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F Kachkouch, H Franklin, A Tinel
The characteristics of the reflection and transmission by a fluid-loaded double porosity layer are studied. The medium obeys the two-pressure field poroelastic phenomenological model of Berryman and Wang. The open pore hydraulic conditions applied at the interfaces yield factorized expressions for the coefficients exhibiting on the one hand a separation allowing to distinguish between symmetrical and antisymmetrical motions and on the other hand the way each of the three dilatational waves associate with the shear wave...
February 15, 2018: Ultrasonics
Nannan Wang, Xiaoning Zhao, Jiaxin Huai, Yiran Li, Congcong Cheng, Kaishun Bi, Ronghua Dai
ETHNOPHARMACOLOGICAL RELEVANCE: Huo Luo Xiao Ling Dan (HLXLD), a traditional Chinese medicine (TCM), is commonly used for the treatment of rheumatoid arthritis (RA). AIM OF THE STUDY: To explore the potential therapeutic mechanism of HLXLD on anti-inflammatory activity. MATERIALS AND METHODS: A metabolomic approach based on UFLC-MS/MS to profile arachidonic acid (AA) metabolic changes was used. The cyclooxygenase (COX) and lipoxygenase (LOX) catalyzed metabolites in plasma were quantified on 7, 14, 21, and 28 days after the rats injected with Complete Freund's adjuvant and orally administrated with HLXLD, methotrexate and dexamethasone in parallel as the positive control drugs...
February 20, 2018: Journal of Ethnopharmacology
Laurent Guilbert, Laura Vittadello, Marco Bazzan, Imed Mhaouech, Simon Messerschmidt, Mirco Imlau
Charge transport due to small polarons hopping among defective (bound polarons) and regular (free polarons) sites is shown to depend in a non-trivial way on the value of the stabilization energy provided by the lattice distortion surrounding the charge carriers. This energy, normally not directly accessible for bound polarons using spectroscopic techniques, is determined here by a combination of experimental and numerical methods for the important case of small electron polarons bound to [Formula: see text] defects in the prototype ferroelectric oxide lithium niobate...
February 23, 2018: Journal of Physics. Condensed Matter: An Institute of Physics Journal
Liping Tong, Katsuhiko Saito, Qixin Guo, Han Zhou, Xingmei Guo, Tongxiang Fan, Di Zhang
A correlation function between the Raman intensities and the nearest-neighbor mean-square relative displacement (MSRD) [Formula: see text] of local Bi-O bonds is successfully established based on x-ray absorption fine structure (XAFS) and temperature-dependent Raman spectra in the temperature range 77-300 K in amorphous and crystalline Gd2.95 Yb0.02 Bi0.02 Er0.01 Ga5 O12 . The structural symmetries of Gd2.95 Yb0.02 Bi0.02 Er0.01 Ga5 O12 are described by using [Formula: see text] of local Bi-O bonds. More importantly, Gd2...
February 23, 2018: Journal of Physics. Condensed Matter: An Institute of Physics Journal
Peng Fei, Yichao Jiang, Shaoying Gong, Ran Li, Yan Jiang, Xiujuan Yuan, Ziyuan Wang, Huaibin Kang, Md Aslam Ali
Cronobacter species (formerly Enterobacter sakazakii) are emerging opportunistic bacterial pathogens that can infect both infants and adults. This study was conducted to isolate and genotype diverse Cronobacter species from drinking water, chilled fresh pork, powdered infant formula, instant noodles, cookies, fruits, vegetables, and dishes in Northeast China and to evaluate the antibiotic resistance and susceptibility of the isolates. Thirty-four Cronobacter strains were isolated and identified: 21 C. sakazakii isolates (61...
February 23, 2018: Journal of Food Protection
Yuan-Chieh Lo, Yuh-Chung Hu, Pei-Zen Chang
Thermal characteristic analysis is essential for machine tool spindles because sudden failures may occur due to unexpected thermal issue. This article presents a lumped-parameter Thermal Network Model (TNM) and its parameter estimation scheme, including hardware and software, in order to characterize both the steady-state and transient thermal behavior of machine tool spindles. For the hardware, the authors develop a Bluetooth Temperature Sensor Module (BTSM) which accompanying with three types of temperature-sensing probes (magnetic, screw, and probe)...
February 23, 2018: Sensors
Brian Derbyshire
Radiographic measurement of two-dimensional acetabular cup wear is usually carried out on a series of follow-up radiographs of the patient's pelvis. Since the orientation of the pelvis might not be consistent at every X-ray examination, the resulting change in view of the wear plane introduces error into the linear wear measurement. This effect is amplified on some designs of cup in which the centre of the socket is several millimetres below the centre of the cup or circular wire marker. This study describes the formulation of a mathematical method to correct radiographic wear measurements for changes in pelvis orientation...
February 1, 2018: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
Xinzhuo Zhao, Liyao Liu, Shouliang Qi, Yueyang Teng, Jianhua Li, Wei Qian
OBJECTIVE: To distinguish benign from malignant pulmonary nodules using CT images is critical for their precise diagnosis and treatment. A new Agile convolutional neural network (CNN) framework is proposed to conquer the challenges of a small-scale medical image database and the small size of the nodules, and it improves the performance of pulmonary nodule classification using CT images. METHODS: A hybrid CNN of LeNet and AlexNet is constructed through combining the layer settings of LeNet and the parameter settings of AlexNet...
February 23, 2018: International Journal of Computer Assisted Radiology and Surgery
Erik P Andersson, Kerry McGawley
Purpose: The present study aimed to compare four methods of estimating anaerobic energy production during supramaximal exercise. Methods: Twenty-one junior cross-country skiers competing at a national and/or international level were tested on a treadmill during uphill (7°) diagonal-stride (DS) roller-skiing. After a 4-minute warm-up, a 4 × 4-min continuous submaximal protocol was performed followed by a 600-m time trial (TT). For the maximal accumulated O2 deficit (MAOD) method the [Formula: see text]O2 -speed regression relationship was used to estimate the [Formula: see text]O2 demand during the TT, either including (4+Y, method 1) or excluding (4-Y, method 2) a fixed Y-intercept for baseline [Formula: see text]O2 ...
2018: Frontiers in Physiology
Yuanyuan Huang, Renbang Zhao, Yencon Hung, Huiyu Gao, Penghui Zhang, Yang Wang, Mengying Sun, Dan Liu, Shuai Wang
The degradation process of acephate in aqueous solution with• OH and [Formula: see text] produced by60 Co-γ irradiation and electron pulse radiolysis was studied in the present paper. In the aqueous solution, acephate reacted with [Formula: see text] and transformed to transient species which can absorb weakly in the wavelength range of 300-400 nm and decay very fast. According to the decay of hydrated electron, the reaction rate constant of [Formula: see text] and acephate is (3.51 ± 0.076) × 109  dm3 ·mol-1 ·s-1 ...
February 2018: Saudi Journal of Biological Sciences
Wei-Shan Chiang, Daniel Georgi, Taner Yildirim, Jin-Hong Chen, Yun Liu
It is extremely challenging to measure the variation of pore surface properties in complex porous systems even though many porous materials have widely differing pore surface properties at microscopic levels. The surface heterogeneity results in different adsorption/desorption behaviors and storage capacity of guest molecules in pores. Built upon the conventional Porod's law scattering theory applicable mainly to porous materials with relatively homogeneous matrices, here we develop a generalized Porod's scattering law method (GPSLM) to study heterogeneous porous materials and directly obtain the variation of scattering length density (SLD) of pore surfaces...
February 22, 2018: Nature Communications
Kamaludin Dingle, Chico Q Camargo, Ard A Louis
Many systems in nature can be described using discrete input-output maps. Without knowing details about a map, there may seem to be no a priori reason to expect that a randomly chosen input would be more likely to generate one output over another. Here, by extending fundamental results from algorithmic information theory, we show instead that for many real-world maps, the a priori probability P(x) that randomly sampled inputs generate a particular output x decays exponentially with the approximate Kolmogorov complexity [Formula: see text] of that output...
February 22, 2018: Nature Communications
Panchanan Maiti, Leela Paladugu, Gary L Dunbar
BACKGROUND: Neuroinflammation and the presence of amyloid beta protein (Aβ) and neurofibrillary tangles are key pathologies in Alzheimer's disease (AD). As a potent anti-amyloid and anti-inflammatory natural polyphenol, curcumin (Cur) could be potential therapies for AD. Unfortunately, poor solubility, instability in physiological fluids, and low bioavailability limit its clinical utility. Recently, different lipid modifications in the formulae of Cur have been developed that would enhance its therapeutic potential...
February 23, 2018: BMC Neuroscience
T J Price, A P Hickman
Recent quantum calculations of rotationally inelastic collisions of NaK (A1 Σ+ ) with He or Ar in a cell experiment are analyzed using semiclassical approximations valid for large quantum numbers. The results suggest a physical interpretation of jm → j'm' transitions based on the vector model and lead to expressions that explicitly involve the initial and final polar angles of the angular momentum of the target molecule. The relation between the polar angle θ and the azimuthal quantum number m links the semiclassical results for the change in polar angle (θ → θ') to quantum results for an m → m' transition...
February 21, 2018: Journal of Chemical Physics
Charles Daultrey, John Hardman, Shahram Anari
Background: The nasal septum is composed of cartilaginous and bony components and an understanding of each component volume is essential in both functional and cosmetic surgery. Objectives: We sought to radiographically measure septal dimensions on cross sectional computer tomography (CT) images, establishing average parameters for normal anatomy among a single, Caucasian population group. Methods: One hundred and fifty consecutive sinus CT scan images were examined and 100 cases with appropriate sagittal views were included in the study...
February 19, 2018: Aesthetic Surgery Journal
Vanessa Rodríguez-Fanjul, Elena López-Torres, M Antonia Mendiola, Ana María Pizarro
Gold(III) compounds have received increasing attention in cancer research. Three gold complexes of general formula [AuIII L]Cl, where L is benzil bis(thiosemicarbazonate), compound 1, benzil bis(4-methyl-3-thiosemicarbazonate), compound 2, or benzil bis(4-cyclohexyl-3-thiosemicarbazonate), compound 3, have been synthesized and fully characterized, including the X-ray crystal structure of compound 3, confirming square-planar geometry around the gold(III) centre. Compound 1 showed moderate cytotoxicity and accumulation in MCF7 breast cancer cells but did not inhibit thioredoxin reductase (TrxR) activity and did not induce reactive oxygen species (ROS) production...
February 10, 2018: European Journal of Medicinal Chemistry
Ying Pan, Ling-Dong Kong
Fructose is a natural monosaccharide broadly used in modern society. Over the past few decades, epidemiological studies have demonstrated that high fructose intake is an etiological factor of metabolic syndrome (MetS). This review highlights research advances on fructose-induced MetS, especially the underlying pathophysiological mechanism as well as pharmacotherapy by traditional Chinese medicine (TCM), using the PubMed, Web of science, China National Knowledge Infrastructure, China Science and Technology Journal and Wanfang Data...
February 19, 2018: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
Mohammed A Kassem, Mohamed A Megahed, Sherif K Abu Elyazid, Fathy I Abd-Allah, Tamer M Abdelghany, Ahmed M Al-Abd, Khalid M El-Say
Serious adverse effects and low selectivity to cancer cells are the main obstacles of long term therapy with Tamoxifen (Tmx). This study aimed to develop Tmx-loaded span-based nano-vesicles for delivery to malignant tissues with maximum efficacy. The effect of three variables on vesicle size (Y1 ), zeta potential (Y2 ), entrapment efficiency (Y3 ) and the cumulative percent release after 24 h (Y4 ) were optimized using Box-Behnken design. The optimized formula was prepared and tested for its stability in different storage conditions...
February 22, 2018: AAPS PharmSciTech
Jie He, Hui Li, Shumei Zhang, Xiaogang Duan
The semiparametric additive hazards model is an important way for studying the effect of potential risk factors for right-censored time-to-event data. In this paper, we study the additive hazards model in the presence of auxiliary subgroup [Formula: see text]-year survival information. We formulate the known auxiliary information in the form of estimating equations, and combine them with the conventional score-type estimating equations for the estimation of the regression parameters based on the maximum empirical likelihood method...
February 22, 2018: Lifetime Data Analysis
Linda P M Pluymen, Alet H Wijga, Ulrike Gehring, Gerard H Koppelman, Henriëtte A Smit, L van Rossem
PURPOSE: To investigate whether early introduction of complementary foods (CF) is associated with an increased risk of overweight during childhood, and whether this association differs between formula-fed and breastfed infants. METHODS: We included 2611 participants that were born at term from a Dutch population-based birth cohort (n = 3963) designed to investigate the development of asthma and allergies. Parents kept records of their infant's age when CF were first introduced...
February 22, 2018: European Journal of Nutrition
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