Read by QxMD icon Read

Benefit analysis

Jonathan J Stone, Jennifer M Boland, Robert J Spinner
INTRODUCTION: Using proper surgical technique, schwannomas can be resected safely, with a low recurrence rate and high likelihood of improvement in symptomatology. There are multiple peritumoral tissue layers and finding the correct plane is critical to safe tumor enucleation. The contents of the pseudocapsule tissue surrounding a schwannoma are not well described and the consequences of resecting or leaving pseudocapsule are unknown. METHODS: An institutional database was searched for any pathology reports that contained both of the words "schwannoma" and "capsule"...
August 13, 2018: World Neurosurgery
Xiao-Bin Huang, Wen-Wen Zhang, San-Gang Wu, Jia-Yuan Sun, Zhen-Yu He, Juan Zhou
BACKGROUND AND OBJECTIVES: To determine the survival benefits of additional adjuvant hysterectomy in the International Federation of Gynecology and Obstetrics (FIGO) stage I-II cervical adenocarcinoma patients treated with radiochemotherapy. METHODS: Patients with FIGO stage I-II cervical adenocarcinoma were selected from the Surveillance, Epidemiology, and End Results 18 Regs research database. Propensity score matching (PSM) was used to balance patient baseline characteristics...
August 16, 2018: Journal of Surgical Oncology
Mary Dillon, Louisa Flander, Daniel D Buchanan, Finlay A Macrae, Jon D Emery, Ingrid M Winship, Alex Boussioutas, Graham G Giles, John L Hopper, Mark A Jenkins, Driss Ait Ouakrim
BACKGROUND: The Australian National Bowel Cancer Screening Programme (NBCSP) was introduced in 2006. When fully implemented, the programme will invite people aged 50 to 74 to complete an immunochemical faecal occult blood test (iFOBT) every 2 years. METHODS AND FINDINGS: To investigate colorectal cancer (CRC) screening occurring outside of the NBCSP, we classified participants (n = 2,480) in the Australasian Colorectal Cancer Family Registry (ACCFR) into 3 risk categories (average, moderately increased, and potentially high) based on CRC family history and assessed their screening practices according to national guidelines...
August 2018: PLoS Medicine
Jens G Brockmann, Amir Butt, Hussa F Al Hussaini, Hadeel AlMana, Khaled AlSaad, Moheeb Al-Awwami, Dieter C Broering, Tariq Ali
BACKGROUND: Histological evaluation of the pancreas graft is usually done on demand resulting in significant delays. This analysis reports on endoscopic protocol duodenal graft biopsies at regular intervals to determine feasibility, safety and monitoring benefits. METHODS: Protocol duodenal graft biopsies in 27 18 consecutive pancreas transplants (10 simultaneous pancreas kidney [SPK], 17 pancreas after kidney [PAK]) with a follow-up of a minimum of 12 months were performed at days 14, 30, 90, 180, 360, 430...
August 15, 2018: Transplantation
Linda Bale, Catharine Jenkins
BACKGROUND: Nursing students and registered nurses often feel underprepared for their roles in dementia care. Extracurricular activities offer nursing students additional opportunities for professional development. A student-academic partnership initiative was developed in which nursing students delivered dementia friends sessions to their peers before formal taught content. AIM: To explore dementia champion nursing students' experiences, identify factors that affect collaborative working and make recommendations for future student-academic partnership projects...
August 16, 2018: Nursing Older People
Pai-Feng Hsu, Shih-Hsien Sung, Hao-Min Cheng, Shyi-Jang Shin, Kun-Der Lin, Keong Chong, Fu-Shun Yen, Ben-Hui Yu, Chi-Ting Huang, Chih-Cheng Hsu
Context: Althoughα-glucosidase inhibitor (AGI) has been shown to reduce the risk of myocardial infarction in patients with impaired glucose tolerance (IGT), the cardiovascular benefits of AGI in type 2 diabetes (T2D) remains unclear. Objective: We aimed to compare clinical outcomes of adding acarbose versus sulfonylureas to metformin therapy in T2D patients. Design, Setting, and Participants: The study population was drawn from the database of the Diabetes Pay-for-Performance (P4P) Program in Taiwan...
August 2, 2018: Journal of Clinical Endocrinology and Metabolism
Jason Pui Yin Cheung, Prudence Wing Hang Cheung, Karlen Law, Vishal Borse, Yuk Ming Lau, Ling Fung Mak, Aldous Cheng, Dino Samartzis, Kenneth Man Chee Cheung
BACKGROUND: Cervical collars are used after laminoplasty to protect the hinge opening, reduce risks of hinge fractures, and avoid spring-back phenomena. However, their use may lead to reduced range of motion and worse neck pain. OBJECTIVE: To investigate the clinical, radiological, and functional outcomes of patients undergoing single-door laminoplasty with or without collar immobilization. METHODS: This was a prospective, parallel, single-blinded randomized controlled trial...
August 3, 2018: Neurosurgery
Rosa Silva, Sérgio Abrunheiro, Daniela Cardoso, Paulo Costa, Filipa Couto, Cátia Agrenha, João Apóstolo
OBJECTIVE: The objective of the review was to synthesize the effectiveness of multisensory stimulation in managing neuropsychiatric symptoms (NPS) in older adults with major neurocognitive disorder (NCD). INTRODUCTION: Major neurocognitive disorder is characterized by changes in specific cognitive domains with a progressive deterioration in cognitive ability and capacity for independent living. Most older adults with this condition have one or more concomitant symptoms known as NPS...
August 2018: JBI Database of Systematic Reviews and Implementation Reports
Alexander C Reynolds, Nicola King
BACKGROUND: Hybrid coronary revascularization (HCR) combining minimally invasive grafting of the left internal mammary artery to the left anterior descending artery with percutaneous coronary intervention has become a viable option for treating coronary artery disease. The aim of this meta-analysis was to compare HCR with conventional coronary artery bypass grafting (CABG) in a range of clinical outcomes and hospital costs. METHODS: To identify potential studies, systematic searches were carried out in various databases...
August 2018: Medicine (Baltimore)
Jie-Yu Kong, Shu-Mei Li, Hai-Yan Fan, Lan Zhang, Hui-Jin Zhao, Sheng-Mian Li
The long-term survival benefit of treating unresectable hepatocellular carcinoma (HCC) patients with transarterial chemoembolization (TACE) rather than conservative treatment remains controversial. This retrospective case-control study evaluated the survival of patients with unresectable HCC treated with TACE, relative to that of patients who received best supportive care.From January 2002 to December 2010, 522 of 2386 consecutive patients with unresectable HCC were enrolled. Patients were treated with TACE (n = 347) or best supportive care (non-TACE; n = 175)...
August 2018: Medicine (Baltimore)
Shuai Qie, Yanhong Li, Hong-Yun Shi, Lanhui Yuan, Lei Su, Xi Zhang
BACKGROUND: The present study aims to assess the therapeutic effect of whole brain radiotherapy (WBRT) for brain metastases from non-small cell lung cancer stratified by graded prognostic assessment (GPA) through meta-analysis. METHODS: The Cochrane Library, PubMed, Ovid (Elsevier) were retrieved. The included randomized controlled trials (RCT) were evaluated, and the statistical analysis was performed using RevMan 5.3 software. Cochrane handbook was applied to evaluate the methodological quality...
August 2018: Medicine (Baltimore)
Jerry John Nutor, Jaime C Slaughter-Acey, Carmen Giurgescu, Dawn P Misra
OBJECTIVE: To investigate the relationship between depressive symptoms and preterm birth (PTB) while adjusting for social support, both general and from the father of the baby. DESIGN: Retrospective study design. SETTING: Participants of the Life-course Influences of Fetal Environments (LIFE) study were recruited from a suburban hospital in Metropolitan Detroit, Michigan. PARTICIPANTS: The LIFE data consisted of 1,410 self-identified Black women age 18 to 45 years; 1,207 women were included in this analysis...
September 2018: MCN. the American Journal of Maternal Child Nursing
Duncan S Buchan, Gareth Knox, Anwen M Jones, Grant R Tomkinson, Julien S Baker
The purpose of this study was to examine the ability of international normative centiles for the 20 m shuttle run test (20mSRT) to identify youth at increased cardiometabolic risk. This was a cross-sectional study involving 961 children aged 10-17 years (53% girls) from the United Kingdom. Receiver operating characteristic (ROC) curves determined the discriminatory ability of cardiorespiratory fitness percentiles for predicting increased cardiometabolic risk. ROC analysis demonstrated a significant but poor discriminatory accuracy of cardiorespiratory fitness in identifying low/high cardiometabolic risk in girls (AUC = 0...
August 16, 2018: Journal of Sports Sciences
Naista Zhand, Robert Milin
BACKGROUND AND OBJECTIVES: Sleep disturbance is one of the hallmarks of cannabis withdrawal. Studies have indicated that treatment of this key symptom may facilitate abstinence. In the present paper we aim to provide a systematic review of the extant literature on pharmacological management of sleep disturbance associated with cannabis withdrawal. METHOD: We conducted a systematic literature search across five electronic databases including PubMed, Psycinfo, MEDLINE, Cochrane review and Embase...
August 16, 2018: American Journal on Addictions
Yash D Mehta, Yogendra Shastri, Babu Joseph
Municipal solid waste (MSW) management is a major concern in Indian cities. This work rigorously assesses the relative costs and the environmental and health benefits of alternative MSW management methods. Management of MSW over the next 20 years for the city of Greater Mumbai was considered. A generic model was developed to determine the costs for (i) dumping on open ground, (ii) sanitary landfill without leachate treatment, (iii) landfilling with leachate treatment and (iv) regional composting and landfilling...
August 16, 2018: Waste Management & Research
Fabio Bagante, Faiz Gani, Eliza W Beal, Katiuscha Merath, Qinyu Chen, Mary Dillhoff, Jordan Cloyd, Timothy M Pawlik
BACKGROUND: The National Comprehensive Cancer Network (NCCN) guidelines recommend chemotherapy for patients with inoperable biliary tract cancers (BTC), as well as patients following resection of BTC with lymph node metastasis (N1)/positive margins (R1). We sought to define overall adherence, as well as long-term outcomes, with the NCCN guidelines for BTC using the National Cancer Database (NCDB). METHODS: A total of 176,536 patients diagnosed with BTC at a hospital participating in the NCDB between 2004 and 2015 were identified...
August 15, 2018: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
Mosaad A Abdel-Wahhab, Aziza A El-Nekeety, Nabila S Hassan, Abdullah A Y Gibriel, Khaled G Abdel-Wahhab
Fumonisin B1 (FB1 ) and aflatoxin B1 (AFB1 ) are fungal metabolites that frequently co-occur in foodstuffs and are responsible for mycotoxicosis and several primary cancers. Cinnamon essential oil (CEO) has a spacious range of benefit effects but also has some limitations owing to its strong taste or its interaction with some drugs. This study aimed to use the cinnamon oil emulsion droplets (COED) for the protection against oxidative stress, cytotoxicity, and reproductive toxicity in male Sprague-Dawley rats sub-chronically exposed to FB1 and/or AFB1 ...
August 15, 2018: Environmental Science and Pollution Research International
Damien Bergeat, Olivier Turrini, Laetitia Courtin-Tanguy, Stéphanie Truant, Benjamin Darnis, Jean Robert Delpero, Jean-Yves Mabrut, Nicolas Regenet, Laurent Sulpice
BACKGROUND: The benefit of adjuvant chemotherapy (AC) after pancreaticoduodenectomy (PD) for distal cholangiocarcinoma (DCC) remains controversial. The study aimed to evaluate the impact of AC after PD for DCC in a large multicentric cohort. METHODS: Patients from five French centers who underwent from PD for DCC between 2000 and 2015 and received AC (AC+ group) or surgery only (AC- group) were included in the analysis. Variables associated with AC administration were analyzed by univariate analysis...
August 15, 2018: Langenbeck's Archives of Surgery
G Klarenberg, R Muñoz-Carpena, M A Campo-Bescós, S G Perz
Infrastructure development, specifically road paving, contributes socio-economic benefits to society worldwide. However, detrimental environmental effects of road paving have been documented, most notably increased deforestation. Beyond deforestation, we hypothesize that road paving introduces "unseen" regional scale effects on forests, due to changes to vegetation dynamics. To test this hypothesis, we focus on the tri-national frontier in the southwestern Amazon that has been subject to construction of the Inter-Oceanic Highway (IOH) between 1987 and 2010...
August 2018: Heliyon
Leonardo do Prado Lima, Carla Jorge Machado, João Bernardo Sancio Rocha Rodrigues, Leonardo de Souza Vasconcellos, Eduardo Paulino Junior, Paula Vieira Teixeira Vidigal, Vivian Resende
Background and Aim: The epithelial cell adhesion molecule (EpCAM) has been proposed as a marker for cancer stem cells in human hepatocellular carcinoma (HCC) as well as in the development of novel target therapies. This study aimed to investigate the immunohistochemical expression of EpCAM and alpha-fetoprotein (AFP) in HCC patients and their association with clinicopathological characteristics. Methods: This study included Child-Pugh A HCC patients undergoing curative surgical resection...
2018: Canadian Journal of Gastroenterology & Hepatology
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"