keyword
https://read.qxmd.com/read/38522980/patient-provider-lung-cancer-screening-discussions-an-analysis-of-a-national-survey
#21
JOURNAL ARTICLE
Niki Nourmohammadi, Trinity Hsiao Pei Liang, Gelareh Sadigh
BACKGROUND: The US Preventative Service Task Force (USPSTF) updated lung cancer screening (LCS) recommendations with annual low-dose CT (LDCT) in 2021. We aimed to assess prevalence of patient-provider discussion about LCS and determine its associated factors. MATERIALS AND METHODS: Using data from Health Information National Trends Survey (HINTS) 2022 cycle 6, 2 cohorts were evaluated: (1) potentially LCS-eligible, included participants at least 50 years old with a history of smoking and no prior history of lung cancer; (2) LCS-ineligible individuals based on age (eg, 18-49 years old), smoking history (eg, never smoked), or history of lung cancer...
March 2, 2024: Clinical Lung Cancer
https://read.qxmd.com/read/38522790/acute-macrocystic-thoracic-schwannoma-systematic-review-and-illustrative-case-example
#22
REVIEW
Grace R Fassina, Spencer J Oslin, Helen H Shi, John F Burke, Caple A Spence, Christopher S Graffeo
BACKGROUND: Schwannomas are benign peripheral nerve sheath tumors arising from myelinating Schwann cells. Although macrocystic changes are regularly encountered in schwannoma variants such as vestibular nerve tumors, they are exceedingly rare among spinal neoplasms. METHODS: Case report and systematic review of four databases (Ovid Medline, PubMed, Science Direct, and SCOPUS) from inception to present. All peer-reviewed publications reporting intradural cystic thoracic schwannoma were included...
March 22, 2024: World Neurosurgery
https://read.qxmd.com/read/38522492/genetic-characteristics-of-blastocystis-sp-in-cattle-from-hebei-province-china
#23
JOURNAL ARTICLE
Yuxin Sun, Hui-Zhu Nan, Chao Zhang, Xin Yang, Yan Zhao, Gang Feng, Lei Ma
Blastocystis sp. is a protozoan parasite that infects the intestines of humans and animals, causing chronic diseases such as skin rashes, abdominal pain, and irritable bowel syndrome. A survey was conducted to determine the prevalence and genetic diversity of Blastocystis sp. infection in cattle, in Hebei Province, China. 2746 cattle fecal samples were collected from 11 cities in Hebei Province and analyzed using polymerase chain reaction targeting the Blastocystis sp. barcoding gene. MEGA, PhyloSuite, and PopART were used to analyze the subtype, sequence signature, pairwise genetic distance, and genetic diversity indices...
March 22, 2024: Microbial Pathogenesis
https://read.qxmd.com/read/38522304/novel-technique-to-improves-graft-unfolding-in-vitrectomized-eyes-during-descemet-membrane-endothelial-keratoplasty
#24
Majed Alkharashi, Wael Otaif
INTRODUCTION: Descemet membrane endothelial keratoplasty (DMEK) is commonly used to treat endothelial pathologies in bicameral pseudophakic eyes with a normal depth of the anterior chamber. However, performing this procedure on eyes that have undergone vitrectomy carries a higher risk of complications. Therefore, this report presents a novel technique for improving the unfolding of a DMEK graft in a vitrectomized eye. PRESENTATION OF CASE: A 49-year-old man with a history of complicated cataract surgery one year prior was referred to our clinic with pseudophakic bullous keratopathy in his left eye...
March 15, 2024: International Journal of Surgery Case Reports
https://read.qxmd.com/read/38521838/hypercalcemia-as-a-rare-manifestation-of-immune-reconstitution-inflammatory-syndrome-iris-in-a-person-living-with-human-immunodeficiency-virus-hiv-with-disseminated%C3%A2-nontuberculous-mycobacteriosis
#25
JOURNAL ARTICLE
Maximilian Webendoerfer, Margarethe Konik, Markus Zettler, Johannes Wienker, Josefine Rawitzer, Stefan Esser, Jan Kehrmann, Ken Herrmann, Hans Christian Reinhardt, Oliver Witzke, Sebastian Dolff
INTRODUCTION: Granulomatosis due to immune reconstitution inflammatory syndrome (IRIS) and disseminated Mycobacterium avium-intracellulare (M. avium) infection may trigger hypercalcemia. Here, we report a rare case of hypercalcemia and acute kidney damage related to IRIS in a person living with Human Immunodeficiency Virus (HIV). CASE PRESENTATION: A 39-year-old male person living with HIV presented with muscle weakness and unwanted weight loss of 8 kg within the last 2 weeks...
March 23, 2024: Infection
https://read.qxmd.com/read/38520891/longitudinal-vaginal-septum-with-normal-uterus-and-cervix-a-case-report
#26
Surahman Hakim, Fernandi Moegni, I Gede Manu Mahendra, Gracia Natalia Theresia
INTRODUCTION AND IMPORTANCE: Longitudinal vaginal septum is usually associated with uterine anomalies, such as septate uterus and didelphys uterus. Normal uterus and cervix found in longitudinal vaginal septum is a rare case but can affect sexual activities and reproductive outcomes. CASE PRESENTATION: We present a case of a 42-year-old woman with a history of primary infertility for 7 years was referred by the endocrinology division due to the presence of a longitudinal vaginal septum and difficulty in performing intrauterine insemination...
March 19, 2024: International Journal of Surgery Case Reports
https://read.qxmd.com/read/38520745/osimertinib-in-patients-with-treatment-naive-egfr-mutant-non-small-cell-lung-cancer-overall-survival-post-progression-management-and-budget-impact-analysis-in-real-world
#27
JOURNAL ARTICLE
Giulia Pasello, Martina Lorenzi, Daniela Scattolin, Alessandro Del Conte, Fabiana Cecere, Alberto Pavan, Marianna Macerelli, Valentina Polo, Sara Pilotto, Mariacarmela Santarpia, Enrico Cumerlato, Valentina Da Ros, Giada Targato, Alberto Bortolami, Laura Bonanno, Alessandra Ferro, Alessandro Dal Maso, Stefano Frega, Valentina Guarneri
INTRODUCTION: The observational multicenter prospective FLOWER study (NCT04965701) confirmed effectiveness and safety of osimertinib in the real-world (RW) management of untreated EGFR-mutant advanced non-small cell lung cancer (aNSCLC) patients. METHODS: Herein, we report updated survival data, post-progression management, cost/effectiveness and budget impact (BI) of osimertinib compared with a RW population receiving gefitinib or erlotinib. RESULTS: Overall, 189 Caucasian patients receiving first-line osimertinib were included...
March 23, 2024: Oncologist
https://read.qxmd.com/read/38520121/incremental-net-monetary-benefit-of-using-varenicline-for-smoking-cessation-a-systematic-review-and-meta-analysis-of-economic-evaluation-studies
#28
REVIEW
Chayutthaphong Chaisai, Chanthawat Patikorn, Kednapa Thavorn, Shaun Wen Huey Lee, Nathorn Chaiyakunapruk, Sajesh K Veettil
AIMS: To conduct a systematic review and meta-analysis and pool the incremental net benefits (INBs) of varenicline compared with behaviour support with bupropion or nicotine replacement therapy (NRT), behaviour support alone and unaided cessation in adult smokers making a first-time attempt to quit. METHODS: A search for economic evaluation studies was conducted from inception to 30 September 2022, on PubMed, Embase, Cost-Effectiveness Analysis (CEA) Registry by Tufts Medical Centre, EconLit and the NHS Economic Evaluation Database (NHS EED)...
March 22, 2024: Addiction
https://read.qxmd.com/read/38519388/female-fertility-cryopreservation-outcomes-in-childhood-cancer-a-systematic-review
#29
REVIEW
Srinithya R Gillipelli, Luca Pio, Paul D Losty, Abdelhafeez H Abdelhafeez
BACKGROUND AND AIMS: As survival rates in childhood cancer progress significantly, health outcomes in adulthood are pivotal to quality of life (QoL). Female patients undergoing chemotherapy and radiation for childhood cancer may experience adverse effects such as gonadotoxicity-related ovarian insufficiency. Ovarian tissue cryopreservation (OTC) is well studied in adults, but has only recently started to be explored in an effort to preserve fertility in young patients with childhood cancer...
March 1, 2024: Journal of Pediatric Surgery
https://read.qxmd.com/read/38519014/changes-in-heart-transplant-outcomes-of-elderly-patients-in-the-new-allocation-era
#30
JOURNAL ARTICLE
Zachary W Sollie, Jennie H Kwon, Benjamin Usry, Khaled Shorbaji, Brett A Welch, Zubair A Hashmi, Lucas Witer, Nicolas Pope, Ryan J Tedford, Arman Kilic
INTRODUCTION: Studies demonstrate that heart transplantation (HT) can safely be performed in septuagenarians. We evaluate outcomes of septuagenarians undergoing HT after the US heart allocation change in 2018. METHODS: The United Network for Organ Sharing (UNOS) registry was used to identify ≥70 years old HT between 2010-2021. Primary outcomes were 90-day and 1-year mortality. Kaplan-Meier, multivariable Cox proportional hazards, and accelerated failure time models were used for unadjusted and risk-adjusted analyses...
March 20, 2024: Journal of Thoracic and Cardiovascular Surgery
https://read.qxmd.com/read/38518436/the-perceived-mental-health-experiences-and-needs-of-postpartum-mothers-living-in-the-united-arab-emirates-a-focus-group-study
#31
JOURNAL ARTICLE
Nivine Hanach, Hadia Radwan, Wegdan Bani Issa, Roba Saqan, Nanne de Vries
BACKGROUND: After childbirth, mothers are particularly vulnerable to mental health problems including anxiety and depression, which often remain undetected and untreated. In the United Arab Emirates (UAE), recent figures revealed a substantial prevalence of postpartum depression. However, postpartum mental health remains largely understudied in the country's clinical and research settings. Therefore, given the paucity of literature in the UAE and building upon previous epidemiological findings, this study aimed to explore the perceived mental health experiences and needs of mothers during the postpartum period to guide the development of targeted interventions that address mothers' unique mental health challenges...
March 18, 2024: Midwifery
https://read.qxmd.com/read/38517269/the-seroepidemiology-of-immunoglobulin-g-antibodies-against-pertussis-toxin-and-filamentous-hemagglutinin-in-the-east-of-china-during-the-covid-19-pandemic
#32
JOURNAL ARTICLE
Xiang Sun, Tingting Zhang, Jinning Sun, Juan Zhou, Qiang Chen, Chengmei Jia, Yan Xu, Yun Wu, Zhiguo Wang, Wen Wang
This study employed sero-epidemiological methods to estimate the incidence of pertussis within a healthy population located in eastern China. The aim was to gain deeper insights into the epidemiological characteristics and burden of pertussis within the country. Blood samples were collected from healthy individuals in Jiangsu Province between June 2019 and December 2022. The levels of IgG antibodies against pertussis toxin (anti-PT) and filamentous hemagglutinin (anti-FHA) in the serum were quantitatively measured using enzyme-linked immunosorbent assay (ELISA)...
December 31, 2024: Human Vaccines & Immunotherapeutics
https://read.qxmd.com/read/38516684/multi%C3%A2-omics-approach-to-improve-patient%C3%A2-tailored-therapy-using-immune-checkpoint-blockade-and-cytokine%C3%A2-induced-killer-cell-infusion-in-an-elderly-patient-with-lung-cancer-a-case-report-and-literature-review
#33
Yasi Xing, Fangyuan Qin, Lei Han, Jingwen Yang, Hongrui Zhang, Yong Qi, Shichun Tu, Yaping Zhai
The 5-year survival rate of patients with advanced non-small cell lung cancer (NSCLC) remains low, despite recent advances in targeted therapy and immunotherapy. Therefore, there is a need to identify alternative strategies to improve treatment outcomes. Modern diagnostics can significantly facilitate the selection of treatment plans to improve patient outcomes. In the present study, multi-form diagnostic methodologies were adopted, including next-generation sequencing-based actionable gene sequencing, programmed death ligand 1 (PD-L1) immunohistochemistry, a circulating tumor cell (CTC) assay, flow cytometric analysis of lymphocyte subsets and computed tomography, to improve disease management in an 86-year-old female patient with relapsed metastatic NSCLC...
May 2024: Oncology Letters
https://read.qxmd.com/read/38516681/association-between-different-regional-lymph-node-metastases-of-papillary-thyroid-carcinoma-in-adolescents-and-young-adults
#34
JOURNAL ARTICLE
Lili Wang, Yahua Zheng, Yingpeng Ye, Zhekang Jiang, Jinling Lu, Gaoxiang Chen
Adolescents and young adults (AYA) describe the demographic aged between 15-39 years diagnosed with cancer. This group is particularly at risk of papillary thyroid carcinoma (PTC) with a greater severity compared with other ages. Through comparative design, the present study aimed to quantify central lymph node metastasis (CLNM) risk in AYAs. A total of 463 AYA patients with PTC and 489 patients >39 years old with PTC from Ningbo Medical Center Lihuili Hospital (Ningbo, China) were enrolled. Details such as demographic data, serum indices and fine-needle aspiration from the Electronic Medical Records System were extracted and analyzed...
May 2024: Oncology Letters
https://read.qxmd.com/read/38516680/diagnosis-and-comprehensive-treatment-of-a-glucagonoma-in-a-patient-with-residual-intrahepatic-metastases-postoperatively-a-case-report-and-literature-review
#35
Shenghui Yu, Muxi Ge, Cheng Zhang, Lang Chen, Lei Zhao
Glucagonomas are rare neuroendocrine neoplasms of the pancreas with malignant potential. At present, their epidemiology is not entirely clear, so clinicians are not well versed, lacking any consensus on diagnosis or comprehensive treatment. The present study reports the case of a 32-year-old woman hospitalized for recurrent glossitis, perioral dermatitis and necrolytic migratory erythema (NME) of both lower limbs. Imaging studies revealed a low-density nodule (~2 cm) in the tail of the pancreas, as well as multiple space-occupying hepatic lesions...
May 2024: Oncology Letters
https://read.qxmd.com/read/38516435/dyke-davidoff-masson-syndrome-as-a-rare-cause-of-cerebral-hemiatrophy-insights-from-a-case-series
#36
Praveen K Sharma, Afwaan Faizal, Ajay Lucas Rubben Prabhu, Iffath Misbah
Dyke-Davidoff-Masson syndrome (DDMS) is an uncommon neurological condition marked by changes in the skeletal structure, cerebral hemiatrophy, and ventriculomegaly. Manifesting primarily in early life, DDMS presents with seizures, hemiplegia, facial asymmetry, and intellectual disabilities. There are congenital and acquired types of DDMS, with ischemia being the most common cause of the latter. Three cases are presented here to highlight the radiological and clinical characteristics of DDMS. The first case involves a 27-year-old male with generalized seizures and right-sided hemiparesis since childhood, along with developmental delays and facial asymmetry...
February 2024: Curēus
https://read.qxmd.com/read/38515418/-clinical-observation-of-different-intramedullary-fixation-methods-for-the-treatment-of-intertrochanteric-fracture
#37
JOURNAL ARTICLE
Li-Kun Jin, Ye Li, Jie Zhang, Yan-Xu Dong, Yue-Feng Qi
OBJECTIVE: To explore clinical efficacy of proximal femoral nail anti-rotation(PFNA),InterTan and proximal femoral bionic intramedullary nail (PFBN) in treating femoral intertrochanteric fracture. METHODS: Clinical data of 120 patients with intertrochanteric fracture who were underwent closed reduction intramedullary nail-internal fixation from January 2020 to January 2021 were retrospectively analyzed. According to methods of internal fixation,patients were divided into 3 groups...
March 25, 2024: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://read.qxmd.com/read/38515412/-clinical-comparative-study-on-resection-and-non-resection-of-the-fifth-metatarsal-to-rheumatoid-forefoot-deformity
#38
JOURNAL ARTICLE
Run Tang, Jie Yang, Xiao-Jun Liang, Yi Li, Jun-Hu Wang, Cheng-Yi Liu
OBJECTIVE: To explore clinical effect of the fifth metatarsal head excision and non-excision in rheumatoid arthritis (RA) forefoot deformity reconstruction. METHODS: Retrospective analysis was performed on 50 patients (76 feet) with moderate to severe forefoot deformity caused by RA treated from May 2015 to January 2019. According to degeneration of the fifth metatarsophalangeal joint,the fifth metatarsal head was retained or excised by wind-like forefoot reconstruction,and divided into the fifth metatarsal head preservation group (preservation group) and the fifth metatarsal head resection group (resection group)...
March 25, 2024: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://read.qxmd.com/read/38515411/-a-multicenter-clinical-study-on-the-treatment-of-lateral-epicondylitis-of-humerus-by-manipulation
#39
JOURNAL ARTICLE
Xiao-Zhou Hou, Jing Yin, Hai-Yang Wang, Jin-Yu Gu, Tian-Hao Wan, Man-Hong Yang, Di Xia, Qing Zhang
OBJECTIVE: To investigate clinical effect of tendons pulling,poking and kneading for the treatment of external humeral epicondylitis. METHODS: From January 2018 to December 2021,a multicenter randomized controlled study was performed to collect 192 patients with external humeral epicondylitis in Wangjing Hospital,Beijing Dianli Hospital,and Beijing Fengsheng Osteotraumatology Hospital,respectively,and they were divided into treatment group and control group by random number table method...
March 25, 2024: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://read.qxmd.com/read/38515408/-effect-and-complication-among-different-kinds-of-spinal-endoscopic-surgery-for-lumbar-disc-herniation
#40
JOURNAL ARTICLE
Kang Chen, Fu-Guo Yang, Yuan-Chao Luo, Ren-Jian He
OBJECTIVE: To compare clinical efficacy and complication rate of percutaneous endoscopic transforaminal discectomy(PETD),percutaneous endoscopic interlaminar discectomy (PEID) and unilateral biportal endoscopic (UBE) in treating single-segment lumbar disc herniation(LDH). METHODS: From October 2019 to August 2021,121 LDH patients with single-segment treated by spinal endoscopy were retrospectively analyzed and divided into three groups. In PETD group,there were 48 patients,including 19 males and 29 females,aged from 18 to 72 years old with an average of (44...
March 25, 2024: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
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