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https://www.readbyqxmd.com/read/30336220/risk-factors-clinical-course-and-outcomes-of-pregnancy-related-group-a-streptococcal-infections-a-retrospective-13-year-cohort-study
#1
Amihai Rottenstreich, Shmuel Benenson, Gabriel Levin, Geffen Kleinstern, Allon E Moses, Sharon Amit
OBJECTIVES: To investigate the incidence, risk factors, clinical course and outcomes of pregnancy-related group A streptococcus (GAS) infection. METHODS: A retrospective 13-year cohort study of culture-proven pregnancy-related GAS infection was performed at two university hospitals, serving heterogeneous, multicultural, urban and rural populations. RESULTS: Of 124 women diagnosed with pregnancy-related GAS infection, 115 (93%) were in the puerperium, an incidence of 0...
October 15, 2018: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/30327863/sonographic-prediction-of-macrosomia-in-pregnancies-complicated-by-maternal-diabetes-finding-the-best-formula
#2
Anat Shmueli, Lina Salman, Eran Hadar, Amir Aviram, Ron Bardin, Eran Ashwal, Rinat Gabbay-Benziv
PURPOSE: To evaluate the best performing formula for macrosomia prediction in pregnancies complicated by diabetes. METHODS: A retrospective analysis was performed of 1060 sonographic fetal biometrical measurements performed within 7 days of delivery in term pregnancies (37-42 gestational weeks) complicated by diabetes. Sonographic prediction of macrosomia (≥ 4000, ≥ 4250, and ≥ 4500 g) was evaluated utilizing ten previously published formulas by: (1) calculating for each macrosomia threshold the sensitivity, specificity, positive and negative predictive value, and ± likelihood ratio for macrosomia prediction; (2) comparing the systematic and random error and the proportion of estimates < 10% of birth weights between macrosomic and non-macrosomic neonates...
October 16, 2018: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/30325605/removal-of-intramural-trapped-intrauterine-device-by-cystoscopic-incision-of-bladder-wall
#3
Abbas Basiri, Behnam Shakiba, Niloufar Rostaminejad
A healthy 37 - year - old woman referred to our clinic with one - year history of recurrent urinary tract infection, dysuria and frequency. Her past medical history informed us that an IUD (Copper TCu380A) had been inserted 11 years ago. Eleven months after the IUD insertion she had become pregnant, unexpectedly. At that time, she had undergone gynecological examination and abdominal ultrasound study. However, the IUD had not been found, and the gynecologist had made the diagnosis of spontaneous fall out of the IUD...
September 20, 2018: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/30322724/early-clindamycin-for-bacterial-vaginosis-in-pregnancy-premeva-a-multicentre-double-blind-randomised-controlled-trial
#4
Damien Subtil, Gilles Brabant, Emma Tilloy, Patrick Devos, Frédérique Canis, Annie Fruchart, Marie-Christine Bissinger, Jean-Charles Dugimont, Catherine Nolf, Christophe Hacot, Sophie Gautier, Jérôme Chantrel, Marielle Jousse, David Desseauve, Jean Louis Plennevaux, Christine Delaeter, Sylvie Deghilage, Anne Personne, Emmanuelle Joyez, Elisabeth Guinard, Eric Kipnis, Karine Faure, Bruno Grandbastien, Pierre-Yves Ancel, François Goffinet, Rodrigue Dessein
BACKGROUND: Preterm delivery during pregnancy (<37 weeks' gestation) is a leading cause of perinatal mortality and morbidity. Treating bacterial vaginosis during pregnancy can reduce poor outcomes, such as preterm birth. We aimed to investigate whether treatment of bacterial vaginosis decreases late miscarriages or spontaneous very preterm birth. METHODS: PREMEVA was a double-blind randomised controlled trial done in 40 French centres. Women aged 18 years or older with bacterial vaginosis and low-risk pregnancy were eligible for inclusion and were randomly assigned (2:1) to three parallel groups: single-course or triple-course 300 mg clindamycin twice-daily for 4 days, or placebo...
October 12, 2018: Lancet
https://www.readbyqxmd.com/read/30318100/effects-of-trimester-specific-exposure-to-vanadium-on-ultrasound-measures-of-fetal-growth-and-birth-size-a-longitudinal-prospective-prenatal-cohort-study
#5
Jie Hu, Yang Peng, Tongzhang Zheng, Bin Zhang, Wenyu Liu, Chuansha Wu, Minmin Jiang, Joseph M Braun, Simin Liu, Stephen L Buka, Aifen Zhou, John Pierce Wise, Yiming Zhang, Yangqian Jiang, Chen Hu, Xiaomei Chen, Zheng Huang, Dan Zheng, Kunchong Shi, Xichi Zhang, Ashley Truong, Zhengmin Qian, Wei Xia, Yuanyuan Li, Shunqing Xu
BACKGROUND: Identification of windows of heightened vulnerability to environmental factors has substantial public health implications. Prenatal exposure to vanadium has been linked to adverse birth outcomes; however, critical windows for such exposure during fetal growth remain unknown. We aimed to assess trimester-specific associations of vanadium exposure with ultrasound measures of fetal growth and birth size in a Chinese longitudinal cohort. METHODS: The present study was embedded in our ongoing prospective prenatal cohort study at the Wuhan Women and Children Medical Care Center (Wuhan, Hubei, China)...
October 2018: Lancet. Planetary Health
https://www.readbyqxmd.com/read/30317274/severe-haemolysis-and-renal-failure-precipitated-by-hepatitis-e-virus-in-g6pd-deficient-patient-a-case-report
#6
Baseer Sultan Ahmad, Adeel Ahmad, Sajjad Jamil, Saiyed Abdullah Abubakar Mohsin Ehsanullah, Abeera Munir
Hepatitis E virus is the etiological agent for Hepatitis E infection, which is congruent to Hepatitis A infection. The clinical spectrum of the disease range from asymptomatic self-limiting disease which requires no treatment to life threatening fulminant liver disease in pregnancy, G6PD deficient and post-liver transplant patients, which necessitate urgent treatment. Similarly we are reporting a case of a 28 year old male with no previous known comorbids, who presented in emergency department with low grade fever, yellow discolouration of eyes and upper abdominal pain for last 5-6 days...
September 2018: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/30316713/prediction-of-sga-at-birth-by-using-the-right-portal-vein-diameter-measurement-at-the-30-35-week-scan
#7
Iglika Ivancheva Simeonova-Brachot
OBJECTIVE: This study sought to test the hypothesis that the measurement of the right portal vein (RPV) diameter on the transverse abdominal view at the 32-week ultrasound scan is small in fetuses with growth retardation and to validate the use of this measurement as a tool for detecting SGA at birth. METHODS: This was a retrospective cohort study at a single centre. The study population comprised 326 consecutive pregnancies, including 29 SGA at delivery and 297 unaffected cases...
October 10, 2018: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/30316439/primary-hepatic-pregnancy-report-of-a-case-treated-with-laparoscopic-approach-and-review-of-the-literature
#8
Simone Garzon, Ricciarda Raffaelli, Umberto Montin, Fabio Ghezzi
OBJECTIVE: To report a case of primary hepatic pregnancy complicated by acute hemoperitoneum that was treated with a laparoscopic approach. DESIGN: Case report and review of the literature. SETTING: Obstetrics and gynecology unit of a university hospital. PATIENT(S): A 37-year-old pregnant woman who presented with vaginal bleeding. INTERVENTION(S): Diagnosis by abdominal ultrasound and computed tomography...
October 2018: Fertility and Sterility
https://www.readbyqxmd.com/read/30306037/successful-procedure-in-conservative-management-of-interstitial-cornual-ectopic-pregnancy
#9
Cepi Teguh Pramayadi, Alvin Bramantyo, Eka Rusdianto Gunardi
A 35-year-old woman presented with spotting and lower abdominal pain. Follow-up sonography was suggestive of interstitial ectopic pregnancy. Laparoscopic cornuostomy was carried out. Before incision, diluted vasopressin was injected around the site of interstitial pregnancy. Removal of the conceptual tissues was conducted smoothly through a 1.5 cm incision. The overall blood loss was 50 mL. The operative time was 50 min, and there were no intraoperative complications. We successfully performed laparoscopic cornuostomy, which was followed by an unremarkable postoperative course...
October 2018: Gynecology and minimally invasive therapy
https://www.readbyqxmd.com/read/30294183/evaluation-of-cardiovascular-risk-in-climacteric-women-a-cross-sectional-study
#10
Martha Pantel Dos Santos Mota, Isabel Cristina Gomes Moura, Ricardo Mello Marinho, Eduardo Back Sternick, Alessandra Maciel Almeida
Purpose: To identify cardiovascular risk factors in women between 40 and 65 years old in two private clinic of gynecology in Minas Gerais. Methods: Cross-sectional study from January/2016 to January/2017 in 137 climacteric women. A standardized questionnaire was used to evaluate socio-demographic characteristics, climacteric phases, cardiovascular risk factors, menopause (age, time and type), number of pregnancies, normal births, abortions, partners and hormonal therapy...
July 2018: Journal of Mid-life Health
https://www.readbyqxmd.com/read/30293990/molecular-autopsy-by-trio-exome-sequencing-es-and-postmortem-examination-in-fetuses-and-neonates-with-prenatally-identified-structural-anomalies
#11
Elizabeth Quinlan-Jones, Jenny Lord, Denise Williams, Sue Hamilton, Tamas Marton, Ruth Y Eberhardt, Gabriele Rinck, Elena Prigmore, Rebecca Keelagher, Dominic J McMullan, Eamonn R Maher, Matthew E Hurles, Mark D Kilby
PURPOSE: To determine the diagnostic yield of combined exome sequencing (ES) and autopsy in fetuses/neonates with prenatally identified structural anomalies resulting in termination of pregnancy, intrauterine, neonatal, or early infant death. METHODS: ES was undertaken in 27 proband/parent trios following full autopsy. Candidate pathogenic variants were classified by a multidisciplinary clinical review panel using American College of Medical Genetics and Genomics (ACMG) guidelines...
October 8, 2018: Genetics in Medicine: Official Journal of the American College of Medical Genetics
https://www.readbyqxmd.com/read/30293400/postpartum-stretchmarks-repairing-activity-of-an-oral-centella-asiatica-supplementation-centellicum%C3%A2
#12
Shu Hu, Gianni Belcaro, Morio Hosoi, Beatrice Feragalli, Roberta Luzzi, Mark Dugall
BACKGROUND: This registry study evaluates the effects of oral Centellicum®, a new preparation of Centella asiatica (CA) on cutaneous stretchmarks (SMs) on the lower abdominal wall in comparison with the topical treatment with a specific antistretch cream. This cream is used for pregnancy SMs. The aim of the management was to give back to the structurally damaged skin areas (apparent as SMs) a normal elasticity and resistance and improving the local microcirculation. METHODS: We selected 78 healthy women with SMs at least 6 months postpartum available to follow the registry plan...
October 2018: Minerva Ginecologica
https://www.readbyqxmd.com/read/30290187/updated-review-of-current-pharmacological-and-non-pharmacological-management-of-irritable-bowel-syndrome
#13
Prashanth Rawla, Tagore Sunkara, Jeffrey Pradeep Raj
Irritable bowel syndrome (IBS) is a functional disorder of the gastrointestinal tract that is usually associated with chronic abdominal pain and altered bowel habits. The two spectra of the disease include constipation-predominant IBS and Diarrhea-predominant IBS. Earlier it was thought to be an unexplained brain-gut disorder, but of late, various underlying causes suggesting primary gut disturbance have been identified. The initial management primarily includes the non-pharmacological measures such as dietary modifications, increasing physical activity, and psychological therapy...
October 2, 2018: Life Sciences
https://www.readbyqxmd.com/read/30288859/herniation-of-the-amniotic-sac-through-congenital-uterine-defect-confirmed-during-operation-a-case-report
#14
Xiwen Sun, Jingwei Xu, Yuanyuan Liu, Xinyuan Teng, Liquan Wang
Herniation of the amniotic sac into the peritoneal cavity or bladder is a rare but serious condition during pregnancy, which has not been reported in pored congenital uterine anomaly. Here, we report a rare case to draw obstetricians' attention to the atypical uterine rupture. A primigravida at 35 weeks of gestation was admitted for upper abdominal pain. A primary diagnosis of uterine rupture was made after finding the amniotic sac herniation through obstetric ultrasound. Exploration during emergent cesarean section revealed symmetrical pored defect on the uterine horn...
October 4, 2018: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/30288740/an-unusual-presentation-of-rectal-carcinoma-with-group-g-streptococcal-sepsis-in-the-early-third-trimester
#15
Rhiannon Evans, Sylvia Lin
No abstract text is available yet for this article.
October 4, 2018: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/30288170/successful-pregnancy-outcome-in-recurrent-ovarian-cancer-in-a-26-year-old-a-case-report
#16
Savita Rani Singhal, Susheela Chaudhary, Kriti Agarwal, Anjali Gupta
Objective: To report a case of Successful Pregnancy Outcome in Recurrent Ovarian Cancer in a 26 year Old. Case Report: A 26 years old primigravida presented in antenatal clinic at 23 weeks of pregnancy with recurrence of ovarian cancer of mucinous type. Following refusal of surgical management, two courses of single dose carboplatin was administered. However, before third cycle of chemotherapy could be administered ,there was deranged liver functions tests, following which elective Cesarean section with staging laparotomy was planned at 34 weeks for breech presentation with oligohydramnios...
December 2017: Journal of Family & Reproductive Health
https://www.readbyqxmd.com/read/30285230/female-adiposity-and-time-to-pregnancy-a-multiethnic-prospective-cohort
#17
S L Loy, Y B Cheung, S E Soh, S Ng, M T Tint, I M Aris, J Y Bernard, Y S Chong, K M Godfrey, L P Shek, K H Tan, Y S Lee, H H Tan, B S M Chern, N Lek, F Yap, S Y Chan, C Chi, J K Y Chan
STUDY QUESTION: Are higher overall and central adiposity associated with reduced fecundability, measured by time-to-pregnancy (TTP), in Asian women? SUMMARY ANSWER: Higher overall adiposity, but not central adiposity, was associated with longer TTP in Asian women. WHAT IS KNOWN ALREADY: High body mass index (BMI) has been associated with a longer TTP, although the associations of body composition and distribution with TTP are less clear. There are no previous studies of TTP in Asian women, who have a relatively higher percentage of body fat and abdominal fat at relatively lower BMI...
October 4, 2018: Human Reproduction
https://www.readbyqxmd.com/read/30280305/treatment-of-hereditary-angioedema-attacks-with-icatibant-and-recombinant-c1-inhibitor-during-pregnancy
#18
Roman Hakl, Pavel Kuklínek, Irena Krčmová, Pavlína Králíčková, Tomáš Freiberger, Petr Janků, Marcela Vlková, Jiří Litzman
PURPOSE: Hereditary angioedema (HAE) is a rare disease caused by a C1 inhibitor (C1-INH) deficit. Clinically, HAE is manifested by repeated episodes of localized subcutaneous or submucosal oedema attacks. Managing HAE patients in pregnancy is challenging, since there are only limited data on the safety and efficacy of various therapeutic approaches. METHODS: We present our clinical experience treating acute HAE attacks during pregnancy in six consecutive patients...
October 2018: Journal of Clinical Immunology
https://www.readbyqxmd.com/read/30279994/diagnosis-and-management-of-a-heterotopic-pregnancy-and-ruptured-rudimentary-uterine-horn
#19
Paula C Brady, Rose L Molina, Michael G Muto, Brenna Stapp, Serene S Srouji
Background: Heterotopic pregnancies implanted in a rudimentary uterine horn account for 1 in 2-3 million gestations, and confer significant risk of morbidity due to uterine rupture and hemorrhage. Case presentation: A 34-year-old nullipara presented with acute pelvic pain at 17 weeks of gestation with dichorionic-diamniotic twins, one in each horn of an anomalous uterus first diagnosed in pregnancy as bicornuate. Three-dimensional ultrasound and MRI revealed myometrial disruption in the left rudimentary uterine horn, and the patient underwent an uncomplicated abdominal hemi-hysterectomy...
2018: Fertility Research and Practice
https://www.readbyqxmd.com/read/30264855/association-of-spontaneous-labor-onset-with-neonatal-outcomes-in-pregnancies-with-fetal-gastroschisis-a-retrospective-cohort-analysis
#20
Gilmar de Souza Osmundo Junior, Samirah Hosney Mahmoud Mohamed, Estela Naomi Nishie, Ana Cristina Aoun Tannuri, Maria Augusta Bento Cicaroni Gibelli, Rossana Pulcineli Vieira Francisco, Maria de Lourdes Brizot
INTRODUCTION: The present study aims to investigate the association of spontaneous labor onset with neonatal outcomes in pregnancies with fetal gastroschisis. The secondary goal was to evaluate the association between ultrasound markers and labor onset in pregnancies with fetal gastroschisis. MATERIAL AND METHODS: A retrospective analysis was performed for 207 pregnancies with fetal gastroschisis followed between 2005 and 2017. Patients were followed according to a strict protocol involving ultrasound scans and routine evaluations of fetal biophysical profile parameters and intra- and extra-abdominal bowel diameters...
September 28, 2018: Acta Obstetricia et Gynecologica Scandinavica
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