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https://www.readbyqxmd.com/read/28226063/pelvic-floor-rehabilitation-program-report-of-10-years-of-experience
#1
Maria Helena Baena de Moraes Lopes, Juliana Neves da Costa, Júnia Leonne Dourado de Almeida Lima, Lea Dolores Reganhan de Oliveira, Aletha Silva Caetano
Objective: to relate the creation, experience of establishment and service performed in the Pelvic Floor Rehabilitation Program [(PRAP)], a project of the School of Nursing of University of Campinas (UNICAMP), developed at a health unity in Campinas, São Paulo, Brazil. Results: this Program appeared due to the high demand of patients with urinary incontinence (UI) and need of formation or qualification of professionals to serve those customers and multiply the actions at other health unities...
January 2017: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/28225552/potential-clinical-significance-of-perioperative-levels-of-mrna-in-plasma-from-patients-with-cancer-of-the-larynx-or-hypopharynx
#2
Dolores C García-Olmo, J Diego Contreras, María G Picazo, Jesús López-Torres, Damián García-Olmo
BACKGROUND: The use of plasma as a "liquid biopsy" has gained increasing attention. The purpose of the present study was to evaluate the diagnostic and prognostic utility of the perioperative detection and quantitation of mRNAs encoding human telomerase reverse transcriptase (hTERT) and glyceraldehyde 3-phosphate dehydrogenase (GAPDH) in plasma from patients with cancer of the larynx or hypopharynx. METHODS: We recruited 47 patients with laryngeal cancer and 2 patients with hypopharyngeal cancer, plus 27 healthy subjects...
February 22, 2017: Head & Neck
https://www.readbyqxmd.com/read/28220694/selective-fluorogenic-sensing-of-as-iii-using-aptamer-capped-nanomaterials
#3
Mar Oroval, Carmen Coll, Andrea Bernardos, María Dolores Marcos, Ramon Martinez-Manez, Dmitry G Shchukin, Felix Sancenón
Organic-inorganic hybrid nanomaterials offer extremely valuable tools for monitoring many types of analytes in in solution. Within this framework, aptamer-based nanomaterials for heavy metal detection are still very scarce. Herein, a novel sensing nanoprobe for the selective and sensitive detection of As(III) based on the combination of aptamers with mesoporous silica nanoparticles has been developed. The efficiency of the sensor is demonstrated in environmental conditions, showing a great potential in As(III) monitoring assays...
February 21, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28219811/stress-echocardiography-in-patients-who-experienced-mechanical-ventilation-weaning-failure
#4
Manuel Ruiz-Bailén, Jesús Cobo-Molinos, Ana Castillo-Rivera, María Dolores Pola-Gallego-de-Guzmán, Antonio Cárdenas-Cruz, Antonio Martínez-Amat, María Sevilla-Martínez, Clara Hernández-Caballero
INTRODUCTION: Critically ill patients may suffer varying degrees of temporary myocardial dysfunction during respiratory weaning that could play an important role in weaning failure. OBJECTIVES: In this study, we tried to assess the existence of temporary diastolic dysfunction during respiratory weaning. METHODS: Inclusion period is from 2006 to 2015. In this study, we included 181 ventilated patients with cardiogenic shock that were being weaned from mechanical ventilation...
January 18, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28219109/the-use-of-braf-v600e-mutation-specific-immunohistochemistry-in-pediatric-langerhans-cell-histiocytosis
#5
Leomar Y Ballester, Miguel D Cantu, Karen P H Lim, Stephen F Sarabia, Lizmery Suarez Ferguson, C Renee Webb, Carl E Allen, Kenneth L McClain, Carrie A Mohila, Jyotinder N Punia, Angshumoy Roy, Dolores H López-Terrada, M John Hicks, Kevin E Fisher
BRAF p.V600E mutations are detected in greater than 50% of pediatric Langerhans cell histiocytosis (LCH) lesions. However, the use of mutation-specific BRAF V600E immunohistochemistry (IHC) as a surrogate for molecular testing in pediatric LCH is unknown. We tested the mutation-specific BRAF V600E monoclonal antibody (clone VE1) in formalin-fixed, paraffin-embedded LCH samples from 26 pediatric patients (14 males and 12 females, ages 7 mo-17 y) using allele-specific real-time polymerase chain reaction (PCR) with a limit of detection of 0...
February 20, 2017: Hematological Oncology
https://www.readbyqxmd.com/read/28218734/-lesions-detected-in-six-spanish-colorectal-cancer-screening-population-based-programmes-cribea-project-spain
#6
Isabel Portillo Villares, Eunate Arana-Arri, Isabel Idigoras Rubio, Josep Alfons Espinás Piñol, Francisco Pérez Riquelme, Mariola de la Vega Prieto, Alvaro González Aledo, Elena Oceja Setien, Mercedes Vanaclocha Espi, Josefa Ibáñez Cabanell, Dolores Salas Trejo
OBJECTIVE: In this study, the results of six Colorectal Cancer Screening Population Programmes are shown (Catalonia, Valence, Murcia, Cantabria, the Basque Country and the Canary Islands collected between 2005 and 2012. These programmes use the faeces occult blood test (FOBt) biennial. Objective: To determine and compare the results of lesions detected by the programmes, participation, sex, age and test used. METHODS: Retrospective cohort study based on people invited, aged between 50-74 years, in at least a complete round...
February 20, 2017: Revista Española de Salud Pública
https://www.readbyqxmd.com/read/28218439/the-effects-of-exogenous-fatty-acids-and-niacin-on-human-monocyte-macrophage-plasticity
#7
Sergio Montserrat-de la Paz, Dolores Rodriguez, Magdalena P Cardelo, Maria C Naranjo, Beatriz Bermudez, Rocio Abia, Francisco J G Muriana, Sergio Lopez
SCOPE: Macrophage plasticity allows adapting to different environments, having a dual activity in inflammatory-related diseases. Our hypothesis is that the type of dietary fatty acids into human postprandial triglyceride-rich lipoproteins (TRLs), alone or in combination with niacin (vitamin B3), could modulate the plasticity of monocytes-macrophages. METHODS AND RESULTS: We isolated TRLs at the postprandial peak from blood samples of healthy volunteers after the ingestion of a meal rich in saturated fatty acids (SFAs), monounsaturated fatty acids (MUFAs) or MUFAs plus omega-3 long-chain polyunsaturated fatty acids (LCPUFAs)...
February 20, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28218395/coffee-tea-and-melanoma-risk-findings-from-the-european-prospective-investigation-into-cancer-and-nutrition
#8
Saverio Caini, Giovanna Masala, Calogero Saieva, Marina Kvaskoff, Isabelle Savoye, Carlotta Sacerdote, Oskar Hemmingsson, Bodil Hammer Bech, Kim Overvad, Anne Tjønneland, Kristina E N Petersen, Francesca Romana Mancini, Marie-Christine Boutron-Ruault, Iris Cervenka, Rudolf Kaaks, Tilman Kühn, Heiner Boeing, Anna Floegel, Antonia Trichopoulou, Elisavet Valanou, Maria Kritikou, Giovanna Tagliabue, Salvatore Panico, Rosario Tumino, H Bas Bueno-de-Mesquita, Petra H Peeters, Marit B Veierød, Reza Ghiasvand, Marko Lukic, José Ramón Quirós, Maria-Dolores Chirlaque, Eva Ardanaz, Elena Salamanca Fernández, Nerea Larrañaga, Raul Zamora-Ros, Lena Maria Nilsson, Ingrid Ljuslinder, Karin Jirström, Emily Sonestedt, Timothy J Key, Nick Wareham, Kay-Tee Khaw, Marc Gunter, Inge Huybrechts, Neil Murphy, Konstantinos K Tsilidis, Elisabete Weiderpass, Domenico Palli
In vitro and animal studies suggest that bioactive constituents of coffee and tea may have anticarcinogenic effects against cutaneous melanoma, however epidemiological evidence is limited to date. We examined the relationships between coffee (total, caffeinated or decaffeinated) and tea consumption and risk of melanoma in the European Prospective Investigation into Cancer and Nutrition (EPIC). EPIC is a multi-centre prospective study that enrolled over 500,000 participants aged 25-70 years from ten European countries in 1992-2000...
February 20, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28215487/executive-summary-of-management-of-prosthetic-joint-infections-clinical-practice-guidelines-by-the-spanish-society-of-infectious-diseases-and-clinical-microbiology-seimc
#9
Javier Ariza, Javier Cobo, Josu Baraia-Etxaburu, Natividad de Benito, Guillermo Bori, Javier Cabo, Pablo Corona, Jaime Esteban, Juan Pablo Horcajada, Jaime Lora-Tamayo, Oscar Murillo, Julián Palomino, Jorge Parra, Carlos Pigrau, José Luis Del Pozo, Melchor Riera, Dolores Rodríguez, Mar Sánchez-Somolinos, Alex Soriano, M Dolores Del Toro, Basilio de la Torre
The incidence of prosthetic joint infection (PJI) is expected to increase in the coming years. PJI has serious consequences for patients, and high costs for the health system. The complexity of these infections makes it necessary to organize the vast quantity of information published in the last several years. The indications for the choice of a given surgical strategy and the corresponding antimicrobial therapy are specifically reviewed. The authors selected clinically relevant questions and then reviewed the available literature in order to give recommendations according to a pre-determined level of scientific evidence...
February 16, 2017: Enfermedades Infecciosas y Microbiología Clínica
https://www.readbyqxmd.com/read/28214832/the-burden-of-respiratory-disease-in-very-low-birth-weight-infants-changes-in-perinatal-care-and-outcomes-in-a-decade-in-spain
#10
Fermín García-Muñoz Rodrigo, Antonio Losada Martínez, María Dolores Elorza Fernández, Julio Moreno Hernando, Josep Figueras Aloy, Máximo Vento Torres
BACKGROUND: Advances in perinatal care have led to a significant reduction in morbidity and mortality among very-low-birth-weight (VLBW) infants. Much of this progress is related to the prevention and management of respiratory disease. OBJECTIVES: To evaluate changes in perinatal care and its influence on respiratory morbidity and mortality among VLBW infants in Spain in 2 consecutive periods (2002-2006 and 2007-2011). METHODS: This is a retrospective analysis of data prospectively collected of all VLBW infants included in the Spanish SEN1500 network...
February 18, 2017: Neonatology
https://www.readbyqxmd.com/read/28213105/anxiolytic-and-antidepressant-like-effects-of-an-aqueous-extract-of-tanacetum-parthenium-l-schultz-bip-asteraceae-in-mice
#11
Jorge Cárdenas, Valeria Reyes-Pérez, María Dolores Hernández-Navarro, Ana María Dorantes-Barrón, Salvador Almazán, Rosa Estrada-Reyes
AIM: Tanacetum parthenium L. Schultz-Bip (Asteraceae) is widely used worldwide in traditional medicine for the treatment of convulsions and culture-bound syndromes such as susto (fear). The aim of this work was to evaluate the anxiolytic- and antidepressant-like effects of an aqueous extract of T. parthenium in behavioral paradigms in mice. The effects of T. parthenium were compared with those produced by anxiolytic and antidepressant drugs. We carried out the chemical characterization of the main constituents of T...
February 14, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28212823/cyp-epoxygenase-derived-h2o2-is-involved-in-the-endothelium-derived-hyperpolarization-edh-and-relaxation-of-intrarenal-arteries
#12
Mercedes Muñoz, Maria Elvira López-Oliva, Estéfano Pinilla, María Pilar Martínez, Ana Sánchez, Claudia Rodríguez, Albino García-Sacristán, Medardo Hernández, Luis Rivera, Dolores Prieto
Reactive oxygen species (ROS) like hydrogen peroxide (H2O2) are involved in the in endothelium-derived hyperpolarization (EDH)-type relaxant responses of coronary and mesenteric arterioles. The role of ROS in kidney vascular function has mainly been investigated in the context of harmful ROS generation associated to kidney disease. The present study was sought to investigate whether H2O2 is involved in the endothelium-dependent relaxations of intrarenal arteries as well the possible endothelial sources of ROS generation involved in these responses...
February 14, 2017: Free Radical Biology & Medicine
https://www.readbyqxmd.com/read/28211570/platelet-phagocytosis-by-granulopoietic-precursors-in-a-myelodysplastic-syndrome-overexpressing-the-p-selectin-gene
#13
Rosario M Morales-Camacho, M Dolores Serrano-Chacón, Concepción Prats-Martín, M Teresa Vargas, Ricardo Bernal, Sergio Burillo-Sanz
No abstract text is available yet for this article.
February 17, 2017: British Journal of Haematology
https://www.readbyqxmd.com/read/28210730/tuning-the-ambipolar-charge-transport-properties-of-tricyanovinyl-substituted-carbazole-based-materials
#14
Marta Reig, Gintautas Bagdziunas, Dmytro Volyniuk, Juozas V Grazulevicius, Dolores Velasco
A series of push-pull carbazole-based compounds has been experimentally and theoretically characterized in combination with the X-ray analysis of the corresponding single crystals. The introduction of the strong electron-withdrawing tricyanovinyl group in the carbazole core affords electron-transporting ability in addition to the characteristic hole-transporting properties exhibited by donor carbazole derivatives.
February 17, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28209962/characterization-of-celiac-disease-related-oat-proteins-bases-for-the-development-of-high-quality-oat-varieties-suitable-for-celiac-patients
#15
María J Giménez, Ana Real, M Dolores García-Molina, Carolina Sousa, Francisco Barro
Some studies have suggested that the immunogenicity of oats depends on the cultivar. RP-HPLC has been proposed as a useful technique to select varieties of oats with reduced immunogenicity. The aim of this study was to identify both the avenin protein patterns associated with low gluten content and the available variability for the development of new non-toxic oat cultivars. The peaks of alcohol-soluble avenins of a collection of landraces and cultivars of oats have been characterized based on the RP-HPLC elution times...
February 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28208800/help-seeking-in-suicidal-situations-paramount-and-yet-challenging-interactions-between-significant-others-of-suicidal-persons-and-health-care-providers
#16
Dolores Angela Castelli Dransart, Sophie Guerry
Significant others are often crucial for suicidal persons or suicide attempters' access to care, yet little is known about their efforts to seek help. This article presents the findings of a qualitative pilot study carried out in Switzerland on the help-seeking process of 18 significant others, their perception of the care received by their loved one, and the interactions and collaboration they experienced with professionals. Most significant others repeatedly sought out support for their loved one and themselves...
February 13, 2017: Journal of Clinical Medicine
https://www.readbyqxmd.com/read/28208227/integrating-remotely-sensed-fires-for-predicting-deforestation-for-redd
#17
Dolors Armenteras, Cerian Gibbes, Jesús A Anaya, Liliana M Dávalos
Fire is an important tool in tropical forest management, as it alters forest composition, structure, and the carbon budget. The United Nations program on Reducing Emissions from Deforestation and Forest Degradation (REDD+) aims to sustainably manage forests, as well as conserve and enhance their carbon stocks. Despite the crucial role of fire management, decision-making on REDD+ interventions fails to systematically include fires. Here, we address this critical knowledge gap in two ways. First, we review REDD+ projects and programs to assess the inclusion of fires in monitoring, reporting and verification (MRV) systems...
February 16, 2017: Ecological Applications: a Publication of the Ecological Society of America
https://www.readbyqxmd.com/read/28206729/gut-microbiota-and-gastric-disease
#18
Dolores Sgambato, Agnese Miranda, Lorenzo Romano, Marco Romano
The gut microbiota may be considered a crucial "organ" of human body because of its role in the maintenance of the balance between health as well as disease. It is mainly located in the small bowel and colon, while, the stomach was long thought to be sterile in particular for its high acid production. In particular, stomach was considered "an hostile place" for bacterial growth until the identification of Helicobacter pylori (HP). Now, the stomach and its microbiota can be considered as two different "organs" that share the same place and they have an impact on each other...
15, 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28203218/the-influence-of-working-memory-load-on-expectancy-based-strategic-processes-in-the-stroop-priming-task
#19
Juan J Ortells, Dolores Álvarez, Carmen Noguera, Encarna Carmona, Jan W de Fockert
The present study investigated whether a differential availability of cognitive control resources as a result of varying working memory (WM) load could affect the capacity for expectancy-based strategic actions. Participants performed a Stroop-priming task in which a prime word (GREEN or RED) was followed by a colored target (red vs. green) that participants had to identify. The prime was incongruent or congruent with the target color on 80 and 20% of the trials, respectively, and participants were informed about the differential proportion of congruent vs...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28202510/myc-mediates-large-oncosome-induced-fibroblast-reprogramming-in-prostate-cancer
#20
Valentina R Minciacchi, Cristiana Spinelli, Mariana Reis-Sobreiro, Lorenzo Cavallini, Sungyong You, Mandana Zandian, Xiaohong Li, Paola Chiarugi, Rosalyn M Adam, Edwin M Posadas, Giuseppe Viglietto, Michael R Freeman, Emanuele Cocucci, Neil A Bhowmick, Dolores Di Vizio
Communication between cancer cells and the tumor microenvironment results in the modulation of complex signaling networks that facilitate tumor progression. Here we describe a new mechanism of intercellular communication originating from large oncosomes (LO), which are cancer cell-derived, atypically large (1-10 μm) extracellular vesicles (EV). We demonstrate that, in the context of prostate cancer, LO harbor sustained AKT1 kinase activity, nominating them as active signaling platforms. Active AKT1 was detected in circulating EV from the plasma of metastatic prostate cancer patients and was LO specific...
February 15, 2017: Cancer Research
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