read/38457157/the-association-of-micrornas-in-the-development-of-retinopathy-of-prematurity
#38
JOURNAL ARTICLE
F Ovali, M Hakbilen, I Akalin, G Çelik, S Yildirim
INTRODUCTION: Retinopathy of prematurity (ROP) is one of the main reasons of preventable childhood blindness. In the development of ROP, MicroRNAs may be effective in the balance of factors that inhibit and activate angiogenic factors. We aimed to determine the changes in the blood levels of miR-146a, miR-143, miR-210, miR-21, miR-126, miR-211, miR-221, miR-106 and let 7f and to investigate their association with ROP. We hypothesed that the level of these miRNAs changed significantly in ROP cases...
2024: Journal of Neonatal-perinatal Medicine
https://read.qxmd.com/read/38456989/risk-factors-for-infant-hearing-loss-a-meta-analysis
#39
JOURNAL ARTICLE
Yiwei Han, Shangbin Li, Yankun Song, Jingfei Sun, Weichen Yan, Jie Wang, Xiong Gao, Xueying Li, Changjun Ren, Qian Zhao
Hearing loss is a common disability in infants that significantly impacts their cognitive, language, and literacy development. This study aimed to systematically assess the risk factors for the early identification and intervention in infant hearing loss. Databases were searched for meta-analyses of observational studies until November 2023. The quality assessment was performed using the Cochrane risk of bias tool, and the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach was used to assess the certainty of the evidence...
March 8, 2024: European Journal of Pediatrics
https://read.qxmd.com/read/38455809/exploring-risk-factors-and-perinatal-outcomes-of-preterm-birth-in-a-tertiary-care-hospital-a-comprehensive-analysis
#40
JOURNAL ARTICLE
Ritika Agarwal, Rajni Agrawal
Background Preterm birth before 37 weeks of gestation is a global public health challenge, particularly in India, where the prevalence varies regionally. Understanding risk factors, such as maternal age and complications like hypertensive disorders, is vital. India's diverse healthcare landscape and regional disparities further complicate this issue. Preterm infants face increased mortality and morbidity risks like respiratory distress and intraventricular hemorrhage. This study in a tertiary care hospital aimed to analyze risk factors, assess perinatal outcomes, and contribute to the understanding of preterm birth in this complex context, providing valuable insights for maternal and child health strategies...
February 2024: Curēus
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