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https://www.readbyqxmd.com/read/28515369/effect-of-reverse-vessel-remodeling-on-regression-of-coronary-atherosclerosis-in-patients-treated-with-aggressive-lipid-and-blood-pressure-lowering-therapy%C3%A3-insight-from-million-study
#1
Tadatsugu Gamou, Kenji Sakata, Hayato Tada, Tetsuo Konno, Kenshi Hayashi, Hidekazu Ino, Masakazu Yamagishi, Masa-Aki Kawashiri
BACKGROUND: The MILLION study, a prospective randomized multicenter study, revealed that lipid and blood pressure (BP)-lowering therapy resulted in regression of coronary plaque as determined by intravascular ultrasound (IVUS). In the present study we performed additional analysis to investigate the associated factors with regression of coronary plaque.Methods and Results:We investigated serial 3D IVUS images from 68 patients in the MILLION study. Standard IVUS parameters were assessed at both baseline and follow-up (18-24 months)...
May 17, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/28514517/early-childhood-caries-and-psychological-perceptions-on-child-s-oral-health-increase-the-feeling-of-guilt-in-parents-an-epidemiological-survey
#2
Thiago Saads Carvalho, Jenny Abanto, Elayne Cristina Morais Pinheiro, Adrian Lussi, Marcelo Bönecker
AIM: To assess whether parents feel guilty for their children's oral problems, associating this feeling with socio-economic, demographic, and psychological factors. DESIGN: We included 1313 parent-and-child pairs in this study. The children were 2-4 years old. Parents answered questionnaires on socio-economic and demographic data, and on psychological variables. Sixteen trained dentists (κ > 0.8) examined the children for oral hygiene (the presence and absence of plaque), early childhood caries (ECC; no caries, low and high severity), malocclusion (the presence and absence), and traumatic dental injuries (TDI; the presence and absence)...
May 17, 2017: International Journal of Paediatric Dentistry
https://www.readbyqxmd.com/read/28511669/fasting-levels-of-growth-hormone-are-associated-with-carotid-intima-media-thickness-but-are-not-affected-by-fluvastatin-treatment
#3
Erik Hallengren, Peter Almgren, Maria Rosvall, Gerd Östling, Margaretha Persson, Andreas Bergmann, Joachim Struck, Gunnar Engström, Bo Hedblad, Olle Melander
BACKGROUND: Growth hormone (GH) has been linked to cardiovascular disease but the exact mechanism of this association is still unclear. We here test if the fasting levels of GH are cross-sectionally associated with carotid intima media thickness (IMT) and whether treatment with fluvastatin affects the fasting level of GH. METHODS: We examined the association between GH and IMT in 4425 individuals (aged 46-68 years) included in the baseline examination (1991-1994) of the Malmö Diet and Cancer cardiovascular cohort (MDC-CC)...
May 16, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28511475/colour-doppler-evaluation-of-extracranial-carotid-artery-in-patients-presenting-with-acute-ischemic-stroke-and-correlation-with-various-risk-factors
#4
Samrin Haq, Manoj Mathur, Jasvir Singh, Navkiran Kaur, Raminderpal Singh Sibia, Rajesh Badhan
INTRODUCTION: Stroke is defined as an abrupt onset of neurologic deficit due to vascular cause. It is one of the leading causes of mortality and morbidity all over the world making early diagnosis and treatment inevitable. Lesions of extra cranial carotid arteries are implicated in majority of cases of acute ischemic stroke. Carotid Doppler is a non-invasive imaging technique, with sensitivity approaching that of angiography. Computed Tomography (CT) plays a major role to assess the site and nature of the lesion in patients with acute ischemic stroke...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28508856/microvascular-complications-of-type-2-diabetes-mellitus-are-associated-with-plaque-score-in-the-carotid-arteries
#5
Wojciech Bartman, Katarzyna Nabrdalik, Hanna Kwiendacz, Tomasz Sawczyn, Andrzej Tomasik, Krystyna Pierzchała, Monika Adamczyk-Sowa, Agnieszka Machowska-Majchrzak, Beata Łabuz-Roszak, Władysław Grzeszczak, Janusz Gumprecht
INTRODUCTION    The "common soil" hypothesis suggests that diabetic micro- and macroangiopathy arise from a similar pathophysiological has been once proposed. It is well documented that carotid artery atherosclerosis in patients with type 2 diabetes mellitus (T2DM) is associated with cardiovascular complications; however, whether microvascular complications are similarly related remains unclear. OBJECTIVES    We aimed to explore whether plaque score or common carotid artery intima-media thickness (CIMT) is associated with the macroangiopathic or microangiopathic complications of T2DM...
May 16, 2017: Polish Archives of Internal Medicine
https://www.readbyqxmd.com/read/28506655/fiber-reinforced-composite-fixed-dental-prostheses-a-4-year-prospective-clinical-trial-evaluating-survival-quality-and-effects-on-surrounding-periodontal-tissues
#6
Diana Wolff, Theresa Wohlrab, Daniel Saure, Johannes Krisam, Cornelia Frese
STATEMENT OF PROBLEM: Although fiber-reinforced composite fixed dental prostheses (FRC FDPs) are a reliable treatment option for the restoration of single missing teeth, comparatively few prospective clinical trials (PCT) exist. PURPOSE: The purpose of this PCT was to evaluate the survival, quality outcome, and effect of FRC FDPs on periodontal health over 4 years. MATERIAL AND METHODS: Twenty-six consecutive patients (16 men, 10 women) receiving FRC FDPs with preimpregnated unidirectional fiber reinforcement were included in the trial...
May 12, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/28505975/reduced-cardiovascular-functions-in%C3%A2-patients-with-alzheimer-s-disease
#7
Wang-Sheng Jin, Xian-Le Bu, Ye-Ran Wang, Ling Li, Wei-Wei Li, Yu-Hui Liu, Chi Zhu, Xiu-Qing Yao, Yang Chen, Chang-Yue Gao, Tao Zhang, Chang-Yue Gao, Hua-Dong Zhou, Fan Zeng, Yan-Jiang Wang
Previous studies have suggested that cardiovascular functions might play a critical role in Alzheimer's disease (AD) pathogenesis. However, the relationship among heart function, blood flow of cerebral vessels, and AD remains unclear. In the present study, AD patients (n = 34) and age- and gender-matched cognitively normal controls (n = 34) were recruited. Comorbidity information was collected. The ejection fraction was measured using echocardiography, and the mean velocity, pulsatility index (PI), and resistance index (RI) of the basilar artery (BA), left terminal internal carotid artery (LTICA), and right terminal internal carotid artery (RTICA) were measured using transcranial Doppler...
May 11, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28497901/risk-factors-of-periodontal-disease-in-vietnamese-patients
#8
Thuy A V Pham, Thoai Q Kieu, Lan T Q Ngo
AIM: The aim of the present study was to assess the association of periodontitis with dental and smoking behaviors, self-perception of oral status, dental knowledge, and obesity in Vietnamese patients. METHODS: A cross-sectional study was conducted on 367 adults who first visited the Faculty of Odonto-Stomatology, University of Medicine and Pharmacy, Ho Chi Minh City, Vietnam. Information on demographic characteristics, dental and smoking behaviors, self-perception of oral status, dental knowledge, and nutritional status was investigated by a self-administered questionnaire...
May 12, 2017: Journal of Investigative and Clinical Dentistry
https://www.readbyqxmd.com/read/28495409/effect-of-asymptomatic-visible-third-molars-on-periodontal-health-of-adjacent-second-molars-a-cross-sectional-study
#9
Hong-Lei Qu, Bei-Min Tian, Kun Li, Li-Na Zhou, Zhi-Bang Li, Fa-Ming Chen
PURPOSE: Evidence that asymptomatic third molars (M3s) negatively affect their adjacent second molars (A-M2s) is limited. The present study evaluated the association between visible M3s (V-M3s) of various clinical status with the periodontal pathologic features of their A-M2s. PATIENTS AND METHODS: Subjects with at least 1 quadrant having intact first and second molars, either with V-M3s and symptom free or without adjacent V-M3s, were enrolled in the present cross-sectional investigation...
April 14, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28493931/asymptomatic-carotid-artery-stenosis-and-retinal-nerve-fiber-layer-thickness-a-community-based-observational-study
#10
Dandan Wang, Yang Li, Yong Zhou, Cheng Jin, Qi Zhao, Anxin Wang, Shouling Wu, Wen Bin Wei, Xingquan Zhao, Jost B Jonas
PURPOSE: To examine whether an abnormally thin retinal nerve fiber layer (RNFL) is associated with cerebrovascular insufficiency. DESIGN: Community-based study. METHODS: The Asymptomatic Polyvascular Abnormalities in Community Study included Chinese aged 40+ years and without histories of cerebrovascular incidents or coronary heart disease. Using transcranial Doppler and carotid duplex ultrasound examination, we assessed presence and degree of an intracranial arterial stenosis (ICAS) and extracranial carotid arterial stenosis (ECAS) and we measured the RNFL thickness by spectral-domain optical coherence tomography...
2017: PloS One
https://www.readbyqxmd.com/read/28492755/association-between-root-caries-and-depressive-symptoms-among-elders-in-carlos-barbosa-rs-brazil
#11
Otávio Pereira D'Avila, Eliana Wendland, Juliana Balbinot Hilgert, Dalva Maria Pereira Padilha, Fernando Neves Hugo
The aim of this study was to evaluate the association between depressive symptoms and root caries among independent-living older persons. All community-dwelling older adults (not hospitalized and not bedridden) living in Carlos Barbosa, RS, Brazil, were invited to participate, and 785 completed the study protocol (standardized questionnaire assessing socio-demographic information and health behavior, Geriatric Depression Scale [GDS] - brief version, and oral examination [DMFT-Root index, Visible Plaque Index and stimulated salivary flow])...
January 2017: Brazilian Dental Journal
https://www.readbyqxmd.com/read/28492188/assessment-of-maternal-risk-indicators-for-the-development-of-caries-in-their-children-a-comparative-cross-sectional-study
#12
H R Priyadarshini, Bennete Aloysius Fernandes, S S Hiremath, Avita Rath, Vanishree Shivakumar, Anand Siddappa Tegginamani
INTRODUCTION: Certain factors in mothers could be risk indicators for certain diseases in their children. Hence, this study was undertaken to assess maternal risk indicators for the development of early childhood caries in their children. METHODOLOGY: A comparative, cross-sectional study was designed among 180 mother-child pairs attending various Anganwadi centers. Demographic, dietary, oral hygiene practices and other necessary information were collected from mothers using a structured questionnaire...
April 2017: Journal of the Indian Society of Pedodontics and Preventive Dentistry
https://www.readbyqxmd.com/read/28491492/associations-between-hippocampal-morphometry-and-neuropathologic-markers-of-alzheimer-s-disease-using-7%C3%A2-t-mri
#13
Anna E Blanken, Sona Hurtz, Chris Zarow, Kristina Biado, Hedieh Honarpisheh, Johanne Somme, Jenny Brook, Spencer Tung, Emily Kraft, Darrick Lo, Denise W Ng, Harry V Vinters, Liana G Apostolova
Hippocampal atrophy, amyloid plaques, and neurofibrillary tangles are established pathologic markers of Alzheimer's disease. We analyzed the temporal lobes of 9 Alzheimer's dementia (AD) and 7 cognitively normal (NC) subjects. Brains were scanned post-mortem at 7 Tesla. We extracted hippocampal volumes and radial distances using automated segmentation techniques. Hippocampal slices were stained for amyloid beta (Aβ), tau, and cresyl violet to evaluate neuronal counts. The hippocampal subfields, CA1, CA2, CA3, CA4, and subiculum were manually traced so that the neuronal counts, Aβ, and tau burden could be obtained for each region...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28489479/biologics-and-dermatology-life-quality-index-dlqi-in-the-australasian-psoriasis-population
#14
Diana Norris, Louise Photiou, Mark Tacey, Con Dolianitis, George Varigos, Peter Foley, Chris Baker
BACKGROUND/OBJECTIVES: Psoriasis is a chronic condition that may require long-term treatment for disease control. This analysis utilises data from the Australasian Psoriasis Registry with particular attention to the impact of biologic therapy on DLQI, and the differences between the biologics in terms of DLQI score change. METHODS: A retrospective review of patients enrolled in the Australasian Psoriasis Registry from April 2008 to August 2016 was conducted. All subjects from the registry that had DLQI and Psoriasis Assessment Severity Index (PASI) scores recorded at a baseline timepoint of treatment commencement, in addition to week 12 and 24 post commencement were included in the study...
May 10, 2017: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/28488284/spontaneous-regression-of-a-plaque-type-striated-muscle-hamartoma
#15
Ximena Calderón-Castrat, Concepción Román-Curto, Angel Santos-Briz, Emilia Fernández-López, María Del Carmen Fraile Alonso
Striated muscle hamartoma (SMH) is a rare, congenital or acquired, benign tumor that predominantly affects children. Therapeutic management has classically been surgical intervention. We present a pediatric case of a facial plaque-type SMH with spontaneous regression that highlights the importance of clinical observation for a conservative approach.
May 10, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28487327/resistant-atherosclerosis-the-need-for-monitoring-of-plaque-burden
#16
J David Spence, Karla Solo
BACKGROUND AND PURPOSE: Recent studies indicate that patients with lower levels of low-density lipoprotein cholesterol (LDL-C) have greater regression of coronary plaque. In 2002, we found that carotid plaque progression doubled cardiovascular risk. In 2003, we therefore implemented a new approach, treating arteries instead of risk factors. Since then, we have seen many patients with carotid plaque progression despite very low levels of LDL-C, suggesting other causes of atherosclerosis...
May 9, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28482222/noninvasive-detection-of-increased-carotid-artery-temperature-in-patients-with-coronary-artery-disease-predicts-major-cardiovascular-events-at-one-year-results-from-a-prospective-multicenter-study
#17
Konstantinos Toutouzas, Georgios Benetos, Iosif Koutagiar, Nikolaos Barampoutis, Fotini Mitropoulou, Periklis Davlouros, Petros P Sfikakis, Dimitrios Alexopoulos, Christodoulos Stefanadis, Elias Siores, Dimitris Tousoulis
BACKGROUND AND AIMS: Limited prospective data have been reported regarding the impact of carotid inflammation on cardiovascular events in patients with coronary artery disease (CAD). Microwave radiometry (MWR) is a noninvasive, simple method that has been used for evaluation of carotid artery temperature which, when increased, predicts 'inflamed' plaques with vulnerable characteristics. We prospectively tested the hypothesis that increased carotid artery temperature predicts future cerebro- and cardiovascular events in patients with CAD...
April 23, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28480634/does-osteoporosis-influence-the-marginal-peri-implant-bone-level-in-female-patients-a-cross-sectional-study-in-a-matched-collective
#18
Florian Wagner, Krisztian Schuder, Markus Hof, Simone Heuberer, Rudolf Seemann, Gabriella Dvorak
BACKGROUND/PURPOSE: Osteoporosis, being a homeostatic imbalance, affects the remodeling of bone. Whether this catabolic bone disease influences peri-implant marginal bone remodeling remains unknown so far. The purpose of this study was to evaluate the influence of osteoporosis on peri-implant marginal bone loss (MBL) in postmenopausal women. MATERIALS AND METHODS: In a matched collective, radiographic peri-implant bone level (at baseline and at follow-up examinations) was compared in healthy and osteoporotic women...
May 8, 2017: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/28473443/relationship-of-autoantibodies-to-mda-ldl-and-apob-immune-complexes-to-sex-ethnicity-subclinical-atherosclerosis-and-cardiovascular-events
#19
Anand Prasad, Paul Clopton, Colby Ayers, Amit Khera, James A de Lemos, Joseph L Witztum, Sotirios Tsimikas
OBJECTIVE: Modifications of lipid constituents within atherosclerotic lesions generate neoepitopes that activate innate and adaptive immune responses. We aimed to define the prevalence, distribution, and relationship of autoantibody titers of oxidized lipoproteins to subclinical atherosclerosis and major adverse cardiovascular events (MACE) in different ethnic groups. APPROACH AND RESULTS: IgG and IgM autoantibodies to malondialdehyde-modified low-density lipoprotein (MDA-LDL) and apolipoprotein B-100-immune complexes were measured in 3509 individuals (1814 blacks, 1031 whites, 589 Hispanics, and 85 no race identifier) from the Dallas Heart Study with median 10...
May 4, 2017: Arteriosclerosis, Thrombosis, and Vascular Biology
https://www.readbyqxmd.com/read/28467020/the-association-of-medications-with-sedative-properties-with-oral-health-behaviour-in-community-dwelling-older-people
#20
A Tiisanoja, A-M Syrjälä, K Komulainen, S Hartikainen, H Taipale, M Knuuttila, P Ylöstalo
OBJECTIVES: The objective of this study was to determine whether drugs with sedative properties are related to oral health behaviour-such as frequency of toothbrushing, using toothpaste and dental visits-and oral hygiene, measured by the number of teeth with dental plaque, among community-dwelling older people. METHODS: The study population consisted of 159 community-dwelling, dentate, non-smoking, older people from the Oral Health GeMS study (Geriatric Multidisciplinary Strategy for the Good Care of Older People study)...
May 3, 2017: International Journal of Dental Hygiene
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