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Rotator cuff injury

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https://www.readbyqxmd.com/read/28093363/alignment-of-collagen-fiber-in-knitted-silk-scaffold-for-functional-massive-rotator-cuff-repair
#1
Zefeng Zheng, Jisheng Ran, Weishan Chen, Yejun Hu, Ting Zhu, Xiao Chen, Zi Yin, Boon Chin Heng, Gang Feng, Huihui Le, Chenqi Tang, Jiayun Huang, Yangwu Chen, Yiting Zhou, Pioletti Dominique, Weiliang Shen, Hong-Wei Ouyang
: Rotator cuff tear is one of the most common types of shoulder injuries, often resulting in pain and physical debilitation. Allogeneic tendon-derived decellularized matrices do not have appropriate pore size and porosity to facilitate cell infiltration, while commercially-available synthetic scaffolds are often inadequate at inducing tenogenic differentiation. The aim of this study is to develop an advanced 3D aligned collagen/silk scaffold (ACS) and investigate its efficacy in a rabbit massive rotator cuff tear model...
January 13, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28077355/no-evidence-for-the-use-of-stem-cell-therapy-for-tendon-disorders-a-systematic-review
#2
Haiko I M F L Pas, Maarten H Moen, Hidde J Haisma, Marinus Winters
INTRODUCTION: Stem cells have emerged as a new treatment option for tendon disorders. We systematically reviewed the current evidence for stem cell therapy in tendon disorders. METHODS: Randomised and non-randomised controlled trials, cohort studies and case series with a minimum of 5 cases were searched in MEDLINE, CENTRAL, EMBASE, CINAHL, PEDro and SPORTDiscus. In addition, we searched grey literature databases and trial registers. Only human studies were included and no time or language restrictions were applied to our search...
January 11, 2017: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/28070148/comparison-of-the-epidemiology-and-outcomes-of-traumatic-and-nontraumatic-rotator-cuff-tears
#3
Takeshi Teratani
OBJECTIVE: The purpose of this study was to investigate the differences in the epidemiology and outcomes of traumatic and nontraumatic rotator cuff tears. METHODS: Thirty-three patients with traumatic and 46 with nontraumatic rotator cuff tears were included. RESULTS: The rate of injury to the long head of the biceps was significantly higher in the traumatic group. Preoperative active forward elevation was significantly lower in the traumatic group...
March 2017: Journal of Orthopaedics
https://www.readbyqxmd.com/read/28036238/clinical-relevance-of-classifying-massive-rotator-cuff-tears
#4
Hyun Soo Ok, Byung Guk Kim, Won Chul Choi, Chul Gie Hong, Jee Woong Kim, Jae Hwa Kim
BACKGROUND: Studies on the results of arthroscopic repair of massive rotator cuff tears have reported widely varied prognoses. Among other factors, the sizable discrepancy can be attributable to the fact that the current definition of massive rotator cuff tears covers an extensive area of tendons. HYPOTHESIS: Functional and radiological results according to subgroups would show significant inter-subgroup differences preoperatively and postoperatively. STUDY DESIGN: Cohort study; Level of evidence, 2...
January 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28001327/supraspinatus-tendon-overuse-results-in-degenerative-changes-to-tendon-insertion-region-and-adjacent-humeral-cartilage-in-a-rat-model
#5
Akia N Parks, Jennifer McFaline-Figueroa, Anne Coogan, Emma Poe-Yamagata, Robert E Guldberg, Manu O Platt, Johnna S Temenoff
The etiology of rotator cuff tendon overuse injuries is still not well understood. Furthermore, how this overuse injury impacts other components of the glenohumeral joint, including nearby articular cartilage, is also unclear. Therefore, this study sought to better understand the time course of tendon protease activity in a rat model of supraspinatus overuse, as well as determine effects of 10 weeks of overuse on humeral head articular cartilage. For these studies, multiplex gelatin zymography was used to characterize protease activity profiles in tendon and cartilage, while histological scoring/mechanical testing and micro-computed tomography (μCT) imaging were used to quantify structural damage in the supraspinatus tendon insertion and humeral articular cartilage, respectively...
December 21, 2016: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/27965219/effects-of-platelet-rich-plasma-and-triamcinolone-acetonide-on-interleukin-1%C3%A3-stimulated-human-rotator-cuff-derived-cells
#6
T Muto, T Kokubu, Y Mifune, A Inui, R Sakata, Y Harada, F Takase, M Kurosaka
OBJECTIVES: Triamcinolone acetonide (TA) is widely used for the treatment of rotator cuff injury because of its anti-inflammatory properties. However, TA can also produce deleterious effects such as tendon degeneration or rupture. These harmful effects could be prevented by the addition of platelet-rich plasma (PRP), however, the anti-inflammatory and anti-degenerative effects of the combined use of TA and PRP have not yet been made clear. The objective of this study was to determine how the combination of TA and PRP might influence the inflammation and degeneration of the rotator cuff by examining rotator cuff-derived cells induced by interleukin (IL)-1ß...
December 2016: Bone & Joint Research
https://www.readbyqxmd.com/read/27935559/application-of-a-model-to-analyze-shoulder-biomechanics-in-adult-patients-with-spinal-cord-injury-when-walking-with-crutches-in-two-different-gait-patterns
#7
Enrique Perez-Rizo, Fernando Trincado-Alonso, Soraya Pérez-Nombela, Antonio Del Ama-Espinosa, Fernando Jiménez-Díaz, Vicente Lozano-Berrio, Angel Gil-Agudo
BACKGROUND: Specific biomechanical models have been developed to study gait using crutches. Clinical application of these models is needed in adult spinal cord injury (SCI) population walking with different patterns of gait with crutches to prevent overuse shoulder injuries. OBJECTIVE: To apply a biomechanical model in a clinical environment to analyze shoulder in adult SCI patients walking with two different patterns of gait with crutches: two point reciprocal gait (RG) and swing-through gait (SG)...
December 8, 2016: NeuroRehabilitation
https://www.readbyqxmd.com/read/27904235/management-of-acute-work-related-shoulder-injuries-by-an-early-shoulder-assessment-program-efficiency-of-imaging-investigations
#8
Helen Razmjou, Sandra Lincoln, Christopher Geddes, Dragana Boljanovic, Iona Macritchie, Caterina Virdo-Cristello, Danielle Medeiros, Robin R Richards
Purpose: There has been a significant increase in the number of costly investigations of the shoulder joint over the past decade. The purposes of this study were to (1) describe the diagnostic imaging investigations ordered for injured workers seen at an Early Shoulder Physician Assessment (ESPA) program, (2) evaluate the impact of these investigations on final diagnosis and management, and (3) examine how efficient the program was by determining the appropriateness of referrals and whether costly imaging was justified...
2016: Physiotherapy Canada. Physiothérapie Canada
https://www.readbyqxmd.com/read/27891243/a-comprehensive-musculoskeletal-and-peripheral-nervous-system-assessment-of-war-related-bilateral-upper-extremity-amputees
#9
Mostafa Allami, Batool Mousavi, Mehdi Masoumi, Ehsan Modirian, Hadi Shojaei, Fatemeh Mirsalimi, Maryam Hosseini, Pirouz Pirouzi
BACKGROUND: Upper limb amputations are one of the unpleasant war injuries that armed forces are exposed to frequently. The present study aimed to assess the musculoskeletal and peripheral nervous systems in Iraq-Iran war veterans with bilateral upper extremity amputation. METHODS: The study consisted of taking a history and clinical examinations including demographic data, presence and location of pain, level of amputation, passive and active ranges of movement of the joints across the upper and lower extremities and spine, manual palpation, neurological examination, blood circulation pulses and issues related to a prosthetic limb...
2016: Military Medical Research
https://www.readbyqxmd.com/read/27855678/augmentation-and-repair-of-tendons-using-demineralised-cortical-bone
#10
Sherif Elnikety, Catherine J Pendegrass, Roberta Ferro de Godoy, Charles Holden, Gordon W Blunn
BACKGROUND: In severe injuries with loss of tendon substance a tendon graft or a synthetic substitute is usually used to restore functional length. This is usually associated with donor site morbidity, host tissue reactions and lack of remodelling of the synthetic substitutes, which may result in suboptimal outcome. A biocompatible graft with mechanical and structural properties that replicate those of normal tendon and ligament has so far not been identified. The use of demineralised bone for tendon reattachment onto bone has been shown to be effective in promoting the regeneration of a normal enthesis...
November 17, 2016: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/27830921/post-operative-physical-therapy-program-for-latissimus-dorsi-and-teres-major-tendons-transfer-to-rotator-cuff-in-children-with-obstetrical-brachial-plexus-injury
#11
Yasser A Safoury, Mohamed Eldesoky, Enas E Abutaleb, Mohamed Raafat, Ahmed M Gaber
BACKGROUND: The transfer latissimus dorsi and teres major tendons to rotator cuff have been developed to rebalance the muscular dysfunction and improve shoulder range of motion in children with obstetrical brachial plexus palsy (OBPP). No previous study reported the ideal postoperative physical therapy program for these cases. AIM: The aim of the present study was to design appropriate postoperative physical therapy (PT) program after latissimus dorsi and teres major tendons transfer to rotator cuff in OBPP to improve upper limb function...
November 10, 2016: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27826596/return-to-sports-after-arthroscopic-treatment-of-rotator-cuff-calcifications-in-athletes
#12
Maximiliano Ranalletta, Luciano A Rossi, Adrian Sirio, Guillermina Bruchmann, Gastón D Maignon, Santiago L Bongiovanni
BACKGROUND: Arthroscopic treatment of calcific deposits of rotator cuff tears has been described with successful results in the general population. However, despite the high frequency of this condition, there is no information in the literature regarding arthroscopic treatment of rotator cuff calcifications in athletes. PURPOSE: To analyze the time to return to sport, clinical outcomes, and complications of complete arthroscopic removal of intratendinous calcific deposits and repair of the tendon lesion without acromioplasty in athletes...
October 2016: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/27814833/acr-appropriateness-criteria-imaging-after-shoulder-arthroplasty
#13
Soterios Gyftopoulos, Zehava S Rosenberg, Catherine C Roberts, Jenny T Bencardino, Marc Appel, Steven J Baccei, R Carter Cassidy, Eric Y Chang, Michael G Fox, Bennett S Greenspan, Mary G Hochman, Jon A Jacobson, Douglas N Mintz, Joel S Newman, Nehal A Shah, Kirstin M Small, Barbara N Weissman
There has been a rapid increase in the number of shoulder arthroplasties, including partial or complete humeral head resurfacing, hemiarthroplasty, total shoulder arthroplasty, and reverse total shoulder arthroplasty, performed in the United States over the past two decades. Imaging can play an important role in diagnosing the complications that can occur in the setting of these shoulder arthroplasties. This review is divided into two parts. The first part provides a general discussion of various imaging modalities, comprising radiography, CT, MRI, ultrasound, and nuclear medicine, and their role in providing useful, treatment-guiding information...
November 2016: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/27814629/advances-in-the-treatment-of-rotator-cuff-lesions-by-cytokines
#14
Genbin Wu, Peng Cheng Xu, Peng Wu, Kaihua Hu, Yeqing Sun, Biao Cheng, Yong Lu
Rotator cuff tears are one of the most common shoulder problems that usually require operative treatments. Therapeutic options used to repair ruptured tendons have consisted of suture, autografts, allografts, and synthetic prostheses. Although surgical treatments have improved dramatically up to now, shoulder pathology is still challenging to orthopedic surgery primarily because these injuries often respond poorly to treatment and require prolonged rehabilitation. Recent attention has focused on several biologic pathways which can augment function to tendon healing, consequently leading to the identification of growth factors involved in this process...
January 1, 2017: Frontiers in Bioscience (Landmark Edition)
https://www.readbyqxmd.com/read/27800039/a-prospective-comparative-study-of-high-resolution-ultrasound-and-mri-in-the-diagnosis-of-rotator-cuff-tears-in-a-tertiary-hospital-of-north-india
#15
Narvir Singh Chauhan, Ajay Ahluwalia, Yash Paul Sharma, Lokesh Thakur
BACKGROUND: To evaluate the accuracy of high resolution ultrasound (USG) and MRI in the diagnosis of rotator cuff tears (RCT) and to determine if high resolution USG compares favorably in sensitivity and specificity to MRI in the diagnosis of rotator cuff injury. MATERIAL/METHODS: In this prospective comparative study, 40 patients with clinically suspected rotator cuff tears underwent both ultrasound and MRI of the shoulder. Out of these 40 patients, 31 patients who had positive findings for rotator cuff tears on ultrasound and/or MRI were finally included in the study while the remaining 9 patients with negative or unrelated findings were excluded...
2016: Polish Journal of Radiology
https://www.readbyqxmd.com/read/27792788/trem-1-hmgb1-and-rage-in-the-shoulder-tendon-dual-mechanisms-for-inflammation-based-on-the-coincidence-of-glenohumeral-arthritis
#16
Finosh G Thankam, Matthew F Dilisio, Nicholas E Dietz, Devendra K Agrawal
Rotator cuff injury (RCI) is a major musculoskeletal disorder in the adult population where inflammation and pain are major contributing factors. Coincidence of other clinical conditions like glenohumeral arthritis aggravates inflammation and delays the healing response. The mechanism and signaling factors underlying the sustenance of inflammation in the rotator cuff joint are largely unknown. The present article aims to elucidate the involvement of inflammatory molecule, TREM-1 (Triggering Receptors Expressed on Myeloid cells-1), and danger-associated molecular patterns (DAMPs), including high mobility group protein 1 (HMGB-1) and RAGE (receptor for advanced glycation end products), in the setting of RCI with respect to the severity of glenohumeral arthritis...
2016: PloS One
https://www.readbyqxmd.com/read/27792147/icariin-promotes-tendon-bone-healing-during-repair-of-rotator-cuff-tears-a-biomechanical-and-histological-study
#17
Chenyi Ye, Wei Zhang, Shengdong Wang, Shuai Jiang, Yuanbin Yu, Erman Chen, Deting Xue, Jianzhong Chen, Rongxin He
To investigate whether the systematic administration of icariin (ICA) promotes tendon-bone healing after rotator cuff reconstruction in vivo, a total of 64 male Sprague Dawley rats were used in a rotator cuff injury model and underwent rotator cuff reconstruction (bone tunnel suture fixation). Rats from the ICA group (n = 32) were gavage-fed daily with ICA at 0.125 mg/g, while rats in the control group (n = 32) received saline only. Micro-computed tomography, biomechanical tests, serum ELISA (calcium; Ca, alkaline phosphatase; AP, osteocalcin; OCN) and histological examinations (Safranin O and Fast Green staining, type I, II and III collagen (Col1, Col2, and Col3), CD31, and vascular endothelial growth factor (VEGF)) were analyzed two and four weeks after surgery...
October 25, 2016: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/27785555/clinical-and-radiologic-outcomes-of-arthroscopic-suture-bridge-repair-for-the-greater-tuberosity-fractures-of-the-proximal-humerus
#18
Jong-Hun Ji, Jae-Jung Jeong, Young-Yul Kim, Se-Won Lee, Do-Yeol Kim, Sang-Eun Park
PURPOSE: To report the clinical and radiological outcomes of arthroscopic suture bridge repair for the GT fractures of the shoulder joint. METHODS: From March 2008 to July 2013, we performed arthroscopic suture bridge repair of the GT fractures displaced more than 5 mm superiorly or posteriorly, but less than 2 cm in 40 cases [20 men, 20 women; mean age, 56 (27-80) years] with the average 32 (24-48) months follow-up. At the final follow-up, clinical (ASES, UCLA, SST, KSS score and range of motions) and radiological outcomes using post-operative MRI or CT scan were evaluated...
October 26, 2016: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/27773489/repair-of-rotator-cuff-injuries-using-different-composites
#19
Y Lopiz, C Arvinius, C García-Fernández, M C Rodriguez-Bobada, P González-López, A Civantos, F Marco
AIM: Rotator cuff repairs have shown a high level of re-ruptures. It is hypothesised that the use of rhBMP-2 in a carrier could improve the biomechanical and histological properties of the repair. MATERIAL AND METHODS: Controlled experimental study conducted on 40 rats with section and repair of the supraspinatus tendon and randomisation to one of five groups: Group 1 (control) only suture; Group 2 (double control), suture and alginate-chitin carrier; Group 3 (alginate-control), the rhBMP-2 was added to the alginate; Group 4 (chitin-control) application of the rhBMP-2 to the chitin, and Group 5 (double sample): The two components of the carrier (alginate and chitin) have rhBMP-2...
October 20, 2016: Revista Española de Cirugía Ortopédica y Traumatología
https://www.readbyqxmd.com/read/27768610/biologic-and-synthetic-grafts-in-the-reconstruction-of-large-to-massive-rotator-cuff-tears
#20
Robert J Gillespie, Derrick M Knapik, Ozan Akkus
Rotator cuff injuries are common in both young and elderly patients. Despite improvements in instrumentation and surgical techniques, the failure rates following tendon reconstruction remain unacceptably high. To improve outcomes, graft patches have been developed to provide mechanical strength and to furnish a scaffold for biologic growth across the delicate tendon-bone junction. Although no patch effectively re-creates the structured, highly organized system of prenatal tendon development, augmenting rotator cuff repair may help restore native tendon-to-bone attachment while reproducing the mechanical and biologic properties of native tendon...
December 2016: Journal of the American Academy of Orthopaedic Surgeons
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