keyword
https://read.qxmd.com/read/38518474/primary-extrahepatic-hydatid-cyst-of-the-thigh-an-unusual-presentation-of-sciatica-a-case-report-of-a-diagnostic-challenge
#1
Ahmed Zendeoui, Mohamed Amine Gharbi, Mouadh Nefiss, Mohamed Hedi Ezzine, Anis Tborbi, Ramzi Bouzidi
INTRODUCTION: Sciatica, a condition characterized by pain along the sciatic nerve distribution, is commonly associated with nerve compression or irritation. However, its etiology can vary, including rare non-spinal causes such as hydatid cysts. We present a case of hydatid cyst in the thigh causing sciatica-like symptoms, highlighting the diagnostic challenges and management approach. CASE PRESENTATION: A 40-year-old patient with a history of pulmonary tuberculosis presented with persistent lumbosciatic pain despite conservative treatment...
March 20, 2024: International Journal of Surgery Case Reports
https://read.qxmd.com/read/38508595/peripheral-nerve-blocks-for-through-knee-amputation-in-a-patient-on-extracorporeal-membrane-oxygenation
#2
JOURNAL ARTICLE
Nicholas Seidler, Olivia Terlep, Vendhan Ramanujam
A woman in her 40s with an ischaemic right lower limb, who was on extracorporeal membrane oxygenation (ECMO) following cardiopulmonary failure secondary to bilateral alveolar haemorrhage, was scheduled for through-knee amputation. She was under mechanical ventilation and continuous intravenous medications. Considering her significant comorbidities, peripheral nerve blocks were chosen for anaesthesia. Ultrasound-guided traditional nerve blockade techniques of the femoral and sciatic nerves were not possible because of the presence of an ECMO cannula, altered anatomy following previous surgery on the same side and inability to turn the patient to a lateral position...
March 19, 2024: BMJ Case Reports
https://read.qxmd.com/read/38508204/-not-available
#3
JOURNAL ARTICLE
Anne Carolus, Anne-Kathrin Uerschels
In regard to the complex anatomical relationship of peripheral nerves and muscles, tendons, fasciae as well as their long course within those anatomical structures and additional close contact to bony structures, they are prone to suffer from local compression syndromes. Hence creating a vast majority of entrapment syndromes - well described in literature for almost every single nerve. The purpose of this article is to give an overview of symptoms, signs, diagnostic studies and treatment options, addressing especially the less known syndromes...
February 2024: Handchirurgie, Mikrochirurgie, Plastische Chirurgie
https://read.qxmd.com/read/38496349/cauda-equina-conus-medullaris-and-syndromes-mimicking-sciatic-pain-wfns-spine-committee-recommendations
#4
REVIEW
Sandeep Vaishya, Mirza Pojskic, Manbachan Singh Bedi, Joachim Oertel, Christoph Sippl, Scott Robertson, Corinna Zygourakis
INTRODUCTION: Cauda equina syndrome (CES), conus medullaris syndrome (CMS), and sciatica-like syndromes or "sciatica mimics" (SM) may present as diagnostic and/or therapeutic dilemmas for the practicing spine surgeon. There is considerable controversy regarding the appropriate definition and diagnosis of these entities, as well as indications for and timing of surgery. Our goal is to formulate the most current, evidence-based recommendations for the definition, diagnosis, and management of CES, CMS, and SM syndromes...
April 2024: World neurosurgery: X
https://read.qxmd.com/read/38492998/the-efficacy-and-safety-of-ankle-blocks-for-foot-and-ankle-surgery-a-systematic-review-with-meta-analysis-and-trial-sequential-analysis
#5
REVIEW
Nikolaj K Schou, Lisa G T Svensson, Rasmus Cleemann, Jakob H Andersen, Ole Mathiesen, Mathias Maagaard
BACKGROUND: Peripheral nerve blocks may be essential elements in a multimodal pain management regime following foot and ankle surgery. We assessed the effects of ankle blocks compared with no intervention/sham block or a sciatic nerve block in patients undergoing surgery of the foot or ankle. METHODS: We searched CENTRAL, Medline, and Embase for randomised clinical trials comparing ankle block with no intervention/sham block or a sciatic nerve block for patients undergoing surgery of the foot or ankle...
March 7, 2024: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
https://read.qxmd.com/read/38489226/combined-dexamethasone-and-dexmedetomidine-as-adjuncts-to-popliteal-and-saphenous-nerve-blocks-in-patients-undergoing-surgery-of-the-foot-or-ankle-a-randomized-blinded-placebo-controlled-clinical-trial
#6
JOURNAL ARTICLE
Mathias Maagaard, Kamilia S Funder, Nikolaj K Schou, Jeannette Ø Penny, Peter Toquer, Jens Laigaard, Emma R Stormholt, Anders K Nørskov, Pia Jæger, Jakob H Andersen, Ole Mathiesen
BACKGROUND: Both dexamethasone and dexmedetomidine increase the duration of analgesia of peripheral nerve blocks. The authors hypothesized that combined intravenous dexamethasone and intravenous dexmedetomidine would result in a greater duration of analgesia when compared with intravenous dexamethasone alone and placebo. METHODS: The authors randomly allocated participants undergoing surgery of the foot or ankle under general anesthesia and with a combined popliteal (sciatic) and saphenous nerve block to a combination of 12 mg dexamethasone and 1 mcg/kg dexmedetomidine, 12 mg dexamethasone, or placebo (saline)...
March 14, 2024: Anesthesiology
https://read.qxmd.com/read/38486796/efficacy-of-neuroendoscopic-assisted-surgery-in-the-management-of-symptomatic-sacral-perineural-tarlov-cysts-a-technical-report
#7
JOURNAL ARTICLE
Ying Jiang, Lan Dong, Yi-Qi Pan, Jun Zhao, Wen-Fang Li, Teng-Fei Zhang, Ting Zhang, Da-Wei Dai
INTRODUCTION: The Tarlov cysts are pathological enlargements of the cerebrospinal fluid spaces between the endoneurium and perineurium, which can cause intolerable sciatic pain, motor impairment of lower limbs, and bladder/bowel dysfunction. Currently, the treatment results are unsatisfactory due to the low cure rates and extensive surgical trauma. Thus, there is an ongoing exploration of surgical techniques for Tarlov treatment. In the current study, we present a novel neuroendoscopic-assisted technique that combines the fenestration, leakage sealing, and tamponade of the Tarlov cyst...
2024: Frontiers in Surgery
https://read.qxmd.com/read/38463063/postoperative-screw-pullout-of-severe-spondylolisthesis-in-osteogenesis-imperfecta-a-case-report-with-3-year-follow-up
#8
Zhongtai Zhang, Feng Ling, Kangwu Chen, Yuxuan Liu, Qingfeng Ding, Zhigang Zhang
INTRODUCTION AND IMPORTANCE: Osteogenesis imperfecta (OI) is a rare skeletal disorder characterized by bone fragility and deformities in both paediatric and adult populations. The occurrence of severe spondylolisthesis in OI patients is even more infrequent. However, there is no consensus regarding the optimal treatment approach for OI patients afflicted with severe spondylolisthesis. The selection of surgical procedures and the effective management of postoperative complications present significant challenges in this context...
March 2024: Annals of Medicine and Surgery
https://read.qxmd.com/read/38445120/ultrasound-guided-percutaneous-cryoneurolysis-for-perioperative-analgesia-following-major-lower-extremity-amputation-a-randomized-participant-and-observer-masked-sham-controlled-pilot-study
#9
JOURNAL ARTICLE
John J Finneran, Alexandra K Schwartz, Paul J Girard, William T Kent, Omar Al-Nouri, Andrea Trescot, Brian M Ilfeld
BACKGROUND: Extremity amputations are associated with pain in both the residual limb and the phantom limb. This pain, which is often debilitating, may be prevented by excellent perioperative pain control. Ultrasound-guided percutaneous cryoneurolysis is an analgesic modality offering pain control for weeks or months following surgery. This treatment has not been compared to the sham procedure for large nerves (e.g., femoral and sciatic) to provide preoperative analgesia. We therefore conducted a randomized, controlled pilot study to evaluate the use of this modality for the treatment of pain following amputation to (1) determine the feasibility of and optimize the study protocol for a subsequent definitive clinical trial; and (2) estimate analgesia and opioid reduction within the first postoperative weeks...
February 2024: Curēus
https://read.qxmd.com/read/38428514/cannabidiol-induces-systemic-analgesia-through-activation-of-the-pi3k%C3%AE-nnos-no-katp-signaling-pathway-in-neuropathic-mice-a-katp-channel-s-nitrosylation-dependent-mechanism
#10
JOURNAL ARTICLE
Douglas Lamounier de Almeida, Renata Cristina Mendes Ferreira, Flávia Cristina Fonseca, Daniel Portela Dias Machado, Danielle Diniz Aguiar, Francisco Silveira Guimaraes, Igor Dimitri Gama Duarte, Thiago Roberto Lima Romero
BACKGROUND: Cannabidiol (CBD) is the second most abundant pharmacologically active component present in Cannabis sp. Unlike Δ-9-tetrahydrocannabinol (THC), it has no psychotomimetic effects and has recently received significant interest from the scientific community due to its potential to treat anxiety and epilepsy. CBD has excellent anti-inflammatory potential and can be used to treat some types of inflammatory and neuropathic pain. In this context, the present study aimed to evaluate the analgesic mechanism of cannabidiol administered systemically for the treatment of neuropathic pain and determine the endogenous mechanisms involved with this analgesia...
February 28, 2024: Nitric Oxide: Biology and Chemistry
https://read.qxmd.com/read/38373818/plantar-compartment-block-for-hallux-valgus-surgery-a-proof-of-concept-anatomic-and-clinical-study
#11
JOURNAL ARTICLE
Matthias Herteleer, Olivier Choquet, Fabien Swisser, Nathalie Bernard, Audrey Gasc, François Canovas, Louis Dagneaux, Sophie Bringuier, Xavier Capdevila
BACKGROUND: Hallux valgus surgery is associated with moderate to severe postoperative pain. We hypothesized that a plantar compartment block may be a good technique for postoperative analgesia. We describe an anatomic approach to ultrasound-guided plantar compartment block and assess the clinical efficacy of the block for outpatient surgery. METHODS: The anatomic study was aimed to describe the plantar compartment, using both dissection methods and imaging, and to define a volume of local anesthetic...
February 19, 2024: Regional Anesthesia and Pain Medicine
https://read.qxmd.com/read/38368171/ultrahigh-frequency-transcutaneous-electrical-nerve-stimulation-for-neuropathic-pain-alleviation-and-neuromodulation
#12
JOURNAL ARTICLE
Szu-Han Chen, Yu-Wen Lin, Wan-Ling Tseng, Wei-Tso Lin, Sheng-Che Lin, Yuan-Yu Hsueh
A challenging complication in patients with peripheral compressive neuropathy is neuropathic pain. Excessive neuroinflammation at the injury site worsens neuropathic pain and impairs function. Currently, non-invasive modulation techniques like transcutaneous electrical nerve stimulation (TENS) have shown therapeutic promise with positive results. However, the underlying regulatory molecular mechanism for pain relief remains complex and unexplored. This study aimed to validate the therapeutic effect of ultrahigh frequency (UHF)-TENS in chronic constriction injury of the rat sciatic nerve...
February 16, 2024: Neurotherapeutics: the Journal of the American Society for Experimental NeuroTherapeutics
https://read.qxmd.com/read/38340677/a-phase-3-active-controlled-trial-of-liposomal-bupivacaine-via-sciatic-nerve-block-in-the-popliteal-fossa-after-bunionectomy
#13
JOURNAL ARTICLE
Gary Schwartz, Jeffrey C Gadsden, Jeffrey Gonzales, Jacob Hutchins, Jia Song, O'Dane Brady, Mary DiGiorgi, Roy Winston
STUDY OBJECTIVE: To investigate the efficacy, safety, pharmacodynamics, and pharmacokinetics of liposomal bupivacaine (LB) administered via ultrasound-guided sciatic nerve block in the popliteal fossa in participants undergoing bunionectomy. DESIGN: Two-part, randomized, double-blind, active-controlled trial (NCT05157841). SETTING: Operating room, postanesthesia care unit, and health care facility (6 sites). PATIENTS: Adults with American Society of Anesthesiologists physical status classification ≤3 and body mass index ≥18 to <40 kg/m2 undergoing elective distal metaphyseal osteotomy...
February 9, 2024: Journal of Clinical Anesthesia
https://read.qxmd.com/read/38332999/combination-of-pericapsular-nerve-group-peng-and-sacral-erector-spinae-plane-s-esp-blocks-for-hip-fracture-pain-and-surgery-a-case-series
#14
Francesco Marrone, Pierfrancesco Fusco, Serkan Tulgar, Saverio Paventi, Marco Tomei, Fabio Fabbri, Michele Iacovazzi, Carmine Pullano
A hip fracture is a serious injury with life-threatening complications, and its risk rises with increasing age. A hip fracture can be a very painful condition, and prompt surgical treatment is recommended to reduce pain and complications. Pain management is considered integral to the management of a broken hip. The choice between general and regional anesthesia in hip fracture surgery continues to be a topic of debate because risks are potentially associated with both approaches. Nerve blockades have proven to be effective in reducing acute pain after a hip fracture and in the perioperative period...
February 2024: Curēus
https://read.qxmd.com/read/38316570/analgesic-effectiveness-of-continuous-versus-single-injection-adductor-canal-block-in-addition-to-continuous-popliteal-sciatic-nerve-block-for-bimalleolar-and-trimalleolar-ankle-fracture-surgery-prospective-randomized-controlled-trial
#15
JOURNAL ARTICLE
Young Uk Park, Han Bum Joe, Jong Wha Lee, Young Wook Seo
BACKGROUND: The adductor canal block is a well-known procedure for controlling postoperative pain after medial malleolus fracture surgery. Continuous nerve block is a viable option for blocking pain for a longer period although the literature on this subject is scarce. Therefore, this study aimed to compare continuous adductor canal block (cACB) group to single-injection adductor canal block (sACB) group in those with bimalleolar or trimalleolar ankle fractures. The procedure was performed in addition to a continuous sciatic nerve block for postoperative pain relief and patient satisfaction...
February 5, 2024: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://read.qxmd.com/read/38313966/comparative-efficacy-of-ipack-vs-popliteal-sciatic-nerve-block-for-pain-management-following-total-knee-arthroplasty-a-retrospective-analysis
#16
JOURNAL ARTICLE
Francisco Teixeira, Cristina P Sousa, Ana Patrícia Martins Pereira, Delilah Gonçalves, José C Sampaio, Miguel Sá
Introduction Total knee arthroplasty (TKA) is associated with severe acute postoperative pain. The use of tourniquets and drains (T/D) is common in TKA but may have an influence on postoperative pain and muscular strength. The infiltration of local anesthetic between the popliteal artery and capsule of the knee (iPACK block) is a motor-sparing block that provides analgesia to the posterior aspect of the knee. However, evidence regarding its efficacy is scarce. This study aims to assess the effectiveness of iPACK block and the impact of T/D use on pain and muscular strength after TKA...
January 2024: Curēus
https://read.qxmd.com/read/38285045/transient-compression-injury-triggers-neuroinflammation-in-a-new-rat-model-of-acute-peripheral-neuropathic-pain
#17
JOURNAL ARTICLE
Wenkai Wang, Xinle Huang, Yang Zhang, Junlong Wu, Yan Wang, Lanlan Li, Jianxiang Zhang, Yue Zhou
BACKGROUND: Peripheral neuropathic pain (NeP), induced by surgical intervention, is a well-known complication or sequela that remains a clinical challenge with few effective treatments. Ideal animal models that can recapitulate surgery-associated NeP remain to be established for both mechanistic studies and drug discovery. OBJECTIVES: We aimed to establish a new rat model of postsurgical NeP and describe its characteristics, as well as screen-promising therapeutic analgesics...
January 2024: Pain Physician
https://read.qxmd.com/read/38213338/distal-entrapment-of-regenerating-peripheral-nerves-after-a-proximal-injury-a-case-series-and-review-of-the-literature
#18
Alexander J Baldwin, Chane Kulenkampff, Dominic M Power
A complication of peripheral nerve injuries, of which there exists limited discourse, is the entrapment of the nerve as it regenerates from the site of injury to its end target, resulting in the arrest of axon regeneration and a consequent reduction of functional recovery. This proof-of-concept paper reports a review of the relevant literature alongside a case series of patients who presented with this phenomenon and who were treated with targeted peripheral nerve decompression. Three cases were identified prospectively...
December 2023: Curēus
https://read.qxmd.com/read/38199868/sleep-disturbance-correlated-with-severity-of-neuropathic-pain-in-sciatic-nerve-crush-injury-model
#19
JOURNAL ARTICLE
Anh Ho, Sung-Jun Lee, Victor J Drew, Jieun Jung, Jiseung Kang, Tae Kim, Chanyoung Cheong
The association between sleep and pain has been investigated widely. However, inconsistent results from animal studies compared with human data show the need for a validated animal model in the sleep-pain association field. Our study aims to validate common neuropathic pain models as a tool for evaluating the sleep-pain association. Electrodes electroencephalogram (EEG) and electromyogram (EMG) were surgically implanted to measure sleep. The von Frey test was used to measure pain sensitivity. Following the baseline data acquisition, two pain-modelling procedures were performed: sciatic nerve crush injury (SCI) and common peroneal nerve ligation (CPL)...
January 10, 2024: Journal of Sleep Research
https://read.qxmd.com/read/38171787/-investigation-of-chronic-pain-for-the-development-of-novel-analgesics-focusing-on-high-mobility-group-box-1
#20
REVIEW
Yoki Nakamura
Neuropathic pain is an infirm type of chronic pain, which results in functional and emotional impairment. There is an urgent need for novel therapeutic approaches because there is lack of effective treatment for neuropathic pain. Posttraumatic trigeminal neuropathy (PTTN), a chronic sensory disorder following trauma, for example, during dental implant surgery or third molar removal, can cause orofacial numbness, paresthesia and pain. Unlike other painful peripheral neuropathies, the chance of developing PTTN is predictable based on preoperative assessment such as X-ray of the trigeminal nerve tract and the surgery site...
2024: Yakugaku Zasshi: Journal of the Pharmaceutical Society of Japan
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