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Intraventricular tumor

Benedito Jamilson Araújo Pereira, Antônio Nogueira de Almeida, Wellingson Silva Paiva, Paulo Henrique Pires de Aguiar, Manoel Jacobsen Teixeira, Suely Kazue Nagahashi Marie
Review the data published on the subject to create a more comprehensive natural history of intraventricular meningiomas (IVMs). A Medline search up to March 2018 using "intraventricular meningioma" returned 98 papers. As a first selection step, we adopted the following inclusion criteria: series and case reports about IVMs, as well as papers written in other languages, but abstracts written in English were evaluated. Six hundred eighty-one tumors were evaluated from 98 papers. The majority of the tumors were located in the lateral ventricles (602-88...
August 15, 2018: Neurosurgical Review
Marie Kurebayashi, Akira Hashimoto, Youhei Ikenoyama, Yuichi Tahara, Hiroyuki Fuke, Atsuya Shimizu, Masahide Kondo, Hiroshi Nakano, Toshiya Kosaka
A 78-year-old woman had undergone total gastrectomy and chemotherapy for gastric cancer (pT4N3bM0 Stage IIIC, poorly differentiated adenocarcinoma). She received S-1 monotherapy 3 times weekly (S-1 at 80mg twice daily for 14 days, every 3 weeks). She underwent routine examinations, including tumor markers and computed tomography. She had no signs of recurrent disease, but she suffered from a loss of eyesight 2 years and 8 months after the operation. A choked disc was found, but she had no headaches, nausea, or unconsciousness, which indicated high intraventricular pressure...
2018: Nihon Shokakibyo Gakkai Zasshi, the Japanese Journal of Gastro-enterology
Ernest J Barthélemy, Yannis K Valtis, Maggie F Cochran, Louine Martineau, Kee Park, Jeffrey B Mendel, Benjamin Warf, Aaron L Berkowitz
INTRODUCTION: /Objective: Hydrocephalus is a common neurosurgical disorder that can lead to significant disability or death if not promptly identified and treated. Data on the burden of hydrocephalus in low-income countries is limited given lack of radiological resources for the diagnosis of this condition. Here, we present an analysis of patterns of hydrocephalus from a large sample of head CTs performed at a public hospital in rural Haiti, a low-income country in the Caribbean. METHODS: We analyzed reports from 3614 head CTs performed between July 2013 and January 2016 for findings that were consistent with a diagnosis of hydrocephalus (report indicating "hydrocephalus," "ventriculomegaly," or "enlargement of the ventricles")...
August 7, 2018: World Neurosurgery
Jawad El-Azhari, Naoufal Hjira
Tuberous sclerosis complex (TSC) is a neurocutaneous multisystemic syndrome most commonly affecting the skin, the brain, the kidneys, the lungs and the eyes. The diagnosis is based on clinical characteristics; 90% of patients have skin lesions and seizures are the initial symptom in 80% of patients. Patients with STB often show a high incidence of neuropsychiatric symptoms, including mental retardation, autism and learning difficulties. Epilepsy and brain and renal tumors are treated with aggressive therapeutic and surgical approaches...
2018: Pan African Medical Journal
Ruth Prieto, José María Pascual, Verena Hofecker, Eduard Winter, Inés Castro-Dufourny, Rodrigo Carrasco, Laura Barrios
Craniopharyngioma (CP) adherence represents a most baffling problem for the neurosurgeon. The highest priority of current surgical treatment is to maximize tumor removal without compromising the patients' long-term functional outcome. Surgical damage to the hypothalamus may be avoided or at least ameliorated with a precise knowledge regarding the type of adherence for each case. This article presents a comprehensive review of the pathological, surgical, and radiological sources of evidence supporting that CP adherence, despite being heterogenous, is characterized by repeating patterns...
July 24, 2018: Neurosurgical Review
Fabio Roberti, Martin Baggenstos
We report a rare case of an adult, with no previous history of seizures, found to have a large intraventricular Anaplastic Pleomorphic Xanthoastrocytoma (APXA). To the best of our knowledge, this is only the second documented report of an APXA located within the ventricular system in an adult. The tumor was characterized by anaplastic features and necrosis without an elevated mitotic index, and it recurred shortly after a gross total surgical resection.
May 21, 2018: Curēus
Char-Loo Tan, Daniel Landi, Herbert Fuchs, Roger E McLendon
Central neurocytoma is a rare neuronal tumor that typically occurs in young adults. Infrequently, these tumors exhibit advanced neuronal maturation and glial differentiation, giving rise to a histologically diverse tumor, in contrast to a typical central neurocytoma. We present a novel case of intraventricular central neurocytoma with prominent gangliogliomatous differentiation that developed atypical features upon recurrence after 10 years of follow up in a 10-year-old boy. Our case provides insight into the divergent differentiation capability of a neurocytic tumor and illustrates the diverse histological features of this rare entity...
July 24, 2018: Neuropathology: Official Journal of the Japanese Society of Neuropathology
Conglin Jiang, Xiang Zou, Renqing Zhu, Yimin Shi, Zehan Wu, Fan Zhao, Liang Chen
OBJECTIVE Intraventricular hemorrhage (IVH) is found in approximately 40% of intracerebral hemorrhages and is associated with increased mortality and poor functional outcome. Cognitive impairment is one of the complications and occurs due to various pathological changes. Amyloid beta (Aβ) accumulation and neuroinflammation, and the Alzheimer disease-like pathology, may contribute to cognitive impairment. Iron, the degradation product of hemoglobin, correlates with Aβ. In this study, the authors investigated the correlation between Aβ accumulation with enhanced neuroinflammation and cognitive impairment in a rat model of IVH...
July 20, 2018: Journal of Neurosurgery
Guillermo Ibáñez-Botella, Miguel Segura, Luis De Miguel, Bienvenido Ros, Miguel Ángel Arráez
Surgery for intraventricular tumors remains a controversial and evolving field, with endoscopic resection becoming more popular. We present a series of nine consecutive cases of purely endoscopic resection of intraventricular tumors with the aid of an ultrasonic aspirator specific for neuroendoscopy. Nine patients (five men, four women) aged 18-74 years (mean 43.7) underwent surgery. The most common symptom was headache. In all cases, magnetic resonance imaging showed single supratentorial intraventricular lesions (five lateral ventricle, four third ventricle)...
July 17, 2018: Neurosurgical Review
Jaime Gerardo Torres-Corzo, Mario Alberto Islas-Aguilar, Christian Daniel Cerecedo-López
BACKGROUND: Ventricular tumors represent approximately 10% of intracranial lesions and are associated with hydrocephalus in 73.9%-100% of patients. We present our experience using flexible neuroendoscopy as a diagnostic and hydrocephalus related treatment strategy for paraventricular and intraventricular tumors. METHODS: Twenty-seven pediatric and twenty-one adult patients with paraventricular or intraventricular tumors, treated with flexible neuroendoscopy were included in this retrospective cohort...
July 12, 2018: World Neurosurgery
Jamal El Ouazzani, Mustapha Beghi, Amine Kossir, Nabila Ismaili, Noha El Ouafi
Background: Cardiac intracavitary metastases from a testicular cancer are very unusual, and intra-cardiac metastasis is exceptionally the first expression of a noncardiac primary neoplasm. We report a case of a young patient for whom a cardiac symptom led to the diagnosis of a metastatic testicular cancer. Case presentation: Our presentation describes an unusual case of a 32 years-old male patient admitted for dyspnea, in whom full examination and tests led to the diagnosis of a huge right ventricular mass revealing a testicular malignant teratoma...
July 2018: Journal of the Saudi Heart Association
Hitoshi Kayatani, Naoki Nitta, Suzuko Moritani, Kazuhiko Nozaki
Background: Primary lymphomas in the choroid plexus are much less frequent than primary lymphomas in the brain parenchyma. Case Description: A 66-year-old male patient was referred to our department with a right intraventricular mass that had been diagnosed by biopsy at another hospital as anaplastic ependymoma. The patient underwent subtotal removal of the tumor via a transcortical inferior temporal gyrus approach. The mass was attached to the choroid plexus in the right atrium...
2018: Surgical Neurology International
R Kouitcheu, A Melot, M Diallo, L Troude, R Appay
We report here a case of intraventricular schwannoma. This location is rare. Our patient was a 68-year-old female with a large intraventricular lesion of the body of the lateral ventricle on the right side. Brain magnetic resonance imaging (MRI) revealed this lesion. After a right parietotemporal craniotomy, microsurgical excision using neuronavigation was performed to completely remove the tumor. Histological and immunohistochemical examination confirmed the diagnosis of intraventricular schwannoma devoid of atypical features...
June 12, 2018: Neuro-Chirurgie
Coriene Catsman-Berrevoets, Zoltan Patay
Cerebellar mutism most commonly, but not exclusively, develops in children after surgery for midline cerebellar or intraventricular tumors in the posterior fossa, typically medulloblastoma. Cerebellar mutism syndrome (CMS) comprises a complex set of neurologic and neurocognitive signs and symptoms, the cardinal and central component of which is an initially profound but usually reversible speech disorder. As such, CMS is currently recognized as an extreme form of the so-called cerebellar cognitive affective syndrome (Schmahmann syndrome)...
2018: Handbook of Clinical Neurology
Juan C Fernandez-Miranda
The medial temporal lobe can be divided in anterior, middle, and posterior segments. The anterior segment is formed by the uncus and hippocampal head, and it has extra and intraventricular structures. There are 2 main approaches to the uncohippocampal region, the anteromedial temporal lobectomy (Spencer's technique) and the transsylvian selective amygdalohippocampectomy (Yasargil's technique).In this video, we present the case of a 29-yr-old man with new onset of generalized seizures and a contrast-enhancing lesion in the left anterior segment of the medial temporal lobe compatible with high-grade glioma...
June 7, 2018: Operative Neurosurgery (Hagerstown, Md.)
Leomar Y Ballester, Isabella C Glitza Oliva, Dzifa Y Douse, Melissa M Chen, Chieh Lan, Lauren E Haydu, Jason T Huse, Sinchita Roy-Chowdhuri, Rajyalakshmi Luthra, Ignacio I Wistuba, Michael A Davies
Circulating tumor DNA (ctDNA) refers to tumor-derived cell-free DNA that circulates in body fluids. Fluid samples are easier to collect than tumor tissue, and are amenable to serial collection at multiple time points during the course of a patient's illness. Studies have demonstrated the feasibility of performing mutation profiling from blood samples in cancer patients. However, detection of ctDNA in the blood of patients with brain tumors is suboptimal. Cerebrospinal fluid (CSF) can be obtained via lumbar puncture or intraventricular catheter, and may be a suitable fluid to assess ctDNA in patients with brain tumors...
July 1, 2018: Journal of Neuropathology and Experimental Neurology
Takuhiro Shoji, Tomohiro Kawaguchi, Yoshikazu Ogawa, Mika Watanabe, Miki Fujimura, Teiji Tominaga
Nonobstructive hydrocephalus in patients with craniopharyngiomas is uncommon. We describe our surgical series of 25 consecutive patients with craniopharyngioma who presented with hydrocephalus. Obstructive hydrocephalus was evident in most cases, and nonobstructive hydrocephalus was revealed in three cases. Even after improvement of cerebrospinal fluid (CSF) pathway obstruction by tumor removal, 10 patients (40%) required CSF diversion. Preoperative imaging study revealed thin intraventricular hemorrhage or superficial siderosis in five cases, and CSF examination revealed hemosiderin-laden phagocytes in one case...
June 5, 2018: Journal of Neurological Surgery. Part A, Central European Neurosurgery
Alexandre Iscaife, Sabrina Thalita Reis, Denis Reis Morais, Nayara Izabel Viana, Iran Amorim da Silva, Ruan Pimenta, Andre Bordini, Nelson Dip, Miguel Srougi, Katia Ramos Moreira Leite
Prostate cancer (PCa) is an incurable disease at the metastatic stage. Although there are different options for treatment, the results are limited. MicroRNAs (miRNAs) are a group of small, noncoding, regulatory RNAs with important roles in regulating gene expression. miR-145 is reported to be a key tumor suppressor miRNA (tsmiR) that controls important oncogenes, such as MYC and RAS. In this study, in vitro studies were performed to show the control of MYC and RAS by miR-145. Flow cytometry was used to analyze cell proliferation and apoptosis...
August 2018: Apoptosis: An International Journal on Programmed Cell Death
Mahmoud Abbassy, Khaled Aref, Ahmed Farhoud, Anwar Hekal
BACKGROUND: Tumors within the pineal region represent 1.5 to 8.5% of the pediatric brain tumors and 1.2% of all brain tumors. A management algorithm has been proposed in several publications. The algorithm includes endoscopic third ventriculostomy (ETV) and biopsy in cases presenting with hydrocephalus. In this series, we are presenting the efficacy of a single-trajectory approach for both ETV and biopsy. METHODS: Eleven cases were admitted to Alexandria main university hospital from 2013 to 2016 presenting with pineal region tumors and hydrocephalus...
July 2018: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
Alexander Verhaeghe, Stijn De Muynck, Jan W Casselman, Nikolaas Vantomme
BACKGROUND: Pneumocephalus is usually seen in trauma or cranial surgery. It is rarely reported as a delayed complication of ventriculoperitoneal shunt placement for hydrocephalus secondary to trauma, tumor, or aqueduct stenosis. We describe a case of intraventricular pneumocephalus manifesting 10 months after placement of a shunt for normal-pressure hydrocephalus. CASE DESCRIPTION: A pressure-regulated ventriculoperitoneal shunt was implanted in an 81-year-old patient after diagnosis of normal-pressure hydrocephalus...
August 2018: World Neurosurgery
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