keyword
MENU ▼
Read by QxMD icon Read
search

Plaque regression

keyword
https://www.readbyqxmd.com/read/27906841/annexin-a5-in-treated-hypertensive-patients-and-its-association-with-target-organ-damage
#1
Alessandro Maloberti, Paolo Meani, Paola Vallerio, Marisa Varrenti, Francesca Casadei, Francesco Musca, Rita Facchetti, Anna M Di Blasio, Susanna Ravassa, Giuseppe Mancia, Cristina Giannattasio
OBJECTIVE: Annexin A5 (AnxA5) has been previously linked to the presence of carotid and cardiac target organ damage (TOD) in the context of heart failure and rheumatologic patients. However, information is scant in the context of hypertension. Aim of our study was to evaluate AnxA5 in treated hypertension patients compared with normotensive controls and to determine whether it is associated with vascular and heart TOD evaluated as arterial stiffness, carotid plaque and left ventricular hypertrophy...
January 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/27899854/association-of-neutrophil-to-lymphocyte-ratio-with-the-severity-and-morphology-of-coronary-atherosclerotic-plaques-detected-by-multidetector-computerized-tomography
#2
Ahmet Hakan Ateş, Kudret Aytemir, Duygu Koçyiğit, Muhammed Ulvi Yalcin, Kadri Murat Gürses, Hikmet Yorgun, Uğur Canpolat, Tuncay Hazırolan, Necla Özer
BACKGROUND: Studies have demonstrated a consistent relationship between white blood cell (WBC) counts and coronary artery disease (CAD). The neutrophil/lymphocyte ratio (NLR) has been considered as a potential marker for identifying individuals under risk of CAD and associated events. In this study, we aimed to evaluate whether NLR was associated with the severity and morphology of coronary atherosclerotic plaques shown by multidetector computed tomography (MDCT). METHODS: Our study population consisted of 684 patients who underwent dual-source 64 slice MDCT for the assessment of CAD...
November 2016: Acta Cardiologica Sinica
https://www.readbyqxmd.com/read/27893195/photodynamic-therapy-for-the-treatment-of-atherosclerotic-plaque-lost-in-translation
#3
Manish Jain, Matthieu Zellweger, Georges Wagnières, Hubert van den Bergh, Stéphane Cook, Marie-Noelle Giraud
Acute coronary syndromeis a life-threatening condition of utmost clinical importance, which, despite recent progress in the field, is still associated with high morbidity and mortality. Acute coronary syndrome results from a rupture or erosion of vulnerable atherosclerotic plaque with secondary platelet activation and thrombus formation, which leads to partial or complete luminal obstruction of a coronary artery. During the last decade, scientific evidence demonstrated that, when an acute coronary event occurs, several non-culprit plaques are in a "vulnerable" state...
November 28, 2016: Cardiovascular Therapeutics
https://www.readbyqxmd.com/read/27886564/c-reactive-protein-is-related-to-future-cognitive-impairment-and-decline-in-elderly-individuals-with-cardiovascular-disease
#4
Galit Weinstein, Miriam Lutski, Uri Goldbourt, David Tanne
AIMS: To explore the association of C-reactive protein (CRP) plasma levels with subsequent cognitive performance and decline among elderly individuals with pre-existing cardiovascular disease (CVD), and to assess the role of cerebrovascular indices in this relationship. METHODS: CRP levels were measured in a subgroup of individuals with chronic CVD, who previously participated in a secondary prevention trial. Cognitive performance was evaluated 14.7±1.9 and 19...
November 9, 2016: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/27882428/progression-of-noncalcified-and-calcified-coronary-plaque-by-ct-angiography-in-sle
#5
Aisha Khan, Armin Arbab-Zadeh, Adnan N Kiani, Laurence S Magder, Michelle Petri
Premature coronary artery disease remains the major cause of late death in systemic lupus erythematosus (SLE). Coronary artery calcium (CAC) represents an advanced stage of atherosclerosis, whereas noncalcified coronary atherosclerotic plaque (NCP) typically is more prone to trigger acute coronary events. The aim of this study was to assess the stability of NCP over time and identify factors associated with changes in NCP in patients with SLE. CT coronary angiography and calcium scanning were performed at baseline and follow-up in thirty-six SLE patients...
November 23, 2016: Rheumatology International
https://www.readbyqxmd.com/read/27876906/topical-terbinafine-in-the-treatment-of-cutaneous-leishmaniasis-triple-blind-randomized-clinical-trial
#6
Saeedeh Farajzadeh, Amireh Heshmatkhah, Behrooz Vares, Elham Mohebbi, Azadeh Mohebbi, Mahin Aflatoonian, Sana Eybpoosh, Iraj Sharifi, Mohammad Reza Aflatoonian, Simin Shamsi Meymandi, Ali Reza Fekri, Mahshid Mostafavi
Leishmaniasis is a spectrum of disease condition with considerable health impacts, caused by different species of Leishmania. This disease is currently endemic in 98 countries and territories in the world. There are many treatment modalities for cutaneous leishmaniasis. The use of topical terbinafine in the treatment of cutaneous leishmaniasis has recently been considered. Eighty-eight participants more than two years old with proven acute CL by a positive direct smear were randomly allocated to one of the two study arms: first group received meglumine antimoniate (Glucantime) 20 mg/kg/day intramuscular injection (IM) plus a placebo ointment (Mahan Vaseline) for 20 days...
December 2016: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/27870948/hba1c-increase-is-associated-with-higher-coronary-and-peripheral-atherosclerotic-burden-in-non-diabetic-patients
#7
Roberto Scicali, Philippe Giral, Antonio Gallo, Antonino Di Pino, Agata Maria Rabuazzo, Francesco Purrello, Philippe Cluzel, Alban Redheuil, Eric Bruckert, David Rosenbaum
BACKGROUND AND AIMS: Prediabetes is associated with an increased risk of developing diabetes and cardiovascular disease. Our objective was to examine the cardiovascular (CV) risk profile of non-diabetic patients with and without prediabetes according to HbA1c, using macroangiopathic imaging biomarkers. METHODS: Our population consisted of 272 non diabetic patients aged between 40 and 70 years, with a normal fasting plasma glucose (FPG <5.6 mmol/L) and at least 1 CV risk factor...
November 4, 2016: Atherosclerosis
https://www.readbyqxmd.com/read/27867033/differences-in-a%C3%AE-brain-networks-in-alzheimer-s-disease-and-healthy-controls
#8
Huoqiang Duan, Jiehui Jiang, Jun Xu, Hucheng Zhou, Zhemin Huang, Zhihua Yu, Zhuangzhi Yan
The prevailing β-amyloid (Aβ)-cascade hypothesis is the most classical Alzheimer's disease (AD) pathogenesis. In this hypothesis, excessive Aβ plaque deposition in human brain is considered to be the cause of AD. Carbon 11-labeled Pittsburgh compound B Positron emission tomography (11C-PiB PET) is the latest technology to detect Aβ plaques in vivo. Thus, it is possible to investigate the difference of Aβ brain networks between AD patients and Health Controls (HC) by analyzing 11C-PiB PET images. In this study, a graph-theoretical method was employed to investigate the topological properties of Aβ networks in 18 Chinese AD patients and 16 HC subjects from Huashan Hospital, Shanghai...
November 17, 2016: Brain Research
https://www.readbyqxmd.com/read/27866365/periodontal-status-in-crack-and-cocaine-addicted-men-a-cross-sectional-study
#9
Patricia Ramos Cury, Maria Graças Alonso Oliveira, Jean Nunes Dos Santos
This cross-sectional study evaluated the association between crack/cocaine addiction and periodontal disease in men. Periodontal examination (probing depth, clinical attachment level, bleeding on probing, and plaque index) and interviews were performed in 160 patients (≥18 years) from the Federal University of Bahia. Crack and cocaine dependence was defined according to the medical records and interviews of each patient; all drug addicted volunteers used both crack and cocaine. T test, Chi-square test, and logistic regression were used to assess the associations between destructive periodontal disease and crack/cocaine dependence (p ≤ 0...
November 20, 2016: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/27864841/clinical-factors-predicting-the-therapeutic-response-to-ustekinumab-in-patients-with-moderate-to-severe-chronic-plaque-psoriasis
#10
Young Ji Hwang, Sang Woong Youn, Bo Ri Kim, Dae Young Yu, Youngdoe Kim, Antonio Pires, Soyun Cho, Seong Jun Seo, Eun So Lee, Joo Young Roh, Gwang Seong Choi, Min Geol Lee
While ustekinumab has been widely used as an effective biologic for the treatment of chronic plaque psoriasis, no prospective studies have specifically investigated the clinical factors that may influence treatment outcomes with ustekinumab. This post-hoc analysis aimed to identify specific clinical factors that may influence treatment outcomes with ustekinumab in psoriasis patients. In the MARCOPOLO study, 102 Korean patients with moderate to severe psoriasis were analyzed to assess the influence of baseline characteristics as clinical factors on clinical response (improvement in Psoriasis Area and Severity Index by ≥75%/90% [PASI75/PASI90]) to ustekinumab...
November 18, 2016: Journal of Dermatology
https://www.readbyqxmd.com/read/27864523/carotid-artery-web-and-ischemic-stroke-a-case-control-study
#11
Jonathan M Coutinho, Sheldon Derkatch, Alphonse R J Potvin, George Tomlinson, Leanne K Casaubon, Frank L Silver, Daniel M Mandell
OBJECTIVE: To determine whether there is an association between carotid artery web and ischemic stroke. METHODS: This was a single-center, age- and sex-matched, case-control study. Cases were consecutive patients with anterior circulation ischemic stroke of undetermined etiology (Trial of Org 10172 in Acute Stroke Treatment [TOAST] classification). Controls were consecutive patients with cerebral aneurysms, arteriovenous malformations, or primary intracerebral hemorrhages...
November 18, 2016: Neurology
https://www.readbyqxmd.com/read/27864166/perivascular-adipose-tissue-inflammation-and-coronary-artery-disease-an-autopsy-study-protocol
#12
Daniela Souza Farias-Itao, Carlos Augusto Pasqualucci, Aline Nishizawa, Luiz Fernando Ferraz Silva, Fernanda Marinho Campos, Karen Cristina Souza da Silva, Renata Elaine Paraizo Leite, Lea Tenenholz Grinberg, Renata Eloah Lucena Ferretti-Rebustini, Wilson Jacob Filho, Claudia Kimie Suemoto
BACKGROUND: Perivascular adipose tissue (PAT) inflammation may have a role in coronary artery disease (CAD) pathophysiology. However, most evidence has come from samples obtained during surgical procedures that may imply in some limitations. Moreover, the role of B lymphocytes and inflammation in PAT that is adjacent to unstable atheroma plaques has not been investigated in humans using morphometric measurements. OBJECTIVE: The objective of this study is to investigate the inflammation in PAT, subcutaneous, and perirenal adipose tissues (SAT and PrAT) among chronic CAD, acute CAD, and control groups in an autopsy study...
November 18, 2016: JMIR Research Protocols
https://www.readbyqxmd.com/read/27863350/arterial-calcification-a-new-perspective
#13
REVIEW
R Nicoll, M Henein
Arterial calcification is commonly seen in atherosclerosis, chronic kidney disease (CKD) and diabetes and has long been considered a natural progression of atherosclerosis. Yet it is a systemic condition, occurring in a wide and diverse range of disease states and no medical treatment for cardiovascular disease has yet found a way to regress it; on the contrary, lipid-lowering therapy may worsen its progression. Although numerous studies have found associations between calcification and biomarkers, none has yet found a unifying mechanism that explains the calcification found in atherosclerosis, CKD or diabetes and many of the biomarkers are equally associated with atheroma development and cardiovascular events...
November 9, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27857821/carotid-artery-atherosclerosis-in-patients-with-active-rheumatoid-arthritis-predictors-of-plaque-occurrence-and-progression-over-24-weeks
#14
Janet E Pope, Tatiana Nevskaya, Lillian Barra, Grace Parraga
INTRODUCTION: This study evaluated the prevalence and progression of subclinical carotid artery atherosclerosis in active rheumatoid arthritis (RA). METHODS: Carotid arteries of RA patients were scanned using 3D ultrasound at baseline and 24 weeks for total plaque area, vessel wall volume, and intima-media thickness (IMT), as well as arterial stiffness measured using pulse wave velocity. Variables related to inflammation, lipids and cardiovascular (CV) risk were assessed for associations with plaque progression...
2016: Open Rheumatology Journal
https://www.readbyqxmd.com/read/27856437/quantifying-intracranial-plaque-permeability-with-dynamic-contrast-enhanced-mri-a-pilot-study
#15
P Vakil, A H Elmokadem, F H Syed, C G Cantrell, F H Dehkordi, T J Carroll, S A Ansari
BACKGROUND AND PURPOSE: Intracranial atherosclerotic disease plaque hyperintensity and/or gadolinium contrast enhancement have been studied as imaging biomarkers of acutely symptomatic ischemic presentations using single static MR imaging measurements. However, the value in modeling the dynamics of intracranial plaque permeability has yet to be evaluated. The purpose of this study was to use dynamic contrast-enhanced MR imaging to quantify the contrast permeability of intracranial atherosclerotic disease plaques in symptomatic patients and to compare these parameters against existing markers of plaque volatility using black-blood MR imaging pulse sequences...
November 17, 2016: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/27856029/optical-coherence-tomography-angiography-characteristics-of-iris-melanocytic-tumors
#16
Alison H Skalet, Yan Li, Chen D Lu, Yali Jia, ByungKun Lee, Lennart Husvogt, Andreas Maier, James G Fujimoto, Charles R Thomas, David Huang
PURPOSE: To evaluate tumor vasculature with optical coherence tomography angiography (OCTA) in malignant iris melanomas and benign iris lesions. DESIGN: Cross-sectional observational clinical study. PARTICIPANTS: Patients with iris lesions and healthy volunteers. METHODS: Eyes were imaged using OCTA systems operating at 1050- and 840-nm wavelengths. Three-dimensional OCTA scans were acquired. Iris melanoma patients treated with radiation therapy were imaged again after I-125 plaque brachytherapy at 6 and 18 months...
November 14, 2016: Ophthalmology
https://www.readbyqxmd.com/read/27855752/sleep-characteristics-and-carotid-atherosclerosis-among-midlife-women
#17
Rebecca C Thurston, Yuefang Chang, Roland von Känel, Emma Barinas-Mitchell, J Richard Jennings, Martica H Hall, Nanette Santoro, Daniel J Buysse, Karen A Matthews
STUDY OBJECTIVES: Midlife, which encompasses the menopause transition in women, can be a time of disrupted sleep and accelerated atherosclerosis accumulation. Short or poor sleep quality has been associated with cardiovascular disease (CVD) risk; few studies have investigated relations among midlife women. We tested whether shorter actigraphy sleep time or poorer subjective sleep quality was associated with carotid atherosclerosis among midlife women. METHODS: 256 peri- and postmenopausal women aged 40-60 completed three days of wrist actigraphy, hot flash monitoring, questionnaires [Pittsburgh Sleep Quality Index (PSQI), Berlin], a blood draw, and carotid ultrasound [intima media thickness (IMT), plaque]...
November 14, 2016: Sleep
https://www.readbyqxmd.com/read/27852410/-relationship-between-the-risk-factors-of-coronary-artery-disease-and-degree-of-coronary-artery-plaques-assessed-by-multi-detector-row-spiral-computed-tomography
#18
Y J Sun, X Yu, S Geng, Y Zhi, H Li, T Liu, K Xu, G X Qi
Objective: To assess the association of the traditional risk factors of coronary artery disease(CAD) and degree of coronary artery plaque. Methods: A total of 3 752 patients who had a suspicion of CAD from September 2011 to November 2012 at the First Hospital of China Medical University underwent the coronary artery computed tomography. The univariable and multivariable Logistic regression were employ to assess the association the traditional risk factors of CAD and degree of coronary artery plaque. Results: Age, diabetes, hypertension and smoking were the independent risk factor for significant stenosis, multivessel lesions and high coronary artery calcium score(all P <0...
October 25, 2016: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/27851799/absence-of-association-between-cord-specific-antibody-levels-and-severe-respiratory-syncytial-virus-rsv-disease-in-early-infants-a-case-control-study-from-coastal-kenya
#19
Joyce Uchi Nyiro, Charles Jumba Sande, Martin Mutunga, Patience Kerubo Kiyuka, Patrick Kioo Munywoki, John Anthony G Scott, David James Nokes
BACKGROUND: The target group for severe respiratory syncytial virus (RSV) disease prevention is infants under 6 months of age. Vaccine boosting of antibody titres in pregnant mothers could protect these young infants from severe respiratory syncytial virus (RSV) associated disease. Quantifying protective levels of RSV-specific maternal antibody at birth would inform vaccine development. METHODS: A case control study nested in a birth cohort (2002-07) was conducted in Kilifi, Kenya; where 30 hospitalised cases of RSV-associated severe disease were matched to 60 controls...
2016: PloS One
https://www.readbyqxmd.com/read/27846344/effect-of-evolocumab-on-progression-of-coronary-disease-in-statin-treated-patients-the-glagov-randomized-clinical-trial
#20
Stephen J Nicholls, Rishi Puri, Todd Anderson, Christie M Ballantyne, Leslie Cho, John J P Kastelein, Wolfgang Koenig, Ransi Somaratne, Helina Kassahun, Jingyuan Yang, Scott M Wasserman, Robert Scott, Imre Ungi, Jakub Podolec, Antonius Oude Ophuis, Jan H Cornel, Marilyn Borgman, Danielle M Brennan, Steven E Nissen
Importance: Reducing levels of low-density lipoprotein cholesterol (LDL-C) with intensive statin therapy reduces progression of coronary atherosclerosis in proportion to achieved LDL-C levels. Proprotein convertase subtilisin kexin type 9 (PCSK9) inhibitors produce incremental LDL-C lowering in statin-treated patients; however, the effects of these drugs on coronary atherosclerosis have not been evaluated. Objective: To determine the effects of PCSK9 inhibition with evolocumab on progression of coronary atherosclerosis in statin-treated patients...
November 15, 2016: JAMA: the Journal of the American Medical Association
keyword
keyword
16460
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"