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V I Konenkov, L N Rachkovskaya, A Yu Letyagin, N I Suslov, A V Shurlygina, M V Robinson, M A Korolev, A A Kotlyarova, T V Popova, E E Rachkovskii, T N Povet'eva, N V Shilova, Yu V Nesterova, O G Afanas'eva, P V Kul'pin
The study examined the effects of a novel neurotropic medication based on a lithium complex composed of lithium citrate, polymethylsiloxane, and aluminum oxide on electrophysiological parameters of the rat brain. In contrast to lithium carbonate (the reference drug), the novel preparation resulted in a wave-like dynamics of electrical activity in the visual cortex. Rhythmic photic stimulation of the rats treated with lithium carbonate resulted in appearance of the signs attesting to up-regulation of excitability of cerebral cortex in all examined ranges...
August 18, 2018: Bulletin of Experimental Biology and Medicine
Marina Carbone, Vincenzo Ferrari, Michele Marconi, Roberta Piazza, Andrea Del Corso, Daniele Adami, Quintilia Lucchesi, Valeria Pagni, Raffaella Berchiolli
In non-urban scenarios: rural areas or small cities, there is often a limited access to specialistic healthcare due to the inherent challenges associated with recruitment, retention, and access to healthcare professionals. Telemedicine is an economical and effective way to address this problem. In this research, we developed a framework for real-time communication during ultrasound examination that combines interaction via standard video conference protocols and basic AR functionalities (commercial) and a custom-developed application...
August 18, 2018: Updates in Surgery
Linan Liu, Lihua Wang, Wenhong Song, Liang Yang, Liming Yin, Shaopan Xia, Hailong Wang, Peter James Strong, Zhaoliang Song
Fruit shell residue from Xanthoceras sorbifolia was investigated as a potential biosorbent to remove crude oil from aqueous solution. The shell powder and its carbonized material were compared while assessing various factors that influenced oil removal capacity. The structure and sorption mechanism were characterized using scanning electron microscopy and Fourier-transform infrared spectroscopy. The oil removal capacity of the raw material (75.1 mg g-1 ) was better than the carbonized material (49.5 mg g-1 )...
August 18, 2018: Environmental Science and Pollution Research International
Soo-Jung Kim, Jung-Eun Lee, Do Yup Lee, Haeseong Park, Kyoung Heon Kim, Yong-Cheol Park
In this study, an evolved Saccharomyces cerevisiae HJ7-14 with high ability of algae-based ethanol production was characterized by multi-omic approaches. Genome sequencing of the HJ7-14 revealed a point mutation in the GAL83 gene (G703A) involved in the catabolite repression as well as the galactose metabolism. Cultural and transcriptional analyses of a S. cerevisiae mutant with chromosomal GAL83(G703A) indicated that the catabolite repression onto the galactose metabolism was considerably relieved in all cell growth stages...
August 18, 2018: Applied Microbiology and Biotechnology
Guillaume Mabilleau, Benoit Gobron, Aleksandra Mieczkowska, Rodolphe Perrot, Daniel Chappard
Glucose-dependent insulinotropic polypeptide (GIP) has been recognized in the last decade as an important contributor of bone remodeling and is necessary for optimal bone quality. However, GIP receptors are expressed in several tissues in the body and little is known about the direct versus indirect effects of GIP on bone remodeling and quality. The aims of the present study were to validate two new GIP analogues, called [D-Ala2]-GIP-Tag and [D-Ala2]-GIP1-30, that specifically target either bone or whole body GIP receptors, respectively; and to ascertain the beneficial effects of GIP therapy on bone in a mouse model of ovariectomy-induced bone loss...
August 18, 2018: Journal of Endocrinology
A Cabrera-Reina, S Miralles-Cuevas, G Rivas, J A Sánchez Pérez
This paper represents a first approach in the study of photoreactor selection to treat industrial wastewater using solar photo-Fenton. In this context, simulated textile industry effluent containing a mixture of four dyes at different initial dissolved organic carbon (DOC) concentrations (45, 90, 180 and 270 mg/L) was treated by using three different solar reactor geometries: (i) tubular (5 cm diameter) provided with compound parabolic collector (ii) tubular (5 cm diameter) provided with flat collector and (iii) open channels forming raceway ponds with two liquid depths (5 and 15 cm)...
August 15, 2018: Science of the Total Environment
Lotfi Aleya, Elise Grisey, Mohamed Bourioug, Pascale Bourgeade
This study examined the lagooning treatment system of the Etueffont landfill (France) over a period of 16 years. Outflow concentrations in total suspended solids, biological oxygen demand (BOD5 ) and trace metal elements largely met outflow standards and were on average of 5, 8 and 6 times lower than those observed at inflow, respectively. In 2000, however, high levels of BOD5 were observed in both the influent and effluent, exceeding the authorized outflow limits. At that time the lagooning ponds were subjected temporarily to organic pollution, coinciding with the arrival of the first leachates from a new cell...
August 15, 2018: Science of the Total Environment
Rong Chen, Zhigang Chen, Mengxia Ji, Hanxiang Chen, Yiling Liu, Jiexiang Xia, Huaming Li
Novel Carbon quantum dots modified Bi5 O7 I (CQDs/Bi5 O7 I) nanorod composites were prepared via an ionic liquid 1-ethyl-3-methylimidazolium iodide ([Emim]I) assisted solvothermal method for the first time. Series of characterization methods were used to explore the structural composition, morphology and optical properties of as-prepared CQDs/Bi5 O7 I photocatalysts. Compared with pure Bi5 O7 I nanorod, CQDs/Bi5 O7 I composites exhibited the increased the specific surface area and visible light capture capability so as to expose more active sites and make full use of sunlight...
July 12, 2018: Journal of Colloid and Interface Science
Darren J Koppel, Merrin S Adams, Catherine K King, Dianne F Jolley
Metal contaminants are rarely present in the environment individually, yet environmental quality guidelines are derived from single-metal toxicity data. Few metal mixture studies have investigated more than binary mixtures and many are at unrealistically high effect concentrations to freshwater organisms. This study investigates the toxicity of five metals (Cd, Cu, Ni, Pb, and Zn) to the Antarctic marine microalgae Phaeocystis antarctica and Cryothecomonas armigera. Two mixtures were tested: (i) an equitoxic mixture of contaminants present at their single-metal EC10 concentrations, and (ii) an environmental mixture based on the ratio metal concentrations in a contaminated Antarctic marine bay...
July 25, 2018: Environmental Pollution
Qian Xiang, Guoqiang Shan, Wei Wu, Hangbiao Jin, Lingyan Zhu
Accurate measuring n-octanol/water partition coefficients (log Kow ) of perfluoroalkyl carboxylic acids (PFCAs) using experimental approach has been proven to be very difficult due to their special properties. The ionizable carboxyl groups in PFCAs make their log Kow dependent on pH. In this study, the log Kow values of neutral species of PFCAs (C4≤n≤14 ) were measured based on reversed-phase high-performance liquid chromatography (RP-HPLC) with the mobile phase pH varying in the range of 1.09-5.00. The relationship between log Kow and retention times was established using some reference compounds (including agrochemicals, polycyclic aromatic hydrocarbons) with known log Kow values, and then validated with alkyl fatty acids, which have similar chemical structures as PFCAs...
August 8, 2018: Environmental Pollution
Yi Hu, Yulian Li, Junyong He, Tao Liu, Kaisheng Zhang, Xingjiu Huang, Lingtao Kong, Jinhuai Liu
Industrial waste, urban sewage and aquaculture have led to severely increased grades of environment pollutants such as dyes, pesticides and fertilizer. The use of technologies for purifying contaminated waters can be difficult and toxic due to the anti-photolysis, anti-oxidation and anti-bio-oxidation characteristics of organic pollutants, and there is therefore a significant need for new approaches. Here, we report methods of Fenton oxidation and EDTA-Fe(III) Fenton-like oxidation which can be used to degrade malachite green (MG: a dye and antibiotic-like substance) from contaminated water...
August 16, 2018: Journal of Environmental Management
Ganesh M Bhoite, Prakash D Vaidya
In the present work, catalytic wet air oxidation (WAO) technique was applied to biomethanated spent wash from a local sugar factory. This wash water exhibited high biological oxygen demand (BOD5  = 8100 mg/L) and chemical oxygen demand (COD = 40,000 mg/L). The objectives of oxidative pre-treatment were two-fold, viz. efficient treatment of wash water and enhanced biogas recovery. For the catalytic oxidation process, two iron-based heterogeneous catalysts were employed, viz. Fe2 O3 and Fe/C. To synthesize the Fe/C catalyst, activated carbon (AC) support was modified either by thermal treatment or chemical treatment with nitric acid; accordingly, the catalyst was named as Fe/AC-T or Fe/AC-N...
August 16, 2018: Journal of Environmental Management
Yali Wang, Jianwei Zhao, Dongbo Wang, Yiwen Liu, Qilin Wang, Bing-Jie Ni, Fei Chen, Qi Yang, Xiaoming Li, Guangming Zeng, Zhiguo Yuan
Simultaneous sludge fermentation and nitrite removal is an effective approach to enhance nutrient removal from low carbon-wastewater. It was found in this work that the presence of nitrite largely promoted hydrogen production from acidic fermentation of waste activated sludge (WAS). The results showed that with an increase of nitrite from 0 to 250 mg/L, the maximal hydrogen yield increased from 8.5 to 15.0 mL/g VSS at pH 5.5 fermentation and 8.1-13.0 mL/g VSS at pH 6 fermentation. However, the maximal hydrogen yield from WAS fermentation at pH 8 remained almost constant (2...
August 6, 2018: Water Research
Yongli Ye, Jian Ji, Fuwei Pi, Huicheng Yang, Jie Liu, Yinzhi Zhang, Shuang Xia, Jiasheng Wang, Dan Xu, Xiulan Sun
Antioxidant evaluation of bioactive compounds is limited, since many methods lack a real physiological environment that can be used conveniently and intuitively. In this study, a simple, label-free and effective electrochemical biosensor method has been developed to evaluate the antioxidant effect of phloretin (Ph) by 3D cell modification on a glassy carbon electrode (GCE). In response to this, A549 cells were immobilized onto a self-assembled ʟ-cysteine/gold nanoparticle (AuNPs/ʟ-Cys)-modified GCE surface by a simple drop casting after encapsulated in alginate...
July 26, 2018: Biosensors & Bioelectronics
Krista A Barzen-Hanson, Rebecca A Wilkes, Ludmilla Aristilde
As remnants of plant wastes or plant secretions, carbohydrates are widely found in various environmental matrices. Carbohydrate-containing feedstocks represent important carbon sources for engineered bioproduction of commodity compounds. Routine monitoring and quantitation of heterogenous carbohydrate mixtures requires fast, accurate, and precise analytical methods. Here we present two methods to quantify carbohydrates mixtures by coupling hydrophilic interaction liquid chromatography with electrospray ionization high-resolution mass spectrometry...
August 12, 2018: Carbohydrate Research
Manee Patanapongpibul, Changde Zhang, Guanglin Chen, Shanchun Guo, Qiang Zhang, Shilong Zheng, Guangdi Wang, Qiao-Hong Chen
Our earlier studies indicate that (1E,4E)-1,5-bis(1-alkyl-1H-imidazol-2-yl)penta-1,4-diene-3-ones and (1E,4E)-1,5-bis(1-alkyl-1H-benzo[d]imidazol-2-yl)penta-1,4-diene-3-ones exhibit up to 121-fold greater antiproliferative potency than curcumin in human prostate cancer cell models, but only 2-10 fold increase in mouse plasma concentrations. The present study aims to further optimize them as anti-prostate cancer agents with both good potency and bioavailability. (1E,4E)-1,5-Bis(1H-imidazol-2-yl)penta-1,4-diene-3-one, the potential metabolic product of (1E,4E)-1,5-bis(1-alkyl-1H-imidazol-2-yl)penta-1,4-diene-3-ones, was synthesized and evaluated for its anti-proliferative activity...
August 13, 2018: Bioorganic & Medicinal Chemistry
Mònica Rosell, Jordi Palau, Siti Hatijah Mortan, Gloria Caminal, Albert Soler, Orfan Shouakar-Stash, Ernest Marco-Urrea
Chlorinated ethanes are frequent groundwater contaminants but compound specific isotope analysis (CSIA) has been scarcely applied to investigate their degradation pathways. In this study, dual carbon and chlorine isotope fractionation was used to investigate for the first time the anoxic biodegradation of 1,1,2-trichloroethane (1,1,2-TCA) using a Dehalogenimonas-containing culture. The isotopic fractionation values obtained for the biodegradation of 1,1,2-TCA were ɛC  = -6.9 ± 0.4‰ and ɛCl  = -2...
August 6, 2018: Science of the Total Environment
Yongxing Cui, Linchuan Fang, Xiaobin Guo, Fu Han, Wenliang Ju, Luping Ye, Xia Wang, Wenfeng Tan, Xingchang Zhang
Soil microbial metabolism is vital for nutrient cycling and aboveground ecosystem stability. A general understanding of microbial metabolism and nutrient limitation under human disturbance in arid and semi-arid regions, which are the largest and most fragile oligotrophic ecosystems globally, however, is still limited. We quantified and compared the characteristics of nutrient limitation of soil microbes under natural/artificial grassland and shrubland, an ecological forest, an economic forest, and sloped cropland in typical arid and semi-arid ecosystems on the Loess Plateau, China...
August 15, 2018: Science of the Total Environment
Xing-Pan Guo, Yi Yang, Zuo-Shun Niu, Da-Pei Lu, Chun-Hong Zhu, Jing-Nan Feng, Jia-Yuan Wu, Yu-Ru Chen, Fei-Yun Tou, Min Liu, Lijun Hou
In the contaminated coastal sediments, variations of microbial community can reflect the impact of anthropogenic activities. The identification, evaluation and monitoring of the potential bio-indicator species and biomarker communities are vital for the ecological studies in sedimentary environments. Based on the high-throughput sequencing, the microbial communities were characterized in the sediments along the Yangtze Estuary and its coastal area. The results showed that the structure and composition of microbial communities varied greatly among different sampling sites at the phyla level, especially for Euryarchaeota...
August 14, 2018: Science of the Total Environment
Yu Zou, Xiaochen Xu, Xiaojing Wang, Fenglin Yang, Shushen Zhang
This study presents a new way to achieve energy neutral wastewater treatment based on a combined nitrification, anammox, and denitrification (SNAD) process and photobioreactor (PBR) configuration with external recycling instead of aeration, and without an additional carbon source, using fixed-film-activated sludge technology (IFAS). The SNAD-PBR process achieved total nitrogen (TN) and phosphorus removal efficiencies of 90 and 100%, respectively. In addition, dissolved oxygen (DO) was controlled in the range 0...
August 4, 2018: Bioresource Technology
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