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https://www.readbyqxmd.com/read/28550650/single-breath-hold-3-d-cine-imaging-of-the-left-ventricle-using-cartesian-sampling
#1
Jens Wetzl, Michaela Schmidt, François Pontana, Benjamin Longère, Felix Lugauer, Andreas Maier, Joachim Hornegger, Christoph Forman
OBJECTIVES: Our objectives were to evaluate a single-breath-hold approach for Cartesian 3-D CINE imaging of the left ventricle with a nearly isotropic resolution of [Formula: see text] and a breath-hold duration of [Formula: see text]19 s against a standard stack of 2-D CINE slices acquired in multiple breath-holds. Validation is performed with data sets from ten healthy volunteers. MATERIALS AND METHODS: A Cartesian sampling pattern based on the spiral phyllotaxis and a compressed sensing reconstruction method are proposed to allow 3-D CINE imaging with high acceleration factors...
May 26, 2017: Magma
https://www.readbyqxmd.com/read/28550649/improved-formula-see-text-determination-in-23-na-35-cl-and-17-o-mri-using-iterative-partial-volume-correction-based-on-1-h-mri-segmentation
#2
Sebastian C Niesporek, Reiner Umathum, Thomas M Fiedler, Peter Bachert, Mark E Ladd, Armin M Nagel
OBJECTIVE: Functional parameters can be measured with the help of quantitative non-proton MRI where exact relaxometry parameters are needed. Investigation of [Formula: see text] is often biased by strong partial volume (PV) effects. Hence, in this work a PV correction algorithm approach was evaluated that uses iteratively adapted [Formula: see text]-values and high-resolution structural (1)H data to determine transverse relaxation in non-proton MRI more accurately. MATERIALS AND METHODS: Simulations, a phantom study and in vivo (23)Na, (17)O and (35)Cl MRI measurements of five healthy volunteers were performed to evaluate the algorithm...
May 26, 2017: Magma
https://www.readbyqxmd.com/read/28550471/blood-lactate-accumulation-decreases-during-the-slow-component-of-oxygen-uptake-without-a-decrease-in-muscular-efficiency
#3
J M O'Connell, J M Weir, B R MacIntosh
Pulmonary oxygen uptake ([Formula: see text]) slowly increases during exercise above the anaerobic threshold, and this increase is called the slow component of [Formula: see text]. The mechanism of the increase in [Formula: see text] is assumed to be due to increasing energy cost associated with increasingly inefficient muscle contraction. We hypothesized that the increase in [Formula: see text] would be accompanied by a constant or increasing rate of accumulation of blood lactate, indicating sustained anaerobic metabolism while [Formula: see text] increased...
May 26, 2017: Pflügers Archiv: European Journal of Physiology
https://www.readbyqxmd.com/read/28550406/statistical-shape-modelling-to-aid-surgical-planning-associations-between-surgical-parameters-and-head-shapes-following-spring-assisted-cranioplasty
#4
Naiara Rodriguez-Florez, Jan L Bruse, Alessandro Borghi, Herman Vercruysse, Juling Ong, Greg James, Xavier Pennec, David J Dunaway, N U Owase Jeelani, Silvia Schievano
PURPOSE: Spring-assisted cranioplasty is performed to correct the long and narrow head shape of children with sagittal synostosis. Such corrective surgery involves osteotomies and the placement of spring-like distractors, which gradually expand to widen the skull until removal about 4 months later. Due to its dynamic nature, associations between surgical parameters and post-operative 3D head shape features are difficult to comprehend. The current study aimed at applying population-based statistical shape modelling to gain insight into how the choice of surgical parameters such as craniotomy size and spring positioning affects post-surgical head shape...
May 26, 2017: International Journal of Computer Assisted Radiology and Surgery
https://www.readbyqxmd.com/read/28549974/evaluation-of-tacrolimus-sorption-to-pvc-and-non-pvc-based-tubes-in-administration-sets-pump-method-vs-drip-method
#5
Su-Eon Jin, Seungho Jeon, Hyo-Jin Byon, Sung-Joo Hwang
Tacrolimus sorption to tubes was evaluated using pump and drip methods For tubes, polyvinylchloride (PVC)- and non-PVC-based (polyurethane [PU] and polyolefin [PO]) tubes were used. First, inner surface properties of tubes were analyzed using field emission scanning electron microscopy and X-ray photoelectron spectroscopy. Tacrolimus was quantitatively analyzed using high-performance liquid chromatography with UV detection. For kinetic sorption analysis, diluted tacrolimus to 10μg/mL was passed through 1-m-long tubes at 10mL/h...
May 23, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28548953/from-rapalogs-to-anti-aging-formula
#6
Mikhail V Blagosklonny
Inhibitors of mTOR, including clinically available rapalogs such as rapamycin (Sirolimus) and Everolimus, are gerosuppressants, which suppress cellular senescence. Rapamycin slows aging and extends life span in a variety of species from worm to mammals. Rapalogs can prevent age-related diseases, including cancer, atherosclerosis, obesity, neurodegeneration and retinopathy and potentially rejuvenate stem cells, immunity and metabolism. Here, I further suggest how rapamycin can be combined with metformin, inhibitors of angiotensin II signaling (Losartan, Lisinopril), statins (simvastatin, atorvastatin), propranolol, aspirin and a PDE5 inhibitor...
May 22, 2017: Oncotarget
https://www.readbyqxmd.com/read/28548501/structure-and-properties-of-sodium-enneaborate-na2-b8o11-oh-4-%C3%A2-b-oh-3%C3%A2-2h2o
#7
Doinita Neiner, Yulia V Sevryugina, Larry S Harrower, David M Schubert
Millions of tons of sodium borates are used annually by global industries in diverse applications important to modern society. The Na2O-B2O3-H2O phase diagram in the 0-100 °C temperature range contains 13 unique hydrated crystalline sodium borates, including five important industrial products. Structures were previously reported for each of these except for that having the highest boron content, known as sodium enneaborate, Na4B18O29·11H2O or 2Na2O·9B2O3·11H2O (1). Here we report the single-crystal structure of 1, revealing the structural formula Na2[B8O11(OH)4]·B(OH)3·2H2O, and describe some of its properties and relationships to other sodium borates...
May 26, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28548299/a-noninvasive-diagnosis-of-hepatic-fibrosis-by-biofibroscore%C3%A2-in-chronic-hepatitis-c-patients
#8
Chen-Hua Liu, Chun-Jen Liu, Chun-Ming Hong, Tung-Hung Su, Hung-Chih Yang, Kuei-Ming Chen, Yi-Ping Huang, Yu-Ming Yeh, Hui-Lan Tien, Yuan-Chih Liu, Jia-Horng Kao, Ding-Shinn Chen, Pei-Jer Chen
BACKGROUND & AIMS: The diagnostic accuracy of a novel serological panel (BioFibroScore®) to predict hepatic fibrosis in patients with chronic hepatitis C virus (HCV) infection is unknown. METHODS: Three markers of BioFibroScore®, including urokinase plasminogen activator (uPA), matrix metalloproteinase-9 (MMP-9), and beta-2 microglobulin (β2M), were retrospectively evaluated in 635 HCV-infected patients who received percutaneous liver biopsy and FibroScan®. The formula of BioFibroScore® to predict the severity of hepatic fibrosis was developed by Adaboost algorithm...
May 26, 2017: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28548217/tellurite-squarate-driven-assembly-of-a-new-family-of-nanoscale-clusters-based-on-mo2o2s2-2
#9
Lee Cronin, Jamie Purcell, Haralampos Miras, De-Liang Long, Panagiota Markopoulou
We report the preparation and characterization of a new family of four polyoxothiometalate (POTM) clusters, with varying size and complexity, based upon the dimeric [Mo2O2S2(H2O)6]2+ with the general formula (NMe4)aKb[(Mo2O2S2)c(TeO4)d(C4O4)e(OH)f] where a,b,c,d,e,f = {1,7,14,2,4,10} = 1, {Mo28Te2}; {2,26,36,4,10,48} = 2, {Mo72Te12}; {0,11,15,3,3,21} = 3, {Mo30Te3}; {2,6,12,2,4,16} = 4, {Mo24Te2}. The incorporation of tellurite anions allowed the fine tuning of the templation and bridging of the available building blocks leading to new topologies of increased complexity...
May 26, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28548047/evidence-for-the-antiferromagnetic-ground-state-of-zr2tial-a-first-principles-study
#10
P V Sreenivasa Reddy, V Kanchana, G Vaitheeswaran, Andrei V Ruban, N E Christensen
A detailed study on the ternary Zr-based intermetallic compound Zr2TiAl has been carried out using first-principles electronic structure calculations. From the total energy calculations, we find an antiferromagnetic L11-like (AFM) phase with alternating (1 1 1) spin-up and spin-down layers to be a stable phase among some others with magnetic moment on Ti being 1.22 [Formula: see text]. The calculated magnetic exchange interaction parameters of the Heisenberg Hamiltonian and subsequent Heisenberg Monte Carlo simulations confirm that this phase is the magnetic ground structure with Néel temperature between 30 and 100 K...
May 26, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/28547837/does-body-image-influence-the-relationship-between-body-weight-and-breastfeeding-maintenance-in-new-mothers
#11
Vivien Swanson, Alice Keely, Fiona C Denison
OBJECTIVES: Obese women have lower breastfeeding initiation and maintenance rates than healthy weight women. Research generally focuses on biomedical explanations for this. Psychosocial factors including body image and well-being after childbirth are less well understood as predictors of breastfeeding. In obese and healthy weight women, we investigated changes in body image between 72 hrs post-delivery and 6-8 weeks post-natal, studying how women's body image related to breastfeeding initiation and maintenance...
May 26, 2017: British Journal of Health Psychology
https://www.readbyqxmd.com/read/28547651/photoplethysmography-for-blood-volumes-and-oxygenation-changes-during-intermittent-vascular-occlusions
#12
T Y Abay, P A Kyriacou
Photoplethysmography (PPG) is an optical technique that measures blood volume variations. The main application of dual-wavelength PPG is pulse oximetry, in which the arterial oxygen saturation (SpO[Formula: see text]) is calculated noninvasively. However, the PPG waveform contains other significant physiological information that can be used in conjunction to SpO[Formula: see text] for the assessment of oxygenation and blood volumes changes. This paper investigates the use of near infrared spectroscopy (NIRS) processing techniques for extracting relative concentration changes of oxygenated ([Formula: see text]HbO[Formula: see text]), reduced ([Formula: see text]HHb) and total haemoglobin ([Formula: see text]tHb) from dual-wavelength PPG signals during intermittent pressure-increasing vascular occlusions...
May 25, 2017: Journal of Clinical Monitoring and Computing
https://www.readbyqxmd.com/read/28547001/new-mathematical-model-for-the-surface-area-of-the-left-ventricle-by-the-truncated-prolate-spheroid
#13
José Sérgio Domingues, Marcos de Paula Vale, Carlos Barreira Martinez
The main aim of this study was the formula application of the superficial area of a truncated prolate spheroid (TPS) in Cartesian coordinates in obtaining a cardiac parameter that is not so much discussed in literature, related to the left ventricle (LV) surface area of the human heart, by age and sex. First we obtain a formula for the area of a TPS. Then a simple mathematical model of association of the axes measures of a TPS with the axes of the LV is built. Finally real values of the average dimensions of the humans LV are used to measure surface areas approximations of this heart chamber...
2017: TheScientificWorldJournal
https://www.readbyqxmd.com/read/28546879/histological-evaluation-and-management-of-rare-case-of-supernumerary-ghost-teeth
#14
Dino Re, Elena Canciani, Corinne Poli, Laura Buccarella, Marilisa Toma, Andrea Carlo Butti, Claudia Dellavia
Supernumerary teeth are teeth that exceed the normal dental formula. Their prevalence in the permanent dentition is 1-14% and they occur more frequently in maxilla with a sex ratio of 2 : 1 in favor of males. They are often associated with syndromes but there are examples of nonsyndromic multiple supernumerary teeth reported in the literature. CBCT is usually the best exam for radiographic diagnosis and treatment planning, because it provides 3D information about location and morphology of supernumerary teeth...
2017: Case Reports in Dentistry
https://www.readbyqxmd.com/read/28546304/comparison-of-methods-of-estimating-creatinine-clearance-in-pediatric-patients
#15
Danielle Padgett, Andrew Ostrenga, Lindsey Lepard
PURPOSE: A retrospective study was conducted to compare various methods of measuring serum creatinine (SCr) values for use in pediatric renal function assessments, including a method aligned with a recently implemented national SCr testing standard. METHODS: Demographic, medication-use, and selected laboratory data were collected from the hospital records of a sample of pediatric patients (n = 91) who underwent 12- or 24-hour timed urine collection for determination of creatinine clearance (CLcr) over a 2-year period...
June 1, 2017: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/28546117/analysis-on-pathogenic-and-virulent-characteristics-of-the-cronobacter-sakazakii-strain-baa-894-by-whole-genome-sequencing
#16
Xuerui Bao, Ling Yang, Lequn Chen, Bing Li, Lin Li, Yanyan Li, Zhenbo Xu
Cronobacter sakazakii is an opportunistic pathogen responsible for necrotizing enterocolitis, meningitis and septicaemia especially to infant and neonate, with high lethality ranging in 40%-80%. This strain is able to survive in infant milk formula and possesses capability of pathogenicity and virulence, biofilm formation, and high resistance to elevated osmotic, low pH, heat, oxidation, and desiccasion. This study is aims to investigate the molecular characteristics of Cronobacter sakazakii BAA 894, including mechanisms of its invasion and adherence, biofilm formation, unusual resistance to environmental stress employing whole genome sequencing and comparative genomics...
May 22, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28545589/gastrointestinal-tolerance-of-low-fodmap-oral-nutrition-supplements-in-healthy-human-subjects-a-randomized-controlled-trial
#17
Jennifer Erickson, Renee Korczak, Qi Wang, Joanne Slavin
BACKGROUND: There has been increasing interest in utilizing a diet low in fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAPs) for the treatment of irritable bowel syndrome (IBS), a functional gastrointestinal disease. While studies have indicated that this diet can be effective at symptom reduction, it is a restrictive diet and patients may find it challenging to find low FODMAP products to meet their nutrient needs. The primary objective of this study was to assess the gastrointestinal (GI) tolerance of three low FODMAP oral nutrition supplements (ONS) in healthy adults...
May 25, 2017: Nutrition Journal
https://www.readbyqxmd.com/read/28545434/effects-of-dangguibuxue-decoction-on-rat-glomerular-mesangial-cells-cultured-under-high-glucose-conditions
#18
Xiao-Dan Ren, Ying-Wen Zhang, Xiu-Ping Wang, Ya-Rong Li
BACKGROUND: Dysfunction of glomerular mesangial cells (GMCs) plays an important role in pathogenesis of diabetic nephropathy. Here, we investigated the effects of Dangguibuxue decoction (DBD), an herbal traditional Chinese medicinal (TCM) formula composed of Astragali Radix and Angelicae Sinensis Radix, on GMC proliferation and fibrogenesis under high-glucose (HG) conditions. METHODS: Sixty male Sprague Dawley rats were divided into 5 groups and administered intragastric 0...
May 25, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28545304/tracing-sources-of-nitrate-using-water-chemistry-land-use-and-nitrogen-isotopes-in-the-ganjiang-river-china
#19
Peng Wang, Junzheng Liu, Shuhua Qi, Shiqin Wang, Xiaoling Chen
In this work, we traced sources of nitrate in the Ganjiang River, a major tributary of Yangtze River, China, by analysing the water chemistry, nitrogen isotopes and land use. Water samples from 20 sites in the main stream and tributaries were collected in the dry and wet seasons. The [Formula: see text] ranged from 0.97 to 8.60 ‰, and was significantly higher in the wet season than in the dry season, and significantly higher in tributaries than in the main stream. In the dry season, [Formula: see text] concentrations and [Formula: see text] were significantly negatively correlated with forest and grassland areas, and positively correlated with paddy field and residential area...
May 25, 2017: Isotopes in Environmental and Health Studies
https://www.readbyqxmd.com/read/28545051/increased-risk-for-diabetes-development-in-subjects-with-large-variation-in-total-cholesterol-levels-in-2-827-950-koreans-a-nationwide-population-based-study
#20
Eun-Jung Rhee, Kyungdo Han, Seung-Hyun Ko, Kyung-Soo Ko, Won-Young Lee
BACKGROUND: Recent studies suggest a role for hyperlipidemia in the development of diabetes. The aim of this study is to analyze the relationship between variations of total cholesterol (TC) levels and the risk for type 2 diabetes development from a Korean nationwide population-based database. MATERIALS AND METHODS: We examined the General Health Check-up sub-dataset of the Korean National Health Insurance Service (NHIS) of 2,827,950 participants who had at least three health check-ups between 2002 and 2007, and were not reported to have diabetes during that time...
2017: PloS One
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