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Oral AND health

Jianbo Li, Weihua Fan, Yu Lu, Dongying Xuan, Ziqiang Liu, Shaohong Huang, Jincai Zhang
BACKGROUND: Erosive tooth wear (ETW) has become a crucial oral health problem over the decades in China. OBJECTIVES: To explore the prevalence and risk indicators of ETW among adolescents in Guangzhou, south China. METHODS: A cross-sectional survey of 720 participants was conducted in Guangzhou, using an equal-sized, stratified, multistage random sampling approach. The participants were from two different age groups(12- and 15-year-olds), 360 per group...
December 16, 2018: Journal of Oral Rehabilitation
Peter H Kook, Martin Hersberger
BACKGROUND: Efficacy of PO cobalamin (Cbl) supplementation in dogs with hereditary Cbl malabsorption (Imerslund-Gräsbeck syndrome, IGS) is unknown. OBJECTIVES: To evaluate PO Cbl supplementation in Beagles with IGS previously treated parenterally. We hypothesized that 1 mg cyano-Cbl daily PO would maintain clinical and metabolic remission. ANIMALS: Three client-owned Beagles with IGS and 48 healthy control dogs. METHODS: Prospective study...
December 15, 2018: Journal of Veterinary Internal Medicine
Song-Zi Xie, Bing Liu, Hui-Yu Ye, Qiang-Ming Li, Li-Hua Pan, Xue-Qiang Zha, Jian Liu, Jun Duan, Jian-Ping Luo
The present study investigated the effects of a homogeneous Dendrobium huoshanense polysaccharide (GXG) on mucosal barrier function and microbiota composition in different intestinal regions of mice. Results exhibited, besides changing the intestinal physiological status, orally administrated GXG could improve the intestinal physical barrier function by modulating mucosal structures and up-regulating the expression of tight junction proteins, reinforce the intestinal biochemical barrier function by elevating the expression and secretion of mucin-2, β-defensins and sIgA, and regulate the intestinal immunological barrier function by stimulating the production of cytokines and the functional development of immune cells...
February 15, 2019: Carbohydrate Polymers
G Gatt, N Attard
AIM: To determine the influence of erosive tooth wear in the primary dentition on parental perceptions of oral health. METHODS: This cross-sectional study involved a standardised clinical examination of 775 preschool aged children and a parent-administered questionnaire. Erosive tooth wear was measured using the Basic Erosive Wear Examination Index. RESULTS: 71% and 81% of 3 (n = 256) and 5 year-old children (n = 337) respectively exhibited signs of erosive tooth wear...
December 14, 2018: European Archives of Paediatric Dentistry: Official Journal of the European Academy of Paediatric Dentistry
Craig S Miller, Douglas E Peterson
There have been strategic clinical, educational, and research advances in the field of Oral Medicine over the past several decades. In many cases, Oral Medicine experts are contributing the lead role in these advances nationally and internationally. In addition, American Board of Dental Specialty recognition of Oral Medicine as a specialty in 2015 has positioned Oral Medicine professionals to substantively enhance the delivery of oral health care to medically complex patients as well. It is now important and timely to capitalize on this contemporary foundation, to advance the field of Oral Medicine in the United States for the next generation of Oral Medicine specialists and practitioners...
November 2018: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
Amanda E Janitz, Hanh Dung Dao, Janis E Campbell, Julie A Stoner, Jennifer D Peck
BACKGROUND: Natural gas drilling may pose multiple health risks, including congenital anomalies, through air pollutant emissions and contaminated water. Two recent studies have evaluated the relationship between natural gas activity and congenital anomalies, with both observing a positive relationship. OBJECTIVES: We aimed to evaluate whether residence near natural gas wells is associated with critical congenital heart defects (CCHD), neural tube defects (NTD), and oral clefts in Oklahoma, the third highest natural gas producing state in the US...
December 11, 2018: Environment International
Caijuan Zhang, Baosheng Zhao, Chi Zhang, Minyi Qiu, Shuangshuang Ma, Xiaoyan Jin, Yuanyang Shao, Min Wang, Xueyong Wang
With increasing air pollution, chronic bronchitis (CB) has become a major public health problem worldwide. Previous studies have shown beneficial effects of Bergenin (Ber) on chronic bronchitis. To facilitate understanding of the pathogenesis underlying CB as well as to elucidate the Ber therapeutic mechanism, it is crucial to confirm the rational biomarkers of CB and its treatment. This study aimed to investigate the preventive chronic bronchitis mechanism of Ber by applying a serum metabolomics strategy. In this study, 18 Sprague-Dawley rats were randomly divided into three groups,with six rats in each group...
January 2019: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
Marcie S Rubin, Natali Nunez, Jessica D Quick, Burton L Edelstein
OBJECTIVES: To identify and characterize US early childhood caries (ECC) programs. METHODS: A 39 question online survey was fielded to 245 ECC programs identified from the literature and peer programs. The 101 respondents (41 percent response rate) reported their program's geographic reach, type, areas of focus, target populations, approaches, affiliations, providers, goals, costs, and funding. RESULTS: Half of the programs affiliate with formal early childhood social service or nutrition programs...
December 14, 2018: Journal of Public Health Dentistry
Surani Fernando, Santhosh Kumar, Mahmoud Bakr, David Speicher, Rodney Lea, Paul A Scuffham, Newell W Johnson
OBJECTIVES: This study explored the association of children's salivary characteristics, past caries experience, birth weight, and reported maternal prenatal vitamin and mineral supplementation with the dental untreated decay of the child. METHODS: This cross-sectional study, a sub-study of Griffith University Environments for Healthy Living birth cohort study, was conducted on 174 mother-child dyads. Mother's prenatal usage of vitamin and mineral supplements; child's birthweight; salivary pH, buffering capacity, and levels of salivary MS and LB were explored as risk indicators...
December 14, 2018: Journal of Public Health Dentistry
Paolo Vercellini, Paola Viganò, Giussy Barbara, Laura Buggio, Edgardo Somigliana
Elagolix, an orally active non-peptidic GnRH antagonist, has been approved by the Food and Drug Administration for the management of moderate to severe pain associated with endometriosis. As the degree of ovarian suppression obtained with elagolix is dose-dependent, pain relief may be achieved by modulating the level of hypo-oestrogenism while limiting side effects. Elagolix may thus be considered a novelty in terms of its endocrine and pharmacological properties but not for its impact on the pathogenic mechanisms of endometriosis, as the target of this new drug is, yet again, alteration of the hormonal milieu...
December 14, 2018: Human Reproduction
Saeed Bashirian, Shabnam Seyedzadeh-Sabounchi, Samane Shirahmadi, Ali-Reza Soltanian, Akram Karimi-Shahanjarini, Farshid Vahdatinia
OBJECTIVE: Gingivitis and poor oral hygiene status are the most prevalent oral diseases among primary school students. Poor oral hygiene status, gingivitis and socio-demographic determinants have been shown to be associated with periodontal diseases. There is limited information on the gingivitis and oral hygiene status among Iranian children. In the present study, the status of gingivitis, oral hygiene status, and their association with socio-demographic determinants among schoolchildren aged 7-12 years old in Hamadan were investigated...
2018: PloS One
Davide Ballabio, Francesca Grisoni, Viviana Consonni, Roberto Todeschini
The ICCVAM Acute Toxicity Workgroup (U.S. Department of Health and Human Services), in collaboration with the U.S. Environmental Protection Agency (U.S. EPA, National Center for Computational Toxicology), coordinated the "Predictive Models for Acute Oral Systemic Toxicity" collaborative project to develop in silico models to predict acute oral systemic toxicity for filling regulatory needs. In this framework, new Quantitative Structure-Activity Relationship (QSAR) models for the prediction of very toxic (LD50 lower than 50 mg/kg) and nontoxic (LD50 greater than or equal to 2,000 mg/kg) endpoints were developed, as described in this study...
December 14, 2018: Molecular Informatics
Michael I MacEntee, Sabrina T Wong, Iris Chi, Edward C M Lo, Victor Minichiello, Shimae Soheilipour, Rodrigo Mariño
AIMS: The aim of this study was to explain through the life-course and life-span perspectives of developmental regulation theory the controls on dental experiences and beliefs throughout the lives of older people in Guangzhou and Hong Kong. BACKGROUND: Dental diseases and disabilities among older people are serious public health concerns in China. METHODS: A facilitator conducted eight focus groups, three in Hong Kong and five in Guangzhou, involving a total of 51 participants...
December 14, 2018: Gerodontology
Rami Kankaanpää, Juha Auvinen, Kari Rantavuori, Jari Jokelainen, Jaro Karppinen, Satu Lahti
INTRODUCTION: Dental fear is a prevalent problem leading to severe deterioration of oral health and health-related quality of life. Despite the knowledge that dental fear is closely linked to painful experience, the association between pain sensitivity and dental fear remains unclear. This study was designed to evaluate this association with validated measures of dental fear and pressure pain sensitivity in a cohort population. METHODS: The study population consisted of a subpopulation of the Northern Finland Birth Cohort 1966...
December 13, 2018: Community Dentistry and Oral Epidemiology
Yun Shen, Junhong Leng, Weiqin Li, Shuang Zhang, Huikun Liu, Ping Shao, Peng Wang, Leishen Wang, Huiguang Tian, Cuilin Zhang, Xilin Yang, Zhijie Yu, Lifang Hou, Jaakko Tuomilehto, Gang Hu
OBJECTIVE: To investigate the association of lactation intensity and duration with postpartum diabetes and prediabetes risks among Chinese women with a history of GDM. METHODS: We included 1260 women with a history of GDM who participated in the whole populationꞋs GDM universal screening survey by using World Health OrganizationꞋs criteria. Lactation intensity and lactation duration were collected by a standardized questionnaire. Postpartum diabetes and prediabetes were confirmed by an oral glucose tolerance test...
December 13, 2018: Diabetes/metabolism Research and Reviews
Herry Novrinda, Dong-Hun Han, Kyunghee Jung-Choi, Jae-In Ryu
AIM: The aims of this study were to examine inequalities in periodontitis and tooth loss among South Korean adults using the Wright's Neo-Marxian social class (NMSC) indicator and to assess the impact of material, psychosocial, health behavioural and workplace environmental factors in the association of social class with oral health. METHODS: This study used the data from the 4th Korea National Health and Nutrition Examination Survey with 6710 participants aged 19-54 years old...
December 13, 2018: Community Dentistry and Oral Epidemiology
Toby C Trujillo, Paul P Dobesh, George H Crossley, Shannon W Finks
INTRODUCTION: As overall prevalence of atrial fibrillation (AF) continues to rise, the number of patients who undergo ablation, or electrical/chemical cardioversion, to restore normal sinus rhythm continues to increase as well. As direct oral anticoagulants (DOACs) have continued to be incorporated into clinical practice for long-term anticoagulation for AF, experience with how best to manage use of DOACs during electrophysiologic procedures is evolving. OBJECTIVE: This review is intended to provide health care providers with a summary of current evidence regarding the use of DOACs during cardioversion and catheter ablation and provide key considerations for their use during such electrophysiologic procedures...
December 12, 2018: Pharmacotherapy
Ivana Petrovic, Hina Panchal, Paula Demetrio De Souza Franca, Marisol Hernandez, Colleen C McCarthy, Jatin P Shah
BACKGROUND: Segmental mandibulectomy impairs health-related quality of life (QoL), by altering speech, mastication, swallowing, and facial aesthetics. Fibula free flap (FFF) used for mandible reconstruction is known to improve outcomes; however, minimal information exists in the literature regarding patient-reported outcomes. We aim to assess how current studies evaluate patient perception following segmental mandibulectomy and FFF mandible reconstruction. METHODS: Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, a search was conducted for publications involving FFF mandible reconstruction from 2005 to 2017 using PubMed, Cochrane, EMBASE, Web of Science, and PsychInfo...
December 12, 2018: Head & Neck
Samiah Al-Zaidy, A Simon Pickard, Kavitha Kotha, Lindsay N Alfano, Linda Lowes, Grace Paul, Kathleen Church, Kelly Lehman, Douglas M Sproule, Omar Dabbous, Benit Maru, Katherine Berry, W David Arnold, John T Kissel, Jerry R Mendell, Richard Shell
BACKGROUND: Spinal Muscular Atrophy type 1 (SMA1) is a rare genetic neuromuscular disease where 75% of SMA1 patients die/require permanent-ventilation by 13.6 months. This study assessed the health outcomes of SMA1 infants treated with AVXS-101 gene replacement therapy. METHODS: Twelve genetically confirmed SMA1 infants with homozygous deletions of the SMN1 gene and two SMN2 gene copies received a one-time intravenous proposed therapeutic dose of AVXS-101 in an open label study conducted between December 2014 and 2017...
December 12, 2018: Pediatric Pulmonology
Fu-Min Fang, Tai-Lin Huang, Yun-Hsuan Lin, Chih-Yen Chien, Hui-Ching Chuang, Sheng-Dean Luo, Hsin-Ching Lin, Yu-Tsai Lin, Shau-Hsuan Li, Kuan-Cho Liao, Wen-Ling Tsai
BACKGROUND: To investigate the toxicity, changes of quality of life (QOL), and survival for patients with nasopharyngeal cancer (NPC) treated by concurrent chemoradiotherapy (CCRT) with simultaneously integrated boost volumetric-modulated arc therapy (SIB-VMAT). METHODS: A total of 68 NPC patients treated by CCRT with SIB-VMAT technique were collected. QOL was longitudinally assessed by the EORTC QLQ-C30 and HN35 questionnaires at the 4 time points: baseline, 42...
December 10, 2018: Head & Neck
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