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https://www.readbyqxmd.com/read/30121738/whose-blood-is-it-application-of-deparray%C3%A2-technology-for-the-identification-of-individual-s-who-contributed-blood-to-a-mixed-stain
#1
K Anslinger, B Bayer
The interpretation and statistical evaluation of mixed DNA profiles often presents a particular challenge in forensic DNA investigations. Only in specific combinations can single cellular components of a mixture be assigned to one contributor. In this study, the DEPArray™ technology, which enables image-assisted immunofluorescent-sorting of rare single cells using dielectrophoretic (DEP) forces, was applied together with different preliminary tests to identify the individual/s who contributed blood to a given mixture...
August 18, 2018: International Journal of Legal Medicine
https://www.readbyqxmd.com/read/30121203/a-27-year-old-man-with-multiple-cavitary-lung-lesions
#2
Carole Scheifer, Clémence Bor, Marie-Pierre Debray, Noémie Chanson, Marie-Paule Chauveheid, Bruno Gombert, Thomas Papo, Karim Sacré
No abstract text is available yet for this article.
August 16, 2018: Chest
https://www.readbyqxmd.com/read/30121092/transition-in-tobacco-use-stages-and-its-related-factors-in-a-longitudinal-study
#3
Ahmad Khosravi, Mohammad Hassan Emamian, Hassan Hashemi, Akbar Fotouhi
OBJECTIVES: Considering the increase in the non-communicable diseases associated with tobacco use in recent decades in Iran, it is necessary to have a general view of the current condition. This study aimed to identify factors associated with tobacco use and to estimate the probability of a 5-year transition in the stages of tobacco use in an adult population. METHODS: In this study, 5190 people in the 40-64-year-old population of Shahroud (North East of Iran) were interviewed in 2009 and 2014 on tobacco smoking...
August 18, 2018: Environmental Health and Preventive Medicine
https://www.readbyqxmd.com/read/30119621/living-liver-donor-with-fasciola-hepatica-first-case-report-in-the-literature
#4
Sami Akbulut, Tevfik Tolga Sahin, Mehmet Kolu, Burak Isik, Yasar Bayindir, Sezai Yilmaz
The major advantage of preoperative magnetic resonance cholangiopancreatography is that living liver donor candidates with complicated biliary tracts may not be exposed to unnecessary laparotomy. To the best of our knowledge, the case presented here features a condition so far not seen by the Liver Transplantation Society. A 27-year-old woman who presented to our clinic as a living liver donor candidate was evaluated but did not have a preoperative magnetic resonance cholangiopancreatography due to technical factors...
August 17, 2018: Experimental and Clinical Transplantation
https://www.readbyqxmd.com/read/30118814/timing-and-modes-of-death-after-pediatric-out-of-hospital-cardiac-arrest-resuscitation
#5
Geneviève Du Pont-Thibodeau, Michael Fry, Matthew Kirschen, Nicholas S Abend, Rebecca Ichord, Vinay M Nadkarni, Robert Berg, Alexis Topjian
AIM: To determine the timing and modes of death of children admitted to a pediatric critical care unit (PICU) of a tertiary care center after an out-of-hospital cardiac arrest (OHCA). METHODS: This is a retrospective descriptive study at a tertiary care PICU of all consecutive patients <18 years old who received ≥ 1 minute of chest compressions, had return of spontaneous circulation (ROSC) for ≥ 20 minutes, and were admitted to the PICU after an OHCA...
August 14, 2018: Resuscitation
https://www.readbyqxmd.com/read/30118736/primary-peritoneal-epithelioid-mesothelioma-of-clear-cell-type-with-a-novel-vhl-gene-mutation-a-case-report
#6
Alexandria Smith-Hannah, Rana Naous
Clear cell variant of epithelioid mesothelioma is an extremely rare tumor with only isolated cases reported so far in the peritoneum. Here, we report a case of peritoneal epithelioid mesothelioma, clear cell variant, in a 63-year-old female patient with a novel VHL gene mutation and an unusual indolent clinical course. The patient, who has no clinical history of asbestos exposure, presented with a 27.2 cm upper abdominal mass and a 5.5 cm liver lesion. Retrospective review of the patient's abdominal CT scan 4 years ago showed two small abdominal lesions that were felt clinically to represent hemangiomas...
August 14, 2018: Human Pathology
https://www.readbyqxmd.com/read/30118188/reducing-classroom-temperature-in-a-tropical-climate-improved-the-thermal-comfort-and-the-performance-of-elementary-school-pupils
#7
José Alí Porras-Salazar, David P Wyon, Beatriz Piderit-Moreno, Sergio Contreras-Espinoza, Pawel Wargocki
A two-week long intervention study was performed in two classrooms in an elementary school in Costa Rica. Split-cooling air conditioning (AC) units were installed in both classrooms. During the first week, the air temperature was reduced in one classroom while in the other (placebo) classroom the fans were operated but no cooling was provided. During the second week, the conditions were exchanged to create a 2x2 crossover design in which each pupil was their own control. A total of 37 children performed tasks similar to school work and completed questionnaires reporting their thermal sensation and perceptions...
August 17, 2018: Indoor Air
https://www.readbyqxmd.com/read/30116625/outcomes-of-wound-dehiscence-after-penetrating-keratoplasty-and-lamellar-keratoplasty
#8
Xin Wang, Ting Liu, Sai Zhang, Xiaolin Qi, Suxia Li, Weiyun Shi, Hua Gao
Objective: To investigate the incidence, causes, occurrence time, and range of wound and outcomes of wound dehiscence in patients treated by penetrating keratoplasty (PK) or lamellar keratoplasty (LK). Methods: We retrospectively reviewed medical records of keratoplasty in Shandong Eye Hospital from January 2006 to June 2017. Thirty-one eyes of 30 patients had sustained wound dehiscence (WD) after surgical treatment. The surgical type, causes, occurrence time, extent of the wound, treatment, and outcomes were recorded...
2018: Journal of Ophthalmology
https://www.readbyqxmd.com/read/30116450/ivabradine-versus-beta-blockers-in-mitral-stenosis-in-sinus-rhythm-an-updated-meta-analysis-of-randomized-controlled-trials
#9
John Daniel A Ramos, Elleen L Cunanan, Lauro L Abrahan, Marc Denver A Tiongson, Felix Eduardo R Punzalan
Background: Symptoms of mitral stenosis (MS) are worsened during tachycardia and exercise. Beta-blockers are used in controlling heart rate (HR) in MS, resulting in symptom improvement, but coming with significant side effects. Ivabradine has a selective action on the sinus node devoid of the usual side effects of beta-blockers. Small studies have recently investigated the role of ivabradine in MS in sinus rhythm. Our aim was to determine the efficacy of ivabradine, compared to beta-blockers, in terms of exercise duration, maximum HR achieved, resting HR, mean gradient, and working capacity among patients with MS in sinus rhythm...
August 2018: Cardiology Research
https://www.readbyqxmd.com/read/30115720/tension-haemothorax-from-a-bleeding-branch-of-the-renal-artery-following-isolated-penetrating-thoracic-trauma-a-rare-presentation
#10
Oliver Brunckhorst, Nadia Maria Guidozzi, Leigh R Warren, Christopher J Peters
A 27-year-old man presented to a major trauma centre with two posterolateral thoracic stab injuries over the right scapula and thoracoabdominal junction. He was tachycardic and hypotensive with a chest X-ray revealing a large right-sided tension haemothorax, requiring insertion of two intercostal chest drains. A subsequent CT scan demonstrated a grade 4 right kidney laceration with active back bleeding from a renal artery branch, through a right diaphragmatic defect, into the pleural cavity. Embolisation of the feeding renal vessel controlled the bleeding and avoided the need for a nephrectomy...
August 16, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/30115061/balloon-pulmonary-angioplasty-efficient-therapy-of-chronic-thromboembolic-pulmonary-hypertension-in-the-patient-with-advanced-sarcoidosis-a-case-report
#11
Andrzej Labyk, Dominik Wretowski, Sabina Zybińska-Oksiutowicz, Aleksandra Furdyna, Katarzyna Ciesielska, Dorota Piotrowska-Kownacka, Olga Dzikowska -Diduch, Barbara Lichodziejewska, Andrzej Biederman, Piotr Pruszczyk, Marek Roik
BACKGROUND: Approximately a quarter of patients with advanced sarcoidosis develop pulmonary hypertension (PH), which affects their prognosis. We report unusual case of confirmed chronic thromboembolic pulmonary hypertension (CTEPH) in a patient with stage IV sarcoidosis successfully treated with balloon pulmonary angioplasty (BPA). CASE PRESENTATION: A 65 years old male with a history of colitis ulcerosa, and pulmonary sarcoidosis diagnosed in 10 years before, on long term oral steroids, with a history of deep vein thrombosis and acute pulmonary embolism chronically anticoagulated was referred to our center due to severe dyspnea...
August 16, 2018: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/30114535/demonstration-of-infectious-transgression-through-the-skull-base-occurring-9-years-after-pituitary-adenoma-resection
#12
Jingyi Liu, David L Penn, Ethan Katznelson, Mina G Safain, Ian F Dunn, Edward R Laws
BACKGROUND: Sellar infections represent less than 1% of all sellar lesions and can be life-threatening. These infections occur de novo in up to 70% of patients, or can less commonly develop after surgical treatment of another primary lesion, such as a pituitary adenoma. CASE DESCRIPTION: We report a unique case of a 27 year-old woman with a recurrent pituitary adenoma treated with two prior transsphenoidal resections. She ultimately presented with hypopituitarism, followed by headaches, malaise, chills, and visual field and acuity deficits nine years after her second transsphenoidal resection...
August 13, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/30114344/alterations-in-hub-organization-in-the-white-matter-structural-network-in-toddlers-with-autism-spectrum-disorder-a-2-year-follow-up-study
#13
Lu Qian, Yao Wang, KangKang Chu, Yun Li, ChaoYong Xiao, Ting Xiao, Xiang Xiao, Ting Qiu, YunHua Xiao, Hui Fang, XiaoYan Ke
Little is currently known about the longitudinal developmental patterns of hubs in the whole-brain white matter (WM) structural networks among toddlers with autism spectrum disorder (ASD). This study utilized diffusion tensor imaging (DTI) and deterministic tractography to map the WM structural networks in 37 ASD toddlers and 27 age-, gender- and developmental quotient-matched controls with developmental delay (DD) toddlers aged 2-3 years old at baseline (Time 1) and at 2-year follow-up (Time 2). Furthermore, graph-theoretical methods were applied to investigate alterations in the network hubs in these patients at the two time points...
August 16, 2018: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/30113147/the-prevalence-and-risk-factors-for-diabetic-retinopathy-in-shiraz-southern-iran
#14
Haleh Ghaem, Nima Daneshi, Shirin Riahi, Mostafa Dianatinasab
Globally, diabetic retinopathy (DR) is one of the leading causes of blindness, that diminishes quality of life. This study aimed to describe the prevalence of DR, and its associated risk factors. This cross-sectional study was carried out among 478 diabetic patients in a referral center in Fars province, Iran. The mean±standard deviation age of the participants was 56.64±12.45 years old and DR prevalence was 32.8%. In multivariable analysis, lower education levels (adjusted odds ratio [aOR], 0.43; 95% confidence interval [CI], 0...
August 9, 2018: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/30112169/ozone-therapy-in-conjunction-with-oral-antibiotics-as-a-successful-primary-and-sole-treatment-for-chronic-septic-prosthetic-joint-review-and-case-report
#15
Robert Jay Rowen
The world is facing crisis in management of infectious diseases. The mainstay of treatment has been chemical anti-infectives. These drugs are failing, as superbugs emerge and medicine becomes more sophisticated with treatments such as prosthetic devices, which can harbor bacteria protected by biofilm. This case report describes a 68-year-old woman who received bilateral artificial hips on October 27, 2015. The right hip prosthesis subsequently became septic by June 2016. Three orthopedic surgeons offered her a several month program, which included removal of the prosthesis, implantation of an antibiotic impregnated "spacer" and months of intravenous antibiotics...
April 2018: Medical Gas Research
https://www.readbyqxmd.com/read/30112042/novel-compound-heterozygous-mutations-in-low-density-lipoprotein-receptor-gene-causes-a-severe-phenotype-in-a-chinese-hypercholesterolemia-family
#16
Xinyao Cheng, Yifang Huang, Xueping Qiu, Xiaohuan Cheng, Yalei Jin, Yafei Hu, Bing Yang, Jingbo Zhao, Yuhua Lei, Fang Zheng
Mutations in the low density lipoprotein receptor (LDLR) gene serve a causative role in the pathophysiology of familial hypercholesterolemia (FH), a common autosomal inherited disorder characterized by abnormal lipid metabolism. The aim of the present study was to investigate genetic defects in a Chinese family with FH. Clinical features and family histories were collected, as were the results of various laboratory tests, including determinations of serum lipid concentrations, ultrasonography and angiography results...
August 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/30111934/a-case-of-unusual-occurrence-of-nasogastric-tube-feed-coming-through-the-chest-tube-in-a-27-year-old-polytrauma-patient
#17
Raunaq Chakraborty, Mohd Shoaib Budoo, Sukhyanti Kerai
The provision of early and adequate nutritional support is vital for the successful recovery from the trauma in any form. Nutritional support is enteral unless specified otherwise as dictated by various benefits of the former. Nasogastric tubes provide effective and common mode of enteral feed due to the ease of placement and maintenance. To our knowledge, the late presentation of diaphragmatic hernia with gastric perforation in a trauma patient leading to feed coming through chest tube is very rare of the complications...
July 2018: Indian Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/30111403/-safety-and-efficacy-of-vdmp-re-induction-regimen-in-chinese-children-with-relapsed-acute-lymphoblastic-leukemia-a-report-from-jiangsu-childhood-hematology-group
#18
Jun-Jie Fan, Hai-Long He, Jun Lu, Pei-Fang Xiao, Yi Wan, Yi-Huan Chai, Qi An, Yong-Jun Fang, Shao-Yan Hu
OBJECTIVE: To evaluate the therapeutic safety and efficacy of VDMP re-induction regimen in Chinese children with relapsed acute lymphoblastic leukemia (ALL). METHODS: Forty-one patients with relapsed ALL were prospectively enrolled in this study. All the patients were distributed in 3 children's hospitals and treated with VDMP regimen as the first re-induction chemotherapy. Therapeutic efficacy and side-effects were analyzed. RESULTS: The ratio of male to female was 27:14...
August 2018: Zhongguo Shi Yan Xue Ye Xue za Zhi
https://www.readbyqxmd.com/read/30111079/tuberculosis-in-poland-in-2016
#19
Maria Korzeniewska-Koseła
AIM OF THE STUDY: To evaluate the main features of TB epidemiology in 2016 in Poland and to compare with the situation in the EU/EEA countries. METHODS: Analysis of case- based data on TB patients from National TB Register, data on anti-TB drug susceptibility testing results in cases notified in 2016, data from National Institute of Public Health- National Institute of Hygiene on cases of tuberculosis as AIDS-defining disease, data from Central Statistical Office on deaths from tuberculosis based on death certificates, data from ECDC report „ European Centre for Disease Prevention and Control/WHO Regional Office for Europe...
2018: Przegla̧d Epidemiologiczny
https://www.readbyqxmd.com/read/30110674/uric-acid-as-a-predictor-of-immunoglobulin-a-nephropathy-progression-a-cohort-study-of-1965-cases
#20
Bin Zhu, Dong-Rong Yu, Ji-Cheng Lv, Yi Lin, Qiang Li, Jia-Zhen Yin, Yuan-Yuan Du, Xuan-Li Tang, Li-Chan Mao, Qiu-Fen Li, Yue Sun, Ling Liu, Xian-Fa Li, Dan Fei, Xin-Yi Wei, Cai-Feng Zhu, Xiao-Xia Cheng, Hong-Yu Chen, Yong-Jun Wang
BACKGROUND: The role of serum uric acid (SUA) level in the progression of Immunoglobulin A nephropathy (IgAN) remains controversial. METHODS: In a cohort of 1,965 cases with biopsy-proven IgAN, we examined the associations of SUA concentration with the primary outcome of a composite of all-cause mortality or kidney failure (defined as a reduction of estimated glomerular filtration rate [eGFR] by 40% from baseline, requirements for dialysis and transplantation), or the outcome of kidney failure alone, assessed using Cox and logistic regression models, respectively, with adjustment for confounders...
August 15, 2018: American Journal of Nephrology
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