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Trend tuberculosis

Młgorzata Sadkowska-Todys, Andrzej Zieliński, Mirosław P. Czarkowski
OBJECTIVE OF THE ARTICLE: This is for the year 2016 subsequent annual analysis of the situation of infectious and parasitic diseases in Poland as part of the Epidemiological Chronicle of the Epidemiological Review. Its purpose is to summarize the collective incidence of infectious diseases and to indicate potential threats to the health of populations from communicable diseases occurring in Poland. MATERIAL AND METHODS: The basic source of epidemiological information for this summary is a summary of data from reports of the State Sanitary Inspection, contained in the annual bulletins “Infectious diseases and poisoning in Poland in 2016” and “Protective Vaccination in Poland in 2016” (1, 2)...
2018: Przegla̧d Epidemiologiczny
Mei-Hua Wang, Han-Kun Chen, Min-Huei Hsu, Hui-Chi Wang, Yu-Ting Yeh
BACKGROUND: Outbreaks of several serious infectious diseases have occurred in recent years. In response, to mitigate public health risks, countries worldwide have dedicated efforts to establish an information system for effective disease monitoring, risk assessment, and early warning management for international disease outbreaks. A cloud computing framework can effectively provide the required hardware resources and information access and exchange to conveniently connect information related to infectious diseases and develop a cross-system surveillance and control system for infectious diseases...
August 8, 2018: Journal of Medical Internet Research
Tulshidas S Patil, Ashwini S Deshpande
Tuberculosis (TB) is a disease caused due to an infection of Mycobacterium Tuberculosis (M TB) bacilli affecting millions of people worldwide. It is a 9th leading cause of death and ranks above the HIV/AIDS. The unique intracellular life-cycle, more dangerous drug-resistant forms of bacilli, and insufficient investments in the TB research & development hindered the occurrence of optimum diagnostic, preventive, and treatment strategy against this disease. Areas covered: The aim of this review is to provide an update and overview of the current trends in the diagnosis, prevention, and treatment of the disease...
August 7, 2018: Expert Opinion on Therapeutic Patents
Yao-Chung Liu, Chi-Jung Wu, Po-Shen Ko, Sheng-Hsuan Chien, Nai-Wen Fan, Hao-Yuan Wang, Jyh-Pyng Gau, Chia-Jen Liu, Liang-Tsai Hsiao, Tzeon-Jye Chiou, Chun-Yu Liu, Jin-Hwang Liu
BACKGROUND: Mycobacterial infections are important and potentially life-threatening complications after organ transplantations. Notably, for the recipients of allogeneic hematopoietic stem cell transplantation (HSCT), there are a few supporting results to explore post-transplant mycobacterial infections. Taiwan is a high endemic area of the infection. We aim to investigate the incidence, risk factors, and survival of post-transplant mycobacterial infections, including mycobacterium tuberculosis (MTB) and non-tuberculous mycobacterium (NTM)...
July 26, 2018: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
Madeeha Laghari, Syed Azhar Syed Sulaiman, Amer Hayat Khan, Naheed Memon
Background: Regardless of the advancement in medical technologies, the diagnosis of tuberculosis (TB) in children has remained a challenge. Childhood TB is rampant and an important cause of morbidity and mortality. The objective of this study was to determine the trend of TB and treatment outcomes in children aged ≤14 years registered for TB treatment under DOTS course in three districts of Sindh, Pakistan. Methods: For this retrospective study, records of TB children (≤14 years) registered for the treatment of TB from January 2011 to December 2015 in three districts of Pakistan, were collected...
2018: PeerJ
G Tam, H Yang, T Meyers
INTRODUCTION: Tuberculosis (TB) commonly affects developing countries. Several developed regions in Asian still have a stagnant intermediate TB burden. Information to adequately inform TB strategies is lacking. We conducted a mixed methods study to fill this information gap in Hong Kong. METHODS: Data from the Hong Kong government were used to analyse trends of TB notification rates compared with World Health Organization (WHO) targets. A review of policy documents and literature was conducted to evaluate TB control and elimination in Hong Kong...
July 27, 2018: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
Hyeonseok Kim, Jeong Ha Mok, Bohyoung Kang, Taehoon Lee, Hyun-Kyung Lee, Hang Jea Jang, Yu Ji Cho, Doosoo Jeon
Background/Aims: This study was conducted to evaluate the recent prevalence and trend of anti-tuberculosis (TB) drug resistance with a focus on multidrug-resistance (MDR) and fluoroquinolone resistance in South Korea. Methods: We retrospectively reviewed the drug susceptibility testing results of culture-confirmed Mycobacterium tuberculosis isolates collected from 2010 to 2014 at seven tertiary hospitals in South Korea. Results: A total of 5,599 cases were included: 4,927 (88...
July 27, 2018: Korean Journal of Internal Medicine
Rodolfo Augusto Bacelar de Athayde, Fábio Eiji Arimura, Ronaldo Adib Kairalla, Carlos Roberto Ribeiro Carvalho, Bruno Guedes Baldi
OBJECTIVE: Pulmonary alveolar proteinosis (PAP) is a rare disease, characterized by the alveolar accumulation of surfactant, which is composed of proteins and lipids. PAP is caused by a deficit of macrophage activity, for which the main treatment is whole-lung lavage (WLL). We report the experience at a referral center for PAP in Brazil. METHODS: This was a retrospective study involving patients with PAP followed between 2002 and 2016. We analyzed information regarding clinical history, diagnostic methods, treatments, and outcomes, as well as data on lung function, survival, and complications...
May 2018: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
A N Gupte, V Mave, S Meshram, R Lokhande, D Kadam, S Dharmshale, R Bharadwaj, A Kagal, N Pradhan, S Deshmukh, S Atre, T Sahasrabudhe, M Barthwal, S Meshram, A Kakrani, V Kulkarni, S Raskar, N Suryavanshi, R Shivakoti, S Chon, E Selvin, N Gupte, A Gupta, J E Golub
SETTING: The optimal timing of screening for diabetes mellitus (DM) among tuberculosis (TB) cases is unclear due to the possibility of stress hyperglycemia. DESIGN: We evaluated adult (18 years) pulmonary TB cases at treatment initiation as well as at 3 months, 6 months and 12 months. DM was identified by self-report (known DM) or glycated hemoglobin (HbA1c)  6.5% (new DM). Trends in HbA1c levels during treatment were assessed using non-parametric tests. RESULTS: Of the 392 participants enrolled, 75 (19%) had DM, 30 (40%) of whom had new DM...
July 1, 2018: International Journal of Tuberculosis and Lung Disease
Hamufare Mugauri, Hemant Deepak Shewade, Riitta A Dlodlo, Sithokozile Hove, Edwin Sibanda
OBJECTIVE: To quantify and assess trends and risk factors for loss to follow-up (LTFU) and delays before treatment initiation among bacteriologically-confirmed pulmonary tuberculosis (TB) patients (laboratory-diagnosed) in Bulawayo, 2012-16. DESIGN: Cohort study using secondary programme data. Presumptive TB patients' sputum samples were sent to the laboratory from the 19 primary health care clinics. Laboratory-diagnosed patients (microscopy or Xpert MTB/RIF) were tracked for treatment registration at the clinics...
July 17, 2018: International Journal of Infectious Diseases: IJID
Kyungjong Kim, Jeong Seong Yang, Hongjo Choi, Heejin Kim, Sang-Hee Park, Se-Mi Jeon, Na-Ra Lim, Chang Ki Kim
Molecular epidemiological data are needed to assess tuberculosis (TB)-management policy outcomes in South Korea. IS6110 restriction fragment-length polymorphism (IS6110-RFLP) and mycobacterial interspersed repetitive unit-variable-number tandem repeat (MIRU-VNTR) analyses are major molecular epidemiological tools for investigating the transmission or reactivation of active TB. Here, we determined trends in the clustering rate (i.e., the prevalence of Mycobacterium tuberculosis isolates with identical genotype patterns) of active TB and related differences between the 1990s and 2000s in Korea...
July 2018: Tuberculosis
Erin Logan, Angelique Kany Kany Luabeya, Humphrey Mulenga, Dunja Mrdjen, Cynthia Ontong, Adam F Cunningham, Michele Tameris, Helen McShane, Thomas J Scriba, William G C Horsnell, Mark Hatherill
Background: It is unclear whether antibodies can prevent Mycobacterium tuberculosis ( Mtb ) infection. In this study, we examined the relationship between total plasma IgG levels, IgG elicited by childhood vaccines and soil-transmitted helminths, and Mtb infection prevalence, defined by positive QuantiFERON (QFT) test. Methods: We studied 100 Mtb uninfected infants, aged 4-6 months. Ten infants (10%) converted to positive QFT test (QFT+) within 2 years of follow-up for Mtb infection...
2018: Frontiers in Immunology
(no author information available yet)
Ahead of Print article withdrawn by publisher. This withdrawal is for above article due to the misoperation of advance online publication.
July 15, 2018: Bioscience Trends
Kim Bloch, Leigh F Johnson, Mlindeli Nkosi, Rodney Ehrlich
BACKGROUND: Despite their burden of a triple epidemic of silicosis, tuberculosis and HIV infection, little is known about the mortality experience of miners from the South African mining industry once they leave employment. Such information is important because of the size and dispersion of this population across a number of countries and the progressive nature of these diseases. METHODS: This study included 306,297 South African miners who left the industry during 2001-2013...
July 11, 2018: BMC Public Health
Y Q Chen, J Du, Y H Liu, Z G Sun, Y Ma, W Shu, X Y Lyu, X Z Tian, L Li, W W Gao
Objective: To study the relationship between the weight change trend of initial treatment patients with pulmonary tuberculosis and the dose change trend of isoniazid, and therefore to analyze the appropriate dose of isoniazid. Methods: Data of initial treatment inpatients with pulmonary tuberculosis from May 1955 to December 2012 were retrospectively analyzed. Elderly patients with pulmonary tuberculosis, patients with drug-resistant tuberculosis, extrapulmonary tuberculosis and those with complications were excluded from the study...
July 12, 2018: Chinese Journal of Tuberculosis and Respiratory Diseases
Spase Petkoski, J Matias Palva, Viktor K Jirsa
Architecture of phase relationships among neural oscillations is central for their functional significance but has remained theoretically poorly understood. We use phenomenological model of delay-coupled oscillators with increasing degree of topological complexity to identify underlying principles by which the spatio-temporal structure of the brain governs the phase lags between oscillatory activity at distant regions. Phase relations and their regions of stability are derived and numerically confirmed for two oscillators and for networks with randomly distributed or clustered bimodal delays, as a first approximation for the brain structural connectivity...
July 2018: PLoS Computational Biology
Bijay Maharjan, Hom Nath Chalise, Mamta Thapa
Ageing population is attributable to the growing trend of diabetes mellitus. Diabetic patients are three times greater risk of developing tuberculosis. The review aims to describe the state of tuberculosis and diabetes mellitus comorbidity, risk factors for the comorbidity from the perspective of the ageing in Nepal. It is a systematic narrative review of literature in Google Scholar and Pubmed. At first, title and abstract of an article was reviewed for relevance, and then full article was reviewed for validity...
July 3, 2018: Journal of Nepal Health Research Council
J Hongler, J Musaazi, B Ledergerber, N Eberhard, C Sekaggya-Wiltshire, P M Keller, J Fehr, B Castelnuovo
OBJECTIVES: The aim of the study was to clarify how HIV infection affects tuberculosis liquid and solid culture results in a resource-limited setting. METHODS: We used baseline data from the Study on Outcomes Related to Tuberculosis and HIV Drug Concentrations in Uganda (SOUTH), which included 268 HIV/tuberculosis (TB)-coinfected individuals. Culture results from Löwenstein-Jensen (LJ) solid culture and mycobacteria growth indicator tube (MGIT) liquid culture systems and culture-based correlates for bacillary density from the sputum of HIV/TB-coinfected individuals at baseline were analysed...
July 3, 2018: HIV Medicine
A González-García, L Carpintero, J Fortún, E Navas-Elorza, P Martín-Dávila, S Moreno
OBJECTIVE: Although the incidence of human immunodeficiency virus (HIV)-associated tuberculosis (TB) has decreased, changes in other characteristics of the disease are largely unknown. To describe the trends in TB in patients infected with HIV from 1995 to 2013. METHODS: We review all cases of TB in a tertiary hospital in Madrid, Spain. RESULTS: Among 1,284 patients diagnosed of TB, 298 (23%) were coinfected with HIV. The prevalence of HIV infection during the period of study has decreased from 40% to 14% (p for the trend < 0...
August 2018: Revista Española de Quimioterapia: Publicación Oficial de la Sociedad Española de Quimioterapia
A R Allen, R A Skuce, A W Byrne
Successful eradication schemes for bovine tuberculosis (bTB) have been implemented in a number of European and other countries over the last 50 years. However, the islands of Britain and Ireland remain a significant aberration to this trend, with the recent exception of Scotland. Why have eradication schemes failed within these countries, while apparently similar programs have been successful elsewhere? While significant socio-economic and political factors have been discussed elsewhere as key determinants of disease eradication, here we review some of the potential ecological and epidemiological constraints that are present in these islands relative to other parts of Europe...
2018: Frontiers in Veterinary Science
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