keyword
MENU ▼
Read by QxMD icon Read
search

Breast volume measurement

keyword
https://www.readbyqxmd.com/read/27908586/standard-wide-local-excision-or-bilateral-reduction-mammoplasty-in-large-breasted-women-with-small-tumours-surgical-and-patient-reported-outcomes
#1
R Di Micco, R L O'Connell, P A Barry, N Roche, F A MacNeill, J E Rusby
INTRODUCTION: Oncoplastic breast surgery is used to extend the role of breast-conserving surgery (BCS) to women with an unfavourable tumour to breast volume ratio. However, large-breasted women with a relatively small breast cancer may be offered bilateral reduction mammoplasty (BRM) despite being suitable for standard BCS as the more complex surgery may have advantages in terms of patient satisfaction and reduced adverse effects of radiotherapy. PATIENT AND METHODS: This retrospective study evaluated surgical and patient-reported outcome measures (PROMs) in large-breasted women with early (<3 cm) breast cancer, who have undergone unilateral standard BCS or BRM...
November 17, 2016: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27903677/combined-inhibition-of-both-p110%C3%AE-and-p110%C3%AE-isoforms-of-phosphatidylinositol-3-kinase-is-required-for-sustained-therapeutic-effect-in-pten-deficient-er-breast-cancer
#2
Sarah R Hosford, Lloye M Dillon, Stephanie J Bouley, Rachele Rosati, Wei Yang, Vivian S Chen, Eugene Demidenko, Rocco P Morra, Todd W Miller
PURPOSE: Determine the roles of the phosphatidylinositol 3-kinase (PI3K) isoforms p110α and p110β in PTEN-deficient, estrogen receptor α (ER)-positive breast cancer, and the therapeutic potential of isoform-selective inhibitors. EXPERIMENTAL DESIGN: Anti-estrogen-sensitive and -resistant PTEN-deficient, ER+ human breast cancer cell lines, and mice bearing anti-estrogen-resistant xenografts were treated with the anti-estrogen fulvestrant, the p110α inhibitor BYL719, the p110β inhibitor GSK2636771, or combinations...
November 30, 2016: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/27895746/rnai-mediated-gene-silencing-of-vascular-endothelial-growth-factor-c-suppresses-growth-and-induces-apoptosis-in-mouse-breast-cancer-in-vitro-and-in-vivo
#3
Yong-Chao Liu, Wen-Hui Ma, Yin-Lin Ge, Mei-Lan Xue, Zheng Zhang, Jin-Yu Zhang, Lin Hou, Run-Hong Mu
Vascular endothelial cell growth factor (VEGF)-C promotes tumorigenesis by allowing lymph node metastasis and lymphangiogenesis, among other actions. RNA interference (RNAi) is a novel technique for suppressing target gene expression and may increase the effectiveness of cancer treatments. The present study assessed the influence of VEGF-C RNAi on the apoptosis and proliferation of mouse breast cancer cells in vitro and in vivo. A total of three pairs of small interfering RNA (siRNA) targeting mouse VEGF-C were designed and synthesized prior to transfection into 4T1 cells via a liposomal approach...
November 2016: Oncology Letters
https://www.readbyqxmd.com/read/27893532/the-effect-of-hospital-volume-on-breast-cancer-mortality
#4
Rachel A Greenup, Samilia Obeng-Gyasi, Samantha Thomas, K Houck, Whitney O Lane, Rachel C Blitzblau, Terry Hyslop, E Shelley Hwang
OBJECTIVE: The aim of this study was to determine whether hospital volume was associated with mortality in breast cancer, and what thresholds of case volume impacted survival. BACKGROUND: Prior literature has demonstrated improved survival with treatment at high volume centers among less common cancers requiring technically complex surgery. METHODS: All adults (18 to 90 years) with stages 0-III unilateral breast cancer diagnosed from 2004 to 2012 were identified from the American College of Surgeons National Cancer Data Base (NCDB)...
November 23, 2016: Annals of Surgery
https://www.readbyqxmd.com/read/27892665/thyroid-function-after-postoperative-radiation-therapy-in-patients-with-breast-cancer
#5
Edyta Wolny-Rokicka, Andrzej Tukiendorf, Jerzy Wydmański, Danuta Roszkowska, Bogusław Staniul, Agnieszka Zembroń-Łacny
Objective: The aim of this study was to assess thyroid function in breast cancer patients exposed to therapeutic external beam radiation. The focus was on possible progressive changes and any relationships between the incidence of primary hypothyroidism, the time required to become hypothyroid, and factors such as chemotherapy, hormonotherapy and immunotherapy. Materials and Methods: Seventy females undergoing 3D conformal and IMRT radiation therapy for breast cancers were enrolled in a non-randomized prospective study...
January 10, 2016: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/27888545/anti-angiogenic-therapy-affects-the-relationship-between-tumor-vascular-structure-and-function-a-correlation-study-between-micro-computed-tomography-angiography-and-dynamic-contrast-enhanced-mri
#6
Eugene Kim, Jana Kim, Gunhild Mari Maelandsmo, Berit Johansen, Siver Andreas Moestue
PURPOSE: To compare the effects of two anti-angiogenic drugs, bevacizumab and a cytosolic phospholipase A2-α inhibitor (AVX235), on the relationship between vascular structure and dynamic contrast enhanced (DCE)-MRI measurements in a patient-derived breast cancer xenograft model. METHODS: Mice bearing MAS98.12 tumors were randomized into three groups: bevacizumab-treated (n = 9), AVX235-treated (n = 9), and control (n = 8). DCE-MRI was performed pre- and post-treatment...
November 25, 2016: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/27879584/stacked-thoracodorsal-artery-perforator-flaps-for-unilateral-breast-reconstruction
#7
Claudio Angrigiani, Alberto Rancati, Guillermo Artero, Roger K Khouri, Frances M Walocko
The thoracodorsal artery perforator flap is reliable and safe for breast reconstruction, but stacking bilateral thoracodorsal artery perforator flaps for unilateral reconstruction to achieve greater volumes has not been reported. To create a stacked thoracodorsal artery perforator flap, the ipsilateral flap is transferred as an island, and the contralateral flap is transferred as a microvascular free flap. In this article, the authors present their 8-year 14- patient experience with stacked thoracodorsal artery perforator flaps for unilateral breast reconstruction...
December 2016: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/27873127/radiotherapy-induced-global-and-regional-differences-in-early-stage-left-sided-versus-right-sided-breast-cancer-patients-speckle-tracking-echocardiography-study
#8
Suvi Sirkku Tuohinen, Tanja Skyttä, Tuija Poutanen, Heini Huhtala, Vesa Virtanen, Pirkko-Liisa Kellokumpu-Lehtinen, Pekka Raatikainen
Radiotherapy (RT) to the thoracic region increases late cardiovascular morbidity and mortality. The impact of breast cancer laterality on cardiac function is largely unknown. The aim of this prospective study was to compare RT-induced changes in left-sided and right-sided breast cancer patients using speckle tracking echocardiography (STE). Sixty eligible patients with left-sided breast cancer and 20 with right-sided breast cancer without chemotherapy were evaluated prospectively before and early after RT. A comprehensive echocardiographic examination included three dimensional measurements and STE of the left ventricle (LV)...
November 21, 2016: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/27867715/changes-of-collagen-ultrastructure-in-breast-cancer-tissue-determined-by-second-harmonic-generation-double-stokes-mueller-polarimetric-microscopy
#9
Ahmad Golaraei, Lukas Kontenis, Richard Cisek, Danielle Tokarz, Susan J Done, Brian C Wilson, Virginijus Barzda
Second-harmonic generation (SHG) double Stokes-Mueller polarimetric microscopy is applied to study the alteration of collagen ultrastructure in a tissue microarray containing three pathological human breast cancer types with differently overexpressed estrogen receptor (ER), progesterone receptor (PgR), and human epidermal growth factor receptor 2 (HER2). Kleinman symmetry is experimentally validated in breast tissue for 1028 nm laser wavelength and it has been shown that measurements with only linearly polarized incoming and outgoing states can determine molecular nonlinear susceptibility tensor component ratio, average in-plane orientation of collagen fibers and degree of linear polarization of SHG...
October 1, 2016: Biomedical Optics Express
https://www.readbyqxmd.com/read/27864652/differences-in-mammographic-density-between-asian-and-caucasian-populations-a-comparative-analysis
#10
Nadia Rajaram, Shivaani Mariapun, Mikael Eriksson, Jose Tapia, Pui Yoke Kwan, Weang Kee Ho, Faizah Harun, Kartini Rahmat, Kamila Czene, Nur Aishah Mohd Taib, Per Hall, Soo Hwang Teo
PURPOSE: Mammographic density is a measurable and modifiable biomarker that is strongly and independently associated with breast cancer risk. Paradoxically, although Asian women have lower risk of breast cancer, studies of minority Asian women in predominantly Caucasian populations have found that Asian women have higher percent density. In this cross-sectional study, we compared the distribution of mammographic density for a matched cohort of Asian women from Malaysia and Caucasian women from Sweden, and determined if variations in mammographic density could be attributed to population differences in breast cancer risk factors...
November 18, 2016: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/27861746/effect-of-hospital-volume-on-processes-of-breast-cancer-care-a-national-cancer-data-base-study
#11
Tina W F Yen, Liliana E Pezzin, Jianing Li, Rodney Sparapani, Purushuttom W Laud, Ann B Nattinger
BACKGROUND: The purpose of this study was to examine variations in delivery of several breast cancer processes of care that are correlated with lower mortality and disease recurrence, and to determine the extent to which hospital volume explains this variation. METHODS: Women who were diagnosed with stage I-III unilateral breast cancer between 2007 and 2011 were identified within the National Cancer Database. Multiple logistic regression models were developed to determine whether hospital volume was independently associated with each of 10 individual process of care measures addressing diagnosis and treatment, and 2 composite measures assessing appropriateness of systemic treatment (chemotherapy and hormonal therapy) and locoregional treatment (margin status and radiation therapy)...
November 8, 2016: Cancer
https://www.readbyqxmd.com/read/27848050/sentinel-lymph-node-based-management-or-routine-axillary-clearance-five-year-outcomes-of-the-racs-sentinel-node-biopsy-versus-axillary-clearance-snac-1-trial-assessment-and-incidence-of-true-lymphedema
#12
Neil Wetzig, Peter Grantley Gill, David Espinoza, Rebecca Mister, Martin R Stockler, Val J Gebski, Owen A Ung, Ian Campbell, John Simes
PURPOSE: To determine whether the benefits of sentinel-node-based management (SNBM) over routine axillary clearance (RAC) persisted to 5 years. METHODS: A total of 1088 women with breast cancer less than 3 cm in diameter and clinically negative axillary nodes were randomized to SNBM with axillary clearance if the sentinel node was positive or RAC preceded by sentinel-node biopsy. The outcomes were: (1) objectively measured change in the volume of the operated and contralateral nonoperated arms; (2) the proportion with an increase in arm volume <15%; and (3) subjectively assessed arm morbidity for the domains swelling, symptoms, dysfunction, and disability...
November 15, 2016: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/27842506/is-alcohol-consumption-a-risk-factor-for-prostate-cancer-a-systematic-review-and-meta-analysis
#13
Jinhui Zhao, Tim Stockwell, Audra Roemer, Tanya Chikritzhs
BACKGROUND: Research on a possible causal association between alcohol consumption and risk of prostate cancer is inconclusive. Recent studies on associations between alcohol consumption and other health outcomes suggest these are influenced by drinker misclassification errors and other study quality characteristics. The influence of these factors on estimates of the relationship between alcohol consumption and prostate cancer has not been previously investigated. METHODS: PubMed and Web of Science searches were made for case-control and cohort studies of alcohol consumption and prostate cancer morbidity and mortality (ICD-10: C61) up to December 2014...
November 15, 2016: BMC Cancer
https://www.readbyqxmd.com/read/27832985/effects-of-raloxifene-against-letrozole-induced-bone-loss-in-chemically-induced-model-of-menopause-in-mice
#14
Abul Kalam, Sushama Talegaonkar, Divya Vohora
INTRODUCTION: The deleterious effects of letrozole, an aromatase inhibitor, used in the adjuvant treatment of breast cancer in postmenopausal women, on bone are well-documented and represent a major drawback to its clinical use. Raloxifene, a selective estrogen receptor modulator and a clinically approved anti-osteoporotic drug, has been recently demonstrated to be efficacious in women with breast cancer. The present study evaluated the effects of preventive and curative treatment with raloxifene on letrozole-induced alterations of bone microarchitecture and turnover markers in a chemically-induced menopause model in mice...
November 8, 2016: Molecular and Cellular Endocrinology
https://www.readbyqxmd.com/read/27832519/automatic-estimation-of-volumetric-breast-density-using-artificial-neural-network-based-calibration-of-full-field-digital-mammography-feasibility-on-japanese-women-with-and-without-breast-cancer
#15
Jeff Wang, Fumi Kato, Hiroko Yamashita, Motoi Baba, Yi Cui, Ruijiang Li, Noriko Oyama-Manabe, Hiroki Shirato
Breast cancer is the most common invasive cancer among women and its incidence is increasing. Risk assessment is valuable and recent methods are incorporating novel biomarkers such as mammographic density. Artificial neural networks (ANN) are adaptive algorithms capable of performing pattern-to-pattern learning and are well suited for medical applications. They are potentially useful for calibrating full-field digital mammography (FFDM) for quantitative analysis. This study uses ANN modeling to estimate volumetric breast density (VBD) from FFDM on Japanese women with and without breast cancer...
November 10, 2016: Journal of Digital Imaging: the Official Journal of the Society for Computer Applications in Radiology
https://www.readbyqxmd.com/read/27812678/atrial-function-in-patients-with-breast-cancer-after-treatment-with-anthracyclines
#16
Yalin Tolga Yaylali, Ahmet Saricopur, Mustafa Yurtdas, Hande Senol, Gamze Gokoz-Dogu
Background: Atrial electromechanical delay (EMD) is used to predict atrial fibrillation, measured by echocardiography. Objectives: The aim of this study was to assess atrial EMD and mechanical function after anthracycline-containing chemotherapy. Methods: Fifty-three patients with breast cancer (48 ± 8 years old) who received 240 mg/m2of Adriamycin, 2400 mg/m2 of cyclophosphamide, and 960 mg/m2 of paclitaxel were included in this retrospective study, as were 42 healthy subjects (47 ± 9 years old)...
October 27, 2016: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/27809613/in-resource-limited-areas-complete-enteral-feed-in-stable-very-low-birth-weight-infants-1000-1500grams-started-within-24%C3%A2-hours-of-life-can-improve-nutritional-outcome
#17
Reeta Bora, Nishchay B Murthy
OBJECTIVE: To evaluate feasibility of complete enteral feed in stable very low birth weight neonates weighing 1000-1500 gms. SUBJECTS AND INTERVENTIONS: One hundred & three stable vlbw neonates (1000-1500gms) irrespective of gestational age were randomized to receive either complete enteral feed(CEF) with expressed breast milk (EBM)(n = 51) or minimal enteral feed (MEF) supplemented with intravenous fluid. (MEF)(n = 52).Feed volume was increased progressively...
November 3, 2016: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27796081/intravoxel-incoherent-motion-ivim-derived-parameters-in-diffusion-weighted-mri-associations-with-prognostic-factors-in-invasive-ductal-carcinoma
#18
Youn Joo Lee, Sung Hun Kim, Bong Joo Kang, Young Jee Kang, Heesoo Yoo, Jaewan Yoo, Jaeun Lee, Yo Han Son, Robert Grimm
PURPOSE: To investigate relationships between intravoxel incoherent motion (IVIM) metrics of invasive ductal carcinoma of the breast and prognostic factors. MATERIALS AND METHODS: This retrospective study included a total of 82 masses from 72 patients who underwent 3T breast magnetic resonance imaging (MRI) and diffusion-weighted imaging. IVIM metrics of tissue diffusivity (Dslow ), pseudodiffusivity (Dfast ), and perfusion fraction (Dpf ) were measured using histogram analysis for whole lesion volumes...
October 31, 2016: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/27788367/novel-method-to-determine-the-lipid-content-of-breast-milk
#19
Shuling Song, Qin Tian, Ling Tong, Meng Pan, Shengming Ma
The fat content of breast milk is important to establish the levels of organic pollutants in human being. Traditional liquid-liquid method was reliability, but time-consuming. In this study, a rapid method that predicts the fat content of breast milk on the basis of an accurate measurement of density is developed. 17 milk powder solutions were prepared, and the densities of these solutions were calculated after measuring its volume and weight. Based on the fat content and density, three equation models, a linear functional equation and two equations obtained by polynomial regression between fat content and density, were established and demonstrated a positive relationship between the fat content and density...
October 24, 2016: Chemosphere
https://www.readbyqxmd.com/read/27788031/quantification-of-radiation-biomarkers-in-leukocytes-of-breast-cancer-patients-treated-with-different-modalities-of-3d-crt-or-imrt
#20
Sebastian Zahnreich, Anne Ebersberger, Heiko Karle, Bernd Kaina, Heinz Schmidberger
The goal of this study was to determine whether the quantification of radiation biomarkers in peripheral leukocytes of 111 breast cancer patients after adjuvant treatment with different modalities of three-dimensional conformal radiation therapy (3D-CRT) or intensity-modulated radiation therapy (IMRT) revealed any difference in the patients' radiation burden by out-of-field doses and an associated risk of second malignancies. Whole-breast radiation therapy was performed by 3D-CRT using either a hard wedge (n = 32) or a virtual wedge (n = 49) at dose rates of 3 and 6 Gy per min each...
October 27, 2016: Radiation Research
keyword
keyword
16496
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"