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https://www.readbyqxmd.com/read/28434197/multi-modal-signalling-in-estrildid-finches-song-dance-and-colour-are-associated-with-different-ecological-and-life-history-traits
#1
Ana Cristina R Gomes, Caterina Funghi, Masayo Soma, Michael D Sorenson, Gonçalo C Cardoso
Sexual traits (e.g., visual ornaments, acoustic signals, courtship behaviour) are often displayed together as multi-modal signals. Some hypotheses predict joint evolution of different sexual signals (e.g., to increase the efficiency of communication), or that different signals trade-off with each other (e.g., due to limited resources). Alternatively, multiple signals may evolve independently for different functions, or to communicate different information (multiple message hypothesis). We evaluated these hypotheses with a comparative study in the family Estrildidae, one of the largest songbird radiations, and one that includes many model species for research in sexual selection and communication...
April 23, 2017: Journal of Evolutionary Biology
https://www.readbyqxmd.com/read/28433972/paraneoplastic-jaundice-and-prostate-cancer
#2
Ana Claudia Vieira, Maria Joana Alvarenga, Jose Carlos Santos, Alberto Mello Silva
Cholestasis has numerous causes. We present the case of a 78-year-old man with a common diagnosis in this age group and gender but with an unusual presentation. There are only 11 articles published of patients with jaundice due to a paraneoplastic syndrome associated with prostate cancer. Interleukin 6 and other proinflammatory cytokines appear to contribute to the pathophysiology of this syndrome. Our patient remains symptom free 4 months after treatment initiation.
April 22, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28433860/cognitive-intrusion-of-pain-and-catastrophic-thinking-independently-explain-interference-of-pain-in-the-activities-of-daily-living
#3
Mojtaba Talaei-Khoei, Paul T Ogink, Ragini Jha, David Ring, Neal Chen, Ana-Maria Vranceanu
Patients with musculoskeletal illness often report that pain interferes with their ability to engage in activities of daily living. Catastrophic thinking is consistently depicted as an important cognitive factor that hinders adjustment to pain. Current research has also shown that pain negatively impacts an individual's ability to maintain attention on the task at hand. While a measure of the experience of cognitive intrusion of pain (ECIP) has been recently developed to quantify the extent of that impact, little research has explored this issue in everyday settings...
April 14, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/28433855/the-electrophysiology-of-neurohiv-a-systematic-review-of-eeg-and-meg-studies-in-people-with-hiv-infection-since-the-advent-of-highly-active-antiretroviral-therapy
#4
Ana Lucia Fernández-Cruz, Lesley K Fellows
OBJECTIVE: The Human Immunodeficiency Virus (HIV) has an impact on the brain, even when the infection is well-controlled with modern highly-active antiretroviral therapy (HAART). While dementia is rare in those on HAART, milder cognitive impairment is common. The causes, patterns, and evolution of brain dysfunction in people living with HIV remain uncertain. We evaluate whether electrophysiological methods provide informative measures of brain dysfunction in this population. METHODS: A systematic literature search identified studies that used EEG or MEG to evaluate persons living with HIV published between 1996 (when HAART became available) and 2016...
March 31, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/28433793/what-does-handedness-reveal-about-adhd-an-analysis-based-on-cpt-performance
#5
Eunice N Simões, Ana Lucia Novais Carvalho, Sergio L Schmidt
BACKGROUND: Attention-deficit/hyperactivity disorder (ADHD) is a developmental disorder. Continuous performance Tests (CPTs) aid the diagnosis. Handedness is linked to disabilities. OBJECTIVES: 1-To study the association between handedness and ADHD; 2-To verify the usefulness of the CPT in school settings; 3-To exam the relationship between handedness and CPT performance. METHOD: Each child was classified as right-consistent, left-consistent, or non-consistent...
April 20, 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/28433667/cognitive-impairment-and-heart-failure-systematic-review-and-meta-analysis
#6
REVIEW
Jane A Cannon, Peter Moffitt, Ana Cristina Perez-Moreno, Matthew R Walters, Niall M Broomfield, John J V McMurray, Terence J Quinn
BACKGROUND: Cognitive impairment and dementia are associated with a range of cardiovascular conditions including hypertension, coronary artery disease and atrial fibrillation. We aimed to describe the association with heart failure, summarising published data to give estimates around prevalence, incidence and relative risk of cognitive impairment/dementia in heart failure. METHODS: We searched multidisciplinary databases including MEDLINE (OVID), EMBASE (OVID), CINAHL (EBSCO), PsychINFO (EBSCO), Web of Science (Thomson Reuters) and CENTRAL (Cochrane Library) from inception until 31(st) May 2015...
April 19, 2017: Journal of Cardiac Failure
https://www.readbyqxmd.com/read/28433609/hb-moncloa-a-new-variant-of-haemoglobin-that-interferes-in-the-quantification-of-hb-a1c
#7
Torrejón María Josefa, Ortíz-Cabrera N Valentina, M Nieto Jorge, González Fernández Fernando-Ataúlfo, Villegas Ana, Martínez Rafael, Ropero Paloma
BACKGROUND: In most routine laboratories in Spain, the commonly used method for evaluating HbA1c is ion-exchange high performance liquid chromatography (HPLC). The presence of a variant of Hb may interfere with the quantification of HbA1c. AIMS: Here, we report a novel haemoglobin variant, named Hb Moncloa, which was found during a routine health check at the Hospital Clínico San Carlos in Moncloa (Madrid), Spain. METHODS AND RESULTS: Molecular characterization of β gene identified a novel transversion mutation [β80(EF4)Asn>Ser; HBB:c...
April 19, 2017: Clinical Biochemistry
https://www.readbyqxmd.com/read/28433563/aryl-thiosemicarbazones-in-vitro-and-immunomodulatory-activities-against-l-amazonensis
#8
Aline Caroline da Silva, Thiago André Ramos Dos Santos, Isis Viviane Bezerra da Silva, Marcos Victor Gregório de Oliveira, Diogo Rodrigo Magalhães Moreira, Ana Cristina Lima Leite, Valéria Rêgo Alves Pereira
Leishmaniasis is an infection caused by different species of Leishmania genus. Currently, there is no vaccine available for Leishmania infections in humans and conventional treatments are limited due to side effects. Therefore, the development of new antileishmanial drugs is an urgent need. In present study, we evaluated the cytotoxicity in host cells, leishmanicidal activity and immunomodulatory potential of seven aryl thiosemicarbazones. Host cell cytotoxicity was determined in peritoneal macrophages of BALB/c mouse, antiparasitic activity was determined against promastigotes and amastigotes of WHOM/00LTB 0016 strain of L...
April 19, 2017: Experimental Parasitology
https://www.readbyqxmd.com/read/28433406/results-of-the-implementation-of-a-multidisciplinary-programme-of-faecal-microbiota-transplantation-by-colonoscopy-for-the-treatment-of-recurrent-clostridium-difficile-infection
#9
Antonio López-Sanromán, Enrique Rodríguez de Santiago, Javier Cobo Reinoso, Rosa Del Campo Moreno, José Ramón Foruny Olcina, Sergio García Fernández, Ana García García de Paredes, Lara Aguilera Castro, Carlos Ferre Aracil, Agustín Albillos Martínez
INTRODUCTION: Recurrent Clostridium difficile infection (CDI) is common and often difficult to manage. Faecal microbiota transplant (FMT) is an effective therapeutic tool in these cases, although its applicability and effectiveness in Spain is currently unknown. AIM: To analyse the technical aspects, safety and effectiveness of the first consolidated FMT programme in Spain. METHODS: Retrospective descriptive study of all patients with recurrent CDI treated with FMT performed by colonoscopy in a tertiary centre after the implementation of a multidisciplinary protocol between March 2015 and September 2016...
April 19, 2017: Gastroenterología y Hepatología
https://www.readbyqxmd.com/read/28433237/inspiratory-muscle-training-improves-respiratory-muscle-strength-functional-capacity-and-quality-of-life-in-patients-with-chronic-kidney-disease-a-systematic-review
#10
Ana Irene Carlos de Medeiros, Helen Kerlen Bastos Fuzari, Catarina Rattesa, Daniella Cunha Brandão, Patrícia Érika de Melo Marinho
QUESTION: Does inspiratory muscle training improve respiratory muscle strength, functional capacity, lung function and quality of life of patients with chronic kidney disease? Does inspiratory muscle training improve these outcomes more than breathing exercises? DESIGN: Systematic review and meta-analysis of randomised trials. PARTICIPANTS: People with chronic kidney disease undergoing dialysis treatment. OUTCOME MEASURES: The primary outcomes were: maximal inspiratory pressure, maximal expiratory pressure, and distance covered on the 6-minute walk test...
April 2017: Journal of Physiotherapy
https://www.readbyqxmd.com/read/28433171/gellan-gum-based-physical-hydrogels-incorporating-highly-valuable-endogen-molecules-and-associating-bmp-2-as-bone-formation-platforms
#11
Rita López-Cebral, Ana Civantos, Viviana Ramos, Begoña Seijo, José Luis López-Lacomba, José Vicente Sanz-Casado, Alejandro Sanchez
Physical hydrogels have been designed for a double purpose: as growth factor delivery systems and as scaffolds to support cell colonization and formation of new bone. Specifically, the polysaccharide gellan gum and the ubiquitous endogenous molecules chondroitin, albumin and spermidine have been used as exclusive components of these hydrogels. The mild ionotropic gelation technique was used to preserve the bioactivity of the selected growth factor, rhBMP-2. In vitro tests demonstrated the effective delivery of rhBMP-2 in its bioactive form...
July 1, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28433166/chitosan-graphene-oxide-films-and-co2-dried-porous-aerogel-microspheres-interfacial-interplay-and-stability
#12
Sana Frindy, Ana Primo, Hamid Ennajih, Abou El Kacem Qaiss, Rachid Bouhfid, Mohamed Lahcini, El Mokhtar Essassi, Hermenegildo Garcia, Abdelkrim El Kadib
The intimate interplay of chitosan (CS) and graphene oxide (GO) in aqueous acidic solution has been explored to design upon casting, nanostructured "brick-and-mortar" films (CS-GO-f) and by acidic-to-basic pH inversion, porous CO2-dried aerogel microspheres (CS-GO-m). Owing to the presence of oxygenated functional groups in GO, good-quality crack-free hybrid films were obtained. Mechanical properties were improved independently of the GO content and it was found that a 20wt% loading affords hybrid film characterized with a Young modulus three times superior to that reached with the same loading of layered clay...
July 1, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28433159/glucuronoarabinoxylans-as-major-cell-walls-polymers-from-young-shoots-of-the-woody-bamboo-phyllostachys-aurea
#13
Víctor Martín Zelaya, Paula Virginia Fernández, Andrea Susana Vega, Anita Ida Mantese, Ana Ailén Federico, Marina Ciancia
Young shoots of Phyllostachys aurea showed glucuronoarabinoxylans (GAX) as the major hemicellulosic components, being extracted in major amounts with 1M KOH (ratio Xyl:Ara:GlcA, 100:67:8), but also with water, showing a broad structural variability. Mixed linkage glucans were also present, but in minor amounts, mostly concentrated in the 4M KOH extracts, while pectin polymers were very scarce. Arabinogalactan proteins were an important part of water extracts, determined by the presence of the typical arabinogalactan structures (3- and 6-linked Gal p; terminal and 5-linked Ara f), in addition to small amounts of hydroxyproline (2-3% of total protein) and positive reaction to Yariv's reagent...
July 1, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28433152/biodegradable-blends-of-urea-plasticized-thermoplastic-starch-utps-and-poly-%C3%AE%C2%B5-caprolactone-pcl-morphological-rheological-thermal-and-mechanical-properties
#14
Ana Carolina Correa, Vitor Brait Carmona, José Alexandre Simão, Luiz Henrique Capparelli Mattoso, José Manoel Marconcini
Biodegradable blends of urea plasticized thermoplastic starch (UTPS) and poly(ε-caprolactone) (PCL) were prepared in a co-rotating twin screw extruder. The UTPS and PCL content varied in a range of 25wt%. The materials were characterized by capillary rheometry, scanning electron microscopy (SEM), termogravimetry (TGA), differential scanning calorimetry (DSC) and tensile tests. Capillary rheometry showed better interaction between UTPS and PCL at 110°C than at 130°C. SEM showed immiscibility of all blends and good dispersion of UTPS in PCL matrix up to 50wt%...
July 1, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28432878/in-vitro-susceptibility-of-methicillin-resistant-staphylococcus-aureus-isolates-from-skin-and-soft-tissue-infections-to-vancomycin-daptomycin-linezolid-and-tedizolid
#15
Johanna Marcela Vanegas Múnera, Ana María Ocampo Ríos, Daniela Montoya Urrego, Judy Natalia Jiménez Quiceno
INTRODUCTION: Treatment of multidrug-resistant Gram-positive infections caused by Staphylococcus aureus remains as a clinical challenge due to emergence of new resistance mechanisms. Tedizolid is a next-generation oxazolidinone, recently approved for skin and soft tissues infections. We conducted a study to determine in vitro susceptibility to vancomycin, daptomycin, linezolid, and tedizolid in MRSA clinical isolates from adult patients with skin and soft tissue infections. MATERIAL AND METHODS: Methicillin-resistant S...
April 19, 2017: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28432860/high-ki-67-expression-is-associated-with-prolactin-secreting-pituitary-adenomas
#16
Bogdan Bălinişteanu, Anca Maria Cîmpean, Amalia Raluca Ceauşu, Ana Silvia Corlan, Eugen Melnic, Marius Raica
Pituitary adenomas represent the third most common primary intracranial tumor in neurosurgical practice. To understand the biological behaviour of the pituitary adenomas previous studies have determined the tumor proliferation rate using monoclonal antibodies targeted against the Ki-67 antigen. The aim of this study was to correlate the Ki-67 index with hormonal profiles of pituitary adenomas. The study included 50 pituitary adenoma cases. For histopathologic evaluation, the sections were stained with routine hematoxylin and eosin method...
April 22, 2017: Bosnian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/28432477/usefulness-of-non-magnifying-narrow-band-imaging-in-evis-exera-iii-video-systems-and-high-definition-endoscopes-to-diagnose-dysplasia-in-barrett-s-esophagus-using-the-barrett-international-nbi-group-bing-classification
#17
Oscar Nogales, Arancha Caballero-Marcos, Ana Clemente-Sánchez, Javier García-Lledó, Leticia Pérez-Carazo, Beatriz Merino, Carlos Carbonell, María López-Ibáñez, Cecilia González-Asanza
BACKGROUND: Narrow band imaging (NBI) allows identification of abnormal areas of Barrett's esophagus (BE) and could facilitate targeted biopsies. AIMS: We evaluated the diagnostic accuracy for dysplasia prediction using non-magnifying NBI in Evis Exera III processors and high-definition endoscopes using the Barrett International NBI Group (BING) classification, as well as inter/intraobserver agreement for dysplasia prediction and mucosal/vascular patterns. METHODS: Eight observers (4 staff endoscopists and 4 trainee endoscopists) evaluated 100 images selected from an anonymized bank of 470 photographs using the BING classification...
April 21, 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28432466/calpain-inhibition-prevents-flotillin-re-ordering-and-src-family-activation-during-capacitation
#18
Deneb Maldonado-García, Monica L Salgado-Lucio, Ana L Roa-Espitia, Tania Reyes-Miguel, Enrique O Hernández-González
Prior to fertilization, mammalian sperm undergo several molecular, biochemical and physiological changes in a process termed capacitation. However, the mechanisms explaining the involvement of cytoskeletal remodeling and membrane re-ordering in each process prior to fertilization remain poorly understood. We found that the migration of both flotillin microdomains and Src family kinases towards the apical ridge of guinea pig sperm occurs under capacitating conditions. This re-ordering is associated with spectrin cleavage by calpain...
April 22, 2017: Cell and Tissue Research
https://www.readbyqxmd.com/read/28432362/succinate-supplementation-improves-metabolic-performance-of-mixed-glial-cell-cultures-with-mitochondrial-dysfunction
#19
Susan Giorgi-Coll, Ana I Amaral, Peter J A Hutchinson, Mark R Kotter, Keri L H Carpenter
Mitochondrial dysfunction, the inability to efficiently utilise metabolic fuels and oxygen, contributes to pathological changes following traumatic spinal cord or traumatic brain injury (TBI). In the present study, we tested the hypothesis that succinate supplementation can improve cellular energy state under metabolically stressed conditions in a robust, reductionist in vitro model of mitochondrial dysfunction in which primary mixed glial cultures (astrocytes, microglia and oligodendrocytes) were exposed to the mitochondrial complex I inhibitor rotenone...
April 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28432270/discriminating-between-virilizing-ovary-tumors-and-ovary-hyperthecosis-in-postmenopausal-women-clinical-data-hormonal-profiles-and-image-studies
#20
Viviane Dos Reis Vieira Yance, José Antonio Miguel Marcondes, Michelle Patrocíneo Rocha, Cristiano Roberto Grimaldi Barcellos, Wagner Silva Dantas, Ana Flavia Assis Avila, Ronaldo Hueb Baroni, Filomena Marino Carvalho, Sylvia Asaka Yamashita Hayashida, Berenice Bilharinho Mendonça, Sorahia Domenice
The presence of virilizing signs associated with high serum androgen levels in postmenopausal women is rare. Virilizing ovarian tumors (VOTs) and ovarian stromal hyperthecosis (OH) are the most common etiologies in virilized postmenopausal women. The differential diagnosis between these two conditions is often difficult. OBJECTIVE: To evaluate the contribution of clinical features, hormonal profiles and radiological studies to the differential diagnosis of VOT and OH. DESIGN: A retrospective study...
April 21, 2017: European Journal of Endocrinology
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