Mingliang Li, Huapeng Li, Heqing Huang, Yanzhi Li, Li Qin, Xuan Xu, Qiang Zheng, Donghai Wang, Minghui Zhang, Yanhua Sun, Qingmin Yang
Cetrorelix, a potent third generation of luteinizing hormone releasing hormone (LHRH) antagonist, is a synthetic decapeptide used for treatment of infertility, prostatic hypertrophy and sexual hormone-dependent tumors. The approved drug of cetrorelix (Cetrotide, Asta Medica AG, Frankfurt, Germany.), was used for prevention of premature ovulation in patients undergoing a controlled ovarian stimulation (COS), followed by oocyte pick-up and assisted reproductive techniques, and has been shown safe and effective in controlled ovarian stimulation...
April 15, 2021: Journal of Pharmaceutical and Biomedical Analysis