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Carbapenemasas

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https://www.readbyqxmd.com/read/29165508/-test-evaluation-and-strategy-proposal-to-detect-and-to-characterize-carbapenemase-producing-gram-negative-bacilli
#1
Constanza Muñoz, Cecilia Zumarán, Tamara González, Aniela Wozniak, Claudia Castillo, Patricia García
INTRODUCTION: The detection of carbapenemase-producing gram negative bacilli is complicated, because there are available multiple options of test. The confirmation of the enzyme by molecular characterization is not available in all laboratories in our country. OBJECTIVE: To propose a fast, efficient and simple strategy to detect and confirm CPB. MATERIALS AND METHODS: 39 CPB isolates and 8 non-producing were used to evaluate the phenotypic test Carba NP, CarbAcineto NP and Blue-Carba, validating the test Xpert® Carba-R, to be used directly with bacterial colonies with conventional PCR...
August 2017: Revista Chilena de Infectología: órgano Oficial de la Sociedad Chilena de Infectología
https://www.readbyqxmd.com/read/25679924/-detection-of-serinocarbapenemases-class-a-and-other-mechanisms-of-enzymatic-resistance-to-%C3%AE-lactams-in-enterobacteria-strains-with-diminished-susceptibility-to-carbapenems-isolated-of-patients-in-a-university-hospital
#2
Virginia de la Lastra, Lina M Rivas, Francisco Silva, M Teresa Ulloa, M Eugenia Pinto, Mario Vidal
BACKGROUND: The emergence of carbapenemase mediated resistance in Enterobacteriaceae has a strong clinical impact. This study aimed to do a genotypic and phenotypic characterization of the enzymatic resistance to β-lactams in clinical Enterobacteriaceae isolates with decreased susceptibility to carbapenems in a university medical center in Santiago. METHODS: During April-September 2010 at Hospital Clinico Universidad de Chile, 23 isolates of carbapenem non susceptible Enterobacteriaceae were collected...
December 2014: Revista Chilena de Infectología: órgano Oficial de la Sociedad Chilena de Infectología
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