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Premature infant care

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https://www.readbyqxmd.com/read/29684832/effect-of-non-nutritive-sucking-and-sucrose-alone-and-in-combination-for-repeated-procedural-pain-in-preterm-infants-a-randomized-controlled-trial
#1
Haixia Gao, Mei Li, Honglian Gao, Guihua Xu, Fang Li, Jing Zhou, Yunsu Zou, Honghua Jiang
BACKGROUND: Sucrose combined with non-nutritive sucking provided better pain relief than sucrose or non-nutritive sucking alone in a single painful procedure. However, whether the combination of non-nutritive sucking with sucrose could obtain a significant difference in analgesic effect of the repeated procedural pain than any single intervention has not been established. OBJECTIVE: To compare the effect of non-nutritive sucking and sucrose alone and in combination of repeated procedural pain in preterm infants...
April 7, 2018: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/29679617/retinopathy-of-prematurity-a-review-of-risk-factors-and-their-clinical-significance
#2
REVIEW
Sang Jin Kim, Alexander D Port, Ryan Swan, J Peter Campbell, R V Paul Chan, Michael F Chiang
Retinopathy of prematurity (ROP) is a retinal vasoproliferative disease that affects premature infants. Despite improvements in neonatal care and management guidelines, ROP remains a leading cause of childhood blindness worldwide. Current screening guidelines are primarily based on two risk factors: birth weight and gestational age; however, many investigators have suggested other risk factors, including maternal factors, prenatal and perinatal factors, demographics, medical interventions, comorbidities of prematurity, nutrition, and genetic factors...
April 19, 2018: Survey of Ophthalmology
https://www.readbyqxmd.com/read/29679047/a-quality-improvement-initiative-to-reduce-necrotizing-enterocolitis-across-hospital-systems
#3
Amy T Nathan, Laura Ward, Kurt Schibler, Laurel Moyer, Andrew South, Heather C Kaplan
OBJECTIVE: Necrotizing enterocolitis (NEC) is a devastating intestinal disease in premature infants. Local rates of NEC were unacceptably high. We hypothesized that utilizing quality improvement methodology to standardize care and apply evidence-based practices would reduce our rate of NEC. STUDY DESIGN: A multidisciplinary team used the model for improvement to prioritize interventions. Three neonatal intensive care units (NICUs) developed a standardized feeding protocol for very low birth weight (VLBW) infants, and employed strategies to increase the use of human milk, maximize intestinal perfusion, and promote a healthy microbiome...
April 20, 2018: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/29679046/impact-of-antenatal-corticosteroids-in-preterm-neonates-based-on-maternal-body-mass-index
#4
Maheer Faden, Sarah D McDonald, Prakeshkumar S Shah, Amit Mukerji
OBJECTIVE: Impact of antenatal corticosteroid (ACS) in context of maternal body mass index (BMI) as it relates to neonatal outcomes remains unclear. We sought to evaluate effects of ACS on clinical outcomes of preterm infants based on maternal BMI. METHODS: We performed a retrospective cohort study among neonates 23-33 weeks' GA at a tertiary neonatal intensive care unit from 2011 to 2015. Outcomes of neonates exposed to any ACS and pre-pregnancy maternal BMI ≥ 25 (N = 491) were compared with maternal BMI < 25 (N = 484)...
April 20, 2018: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/29676033/fio-2-control-by-parents-of-preterm-infants-admitted-to-a-neonatal-intensive-care-unit-a-pilot-study
#5
M D Martín-Pelegrina, A Lorenzo-Rodríguez, D Lora-Pablos, B Muñóz-Amat, C Morales-Betancourt, C R Pallás-Alonso
When newborns are admitted to the neonatal intensive care unit for prematurity or other reasons, parents do not take on the role that they were expecting to assume. That is, they do not become the main caregivers of their children. To address this issue, neonatal units are currently trying to involve parents in the care of their children as soon as possible. Interesting experiences regarding this issue have been published. Most of the experiences show that when parents assume part of the responsibility for caring for their children, breastfeeding is prolonged, hospital-stay lengths decrease, weight gain increases and the numbers of readmissions decrease (1-4)...
April 19, 2018: Acta Paediatrica
https://www.readbyqxmd.com/read/29673564/factors-affecting-the-efficacy-and-safety-of-aminophylline-in-treatment-of-apnea-of-prematurity-in-neonatal-intensive-care-unit
#6
Chaohui Ye, Caiyun Miao, Li Yu, Zhuoya Dong, Jie Zhang, Yingying Mao, Xiaodong Lu, Qin Lyu
BACKGROUND: The factors affecting the safety and efficacy of aminophylline use in the treatment of apnea of prematurity (AOP) in the neonatal intensive care unit (NICU) are not clear. In this study, we aimed to evaluate the potential factors affecting the efficacy and safety of aminophylline in AOP treatment at standard doses and to determine appropriate patients for this therapy. METHODS: Over a 3-year period (January 2012 to December 2014), the medical records of 206 preterm infants with apnea who were admitted to the NICU of our hospital to receive aminophylline infusions were retrospectively reviewed...
March 30, 2018: Pediatrics and Neonatology
https://www.readbyqxmd.com/read/29669357/oxygenation-of-the-immature-infant-a-commentary-and-recommendations-for-oxygen-saturation-targets-and-alarm-limits
#7
Ola Didrik Saugstad
BACKGROUND: For 70 years, there has been a search for the optimal oxygenation of premature infants. In spite of the lack of evidence, guidelines have successively reduced oxygenation targets during these years. OBJECTIVES: (1) To present a summary of previously published meta-analyses of 5 randomized studies (NeOProM) which tested a low (85-89%) versus a high (91-95%) oxygen saturation target the first weeks after birth on outcome of immature newborn infants. (2) To present international recommendations for oxygenation the first weeks after birth...
April 18, 2018: Neonatology
https://www.readbyqxmd.com/read/29668967/reducing-blindness-from-retinopathy-of-prematurity-rop-in-argentina-through-collaboration-advocacy-and-policy-implementation
#8
Luxme Hariharan, Clare E Gilbert, Graham E Quinn, Frances K Barg, Celia Lomuto, Ana Quiroga, Joan McLeod-Omawale, Andrea Zin, Zulma Ortiz, Ernesto Alda, Liliana Bouzas, Marina Brussa, Adriana Cattaino, Alejandro Dinerstein, Norma Erpen, Adriana Fandiño, Lidia Galina, Julio Manzitti, Silvia Marinaro, Teresa Sepúlveda, Patricia Visintín, Juan Carlos Silva, Cynthia Magluta, Alicia Benitez
Retinopathy of prematurity (ROP) is a largely avoidable cause of blindness in children worldwide, requiring high-quality neonatal care, early detection and treatment. In middle-income countries throughout Latin America, Eastern Europe and South Asia, there has been a rise in ROP blindness due to a combination of increased survival of preterm infants, resource-scarce medical environments and lack of policies, training and human resources. However, Argentina is an example of country where rates of ROP blindness have declined and ROP programmes have been successfully and effectively embedded within the health and legal system...
April 16, 2018: Health Policy and Planning
https://www.readbyqxmd.com/read/29667359/predicting-responses-to-mechanical-ventilation-for-preterm-infants-with-acute-respiratory-illness-using-artificial-neural-networks
#9
Katharine Brigham, Samir Gupta, John C Brigham
Infants born prematurely are particularly susceptible to respiratory illness due to underdeveloped lungs, which can often result in fatality. Preterm infants in acute stages of respiratory illness typically require mechanical ventilation assistance, and the efficacy of the type of mechanical ventilation and its delivery has been the subject of a number clinical studies. With recent advances in machine learning approaches, particularly deep learning, it may be possible to estimate future responses to mechanical ventilation in real-time, based on ventilation monitoring up to the point of analysis...
April 17, 2018: International Journal for Numerical Methods in Biomedical Engineering
https://www.readbyqxmd.com/read/29664051/predictive-value-of-cranial-ultrasound-for-neurodevelopmental-outcomes-of-very-preterm-infants-with-brain-injury
#10
Xue-Hua Zhang, Shi-Jun Qiu, Wen-Juan Chen, Xi-Rong Gao, Ya Li, Jing Cao, Jing-Jing Zhang
Background: Compared with full-term infants, very preterm infants are more vulnerable to injury and long-term disability and are at high risk of death. The predictive value of ultrasound and imaging on the neurodevelopment is one of the hot topics. This study aimed to investigate the relationship between cranial ultrasound (cUS) variables and neurodevelopmental outcomes of very preterm infants. Methods: Totally 129 very preterm infants (gestational age ≤28 weeks) in neonatal intensive care unit of Hunan Children's Hospital between January 2012 and November 2014 were included in this retrospective study...
April 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29660756/use-of-palivizumab-in-germany-report-from-the-german-synagis%C3%A2-registry-2009-2016
#11
Arne Simon, Susanne Gehrmann, Gudrun Wagenpfeil, Stefan Wagenpfeil
BACKGROUND: Following national recommendations, palivizumab is administered in Germany to high-risk infants to prevent hospitalizations related to Respiratory Syncytial Virus infection. METHODS: In this post marketing observational study (German SYNAGIS™ Registry) data on risk factors and the clinical course of children, who received at least one palivizumab injection between 2009-2016 (01 September to June 30) were entered into an internet-based data entry system by the attending physicians after informed consent...
April 16, 2018: Klinische Pädiatrie
https://www.readbyqxmd.com/read/29649028/does-the-incidence-of-postoperative-complications-after-inguinal-hernia-repair-justify-hospital-admission-in-prematurely-and-term-born-infants
#12
Marina Massoud, A Y Rosalie Kühlmann, Monique van Dijk, Lonneke M Staals, Rene M H Wijnen, Joost van Rosmalen, Cornelius E J Sloots, Claudia M G Keyzer-Dekker
BACKGROUND: Postoperatively, young infants are admitted overnight in view of the risk for respiratory complications such as desaturation and apnea. This risk seems much lower than previously reported. Until what age this risk persists, and which infants might actually qualify for day-care treatment, is unknown. METHODS: We retrospectively reviewed medical charts from preterm infants <45 weeks postconceptional age (PCA), 45-60 weeks PCA, and term infants <3 months admitted overnight after inguinal hernia repair, from January 2011 to December 2015 in a large tertiary children's hospital...
April 11, 2018: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29625857/decrease-of-premature-mothers-stress-levels-in-the-intensive-care-unit
#13
B Villamizar-Carvajal, C Vargas-Porras, J R García-Corzo
OBJECTIVE: To determine the effectiveness of the 'Creating Opportunities for Parent Empowerment' (COPE) programme in reducing stress levels in mothers of preterm infants in the neonatal intensive care unit (NICU). METHODS: Clinical trial performed in Colombia, including mothers of infants younger than 34 weeks of gestation, hospitalized, without a history of premature delivery. The mothers with psychiatric illnesses, language disorders, history of use of psychoactive substances and whose newborns had a congenital malformation were excluded...
April 3, 2018: Enfermería Intensiva
https://www.readbyqxmd.com/read/29621770/identifying-risk-factors-shared-by-bronchopulmonary-dysplasia-severe-retinopathy-and-cystic-periventricular-leukomalacia-in-very-preterm-infants-for-targeted-intervention
#14
Lan-Wan Wang, Yung-Chieh Lin, Shan-Tair Wang, Chao-Ching Huang
BACKGROUND: Bronchopulmonary dysplasia (BPD), severe retinopathy of prematurity (sROP), and cystic periventricular leukomalacia (cPVL) are 3 major morbidities with long-term neurodevelopmental impairments in preterm infants. OBJECTIVE: To investigate the strength of associations and identify key risk factors shared by BPD, sROP, and cPVL for targeted intervention. METHODS: We studied the Taiwanese very-preterm-infant registry data on 3,507 infants admitted to neonatal intensive care units and discharged at postmenstrual age ≥36 weeks between 2008 and 2013...
April 5, 2018: Neonatology
https://www.readbyqxmd.com/read/29621506/parents-knowledge-and-education-of-retinopathy-of-prematurity-in-four-california-neonatal-intensive-care-units
#15
Monica Eneriz-Wiemer, Shih-Dun Liu, Michael Cy Chu, Tarsicio Uribe-Leitz, Krishna Rajani, Meera Sankar, Shira L Robbins, Henry C Lee, Claire Woodard, C Jason Wang
PURPOSE: Retinopathy of prematurity (ROP) may cause visual impairment in infants with very low birth weight. Lack of parent knowledge may contribute to gaps in screening and treatment. We studied parents' knowledge and education of ROP. DESIGN: Cross-sectional study. METHODS: SETTING: Four high-acuity neonatal intensive care units in California (40-84 beds). PARTICIPANTS: 194 English- and Spanish-speaking parents of very low birth weight (<1,500 grams) infants recruited from September 2013 to April 2015...
April 2, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29621387/diagnostic-accuracy-of-ophthalmoscopy-vs-telemedicine-in-examinations-for-retinopathy-of-prematurity
#16
Hilal Biten, Travis K Redd, Chace Moleta, J Peter Campbell, Susan Ostmo, Karyn Jonas, R V Paul Chan, Michael F Chiang
Importance: Examinations for retinopathy of prematurity (ROP) are typically performed using binocular indirect ophthalmoscopy. Telemedicine studies have traditionally assessed the accuracy of telemedicine compared with ophthalmoscopy as a criterion standard. However, it is not known whether ophthalmoscopy is truly more accurate than telemedicine. Objective: To directly compare the accuracy and sensitivity of ophthalmoscopy vs telemedicine in diagnosing ROP using a consensus reference standard...
April 5, 2018: JAMA Ophthalmology
https://www.readbyqxmd.com/read/29621379/fluorescein-angiographic-characteristics-of-macular-edema-during-infancy
#17
Xi Chen, Shwetha Mangalesh, Du Tran-Viet, Sharon F Freedman, Lejla Vajzovic, Cynthia A Toth
Importance: Macular edema during infancy, a subclinical feature identified in premature infants by handheld spectral-domain optical coherence tomography (SD-OCT), has been associated with poorer visual acuity and neurodevelopmental outcomes. Features of macular edema on fluorescein angiography (FA) are needed to understand its pathophysiology, but to date have not been reported previously. Objective: To investigate the FA features of macular edema during infancy...
April 5, 2018: JAMA Ophthalmology
https://www.readbyqxmd.com/read/29613975/antibiotic-overuse-in-premature-low-birth-weight-infants-in-a-developing-country
#18
Maria S Rueda, Renzo Calderon-Anyosa, Jorge Gonzales, Christie G Turin, Alonso Zea-Vera, Jaime Zegarra, Sicilia Bellomo, Luis Cam, Anne Castaneda, Theresa J Ochoa
BACKGROUND: Neonatal sepsis is a leading cause of child morbidity and mortality, especially in premature and low-birth-weight (LBW) infants. Prompt antibiotic therapy is warranted, but its inappropriate use leads to bacterial resistance and adverse outcomes. Our objective is to describe the antibiotic use for late onset sepsis (LOS) in Peruvian premature infants. METHODS: Prospective study as a secondary analysis of a clinical trial in three Neonatal Care Units in Peru...
April 2, 2018: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29603412/improving-nutrition-outcomes-for-infants-1500-grams-with-a-progressive-evidenced-based-enteral-feeding-protocol
#19
Melissa K Thoene, Elizabeth Lyden, Ann Anderson-Berry
BACKGROUND: Growth is essential for very low birth weight infants. The purpose of this retrospective chart review was to evaluate the impact of a new standardized, evidenced-based feeding protocol for infants born < 1500 g in correlation with growth and clinical outcomes. METHODS: Growth and nutrition data was reviewed from 2 groups of infants born < 1500 g within a level III newborn intensive care unit (NICU). Epoch 1 infants (N = 32) received care following initial implementation of a standardized enteral feeding protocol...
March 30, 2018: Nutrition in Clinical Practice
https://www.readbyqxmd.com/read/29602579/continued-uncertainty-regarding-treatment-of-patent-ductus-arteriosus-in-premature-infants-and-the-role-of-clinical-trials
#20
REVIEW
Edmund Juszczak, Samir Gupta
Despite several decades of research into treatments for patent ductus arteriosus (PDA), there is continued uncertainty regarding whether, when, and how best to treat PDA and the long-term consequences. There are almost 5000 babies enrolled into clinical trials, but the questions remain largely unanswered. Many of the trials performed over the period were well designed and addressed important clinical questions, but the results are not necessarily directly applicable to the clinical management dilemmas of today since perinatal care has improved over time per se, the patient population is typically more premature, and there have been technological advances in diagnosis...
March 7, 2018: Seminars in Fetal & Neonatal Medicine
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