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https://www.readbyqxmd.com/read/30315504/does-no-touch-technique-better-than-conventional-or-intermediate-saphenous-vein-harvest-techniques-for-coronary-artery-bypass-graft-surgery-a-systematic-review-and-meta-analysis
#1
Abdelrahman Elshafay, Ahmed Hesham Bendary, Huan Thanh Vuong, Ahmed Reda Ahmed, Mohamed Ashraf Mokhtar, Ali Lotfy Soliman, Nguyen Lam Vuong, Israa Atia El Bestawi, Nirmeen Atef Abdallah, Vi Tuong Vu, Kenji Hirayama, Nguyen Tien Huy
Saphenous vein (SV) is a common graft being used in coronary artery bypass grafting (CABG). Conventional (CON), intermediate (I), and no-touch (NT) are the most common harvesting techniques of SV for CABG. The aim of this study is to systematically review the NT versus CON and I techniques in harvesting SV for CABG. Twelve databases were searched for randomized controlled trials comparing the CON, I, and NT techniques in harvesting SV for CABG. Twelve reports of six RCTs were included. Our meta-analysis showed that with NT technique, patency rate was significantly higher when compared to I technique up to 18-month follow-up duration...
October 12, 2018: Journal of Cardiovascular Translational Research
https://www.readbyqxmd.com/read/30309627/meta-analysis-of-bleeding-risk-prediction-scores-in-patients-after-percutaneous-coronary-intervention-on-dual-antiplatelet-therapy
#2
Stephanie Q Ko, Linda R Valsdottir, Jordan B Strom, Yu-Chen Cheng, Atsushi Hirayama, Po-Hong Liu, Naoki Yanagisawa, Hsuan Yen, Changyu Shen, Robert W Yeh
The duration and type of dual antiplatelet therapy (DAPT) prescribed to patients after percutaneous coronary intervention (PCI) involves carefully balancing reduced ischemia and increased bleeding risk for individual patients. Whereas multiple bleeding risk scores exist, the performance of these models to predict long-term bleeding in the setting of DAPT across different settings and populations is unclear. Therefore, we performed a systematic review and meta-analysis to compare the performance of current bleeding risk prediction scores for predicting major long-term bleeding events in patients on DAPT post-PCI...
September 8, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/30305978/serious-hypokalemia-associated-with-abiraterone-acetate-in-patients-with-castration-resistant-prostate-cancer
#3
Yutaka Yamamoto, Yasunori Akashi, Takahumi Minami, Masahiro Nozawa, Keisuke Kiba, Motokiyo Yoshikawa, Akihide Hirayama, Hirotsugu Uemura
Introduction: The treatment strategy for castration-resistant prostate cancer (CRPC) has changed with the approval of several new agents. In 2011, abiraterone acetate was approved for the treatment of metastatic CRPC; however abiraterone is known to cause mineralocorticoid excess syndrome characterized by hypokalemia, fluid retention, and hypertension. We experienced two cases of grade 4 hypokalemia associated with abiraterone treatment. Case Presentation: Case 1: a 71-year-old male with metastatic CRPC presented with convulsive seizures two weeks after receiving abiraterone plus prednisone...
2018: Case Reports in Urology
https://www.readbyqxmd.com/read/30292036/hemiparesis-without-responsible-hematomas-in-patients-with-subarachnoid-hemorrhage-undergoing-early-aneurysmal-repair
#4
Takatoshi Sorimachi, Kazuma Yokota, Akihiro Hirayama, Hideaki Shigematsu, Naokazu Hayashi, Takahiro Osada, Kittipong Srivatanakul, Mitsunori Matsumae
OBJECTIVE: The presence of hemiparesis on arrival in patients with subarachnoid hemorrhage (SAH) is presumed to affect their prognosis, and intracranial hematomas with a mass effect responsible for the hemiparesis are frequently observed in these patients. The purpose of this study was to clarify the characteristics and outcomes of patients who presented with hemiparesis on arrival and showed no responsible hematomas (hemiparesis w/o hematoma) having a mass effect on computed tomography...
October 3, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/30286864/histopathologic-insights-into-the-honeycomb-like-structure-in-the-coronary-artery-in-vivo-multimodality-imaging-assessment-with-directional-coronary-atherectomy
#5
Satoshi Suzuki, Yohei Sotomi, Shimpei Nakatani, Akio Hirata, Hiroyuki Hao, Masahiko Tsujimoto, Hiromi Tsuji, Ichiro Shiojima, Yasushi Sakata, Atsushi Hirayama, Yoshiharu Higuchi
No abstract text is available yet for this article.
October 8, 2018: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/30284056/hirayama-disease-analysis-of-cases-in-russia
#6
Anna Rosliakova, Inessa Zakroyshchikova, Ilya Bakulin, Rodion Konovalov, Elena Kremneva, Marina Krotenkova, Natalya Suponeva, Mariya Zakharova
The fourteen cases of Hirayama disease (HD) are presented in this article. HD is seldom disease characterized by juvenile muscular atrophy of upper extremities and benign course. All cases were diagnosed in the Research Center of Neurology (Moscow, Russia) during the year 2015-2017. Such methods as MRI (magnetic resonance imaging), EMG (electromyography), and NCS (nerve conduction studies) have been used to confirm diagnosis of HD. Transcranial magnetic stimulation was used to exclude upper motor neuron involvement in two cases...
October 3, 2018: Neurological Sciences
https://www.readbyqxmd.com/read/30274293/a-metabolomic-based-evaluation-of-the-role-of-commensal-microbiota-throughout-the-gastrointestinal-tract-in-mice
#7
Yuri Yamamoto, Yumiko Nakanishi, Shinnosuke Murakami, Wanping Aw, Tomoya Tsukimi, Ryoko Nozu, Masami Ueno, Kyoji Hioki, Kenji Nakahigashi, Akiyoshi Hirayama, Masahiro Sugimoto, Tomoyoshi Soga, Mamoru Ito, Masaru Tomita, Shinji Fukuda
Commensal microbiota colonize the surface of our bodies. The inside of the gastrointestinal tract is one such surface that provides a habitat for them. The gastrointestinal tract is a long organ system comprising of various parts, and each part possesses various functions. It has been reported that the composition of intestinal luminal metabolites between the small and large intestine are different; however, comprehensive metabolomic and commensal microbiota profiles specific to each part of the gastrointestinal lumen remain obscure...
September 29, 2018: Microorganisms
https://www.readbyqxmd.com/read/30270072/prevalence-of-familial-hypercholesterolemia-in-patients-with-acute-coronary-syndrome-in-japan-results-of-the-explore-j-study
#8
Mariko Harada-Shiba, Junya Ako, Hidenori Arai, Atsushi Hirayama, Yoshitaka Murakami, Atsushi Nohara, Asuka Ozaki, Kiyoko Uno, Masato Nakamura
BACKGROUND AND AIMS: Prevalence of familial hypercholesterolemia (FH), a common genetic disorder with a high risk for coronary artery disease (CAD), is high among CAD patients; however, data on FH prevalence among acute coronary syndrome (ACS) patients are limited. EXPLORE-J is the largest registry to diagnose FH among Japanese ACS patients using the 2012 Japan Atherosclerosis Society guidelines. METHODS: This prospective study consecutively recruited patients between April 2015 and August 2016 at 59 sites...
October 2018: Atherosclerosis
https://www.readbyqxmd.com/read/30268412/a-new-carbapenem-drug-dosage-metric-for-carbapenem-usage-and-correlation-with-carbapenem-resistance-of-pseudomonas-aeruginosa
#9
Shinobu Hirayama, Kumiko Yasui, Hinako Murakami, Takayoshi Kosugi, Maki Sakamoto, Yuki Hanai, Kazuhiro Matsuo, Taito Miyazaki, Yoshikazu Ishii, Kenji Nishizawa, Kazuhiro Tateda
The emergence and dissemination of antimicrobial resistance is a worldwide problem. Inappropriate antimicrobial use contributes to this resistance, and several metrics of drug usage have been used to monitor their consumption and rational use. We examined several existing drug metrics, and developed a new one, dose/duration-density (D/d2 ), for a the best correlation between carbapenem usage and carbapenem resistance of Pseudomonas aeruginosa. The annual changes of antimicrobial use density (AUD), days of therapy (DOT), daily dose (DD) and D/d2 for meropenem, imipenem and total carbapenems was analyzed for a correlation with carbapenem susceptibility of P...
September 26, 2018: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/30267682/trans-omic-analysis-reveals-selective-responses-to-induced-and-basal-insulin-across-signaling-transcriptional-and-metabolic-networks
#10
Kentaro Kawata, Atsushi Hatano, Katsuyuki Yugi, Hiroyuki Kubota, Takanori Sano, Masashi Fujii, Yoko Tomizawa, Toshiya Kokaji, Kaori Y Tanaka, Shinsuke Uda, Yutaka Suzuki, Masaki Matsumoto, Keiichi I Nakayama, Kaori Saitoh, Keiko Kato, Ayano Ueno, Maki Ohishi, Akiyoshi Hirayama, Tomoyoshi Soga, Shinya Kuroda
The concentrations of insulin selectively regulate multiple cellular functions. To understand how insulin concentrations are interpreted by cells, we constructed a trans-omic network of insulin action in FAO hepatoma cells using transcriptomic data, western blotting analysis of signaling proteins, and metabolomic data. By integrating sensitivity into the trans-omic network, we identified the selective trans-omic networks stimulated by high and low doses of insulin, denoted as induced and basal insulin signals, respectively...
September 28, 2018: iScience
https://www.readbyqxmd.com/read/30264399/immunoglobulin-ig-g-antibodies-against-ige-identified-by-basophil-activation-test-as-the-putative-causative-agent-of-a-serious-allergic-transfusion-reaction-potential-utility-of-the-test-as-a-new-safety-measure-for-allergic-transfusion-reactions
#11
Kazuta Yasui, Nobuki Matsuyama, Takafumi Kimura, Yoshihiro Fujimura, Fumiya Hirayama
BACKGROUND: In most cases of allergic transfusion reactions (ATRs), the causative agents have not been identified and the mechanisms are largely unknown, with a few exceptions. The basophil activation test (BAT) was recently introduced in the field of transfusion to investigate the causal relationships between ATRs and transfusion, as well as the mechanisms behind them. STUDY DESIGN AND METHODS: The BAT was used to screen the residual supernatants (SNs) of 43 blood components associated with serious ATRs for those that can activate basophils of many healthy volunteers...
September 27, 2018: Transfusion
https://www.readbyqxmd.com/read/30252025/a-nationwide-survey-of-pediatric-onset-japanese-encephalitis-in-japan
#12
Etsuro Nanishi, Takayuki Hoshina, Masafumi Sanefuji, Ryo Kadoya, Katsuhiko Kitazawa, Yukie Arahata, Tetsuya Sato, Yoshimichi Hirayama, Katsuki Hirai, Masaaki Yanai, Kaori Nikaido, Akihiko Maeda, Hiroyuki Torisu, Kenji Okada, Yasunari Sakai, Shouichi Ohga
Background: Japanese encephalitis (JE) is the leading cause of viral encephalitis with high mortality and morbidity in Asia. In Japan, however, the active recommendation of JE vaccine was retracted in 2005 because of the potential risk of acute disseminated encephalomyelitis. We aimed to determine the recent incidence of childhood-onset JE after the domestic change of vaccination policy in Japan, and to analyze the clinical features of affected children. Methods: A retrospective nationwide survey was conducted for pediatric patients with JE in Japan from 1995 to 2015...
September 24, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/30248624/can-anterior-cervical-fusion-procedures-prevent-the-progression-of-the-natural-course-of-hirayama-disease-an-ambispective-cohort-analysis
#13
Chaojun Zheng, Cong Nie, Wei Lei, Yu Zhu, Dongqing Zhu, Hongli Wang, Feizhou Lu, Robert Weber, Jianyuan Jiang
OBJECTIVE: To clarify the effectiveness of anterior cervical fusion (ACF) in the treatment of Hirayama disease (HD). METHODS: Sixty-nine HD patients who accepted ACF procedures underwent dynamic F-waves before and soon after operation, and 36 of the 69 patients underwent pre- and postoperative magnetic resonance imaging (MRI). Motor unit number estimation, handgrip strength (HGS) and disabilities of arm, shoulder and hand (DASH) were performed in these 36 HD patients and in the other 24 patients who accepted neither neck-collar support nor operation, and these tests were reassessed about one year after initial test...
September 12, 2018: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/30232705/chronic-intestinal-pseudo-obstruction-due-to-al-amyloidosis-a-case-report-and-literature-review
#14
Tomoya Iida, Daisuke Hirayama, Gota Sudo, Kei Mitsuhashi, Hisayoshi Igarashi, Kentaro Yamashita, Hiroo Yamano, Hiroshi Nakase
A 59-year-old woman presented to our hospital with a 6-month history of nausea, weight loss, and abdominal distension. Physical examination revealed abdominal distension without tenderness, and edema, numbness, and multiple peripheral neuropathy in the limbs. Blood test results showed anemia, hypoproteinemia, and hypoalbuminemia. Immunoelectrophoresis detected kappa-type Bence-Jones protein in both the serum and urine. Bone marrow examination did not reveal an increase of plasma cells. Computed tomography showed intestinal distension and retention of intestinal contents...
September 19, 2018: Clinical Journal of Gastroenterology
https://www.readbyqxmd.com/read/30225827/correction-to-effects-of-a-combined-exercise-plus-diet-program-on-cardiorespiratory-fitness-of-breast-cancer-patients
#15
K Okumatsu, T Tsujimoto, K Wakaba, A Seki, R Kotake, T Yamauchi, S Hirayama, H Kobayashi, H Yamauchi, K Tanaka
In the original publication of this article, Table 1 was published incorrectly. The correct Table 1 is given in the following page.
September 17, 2018: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/30215439/organelle-specific-analysis-of-labile-fe-ii-during-ferroptosis-by-using-a-cocktail-of-various-colour-organelle-targeted-fluorescent-probes
#16
Tasuku Hirayama, Ayaji Miki, Hideko Nagasawa
Ferroptosis is an emerging type of cell death mode that is dependent on iron. Unfortunately, the detailed analysis of the function of organelle labile Fe(ii) in oxidative damage and lethality of the cells has not been demonstrated so far, mainly due to the lack of efficient methods to visualize labile Fe(ii) at the targeted organelles. We have recently reported a series of Fe(ii)-selective fluorescent probes, i.e., Ac-MtFluNox, Lyso-RhoNox, and ER-SiRhoNox, which can detect Fe(ii) specifically in the mitochondria, lysosomes, and endoplasmic reticulum (ER), respectively...
September 14, 2018: Metallomics: Integrated Biometal Science
https://www.readbyqxmd.com/read/30214728/efficacy-and-safety-of-sunitinib-in-elderly-patients-with-advanced-renal-cell-carcinoma
#17
Tetsuo Fujita, Takahiro Hirayama, Daisuke Ishii, Kazumasa Matsumoto, Kazunari Yoshida, Masatsugu Iwamura
Elderly individuals represent a consistent proportion of all cancer patients. However, they are under-represented in clinical trials. The present study evaluated the actual tolerability of sunitinib in elderly Japanese patients with advanced renal cell carcinoma (RCC). A total of 56 consecutive patients with advanced RCC treated with sunitinib were enrolled. Patients were divided into two groups according to their age at the time of sunitinib initiation: i) elderly cohort (≥70 years); and ii) younger cohort (<70 years)...
October 2018: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/30213538/cas9-ribonucleoprotein-complex-allows-direct-and-rapid-analysis-of-coding-and-noncoding-regions-of-target-genes-in-pleurodeles-waltl-development-and-regeneration
#18
Miyuki Suzuki, Toshinori Hayashi, Takeshi Inoue, Kiyokazu Agata, Miki Hirayama, Miyuzu Suzuki, Shuji Shigenobu, Takashi Takeuchi, Takashi Yamamoto, Ken-Ichi T Suzuki
Newts have remarkable ability to regenerate their organs and have been used in research for centuries. However, the laborious work of breeding has hampered reverse genetics strategies in newt. Here, we present simple and efficient gene knockout using Cas9 ribonucleoprotein complex (RNP) in Pleurodeles waltl, a species suitable for regenerative biology studies using reverse genetics. Most of the founders exhibited severe phenotypes against each target gene (tyrosinase, pax6, tbx5); notably, all tyrosinase Cas9 RNP-injected embryos showed complete albinism...
September 10, 2018: Developmental Biology
https://www.readbyqxmd.com/read/30211303/endoscopic-submucosal-dissection-for-early-squamous-cell-carcinoma-in-the-anal-canal-and-lugol-chromoendoscopy-for-assessment-of-the-lateral-margin
#19
Takeshi Uozumi, Tetsuya Sumiyoshi, Hitoshi Kondo, Takeyoshi Minagawa, Ryoji Fujii, Masahiro Yosida, Kaho Tokuchi, Takuya Mizukami, Koutarou Morita, Hideyuki Ihara, Yutaka Okagawa, Toshizo Takayama, Shutaro Ooiwa, Michiaki Hirayama, Yumiko Oyamada
A 66-year-old man underwent follow-up colonoscopy after colon polypectomy. The retroflexed view of the anal canal with white-light imaging revealed a whitish, slightly elevated lesion on the dentate line and an ill-defined flat lesion. A biopsy of the whitish elevation revealed squamous cell carcinoma (SCC), and endoscopic submucosal dissection (ESD) was planned. The lateral margin of the SCC was identified by spraying with Lugol's iodine, and the tumor was resected en bloc with no complications. The pathological findings were SCC in situ with parakeratosis in the whitish elevation and high-grade intraepithelial neoplasia in the ill-defined flat lesion, which exhibited a wide iodine-unstained area by chromoendoscopy...
September 2018: Endoscopy International Open
https://www.readbyqxmd.com/read/30198014/does-increased-expression-of-glucocorticoid-receptor-support-application-of-antagonists-to-this-receptor-for-the-treatment-of-castration-resistant-prostate-cancer
#20
COMMENT
Yukiyoshi Hirayama, Marianne D Sadar
No abstract text is available yet for this article.
June 2018: AME medical journal
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