keyword
MENU ▼
Read by QxMD icon Read
search

AKIN criteria

keyword
https://www.readbyqxmd.com/read/30111187/discoveries-on-the-genetics-of-adhd-in-the-21st-century-new-findings-and-their-implications
#1
Anita Thapar
The 21st century has witnessed the discovery of multiple rare and common gene variants associated with attention deficit hyperactivity disorder (ADHD), and these discoveries have already provided a starting point for the investigation of the biology of the disorder and novel treatments. The purpose of this selective review is to examine genetic findings from the past 5 years and consider their implications for the conceptualization of ADHD and future clinical practice. Recent discoveries reveal the strong genetic overlaps between ADHD and autism spectrum disorder (ASD) as well as intellectual disability...
August 16, 2018: American Journal of Psychiatry
https://www.readbyqxmd.com/read/30078412/clinical-implications-of-clonal-hematopoiesis
#2
REVIEW
David P Steensma
Clonal hematopoiesis (CH)-an expansion of blood cells derived from a single hematopoietic stem cell-is a defining feature of hematologic cancers, but recently CH was also found to be a frequent consequence of aging. When aging-associated CH results from acquisition of a somatic mutation in a driver gene associated with leukemia, and this mutation is present at a variant allele frequency of at least 0.02 (2%) yet the patient does not meet World Health Organization diagnostic criteria for a hematologic neoplasm, this state is termed clonal hematopoiesis of indeterminate potential (CHIP)...
August 2018: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/30075798/a-worldwide-multicentre-evaluation-of-the-influence-of-deterioration-or-improvement-of-acute-kidney-injury-on-clinical-outcome-in-critically-ill-patients-with-and-without-sepsis-at-icu-admission-results-from-the-intensive-care-over-nations-audit
#3
Esther Peters, Massimo Antonelli, Xavier Wittebole, Rahul Nanchal, Bruno François, Yasser Sakr, Jean-Louis Vincent, Peter Pickkers
BACKGROUND: Acute kidney injury (AKI) is a common complication of critical illness and is associated with worse outcomes. However, the influence of deterioration or improvement in renal function on clinical outcomes is unclear. Using a large international database, we evaluated the prevalence and evolution of AKI over a 7-day period and its effects on clinical outcomes in septic and non-septic critically ill patients worldwide. METHODS: From the 10,069 adult intensive care unit (ICU) patients in the Intensive Care Over Nations database, all those with creatinine and urine output data were included in this substudy...
August 3, 2018: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/30051166/drd3-gene-and-adhd-a-pharmaco-behavioural-genetic-study
#4
Weam Fageera, Sarojini M Sengupta, Aurelie Labbe, Natalie Grizenko, Ridha Joober
Results of candidate gene investigations in ADHD have been difficult to replicate. The complexity of the phenotypes and their underlying determinants, and the relatively small effect sizes of genetic variants may, in part, be contributing to these inconsistencies. The objective of this study is to conduct an exploratory analysis using a comprehensive approach to investigate the role of candidate genes. This approach combines a dimensional behavioural approach akin to Research Domain Criteria (RDoC), a pharmaco-dynamic evaluation of behaviours relevant to ADHD, together with association and linkage testing in a large sample of children with ADHD...
July 26, 2018: Neuromolecular Medicine
https://www.readbyqxmd.com/read/30025391/method-used-for-tumor-bed-closure-suture-vs-sealant-ischemia-time-and-duration-of-surgery-are-independent-predictors-of-post-nephron-sparing-surgery-acute-kidney-injury
#5
Omri Nativ, Zaher Bahouth, Edmond Sabo, Sarel Halachmi, Boaz Moskovitz, Elias G Hellou, Zaid Abassi, Ofer Nativ
INTRODUCTION: The aim of our study was to examine the influence of tumor complexity and operative variables on the degree and rate of post-nephron sparing surgery (NSS) acute kidney injury (AKI). METHODS: We retrospectively reviewed the records of 477 patients who underwent NSS for enhancing renal masses in our institution. AKI was determined using the latest definition by AKIN and RIFLE criteria. Serum creatinine was assessed daily starting from day 1 post-surgery and until discharge (usually on postoperative day 3)...
July 19, 2018: Urologia Internationalis
https://www.readbyqxmd.com/read/29984336/can-tumor-recurrence-be-reduced-with-plasma-kinetic-vaporization-of-the-area-around-the-tumor-in-nonmuscle-invasive-bladder-cancer
#6
Yüksel Yılmaz, Mehmet Cemal Kahya, Fatma Hüsniye Dilek, Osman Köse, Serkan Özcan, Ertan Can, Yiğit Akın, Batuhan Ergani, Ahmet Selçuk Dindar
Purpose: To investigate the effect on recurrence of vaporization of the tumor surroundings and suspicious areas with a plasma-kinetic (PK) system after transurethral resection (TUR) of nonmuscle invasive bladder cancer. Materials and Methods: The study included 121 patients with a primary superficial bladder tumor who were randomized as those who underwent TUR with the PK system (Group 1, n=62) and those who underwent TUR with the monopolar system (Group 2, n=59)...
July 2018: Investigative and Clinical Urology
https://www.readbyqxmd.com/read/29980878/prediction-of-chronic-kidney-disease-after-acute-kidney-injury-in-icu-patients-study-protocol-for-the-predict-multicenter-prospective-observational-study
#7
Guillaume Geri, Bénédicte Stengel, Christian Jacquelinet, Philippe Aegerter, Ziad A Massy, Antoine Vieillard-Baron
BACKGROUND: Acute kidney injury (AKI) is frequent and associated with poor outcome in intensive care unit (ICU) patients. Besides the association with short- and long-term mortality, the increased risk of chronic kidney disease (CKD) has been recently highlighted in non-ICU patients. This study aims to describe the incidence and determinants of CKD after AKI and to develop a prediction score for CKD in ICU patients. METHODS: Prospective multicenter (n = 17) observational study included 1200 ICU patients who suffered from AKI (defined by an AKIN stage ≥ 1) during their ICU stay and were discharged alive from ICU...
July 6, 2018: Annals of Intensive Care
https://www.readbyqxmd.com/read/29970747/pediatric-acute-kidney-injury-in-north-india-a-prospective-hospital-based-study
#8
Shariq Nawaz, Kamran Afzal
The conducted study aimed to determine the incidence and clinical profile of acute kidney injury (AKI) in hospitalized patients using the AKI Network (AKIN) criteria. This prospective observational study was conducted at the Pediatric ward and pediatric Intensive Care Unit of a tertiary level teaching hospital in North India. The participants were 763 consecutive patients aged three months to 12 years from January 2014 to October 2015 and were assessed for eligibility. Of these, 163 patients were excluded from the study...
May 2018: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/29945330/pentraxin-3-predicts-short-and-mid-term-mortality-in-patients-with-sepsis-and-septic-shock-during-intensive-care-treatment
#9
Sonja Hamed, Michael Behnes, Dominic Pauly, Dominic Lepiorz, Max Barre, Tobias Becher, Siegfried Lang, Ibrahim Akin, Martin Borggrefe, Thomas Bertsch, Ursula Hoffmann
BACKGROUND: The prognostic value of the acute phase protein Pentraxin 3 (PTX-3) is not well evaluated in patients with septic shock, which reveal an unacceptably high short- and long-term mortality. New Sepsis-3 definitions are not yet implemented in most biomarker studies. Therefore, this study assesses the prognostic value of PTX-3 for short- and mid-term mortality in patients with sepsis or septic shock, as defined by the latest definitions, treated at a medical intensive care unit (ICU)...
June 1, 2018: Clinical Laboratory
https://www.readbyqxmd.com/read/29928922/mast-cell-activation-syndrome-importance-of-consensus-criteria-and-call-for-research
#10
Peter Valent, Cem Akin, Patrizia Bonadonna, Karin Hartmann, Sigurd Broesby-Olsen, Knut Brockow, Joseph H Butterfield, Andreas Reiter, Jason Gotlib, Mariana Castells, Joshua D Milner, Melody C Carter, Hirsh Komarow, Deepti Radia, Animesh Pardanani, Karl Sotlar, Massimo Triggiani, Hans-Peter Horny, Michel Arock, Lawrence B Schwartz, Dean D Metcalfe
No abstract text is available yet for this article.
June 19, 2018: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29910040/sodium-bicarbonate-therapy-for-patients-with-severe-metabolic-acidaemia-in-the-intensive-care-unit-bicar-icu-a-multicentre-open-label-randomised-controlled-phase-3-trial
#11
Samir Jaber, Catherine Paugam, Emmanuel Futier, Jean-Yves Lefrant, Sigismond Lasocki, Thomas Lescot, Julien Pottecher, Alexandre Demoule, Martine Ferrandière, Karim Asehnoune, Jean Dellamonica, Lionel Velly, Paër-Sélim Abback, Audrey de Jong, Vincent Brunot, Fouad Belafia, Antoine Roquilly, Gérald Chanques, Laurent Muller, Jean-Michel Constantin, Helena Bertet, Kada Klouche, Nicolas Molinari, Boris Jung
BACKGROUND: Acute acidaemia is frequently observed during critical illness. Sodium bicarbonate infusion for the treatment of severe metabolic acidaemia is a possible treatment option but remains controversial, as no studies to date have examined its effect on clinical outcomes. Therefore, we aimed to evaluate whether sodium bicarbonate infusion would improve these outcomes in critically ill patients. METHODS: We did a multicentre, open-label, randomised controlled, phase 3 trial...
July 7, 2018: Lancet
https://www.readbyqxmd.com/read/29908974/severe-infrarenal-atheroma-load-in-open-aortic-aneurysm-repair-is-not-a-risk-factor-for-postoperative-acute-kidney-injury
#12
Sophie Ooms, Banne Nemeth, Jan Jacob Wever, Bob Knippenberg, Hans van Overhagen, Randolph George Statius van Eps
BACKGROUND: Acute kidney injury (AKI) after open aortic repair is subject to multiple patient- and operation-related variables. Hostile neck morphology in open aneurysm repair is thought to contribute to this AKI risk postoperatively. The aim of this study was to evaluate if large neck atheroma is a possible risk factor in the postoperative development of AKI. METHODS: Retrospectively 137 patients were evaluated for neck atheroma and AKI incidence. Atheroma load measurements were performed by 2 different techniques...
June 15, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29907141/serum-and-urine-fgf23-and-igfbp-7-for-the-prediction-of-acute-kidney-injury-in-critically-ill-children
#13
Zhenjiang Bai, Fang Fang, Zhong Xu, Chunjiu Lu, Xueqin Wang, Jiao Chen, Jian Pan, Jian Wang, Yanhong Li
BACKGROUND: Fibroblast growth factor 23 (FGF23) and insulin-like growth factor binding protein 7 (IGFBP-7) are suggested to be biomarkers for predicting acute kidney injury (AKI). We compared them with proposed AKI biomarker of cystatin C (CysC), and aimed (1) to examine whether concentrations of these biomarkers vary with age, body weight, illness severity assessed by pediatric risk of mortality III score, and kidney function assessed by estimated glomerular filtration rate (eGFR), (2) to determine the association between these biomarkers and AKI, and (3) to evaluate whether these biomarkers could serve as early independent predictors of AKI in critically ill children...
June 15, 2018: BMC Pediatrics
https://www.readbyqxmd.com/read/29891225/acute-kidney-injury-after-pediatric-cardiac-surgery
#14
REVIEW
Shi-Min Yuan
Acute kidney injury (AKI) is a common complication of pediatric cardiac surgery and is associated with increased morbidity and mortality. Literature of AKI after pediatric cardiac surgery is comprehensively reviewed in terms of incidence, risk factors, biomarkers, treatment and prognosis. The novel RIFLE (pediatric RIFLE for pediatrics), Acute Kidney Injury Network (AKIN) and Kidney Disease Improving Global Outcomes (KDIGO) criteria have brought about unified diagnostic standards and comparable results for AKI after cardiac surgery...
March 30, 2018: Pediatrics and Neonatology
https://www.readbyqxmd.com/read/29890966/maternal-near-miss-collection-at-an-australian-tertiary-maternity-hospital
#15
Skandarupan Jayaratnam, Sonia Kua, Caroline deCosta, Richard Franklin
BACKGROUND: Australia has a maternal mortality ratio of 6.8/100000 live births, a rate akin to other developed countries and consistent with the high level care provided within the Australian health care system. With maternal mortality at very low levels assessment of severe maternal morbidity is increasingly being used as an indicator of quality of care and to identify areas for improvement in maternity services. The WHO maternal 'near miss' criteria is a standardised tool has been increasingly used worldwide to assess maternal morbidity and standards of maternity care...
June 11, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29861565/acute-kidney-injury-of-infectious-etiology-in-monsoon-season-a-prospective-study-using-acute-kidney-injury-network-criteria
#16
K Mehta, A Pajai, S Bhurke, A Shirkande, R Bhadade, R D'Souza
The epidemiological pattern of acute kidney injury (AKI) in tropical countries during monsoon reflects infectious disease as the most important cause. AKI is a confounding factor and may be overlooked by primary health-care providers and underreported in health statistics. The present study prospectively helps estimate the burden of disease and analyze etiology, clinical profile, and outcome in a tertiary care hospital of a metropolitan city in a tropical country. The study period included monsoon season of 2012 and 2013, a total of 8 months...
March 2018: Indian Journal of Nephrology
https://www.readbyqxmd.com/read/29799334/stereotactic-body-radiation-therapy-for-benign-spine-tumors-is-dose-de-escalation-appropriate
#17
Ronny Kalash, Scott M Glaser, John C Flickinger, Steven Burton, Dwight E Heron, Peter C Gerszten, Johnathan A Engh, Nduka M Amankulor, John A Vargo
OBJECTIVE Akin to the nonoperative management of benign intracranial tumors, stereotactic body radiation therapy (SBRT) has emerged as a nonoperative treatment option for noninfiltrative primary spine tumors such as meningioma and schwannoma. The majority of initial series used higher doses of 16-24 Gy in 1-3 fractions. The authors hypothesized that lower doses (such as 12-13 Gy in 1 fraction) might provide an efficacy similar to that found with the dose de-escalation commonly used for intracranial radiosurgery to treat acoustic neuroma or meningioma and with a lower risk of toxicity...
August 2018: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/29797191/anthropogenic-activities-impact-on-atmospheric-environmental-quality-in-a-gas-flaring-community-application-of-fuzzy-logic-modelling-concept
#18
Olayiwola Akin Akintola, Abimbola Yisau Sangodoyin, Foluso Oyedotun Agunbiade
We present a modelling concept for evaluating the impacts of anthropogenic activities suspected to be from gas flaring on the quality of the atmosphere using domestic roof-harvested rainwater (DRHRW) as indicator. We analysed seven metals (Cu, Cd, Pb, Zn, Fe, Ca, and Mg) and six water quality parameters (acidity, PO4 3- , SO4 2- , NO3 - , Cl- , and pH). These were used as input parameters in 12 sampling points from gas-flaring environments (Port Harcourt, Nigeria) using Ibadan as reference. We formulated the results of these input parameters into membership function fuzzy matrices based on four degrees of impact: extremely high, high, medium, and low, using regulatory limits as criteria...
August 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29776828/septic-acute-kidney-injury-patients-in-emergency-department-the-risk-factors-and-its-correlation-to-serum-lactate
#19
Yin-Chou Hsu, Chih-Wei Hsu
BACKGROUND: Acute kidney injury (AKI) is a common complication in septic patients, imposing a heavy burden of illness in terms of morbidity and mortality. Serum lactate is a widely used marker predicting the severity of sepsis. A paucity of research has investigated septic AKI in emergency departments (EDs) and its correlation with initial serum lactate level. This study aimed at identifying risk factors for septic AKI and clarifying the link between initial serum lactate level and septic AKI in ED patients...
May 15, 2018: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29724418/acr-appropriateness-criteria-%C3%A2-pretreatment-staging-of-muscle-invasive-bladder-cancer
#20
Christian B van der Pol, V Anik Sahni, Steven C Eberhardt, Aytekin Oto, Oguz Akin, Lauren F Alexander, Brian C Allen, Fergus V Coakley, Adam T Froemming, Pat F Fulgham, Keyanoosh Hosseinzadeh, Jodi K Maranchie, Rekha N Mody, Nicola Schieda, David M Schuster, Aradhana M Venkatesan, Carolyn L Wang, Mark E Lockhart
Muscle-invasive bladder cancer (MIBC) has a tendency toward urothelial multifocality and is at risk for local and distant spread, most commonly to the lymph nodes, bone, lung, liver, and peritoneum. Pretreatment staging of MIBC should include imaging of the urothelial upper tract for synchronous lesions; imaging of the chest, abdomen, and pelvis for metastases; and MRI pelvis for local staging. CT abdomen and pelvis without and with contrast (CT urogram) is recommended to assess the urothelium and abdominopelvic organs...
May 2018: Journal of the American College of Radiology: JACR
keyword
keyword
164832
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"