Arimatias Raitio, Susanna Heiskanen, Johanna Syvänen, Maarit K Leinonen, Teemu Kemppainen, Eliisa Löyttyniemi, Matti Ahonen, Mika Gissler, Ilkka Helenius
BACKGROUND: The spectrum of congenital vertebral defects varies from benign lesions to severe, life-threatening conditions. The etiology and maternal risk factors remain mainly unclear in isolated cases. Hence, we aimed to assess and identify potential maternal risk factors for these anomalies. Based on previous studies, we hypothesized that maternal diabetes, smoking, advanced maternal age, obesity, chronic diseases, and medication used during the first trimester of pregnancy might increase the risk of congenital vertebral malformations...
May 22, 2023: Journal of Bone and Joint Surgery. American Volume