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Breast volume measurement

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https://www.readbyqxmd.com/read/28437336/both-bilateral-breast-volume-discrepancy-and-asymmetric-anterior-chest-wall-shape-contribute-to-the-unsightly-breast-contour-in-female-right-thoracic-idiopathic-scoliosis
#1
Benlong Shi, Saihu Mao, Xu Sun, Leilei Xu, Feng Zhu, Zezhang Zhu, Bangping Qian, Weijun Wang, Yong Qiu
STUDY DESIGN: A retrospective radiographic study. OBJECTIVE: To evaluate the asymmetry of breast volume (BV) and shape in female adolescent idiopathic scoliosis (AIS) patients and to define their relationship with deformed components of the anterior chest wall and curved spine. SUMMARY OF BACKGROUND DATA: The higher incidence of asymmetric breast development in AIS was described by prior studies. However, the interplay between scoliosis curve magnitude and severity of breast asymmetry (BA) are unknown...
May 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28429195/computer-assisted-diagnosis-system-for-breast-cancer-in-computed-tomography-laser-mammography-ctlm
#2
Afsaneh Jalalian, Syamsiah Mashohor, Rozi Mahmud, Babak Karasfi, M Iqbal Saripan, Abdul Rahman Ramli
Computed tomography laser mammography (Eid et al. Egyp J Radiol Nucl Med, 37(1): p. 633-643, 1) is a non-invasive imaging modality for breast cancer diagnosis, which is time-consuming and challenging for the radiologist to interpret the images. Some issues have increased the missed diagnosis of radiologists in visual manner assessment in CTLM images, such as technical reasons which are related to imaging quality and human error due to the structural complexity in appearance. The purpose of this study is to develop a computer-aided diagnosis framework to enhance the performance of radiologist in the interpretation of CTLM images...
April 20, 2017: Journal of Digital Imaging: the Official Journal of the Society for Computer Applications in Radiology
https://www.readbyqxmd.com/read/28427271/the-value-of-pre-and-post-neoadjuvant-chemotherapy-f-18-fdg-pet-ct-scans-in-breast-cancer-comparison-with-mri
#3
Eun Kyoung Choi, Ie Ryung Yoo, Sung Hun Kim, Sonya Youngju Park, Joo Hyun O, Bong Joo Kang
Background Accurate assessment of neoadjuvant chemotherapy (NAC) response with positron emission tomography/computed tomography (PET/CT) or magnetic resonance imaging (MRI) may provide appropriate operation guidelines for individual breast cancer patients. Purpose To compare the values of PET/CT and MRI for response evaluation following NAC in breast cancer patients. Material and Methods Thirty-three consecutive patients who underwent NAC were included. PET/CT and MRI were performed before and one to four weeks after NAC...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/28421611/breast-density-measurement-using-photon-counting-spectral-mammography
#4
Henrik Johansson, Miriam von Tiedemann, Klaus Erhard, Harald Heese, Huanjun Ding, Sabee Molloi, Erik Fredenberg
PURPOSE: To evaluate a method for measuring breast density using photon-counting spectral mammography. Breast density is an indicator of breast cancer risk and diagnostic accuracy in mammography, and can be used as input to personalized screening, treatment monitoring and dose estimation. METHODS: The measurement method employs the spectral difference in x-ray attenuation between adipose and fibro-glandular tissue, and does not rely on any a-priori information. The method was evaluated using phantom measurements on tissue-equivalent material (slabs and breast-shaped phantoms) and using clinical data from a screening population (n=1329)...
April 19, 2017: Medical Physics
https://www.readbyqxmd.com/read/28420987/curcumin-ameliorates-cisplatin-induced-nephrotoxicity-and-potentiates-its-anticancer-activity-in-sd-rats-potential-role-of-curcumin-in-breast-cancer-chemotherapy
#5
Parveen Kumar, Chandana C Barua, Kunjbihari Sulakhiya, Rajeev Kumar Sharma
Breast malignant neoplastic disease is one of the most complex diseases, as it is a multifactorial disease in which virtually all the targets are instantly or indirectly inter-reliant on each other. Cisplatin (CIS), an inorganic antineoplastic agent is widely utilized in the treatment of various solid tumors including breast cancer. Despite everything, its clinical use is limited, due to ototoxicity, peripheral neuropathy, and nephrotoxicity. The present work was directed to assess the combined result of curcumin (CUR) and CIS in 7, 12-dimethyl benz[a]anthracene (DMBA) induced breast cancer in rats and the prevention of nephrotoxicity induced by the latter...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28420393/medical-treatment-of-mammary-desmoid-type-fibromatosis-which-benefit
#6
Louise Scheer, Massimo Lodi, Sébastien Molière, Jean-Emmanuel Kurtz, Carole Mathelin
BACKGROUND: Breast fibromatosis is a rare disease characterized by monoclonal fibroblast proliferation. It has no ability to metastasize but has a high local recurrence rate and often infiltrates surrounding tissues. Surgical treatment is the reference, but recently, new targeted therapies have emerged. We report an original case of a patient with breast fibromatosis who received exclusive medical treatment. Our aim was to analyze these treatments based on the clinical and radiological outcome, iatrogenic effects, and pharmacological action...
April 18, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28419125/mammographic-compression-in-asian-women
#7
Susie Lau, Yang Faridah Abdul Aziz, Kwan Hoong Ng
OBJECTIVES: To investigate: (1) the variability of mammographic compression parameters amongst Asian women; and (2) the effects of reducing compression force on image quality and mean glandular dose (MGD) in Asian women based on phantom study. METHODS: We retrospectively collected 15818 raw digital mammograms from 3772 Asian women aged 35-80 years who underwent screening or diagnostic mammography between Jan 2012 and Dec 2014 at our center. The mammograms were processed using a volumetric breast density (VBD) measurement software (Volpara) to assess compression force, compression pressure, compressed breast thickness (CBT), breast volume, VBD and MGD against breast contact area...
2017: PloS One
https://www.readbyqxmd.com/read/28415788/inhibitory-effects-of-bmp9-on-breast-cancer-cells-by-regulating-their-interaction-with-pre-adipocytes-adipocytes
#8
Ting Wang, Zhihui Zhang, Ke Wang, Jinshu Wang, Yayun Jiang, Jing Xia, Liyao Gou, Mengyao Liu, Lan Zhou, Tongchuan He, Yan Zhang
Bone morphogenetic protein 9 (BMP9) possesses multiple functions, but its effects on breast cancer cells in adipose microenvironment are still unclear. This study aimed to investigate whether BMP9 is able to modulate the interaction between pre-adipocytes/adipocytes and breast cancer cells. An in vitro co-culture system was established by using pre-adipocytes/adipocytes and MDA-MB-231 breast cancer cells with BMP9 over-expression. The leptin expression and leptin-induced signaling pathway were evaluated in this co-culture system...
March 16, 2017: Oncotarget
https://www.readbyqxmd.com/read/28410763/correlation-between-upper-limb-volume-and-arterial-and-venous-blood-flow-velocity-in-lymphedema-secondary-to-breast-cancer-treatment
#9
Monique Silva Rezende, Ana Luiza Marsengo, Amanda Apolinário, Vânia Tie Koga Ferreira, Elaine Caldeira de Oliveira Guirro
OBJECTIVE: The purpose of this study was to correlate upper limb volume and arterial and venous blood flow velocity in breast cancer survivors. METHODS: A cross-sectional study was conducted on 30 women with lymphedema and a mean age of 55.60 years (standard deviation = 8.12). For the assessment of upper limb volume, perimetry was performed with measures at 6 points on the limb, which were mathematically calculated as volume. The blood flow velocity of the axillary and brachial arteries and veins were assessed by Doppler ultrasound with a probe at 4 MHz...
April 12, 2017: Journal of Manipulative and Physiological Therapeutics
https://www.readbyqxmd.com/read/28408284/conversion-from-weight-to-volume-of-mastectomy-specimen-convenient-equations
#10
Jun Ho Lee, Chi-Ho Yeo, Taegon Kim, Kyu-Jin Chung, Soo Jung Lee, Su Hwan Kang, Jung Eun Choi
Accurate restoration of the volume lost during breast removal is the key to achieve beautiful, symmetric breasts. This study aimed to devise a simpler and more accurate method for measuring breast tissue volume by studying the relationship between weight and volume of the excised tissue according to density. Mammograms of 276 women who were advised to undergo breast reconstruction surgery were divided into 4 different groups according to tissue densities. The correlation between weight and volume was studied for each group...
February 27, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/28398210/out-of-field-doses-from-pediatric-craniospinal-irradiations-using-3d-crt-imrt-helical-tomotherapy-and-electron-based-therapy
#11
Marijke De Saint-Hubert, Dirk Verellen, Kenneth Poels, Wouter Crijns, Federica Magliona, Tom Depuydt, Filip Vanhavere, Lara Struelens
Medulloblastoma treatment involves irradiation of the entire central nervous system, i.e craniospinal irradiation (CSI). This is associated with significant exposure of large volumes of healthy tissue with a growing concern regarding treatment associated side effects. The current study compares out-of-field organ doses in children receiving CSI with three-dimensional-conformal radiotherapy (3D-CRT), intensity modulated radiotherapy (IMRT), helical tomotherapy (HT) and an electron-based technique, including as well radiation doses resulting from imaging performed during treatment...
April 11, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28395671/longitudinal-assessment-of-right-ventricular-structure-and-function-by-cardiovascular-magnetic-resonance-in-breast-cancer-patients-treated-with-trastuzumab-a-prospective-observational-study
#12
Ashita Barthur, Christine Brezden-Masley, Kim A Connelly, Vinita Dhir, Kelvin K W Chan, Rashida Haq, Anish Kirpalani, Joseph J Barfett, Laura Jimenez-Juan, Gauri R Karur, Djeven P Deva, Andrew T Yan
BACKGROUND: There are limited data on the effects of trastuzumab on the right ventricle (RV). Therefore, we sought to evaluate the temporal changes in right ventricular (RV) structure and function as measured by cardiovascular magnetic resonance (CMR), and their relationship with left ventricular (LV) structure and function in breast cancer patients treated with trastuzumab. METHODS: Prospective, longitudinal, observational study involving 41 women with HER2+ breast cancer who underwent serial CMR at baseline, 6, 12, and 18 months after initiation of trastuzumab...
April 10, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28381475/dairy-intake-in-relation-to-breast-and-pubertal-development-in-chilean-girls
#13
Audrey J Gaskins, Ana Pereira, Daiana Quintiliano, John A Shepherd, Ricardo Uauy, Camila Corvalán, Karin B Michels
Background: Frequent dairy consumption in childhood has been related to higher growth-hormone concentrations that may affect mammary gland and pubertal development.Objective: We evaluated the relation of dairy intake to breast composition at Tanner stage 4 and age at menarche.Design: A total of 515 Chilean girls are included in the Growth and Obesity Cohort Study. The subjects have been followed longitudinally since they were 3-4 y old (from 2006 to the present). Starting in 2013, diet was assessed every 6 mo via a 24-h recall...
April 5, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28379383/2d-and-3d-strain-for-detection-of-subclinical-anthracycline-cardiotoxicity-in-breast-cancer-patients-a-balance-with-feasibility
#14
Ciro Santoro, Grazia Arpino, Roberta Esposito, Maria Lembo, Immacolata Paciolla, Cinzia Cardalesi, Giovanni de Simone, Bruno Trimarco, Sabino De Placido, Maurizio Galderisi
Aims: 2D echocardiography is limited for identifying chemotherapy-related cardiotoxicity. This study compared standard echo, 2D, and 3D speckle tracking echocardiography (STE) for detection of subclinical anthracycline (ANT) cardiotoxicity in breast cancer patients. Methods and results: One-hundred consecutive breast cancer patients free of cardiac symptoms were treated by multiple protocols including ANT and cyclophosphamide and/or 5-fluorouracil for 3-4 cycles...
March 31, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28375584/fully-automated-segmentation-of-whole-breast-using-dynamic-programming-in-dynamic-contrast-enhanced-mr-images
#15
Luan Jiang, Xiaoxin Hu, Qin Xiao, Yajia Gu, Qiang Li
PURPOSE: Amount of fibroglandular tissue (FGT) and level of background parenchymal enhancement (BPE) in breast dynamic contrast enhanced magnetic resonance images (DCE-MRI) are suggested as strong indices for assessing breast cancer risk. Whole breast segmentation is the first important task for quantitative analysis of FGT and BPE in three-dimensional (3-D) DCE-MRI. The purpose of this study is to develop and evaluate a fully automated technique for accurate segmentation of the whole breast in 3-D fat-suppressed DCE-MRI...
April 4, 2017: Medical Physics
https://www.readbyqxmd.com/read/28374885/variations-in-the-sonographic-measurement-techniques-of-bi-rads-3-breast-masses
#16
Juliana Francisco, Rodrigo Menezes Jales, André Desuó Bueno de Oliveira, Carlos Henrique Francisco Arguello, Sophie Derchain
OBJECTIVE: To evaluate the differences in sonographic (US) distance and volume measurements from different sonologists and identify the optimal parameters to avoid clinically relevant variations in the measurement of BI-RADS 3 breast masses. METHODS: For this cross-sectional study with prospectively collected data, four physicians with various levels of experience in US, herein called sonologists, performed distance and volume US measurements of 80 masses classified as BI-RADS 3...
April 4, 2017: Journal of Clinical Ultrasound: JCU
https://www.readbyqxmd.com/read/28371110/computer-aided-heterogeneity-analysis-in-breast-mr-imaging-assessment-of-ductal-carcinoma-in-situ-correlating-histologic-grade-and-receptor-status
#17
Shinn-Huey S Chou, Eva C Gombos, Sona A Chikarmane, Catherine S Giess, Jagadeesan Jayender
PURPOSE: To identify breast MR imaging biomarkers to predict histologic grade and receptor status of ductal carcinoma in situ (DCIS). MATERIALS AND METHODS: Informed consent was waived in this Health Insurance Portability and Accountability Act-compliant Institutional Review Board-approved study. Case inclusion was conducted from 7332 consecutive breast MR studies from January 1, 2009, to December 31, 2012. Excluding studies with benign diagnoses, studies without visible abnormal enhancement, and pathology containing invasive disease yielded 55 MR-imaged pathology-proven DCIS seen on 54 studies...
April 3, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28370289/estimating-breast-tumor-blood-flow-during-neoadjuvant-chemotherapy-using-interleaved-high-temporal-and-high-spatial-resolution-mri
#18
Leonidas Georgiou, Nisha Sharma, David A Broadbent, Daniel J Wilson, Barbara J Dall, Anmol Gangi, David L Buckley
PURPOSE: To evaluate an interleaved MRI sampling strategy that acquires both high temporal resolution (HTR) dynamic contrast-enhanced (DCE) data for quantifying breast tumor blood flow (TBF) and high spatial resolution (HSR) DCE data for clinical reporting, following a single standard injection of contrast agent. METHODS: A simulation study was used to evaluate the performance of the interleaved technique under different conditions. In a prospective clinical study, 18 patients with primary breast cancer, who were due to undergo neoadjuvant chemotherapy (NACT), were examined using interleaved HTR and HSR DCE-MRI at 1...
April 3, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28369094/clinical-application-of-a-microfluidic-chip-for-immunocapture-and-quantification-of-circulating-exosomes-to-assist-breast-cancer-diagnosis-and-molecular-classification
#19
Shimeng Fang, Hongzhu Tian, Xiancheng Li, Dong Jin, Xiaojie Li, Jing Kong, Chun Yang, Xuesong Yang, Yao Lu, Yong Luo, Bingcheng Lin, Weidong Niu, Tingjiao Liu
Increasing attention has been attracted by exosomes in blood-based diagnosis because cancer cells release more exosomes in serum than normal cells and these exosomes overexpress a certain number of cancer-related biomarkers. However, capture and biomarker analysis of exosomes for clinical application are technically challenging. In this study, we developed a microfluidic chip for immunocapture and quantification of circulating exosomes from small sample volume and applied this device in clinical study. Circulating EpCAM-positive exosomes were measured in 6 cases breast cancer patients and 3 healthy controls to assist diagnosis...
2017: PloS One
https://www.readbyqxmd.com/read/28363661/breast-fat-volume-measurement-using-wide-bore-3%C3%A2-t-mri-comparison-of-traditional-mammographic-density-evaluation-with-mri-density-measurements-using-automatic-segmentation
#20
E Petridou, M Kibiro, C Gladwell, P Malcolm, A Toms, A Juette, M Borga, O Dahlqvist Leinhard, T Romu, B Kasmai, E Denton
AIM: To compare magnetic resonance imaging (MRI)-derived breast density measurements using automatic segmentation algorithms with radiologist estimations using the Breast Imaging Reporting and Data Systems (BI-RADS) density classification. MATERIALS AND METHODS: Forty women undergoing mammography and dynamic breast MRI as part of their clinical management were recruited. Fat-water separated MRI images derived from a two-point Dixon technique, phase-sensitive reconstruction, and atlas-based segmentation were obtained before and after intravenous contrast medium administration...
March 28, 2017: Clinical Radiology
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