keyword
https://read.qxmd.com/read/38442491/validation-of-cell-free-protein-synthesis-aboard-the-international-space-station
#21
JOURNAL ARTICLE
Selin Kocalar, Bess M Miller, Ally Huang, Emily Gleason, Kathryn Martin, Kevin Foley, D Scott Copeland, Michael C Jewett, Ezequiel Alvarez Saavedra, Sebastian Kraves
Cell-free protein synthesis (CFPS) is a rapidly maturing in vitro gene expression platform that can be used to transcribe and translate nucleic acids at the point of need, enabling on-demand synthesis of peptide-based vaccines and biotherapeutics as well as the development of diagnostic tests for environmental contaminants and infectious agents. Unlike traditional cell-based systems, CFPS platforms do not require the maintenance of living cells and can be deployed with minimal equipment; therefore, they hold promise for applications in low-resource contexts, including spaceflight...
March 5, 2024: ACS Synthetic Biology
https://read.qxmd.com/read/38422505/applying-tension-to-the-transcervical-foley-balloon-and-delivery-times-in-term-nulliparous-women-undergoing-induction-of-labor-a-randomized-controlled-trial
#22
JOURNAL ARTICLE
Meagan Benson, Lena Younes, Alisha Watson, George R Saade, Antonio F Saad
OBJECTIVE: To investigate the effects of applying tension to a transcervical Foley balloon on delivery time in term nulliparous patients undergoing labor induction. METHODS: This cluster randomized clinical trial included 279 term nulliparous women presenting for labor induction with a plan for cervical ripening through transcervical Foley balloon placement. Participants were assigned to either the tension group (n=138) or the no-tension group (n=141) on the basis of randomized, weekly clusters (26 total clusters)...
February 29, 2024: Obstetrics and Gynecology
https://read.qxmd.com/read/38406696/digital-app-reshaping-cardiac-rehabilitation-a-pilot-study
#23
JOURNAL ARTICLE
Jagvi Patel, Hernani Almeida, Sharifah Zeynah Alhadad, Alexandra Cardoso Pinto, Michael Foley, Rasha Al-Lamee
No abstract text is available yet for this article.
November 2023: Future Healthcare Journal
https://read.qxmd.com/read/38403107/unification-and-orificing-of-two-functional-noncommunicating-uterine-horns-through-the-created-neovagina-using-peritoneum
#24
JOURNAL ARTICLE
Gurkan Uncu, Isil Kasapoglu, Kiper Aslan
OBJECTIVE: To demonstrate the surgical approach for Müllerian agenesis with bilateral uterine remnants containing functional endometrium. DESIGN: Stepwise demonstration of the technique with narrated video footage. SETTING: Reproductive surgery unit of a tertiary university hospital. PATIENT: An 18-year-old adolescent was admitted to a tertiary university hospital with complaints of primary amenorrhea and cyclic pelvic pain...
February 23, 2024: Fertility and Sterility
https://read.qxmd.com/read/38402482/2023-2024-american-board-of-orthodontics-practice-analysis-study-part-1
#25
JOURNAL ARTICLE
Timothy S Trulove, Jae Hyun Park, Roberto Hernandez-Orsini, P Emile Rossouw, Anthony M Puntillo, Daniel J Rejman, Meenakshi Vishwanath, Onur Kadioglu, Patrick F Foley
As a specialty board, the American Board of Orthodontics (ABO) serves to protect the public and the orthodontic specialty by certifying orthodontists. The demonstration of commitment to lifelong learning and self-improvement is critical to achieving the highest level of patient care. The ABO completed a practice analysis study in 2023 to ensure all examinations represent current assessments of proficiency in orthodontics at a level of quality that satisfies professional expectations. The practice analysis is essential to providing a demonstrable relationship between the examination content and orthodontic practice and provides a critical foundation for ABO's examination programs...
February 22, 2024: American Journal of Orthodontics and Dentofacial Orthopedics
https://read.qxmd.com/read/38401032/urinary-catheter-placement-and-adverse-urinary-outcomes-with-a-focus-on-elevated-risk-in-men-with-indwelling-foley-catheters
#26
JOURNAL ARTICLE
Kai-Ting Chang, Po-Husan Lai, I-Cheng Lu, Ru-Yi Huang, Chi-Wei Lin, Chi-Hsien Huang
BACKGROUND: Prior studies indicated a link between urinary catheter use and urinary complications, highlighting the need for comprehensive, gender-specific investigations. This study explored the association through a national retrospective cohort, emphasizing gender disparities and long-term outcomes. METHODS: Our study utilized data from the entire population covered by Taiwan's National Health Insurance Research Database from 2000 to 2017. We included 148,304 patients who had undergone Foley catheter placement and their propensity-scores matched controls in the study...
February 24, 2024: Journal of the American Geriatrics Society
https://read.qxmd.com/read/38383963/analysis-of-15%C3%A2-000-solid-organ-transplant-recipients-reveals-nonanal-genitourinary-hpv-related-disease-as-highest-risk-predictor-for-anal-squamous-intraepithelial-lesions-anal-cancer
#27
JOURNAL ARTICLE
Matthew J Freeman, Qiuyu Yang, Linda Cherney-Stafford, Rob Striker, David P Foley, David P Al-Adra, Cristina B Sanger
BACKGROUND: Solid organ transplantation is a risk predictor for virally-mediated anal squamous intraepithelial lesions and cancer (anal disease). Precancerous squamous intraepithelial lesions can be detected by screening, and treatment may prevent cancer progression. Screening recommendations are not well defined. We aim to define prevalence and describe risk predictors for anal disease in a large population of solid organ transplant recipients. METHODS: Retrospective single-center cohort analysis included solid organ transplant recipients cared for between 2001 and 2022 (N = 15 362)...
February 22, 2024: Transplantation
https://read.qxmd.com/read/38365820/multilevel-approaches-to-address-disparities-in-lung-cancer-screening-a-study-protocol
#28
JOURNAL ARTICLE
Randi M Williams, Julia Whealan, Kathryn L Taylor, Lucile Adams-Campbell, Kristen E Miller, Kristie Foley, George Luta, Heather Brandt, Katharine Glassmeyer, Anu Sangraula, Peyton Yee, Kaylin Camidge, Joseph Blumenthal, Saumil Modi, Heather Kratz
BACKGROUND: Low-dose computed tomography (lung cancer screening) can reduce lung cancer-specific mortality by 20-24%. Based on this evidence, the United States Preventive Services Task Force recommends annual lung cancer screening for asymptomatic high-risk individuals. Despite this recommendation, utilization is low (3-20%). Lung cancer screening may be particularly beneficial for African American patients because they are more likely to have advanced disease, lower survival, and lower screening rates compared to White individuals...
February 16, 2024: Implementation science communications
https://read.qxmd.com/read/38365519/incidence-severity-and-characteristics-of-medical-device-related-pressure-injuries-in-adult-intensive-care-patients-a-single-centre-cross-sectional-study
#29
JOURNAL ARTICLE
Zeynep Temiz, Aylin Aydın Sayılan, Samet Sayılan, Esra Azum
AIM: This study aimed to determine the incidence, severity and characteristics of medical device-related pressure injuries in intensive care units. METHODS: This is a cross-sectional study. Data were collected from 187 patients admitted to the Anaesthesia and Reanimation intensive care unit of a university hospital between January and May 2023. The skin of the patients enrolled in the study was assessed for the presence of medical device-related pressure injuries, and all medical devices used were recorded...
February 13, 2024: Journal of Tissue Viability
https://read.qxmd.com/read/38358893/clinical-immunohistochemical-and-genetic-characterization-of-splice-altering-biallelic-des-variants-therapeutic-implications
#30
JOURNAL ARTICLE
Janelle Geist Hauserman, Chamindra G Laverty, Sandra Donkervoort, Ying Hu, Sarah Silverstein, Sarah B Neuhaus, Dimah Saade, Gabrielle Vaughn, Denise Malicki, Rupleen Kaur, Yuesheng Li, Yan Luo, Poching Liu, Patrick Burr, A Reghan Foley, Payam Mohassel, Carsten G Bönnemann
Pathogenic variants in the DES gene clinically manifest as progressive skeletal muscle weakness, cardiomyopathy with associated severe arrhythmias, and respiratory insufficiency, and are collectively known as desminopathies. While most DES pathogenic variants act via a dominant mechanism, recessively acting variants have also been reported. Currently, there are no effective therapeutic interventions for desminopathies of any type. Here, we report an affected individual with rapidly progressive dilated cardiomyopathy, requiring heart transplantation at age 13 years, in the setting of childhood-onset skeletal muscle weakness...
February 2, 2024: HGG advances
https://read.qxmd.com/read/38357040/tube-stoma-for-the-management-of-ileocolic-anastomotic-leak-in-a-patient-with-metastatic-colon-cancer
#31
Mohammed I Elsayed
This case involves a 53-year-old male who was diagnosed with stenotic ascending colon cancer and peritoneal metastatic deposits. He was initially planned for cytoreductive surgery and heated intraperitoneal chemotherapy (CRS and HIPEC), along with resection of the primary tumor in the form of right hemicolectomy. Intraoperatively, the disease was found to be more extensive than anticipated. Consequently, the plan was modified to include debulking right hemicolectomy with hand-sewn ileocolic anastomosis and extensive peritoneal procedures...
January 2024: Curēus
https://read.qxmd.com/read/38351634/-hearts-and-minds-illustrating-identity-tensions-of-people-living-and-working-through-marketising-policy-change-of-allied-health-disability-services-in-australia
#32
JOURNAL ARTICLE
Kristen Foley, Stacie Attrill, Chris Brebner
Service-based caring sectors like disability are increasingly being operated via market logic, including shifts towards personalised funding. These shifts must be brought to life in/through people already located in relation to ideas and values that underpin historical policies. Our manuscript examines how identities are re/shaped in relation to marketised policy change and explores how identity change unfolds (or not) during periods of transition: situated within the transition to the National Disability Insurance Scheme executed in Australia as a major disability funding reform...
February 13, 2024: Health (London)
https://read.qxmd.com/read/38336174/self-bladder-emptying-compared-with-foley-catheter-placement-for-planned-cesarean-section-a-randomized-controlled-trial
#33
JOURNAL ARTICLE
Nabila Arfah Mohd Yassin, Maherah Kamarudin, Mukhri Hamdan, Peng Chiong Tan
BACKGROUND: The global cesarean delivery rate is high and continuing to increase. A bladder catheter is usually placed for the cesarean section as a distended bladder is assumed to be at higher risk of injury during surgery and to compromise surgical field exposure. Preliminary data suggest that self-bladder emptying (no catheter) at cesarean delivery may have advantages and be safe. OBJECTIVE: To evaluate self-bladder emptying to indwelling foley bladder catheterization for a planned cesarean on rate of postpartum urinary retention and maternal satisfaction...
February 7, 2024: American journal of obstetrics & gynecology MFM
https://read.qxmd.com/read/38335098/resilience-and-burnout-of-healthcare-workers-during-the-early-covid-19-pandemic
#34
JOURNAL ARTICLE
Haleema Siddique, Robert Munashe Maweni, Micol Lupi, Shannan Woods, Shahram Shirazi, Robert William Foley, Debra Machando
INTRODUCTION: The COVID-19 pandemic has led to significantly more healthcare workers (HCWs) experiencing burnout than previously. This burnout is strongly associated with low resilience. Addressing organisational stresses and the introduction of resilience training will help to reduce the proportion of HCWs experiencing this phenomenon. AIMS: The aim of this study was to assess the impact of the biopsychosocial changes and challenges associated with the COVID-19 pandemic on the healthcare workforce, exploring, specifically, the impact on and relationship between HCWs' resilience and burnout...
February 8, 2024: British Journal of Nursing: BJN
https://read.qxmd.com/read/38325582/evaluation-and-resection-of-a-longitudinal-vaginal-septum-in-an-adult
#35
JOURNAL ARTICLE
Bertie Geng, Brad St Martin, Oz Harmanli
OBJECTIVE: The objective of this video is to demonstrate the diagnosis, evaluation, and techniques for surgical management of a longitudinal vaginal septum, a rare Mullerian anomaly. DESIGN: This is a stepwise demonstration of evaluation and surgical techniques with video narration. SETTING: The incidence of Mullerian defects, which can include any anomaly in the fallopian tube, uterus, cervix, or vagina, has been estimated to be 2-4%.1 30-40% of patients with Mullerian defects also have associated renal anomalies...
February 5, 2024: Journal of Minimally Invasive Gynecology
https://read.qxmd.com/read/38309980/invasive-fungus-balls-diagnosed-by-point-of-care-ultrasound-in-the-emergency-department
#36
JOURNAL ARTICLE
Sean Beckman, Rebecca Goett, Bianca Yugar, Stephen Alerhand
BACKGROUND: Genitourinary tract fungus balls are a rare complication of urinary tract infections (UTI). They arise from dense aggregations of hyphae that combine with surrounding urothelial cells and debris. Symptoms can progress to urosepsis and systemic dissemination. Unfortunately, fungus balls may remain unrecognized. Even with computed tomography (CT) and magnetic resonance imaging, fungus balls can be mistaken for malignancies, urinary calculi, or blood clots. CASE REPORT: A 54-year-old man with past medical history of type 2 diabetes mellitus presented to the Emergency Department (ED) reporting urinary retention for one week...
November 4, 2023: Journal of Emergency Medicine
https://read.qxmd.com/read/38306291/evidence-based-management-of-labor
#37
JOURNAL ARTICLE
Linda M Zambrano Guevara, Caledonia Buckheit, Jeffrey A Kuller, Beverly Gray, Sarah Dotters-Katz
IMPORTANCE: Induction of labor (IOL) is a common obstetric intervention. Augmentation of labor and active management of the second stage is frequently required in obstetric practice. However, techniques around labor and induction management vary widely. Evidence-based practice regarding induction and labor management can reduce birth complications such as infection and hemorrhage and decrease rates of cesarean delivery. OBJECTIVE: To review existing evidence on IOL and labor management strategies with respect to preparing for induction, cervical ripening, induction and augmentation, and second stage of labor techniques...
January 2024: Obstetrical & Gynecological Survey
https://read.qxmd.com/read/38299538/occupational-therapists-assessment-and-reporting-of-functional-cognition-in-stroke-care
#38
JOURNAL ARTICLE
Jana Ward, Geraldine Foley, Frances Horgan
PURPOSE: To investigate how functional cognition of people post-stroke is evaluated and reported by occupational therapists in Ireland. Functional cognition refers to the use and integration of cognitive skills for daily function. METHODS: This study used a qualitative design. Six focus groups and one individual interview were conducted with 20 occupational therapists purposively sampled for variation across different clinical grades. Data were analysed according to the Braun and Clark thematic analysis framework...
February 1, 2024: Disability and Rehabilitation
https://read.qxmd.com/read/38284498/the-effectiveness-of-preoperative-delirium-prevention-in-intermediate-to-high-risk-older-surgical-patients-a-systematic-review
#39
REVIEW
Nicholas Lay, Pieternella Foley, Jacqueline Allen
BACKGROUND: Few reviews have addressed delirium prevention among intermediate to high-risk older surgical patients. AIMS: To map preoperative delirium prevention interventions for older surgical patients at intermediate to high risk of developing delirium, assess outcomes and identify gaps in knowledge. DESIGN: Systematic narrative review of randomised controlled trials reported following the PRISMA checklist. METHODS: A systematic search was conducted of the literature published from 1990 to October 2022 in Medline, CINAHL and Ageline and of the grey literature in Google Scholar...
January 29, 2024: Journal of Clinical Nursing
https://read.qxmd.com/read/38273319/plus-is-less-project-procalcitonin-and-lung-ultrasonography-based-antibiotherapy-in-patients-with-lower-respiratory-tract-infection-in-swiss-emergency-departments-study-protocol-for-a-pragmatic-stepped-wedge-cluster-randomized-trial
#40
JOURNAL ARTICLE
Cécile Bessat, Roland Bingisser, Markus Schwendinger, Tim Bulaty, Yvan Fournier, Vincent Della Santa, Magali Pfeil, Dominique Schwab, Jörg D Leuppi, Nicolas Geigy, Stephan Steuer, Friedemann Roos, Michael Christ, Adriana Sirova, Tanguy Espejo, Henk Riedel, Alexandra Atzl, Fabian Napieralski, Joachim Marti, Giulio Cisco, Rose-Anna Foley, Melinée Schindler, Mary-Anne Hartley, Aurélie Fayet, Elena Garcia, Isabella Locatelli, Werner C Albrich, Olivier Hugli, Noémie Boillat-Blanco
BACKGROUND: Lower respiratory tract infections (LRTIs) are among the most frequent infections and a significant contributor to inappropriate antibiotic prescription. Currently, no single diagnostic tool can reliably identify bacterial pneumonia. We thus evaluate a multimodal approach based on a clinical score, lung ultrasound (LUS), and the inflammatory biomarker, procalcitonin (PCT) to guide prescription of antibiotics. LUS outperforms chest X-ray in the identification of pneumonia, while PCT is known to be elevated in bacterial and/or severe infections...
January 25, 2024: Trials
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