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Premenopausal osteoporosis

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https://www.readbyqxmd.com/read/28662191/relationship-between-bone-mineral-density-and-alcohol-intake-a-nationwide-health-survey-analysis-of-postmenopausal-women
#1
Hae-Dong Jang, Jae-Young Hong, Kyungdo Han, Jae Chul Lee, Byung-Joon Shin, Sung-Woo Choi, Seung-Woo Suh, Jae-Hyuk Yang, Si-Young Park, Chungwon Bang
OBJECTIVES: Among a variety of relevant factors of osteoporosis, the association between alcohol intake and postmenopausal women's bone mineral density (BMD) by using data from the Korean National Health and Nutrition Examination Survey was evaluated in this study. MATERIALS AND METHODS: Among a total of 31,596 subjects, males, premenopausal women, participants without BMD data were excluded. Finally, a total number of subjects in the study was 3,312. The frequency and amount of alcohol intake were determined by self-reported questionnaires, and BMD was measured by dual-energy x-ray absorptiometry...
2017: PloS One
https://www.readbyqxmd.com/read/28660495/determinants-of-bone-mineral-density-in-young-australian-women-results-from-the-safe-d-study
#2
E T Callegari, S M Garland, A Gorelik, J D Wark
The study aimed to explore determinants of bone parameters in young women. Most bone parameters were associated with height and lean mass. Bone parameters were not associated with vitamin D status. Future research should address whether interventions aimed at improving lean mass are beneficial to bone health in young women. INTRODUCTION: The implementation of prevention strategies during young adulthood may be crucial for osteoporosis prevention in later life, yet literature examining the determinants of bone health in premenopausal women is limited...
June 28, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28566852/correlation-of-mandibular-radiomorphometric-indices-with-serum-calcium-and-serum-estradiol-in-pre-and-post-menopausal-women
#3
Lina Govind Chandak, Vidya Krushnarao Lohe, Rahul R Bhowate, Krushna P Gandhi, Neha V Vyas
BACKGROUND: Osteoporosis is a disease that is seen commonly with increasing age. The purpose of this study was to compare the bone quality of pre- and post-menopausal women using the quantitative indices determined by measurements on panoramic radiographs (mental index, inferior and superior panoramic mandibular indices, antegonion index [AGI], and gonion index) and to determine the effects of serum calcium and serum estradiol levels on alveolar bone loss. MATERIALS AND METHODS: Sixty female patients in the age group of 25-55 years were included in the study...
January 2017: Contemporary Clinical Dentistry
https://www.readbyqxmd.com/read/28509627/impact-of-risk-reducing-salpingo-oophorectomy-in-premenopausal-women
#4
R F M Vermeulen, M van Beurden, C M Korse, G G Kenter
OBJECTIVES: To describe implications of premenopausal risk-reducing salpingo-oophorectomy (RRSO) on quality of life, endocrine symptoms, sexual function, osteoporosis, cardiovascular health, metabolic syndrome, cognitive impairment and safety of hormone replacement therapy. METHODS: We searched the following electronic databases: The Cochrane Library, EMBASE, PsycInfo, and MEDLINE. We selected controlled and uncontrolled trials of premenopausal women undergoing RRSO...
June 2017: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/28490509/vitamin-d-and-calcium-intake-and-risk-of-early-menopause
#5
Alexandra C Purdue-Smithe, Brian W Whitcomb, Kathleen L Szegda, Maegan E Boutot, JoAnn E Manson, Susan E Hankinson, Bernard A Rosner, Lisa M Troy, Karin B Michels, Elizabeth R Bertone-Johnson
Background: Early menopause, defined as the cessation of ovarian function before the age of 45 y, affects ∼10% of women and is associated with higher risk of cardiovascular disease, osteoporosis, and other conditions. Few modifiable risk factors for early menopause have been identified, but emerging data suggest that high vitamin D intake may reduce risk.Objective: We evaluated how intakes of vitamin D and calcium are associated with the incidence of early menopause in the prospective Nurses' Health Study II (NHS2)...
June 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28439060/-calcium-and-bone-metabolism-across-women-s-life-stages-exercise-and-sport-to-increase-bone-strength-in-accordance-with-female-lifecycle
#6
Jun Iwamoto
Among females who require the strategies for preventing osteoporosis, appropriate exercise and sport through all their life are important to increase or maintain bone mass. However, the type of exercise and sport applied to females is different in accordance with the lifecycle. Jumping exercise increases bone mineral content(BMC)in prepubescent children(premenarcheal girls). Bone mineral density(BMD)is higher in adolescent athletes who are engaged in weight-bearing activities. Jumping exercise, muscle strengthening exercise, and weight-bearing plus muscle strengthening exercises increase BMD in young adults and premenopausal women...
2017: Clinical Calcium
https://www.readbyqxmd.com/read/28394826/osteoporosis-in-premenopausal-women
#7
Bente L Langdahl
PURPOSE OF REVIEW: The scope of this review was to review the newest developments in the context of the existing knowledge on premenopausal bone fragility. Fragility fractures are common in postmenopausal women and men and diagnostic criteria for osteoporosis have been agreed and multiple pharmacological treatments have been developed over the last 25 years. In premenopausal women, fragility fractures and very low bone mass are uncommon and osteoporosis in premenopausal women has therefore attracted much less interest...
July 2017: Current Opinion in Rheumatology
https://www.readbyqxmd.com/read/28293690/bone-mineral-density-among-korean-females-aged-20-50%C3%A2-years-influence-of-age-at-menarche-the-korea-national-health-and-nutrition-examination-survey-2008-2011
#8
H K Chang, D-G Chang, J-P Myong, J-H Kim, S-J Lee, Y S Lee, H-N Lee, K H Lee, D C Park, C J Kim, S Y Hur, J S Park, T C Park
To evaluate a possible correlation between bone mineral density (BMD) and age at menarche, the present study used the BMD dataset of the Korea National Health and Nutrition Examination Survey IV-V (KNHANES IV-V). Age at menarche had a small but significant association with BMD of the lumbar spine in premenopausal Korean females, aged 20-50 years. INTRODUCTION: To investigate any correlation between bone mineral density (BMD) and age at menarche in Korean females using data from the fourth and fifth Korea National Health and Nutrition Examination Survey (KNHANES IV-V; 2008-2011)...
March 14, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28218468/igf-1-receptor-expression-on-circulating-osteoblast-progenitor-cells-predicts-tissue-based-bone-formation-rate-and-response-to-teriparatide-in-premenopausal-women-with-idiopathic-osteoporosis
#9
Adi Cohen, Stavroula Kousteni, Brygida Bisikirska, Jayesh G Shah, J Sanil Manavalan, Robert R Recker, Joan Lappe, David W Dempster, Hua Zhou, Donald J McMahon, Mariana Bucovsky, Mafo Kamanda-Kosseh, Julie Stubby, Elizabeth Shane
We have previously reported that premenopausal women with idiopathic osteoporosis (IOP) have profound microarchitectural deficiencies and heterogeneous bone remodeling. Those with the lowest bone formation rate have higher baseline serum insulin-like growth factor-1 (IGF-1) levels and less robust response to teriparatide. Because IGF-1 stimulates bone formation and is critical for teriparatide action on osteoblasts, these findings suggest a state of IGF-1 resistance in some IOP women. To further investigate the hypothesis that osteoblast and IGF-1-related mechanisms mediate differential responsiveness to teriparatide in IOP, we studied circulating osteoblast progenitor (COP) cells and their IGF-1 receptor (IGF-1R) expression...
June 2017: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/28173877/bilateral-ovarian-micrometastatic-adenocarcinoma-upon-prophylactic-oophorectomy-concurrent-with-low-anterior-resection-for-rectal-cancer
#10
Robin Irons, Erin McIntosh, Alexandre Hageboutros, David Warshal, Steven McClane
BACKGROUND: This case report draws attention to the debated role of prophylactic oophorectomy in women undergoing definitive surgical resection of colon and rectal cancers. It can be challenging to discern the indications and appropriate patient population for this procedure based on the current literature. Potential benefits include treatment and prevention of metastatic disease, preventing development of primary ovarian cancer, and prolonging survival. Negative effects include an increase in operative time and potential morbidity, development of osteoporosis, the risk of cardiac events, and decreasing sexual function...
February 7, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28131128/premenopausal-osteoporosis
#11
REVIEW
Adi Cohen
Most premenopausal women with low trauma fracture(s) or low bone mineral density have a secondary cause of osteoporosis or bone loss. Where possible, treatment of the underlying cause should be the focus of management. Premenopausal women with an ongoing cause of bone loss and those who have had, or continue to have, low trauma fractures may require pharmacologic intervention. Clinical trials provide evidence of benefits of bisphosphonates and teriparatide for bone mineral density in several types of premenopausal osteoporosis, but studies are small and do not provide evidence regarding fracture risk reduction...
March 2017: Endocrinology and Metabolism Clinics of North America
https://www.readbyqxmd.com/read/28074252/high-dietary-sodium-intake-is-associated-with-low-bone-mass-in-postmenopausal-women-korea-national-health-and-nutrition-examination-survey-2008-2011
#12
S-J Kwon, Y-C Ha, Y Park
The present cross-sectional study performed using data from the Korea National Health and Nutrition Examination Survey in 9526 women older than 18 years of age demonstrates that high sodium intake is associated with lower bone mineral density and sodium intake ≥2000 mg/day is a risk factor for osteoporosis in postmenopausal women. INTRODUCTION: Several studies have reported that large amount of dietary sodium intake is highly associated with elevated urinary calcium. However, the direct effect of excessive dietary sodium intake on bone mass, as a risk factor for osteoporosis, is still a controversial issue...
January 10, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28074248/pregnancy-associated-osteoporosis-a-case-control-study
#13
P Hadji, J Boekhoff, M Hahn, L Hellmeyer, O Hars, I Kyvernitakis
The etiology and underlying mechanisms of pregnancy-associated osteoporosis (PAO) are still unknown, since no systematic analyses exist. Our results indicate that PAO is a heterogeneous, rare but severe disease including a substantial number of fractures with a significant delay from first symptom to diagnose. INTRODUCTION: Pregnancy-associated osteoporosis (PAO) is a rare but severe type of premenopausal osteoporosis. Most common symptom includes acute lower back pain due to vertebral fracture predominantly occurring in the last trimester of pregnancy or immediately postpartum...
January 10, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28063842/relationship-between-urinary-calcium-and-bone-mineral-density-in-patients-with-calcium-nephrolithiasis
#14
Khashayar Sakhaee, Naim M Maalouf, John Poindexter, Beverley Adams-Huet, Orson W Moe
PURPOSE: Calcium nephrolithiasis is associated with an increased risk of osteoporosis and fracture. Hypercalciuria has been assumed to be pathogenic for bone loss in kidney stone formers, although this association was shown in small cross-sectional studies. We explored the association of urine calcium with bone mineral density in kidney stone formers. MATERIALS AND METHODS: We retrospectively studied bone mineral density in kidney stone formers. Excluded were subjects with hypercalcemia, chronic bowel disease, primary hyperparathyroidism, distal renal tubular acidosis or endogenous creatinine clearance less than 40 ml per minute...
June 2017: Journal of Urology
https://www.readbyqxmd.com/read/28017941/-a-role-of-exercise-and-sports-in-the-prevention-of-osteoporosis
#15
REVIEW
Jun Iwamoto
Physical activity plays an important role in maintaining or enhancing bone health. Jumping exercise increases bone mineral content(BMC)in prepubescent children(premenarcheal girls). Bone mineral density(BMD)is higher in adolescent athletes who are engaged in weight-bearing activities. Jumping exercise, muscle strengthening exercise, and weight-bearing plus muscle strengthening exercises increase BMD in young adults and premenopausal women. Walking, aerobic weight-bearing exercise, muscle strengthening exercise, and weight-bearing plus muscle strengthening exercises maintain or increase BMD in postmenopausal women...
2017: Clinical Calcium
https://www.readbyqxmd.com/read/27846926/low-dairy-calcium-intake-is-associated-with-overweight-and-elevated-blood-pressure-in-polish-adults-notably-in-premenopausal-women
#16
Elżbieta Skowrońska-Jóźwiak, Maciej Jaworski, Roman Lorenc, Małgorzata Karbownik-Lewińska, Andrzej Lewiński
OBJECTIVE: Dietary Ca is now being recognized to play an important role not only in skeletal integrity, but also in the regulation of energy and metabolism. The aim of the present study was to estimate the relationship of dairy Ca intake with BMI and blood pressure (BP) in a sample derived from the Polish population. DESIGN: Ca intake was calculated from an interviewer-administered semi-quantitative FFQ. BMI was calculated from measured weight and height, and BP was measured by a physician...
November 16, 2016: Public Health Nutrition
https://www.readbyqxmd.com/read/27834082/association-between-obesity-and-bone-mineral-density-by-gender-and-menopausal-status
#17
Mohammad Reza Salamat, Amir Hossein Salamat, Mohsen Janghorbani
BACKGROUND: We investigated whether there were gender differences in the effect of obesity on bone mineral density (BMD) based on menopausal status. METHODS: We assessed 5,892 consecutive patients 20 to 91 years old who were referred for dual-energy X-ray absorptiometry (DXA) scans. All subjects underwent a standard BMD scan of the hip (total hip and femoral neck) and lumbar spine (L1 to L4) using a DXA scan and body size assessment. Body mass index was used to categorize the subjects as normal weight, overweight, and obese...
December 2016: Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27825568/osteoarticular-manifestations-of-celiac-disease-and-non-celiac-gluten-hypersensitivity
#18
Stéphanie Dos Santos, Frédéric Lioté
Celiac disease is a chronic inflammatory autoimmune enteropathy based disorder that is triggered by the ingestion of gluten in genetically susceptible individuals. The global prevalence of 1% to 2% represents only the tip of the iceberg. The diagnosis is confirmed by positive specific antibody, anti-transglutaminase or anti-endomysium, specific lesions of the small intestine and a response to strict gluten-free diet. The diagnosis is difficult and often delayed because the clinical variability is very large, ranging from digestive clinical presentation "classic" to "atypical" symptoms, often extra-intestinal, that are sometimes attributed to a concomitant disease or a complication...
May 2017: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/27821086/antineoplastic-treatment-effect-on-bone-mineral-density-in-mexican-breast-cancer-patients
#19
Karina Monroy-Cisneros, Julián Esparza-Romero, Mauro E Valencia, Alfonso G Guevara-Torres, Rosa O Méndez-Estrada, Iván Anduro-Corona, Humberto Astiazarán-García
BACKGROUND: Breast cancer is the most deadly malignancy in Mexican women. Although treatment has improved, it may significantly affect bone mineral status in those who receive it. The aim of this study was to assess the impact of cancer treatment on bone mineral density (BMD) and bone mineral content (BMC), in patients with breast cancer and explore the interaction of menopausal status and clinical stage with cancer treatment on such changes. METHODS: A quasi-experimental design was applied with measurements before and after a chemotherapy treatment in 40 patients with primary diagnosis of invasive breast cancer...
November 8, 2016: BMC Cancer
https://www.readbyqxmd.com/read/27802892/osteoporosis-management-in-patients-with-breast-cancer-emas-position-statement
#20
REVIEW
Florence A Trémollieres, Iuliana Ceausu, Herman Depypere, Irene Lambrinoudaki, Alfred Mueck, Faustino R Pérez-López, Yvonne T van der Schouw, Levent M Senturk, Tommaso Simoncini, John C Stevenson, Petra Stute, Margaret Rees
Aromatase inhibitors (AIs) are the first-line recommended standard of care for postmenopausal estrogen receptor-positive breast cancer. Because they cause a profound suppression of estrogen levels, concerns regarding their potential to increase the risk of fracture were rapidly raised. There is currently a general consensus that a careful baseline evaluation is needed of the risk of fracture in postmenopausal women about to start treatment with AIs but also in all premenopausal women with early disease. Bisphosphonates have been shown in several phase III trials to prevent the bone loss induced by cancer treatment, although no fracture data are available...
January 2017: Maturitas
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