Chiayen Lin, Jiarong Li, Baiqi Liu, Xiaoyue Hong, Tao Luo, Jinsong Ye, Yi Yu, Xinran Peng, Shanmiao Gou, Huayong Tang, Tongli Yuan, Jianguan Luo, Ming Yang, Bin Feng, Zhijian Zhao, Caihong Ning, Zefang Sun, Shuai Zhu, Lu Chen, Dingcheng Shen, Gengwen Huang
BACKGROUNDS: The effectiveness of procalcitonin-based algorithms in guiding antibiotic usage for febrile acute necrotizing pancreatitis (ANP) remains controversial. Metagenomic next-generation sequencing (mNGS) has been applied to diagnose infectious diseases. We aimed to evaluate the effectiveness of blood mNGS in guiding antibiotic stewardship for febrile ANP. MATERIALS AND METHODS: The prospective multicenter clinical trial was conducted at seven hospitals in China...
February 9, 2024: International Journal of Surgery