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https://www.readbyqxmd.com/read/30294857/assessment-of-plasma-lactate-and-core-peripheral-temperature-gradient-in-association-with-stages-of-naturally-occurring-myxomatous-mitral-valve-disease-in-dogs
#1
Felipe B Soares, Gláucia B Pereira-Neto, Rodrigo C Rabelo
OBJECTIVE: To evaluate plasma lactate concentrations and core-peripheral temperature gradients as perfusion parameters in dogs with heart failure caused by myxomatous mitral valve disease (MMVD) and to determine whether the above perfusion parameters are correlated with disease stages. DESIGN: Prospective observational study. SETTING: University teaching hospital. ANIMALS: After excluding 129 dogs because of exclusion criteria, 7 dogs with heart failure classified as stage B2 and 10 dogs classified as stage C according to the American Heart Association (AHA)/American College of Cardiology (ACC) were included in the study...
October 7, 2018: Journal of Veterinary Emergency and Critical Care
https://www.readbyqxmd.com/read/30257798/prosthesis-patient-mismatch-in-62-125-patients-following-transcatheter-aortic-valve-replacement-from-the-sts-acc-tvt-registry
#2
Howard C Herrmann, Samuel A Daneshvar, Gregg C Fonarow, Amanda Stebbins, Sreekanth Vemulapalli, Nimesh D Desai, David J Malenka, Vinod H Thourani, Jennifer Rymer, Andrzej S Kosinski
BACKGROUND: Prosthesis-patient mismatch (PPM) after surgical aortic valve replacement (AVR) for aortic stenosis is generally associated with worse outcomes. Transcatheter AVR (TAVR) can achieve a larger valve orifice and the effects of PPM after TAVR are less well studied. OBJECTIVES: The authors utilized the Society of Thoracic Surgeons/American College of Cardiology TVT (Transcatheter Valve Therapy) registry to examine the frequency, predictors, and association with outcomes of PPM after TAVR in 62,125 patients enrolled between 2014 and 2017...
September 18, 2018: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/30052224/refractory-hypokalemia-while-weaning-off-bypass
#3
Rashmi Soori, Aanchal Dixit, Prabhat Tewari
Hypokalemia is defined as serum potassium level less than 3.5 mEq/L. When the serum level of potassium is less than 3 mEq/L, intravenous potassium supplementation is warranted. A 23 yr old adult female with complaints of dyspnoea (NYHA II) since 6 yrs, dyspnoea (NYHA III) and paroxysmal nocturnal dyspnoea on and off since 2 months, diagnosed with severe mitral stenosis, was posted for mitral valve replacement. After the release of ACC, ECG revealed sine wave pattern, Transesophageal echocardiographic examination revealed global hypokinesia and ABG showed potassium of 2...
July 2018: Annals of Cardiac Anaesthesia
https://www.readbyqxmd.com/read/29233358/prosthetic-valve-on-valve-mitral-valve-re-replacement-a-novel-approach
#4
Sarin Mathew, Melissa Bouchard, J Andreas Hoschtitzky
Repeat mitral valve replacement in patients who underwent mechanical replacement during infancy may be technically very difficult due to the small-sized annulus accommodating the prosthesis. That can lead to dense fibrosis of the small annulus onto the sewing cuff. An attempt at explanting the prosthesis carries high risk of circumflex coronary artery injury or atrioventricular junction disruption. We present a novel approach to prevent a disaster in such a difficult scenario-implanting the new prosthesis above the previous prosthetic housing after removing the prosthetic leaflets...
January 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29168146/novel-direct-annuloplasty-fastener-system-for-minimally-invasive-mitral-valve-repair
#5
Joshua L Chan, Ming Li, Dumitru Mazilu, Justin G Miller, Andrada C Diaconescu, Keith A Horvath
The development of less invasive approaches for mitral valve repair remains an important objective, particularly in patients with multiple comorbidities. We describe a novel method to affix a mitral valve annuloplasty ring in a minimally invasive manner. A delivery apparatus for an annuloplasty fastener system was designed. Two channels were created, one for advancing the annuloplasty ring, and another to accommodate the fastener applicator. Custom designed fasteners, either with a helical-shaped screw or a strap-shaped tack structure, were tested...
March 2018: Cardiovascular Engineering and Technology
https://www.readbyqxmd.com/read/29096801/outcomes-with-transcatheter-mitral-valve-repair-in-the-united-states-an-sts-acc-tvt-registry-report
#6
Paul Sorajja, Sreekanth Vemulapalli, Ted Feldman, Michael Mack, David R Holmes, Amanda Stebbins, Saibal Kar, Vinod Thourani, Gorav Ailawadi
BACKGROUND: Post-market surveillance is needed to evaluate the real-world clinical effectiveness and safety of U.S. Food and Drug Administration-approved devices. OBJECTIVES: The authors examined the commercial experience with transcatheter mitral valve repair for the treatment of mitral regurgitation. METHODS: Data from the Society of Thoracic Surgery/American College of Cardiology Transcatheter Valve Therapy Registry on patients commercially treated with transcatheter mitral valve repair were analyzed...
November 7, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29055505/2017-acc-expert-consensus-decision-pathway-on-the-management-of-mitral-regurgitation-a-report-of-the-american-college-of-cardiology-task-force-on-expert-consensus-decision-pathways
#7
REVIEW
Patrick T O'Gara, Paul A Grayburn, Vinay Badhwar, Luis C Afonso, John D Carroll, Sammy Elmariah, Aaron P Kithcart, Rick A Nishimura, Thomas J Ryan, Allan Schwartz, Lynne Warner Stevenson
Mitral regurgitation (MR) is a complex valve lesion that can pose significant management challenges for the cardiovascular clinician. This Expert Consensus Document emphasizes that recognition of MR should prompt an assessment of its etiology, mechanism, and severity, as well as indications for treatment. A structured approach to evaluation based on clinical findings, precise echocardiographic imaging, and when necessary, adjunctive testing, can help clarify decision making. Treatment goals include timely intervention by an experienced heart team to prevent left ventricular dysfunction, heart failure, reduced quality of life, and premature death...
November 7, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/28636718/trends-and-outcomes-of-off-label-use-of-transcatheter-aortic-valve-replacement-insights-from-the-ncdr-sts-acc-tvt-registry
#8
Ravi S Hira, Sreekanth Vemulapalli, Zhuokai Li, James M McCabe, John S Rumsfeld, Samir R Kapadia, Mahboob Alam, Hani Jneid, Creighton Don, Mark Reisman, Salim S Virani, Neal S Kleiman
Importance: Transcatheter aortic valve replacement (TAVR) was approved by the US Food and Drug Administration for severe aortic stenosis in patients who cannot undergo surgery and for patients at high operative risk. Use of TAVR for off-label indications has not been previously reported. Objective: To evaluate patterns and adverse outcomes of off-label use of TAVR in US clinical practice. Design, Setting and Participants: Patients receiving commercially funded TAVR in the United States are included in the Transcatheter Valve Therapy Registry...
August 1, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/28614262/minimally-invasive-mitral-valve-replacement-is-a-safe-and-effective-surgery-for-patients-with-rheumatic-valve-disease-a-retrospective-study
#9
Junyu Zhai, Lai Wei, Ben Huang, Chunsheng Wang, Hongqiang Zhang, Kanhua Yin
The aim of the study was to evaluate the treatment of minimally invasive mitral valve replacement (MIMVR) through a right minithoracotomy for patients with rheumatic mitral valve disease.From February 2009 to December 2016, 360 patients with rheumatic mitral valve disease underwent mitral valve replacement by the same surgeon. Among them, 150 patients accepted MIMVR through a right minithoracotomy, whereas the other 210 accepted a traditional median sternotomy. After matching by patients by age, sex, EuroSCORE, New York Heart Association (NYHA) classification, renal and liver function, and degree of mitral valve disease, we selected 224 patients for analysis in our retrospective study...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27956264/2016-annual-report-of-the-society-of-thoracic-surgeons-american-college-of-cardiology-transcatheter-valve-therapy-registry
#10
MULTICENTER STUDY
Frederick L Grover, Sreekanth Vemulapalli, John D Carroll, Fred H Edwards, Michael J Mack, Vinod H Thourani, Ralph G Brindis, David M Shahian, Carlos E Ruiz, Jeffrey P Jacobs, George Hanzel, Joseph E Bavaria, E Murat Tuzcu, Eric D Peterson, Susan Fitzgerald, Matina Kourtis, Joan Michaels, Barbara Christensen, William F Seward, Kathleen Hewitt, David R Holmes
BACKGROUND: The Society of Thoracic Surgeons (STS)/American College of Cardiology Transcatheter Valve Therapy (TVT) Registry captures all procedures with Food and Drug Administration-approved transcatheter valve devices performed in the United States, and is mandated as a condition of reimbursement by the Centers for Medicaid & Medicare Services. OBJECTIVES: This annual report focuses on patient characteristics, trends, and outcomes of transcatheter aortic and mitral valve catheter-based valve procedures in the United States...
March 14, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27955994/2016-annual-report-of-the-society-of-thoracic-surgeons-american-college-of-cardiology-transcatheter-valve-therapy-registry
#11
Frederick L Grover, Sreekanth Vemulapalli, John D Carroll, Fred H Edwards, Michael J Mack, Vinod H Thourani, Ralph G Brindis, David M Shahian, Carlos E Ruiz, Jeffrey P Jacobs, George Hanzel, Joseph E Bavaria, E Murat Tuzcu, Eric D Peterson, Susan Fitzgerald, Matina Kourtis, Joan Michaels, Barbara Christensen, William F Seward, Kathleen Hewitt, David R Holmes
BACKGROUND: The Society of Thoracic Surgeons (STS)/American College of Cardiology Transcatheter Valve Therapy (TVT) Registry captures all procedures with Food and Drug Administration-approved transcatheter valve devices performed in the United States, and is mandated as a condition of reimbursement by the Centers for Medicaid & Medicare Services. OBJECTIVES: This annual report focuses on patient characteristics, trends, and outcomes of transcatheter aortic and mitral valve catheter-based valve procedures in the United States...
March 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27939353/three-dimensional-diastolic-blood-flow-in-the-left-ventricle
#12
Seyed Saeid Khalafvand, Eddie Yin-Kwee Ng, Liang Zhong, Tin-Kan Hung
Three-dimensional blood flow in a human left ventricle is studied via a computational analysis with magnetic resonance imaging of the cardiac motion. Formation, growth and decay of vortices during the myocardial dilation are analyzed with flow patterns on various diametric planes. They are dominated by momentum transfer during flow acceleration and deceleration through the mitral orifice. The posterior and anterior vortices form an asymmetric annular vortex at the mitral orifice, providing a smooth transition for the rapid inflow to the ventricle...
January 4, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/27934625/ultrasonographic-findings-in-two-sheep-with-enzootic-calcinosis
#13
U Braun, K Mitchell, S Schramm, S Nogler, J Hatt, A Malbon
This report describes 2 sheep with enzootic calcinosis characterized by abnormal cardiovascular and respiratory findings and ascites causing abdominal distension. Both sheep were anorexic and listless and had increased heart and respiratory rates. Auscultation of the heart revealed a gallop rhythm in sheep 1 and a loud systolic heart murmur in sheep 2. The activities of liver enzymes were severely increased in both sheep. Abdominal ultrasonography showed severe ascites and congestion of the liver and caudal vena cava...
December 2016: Schweizer Archiv Für Tierheilkunde
https://www.readbyqxmd.com/read/27692768/concept-of-an-expandable-cardiac-valve-for-surgical-implantation-in-infants-and-children
#14
Sitaram M Emani, Breanna L Piekarski, David Zurakowski, Christopher A Baird, Audrey C Marshall, James E Lock, Pedro J Del Nido
BACKGROUND: Options for cardiac valve replacement in children are limited to fixed-diameter prostheses that do not accommodate for somatic growth. An externally stented bovine jugular vein graft has been modified for surgical valve replacement in pediatric patients, with the intention of subsequent valve expansion in the catheterization laboratory as the child grows. METHODS: Pediatric patients at a single institution who underwent surgical implantation of an expandable bovine jugular vein valve between 2010 and 2014 were reviewed retrospectively...
December 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27567391/characteristics-and-outcomes-of-indian-children-enrolled-in-a-rheumatic-heart-disease-registry
#15
Anurag Mehta, Anita Saxena, Rajnish Juneja, Sivasubramanian Ramakrishnan, Saurabh Gupta, Shyam Sundar Kothari
BACKGROUND: Rheumatic heart disease (RHD) causes significant morbidity among children of low and middle-income countries. We aimed to assess characteristics and outcomes of Indian children enrolled in a tertiary care hospital RHD registry. METHODS: Pediatric patients (≤18years) were prospectively enrolled over three years. We evaluated their clinical and echocardiographic characteristics, valvular interventions, adherence to penicillin prophylaxis, and mortality...
November 1, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27538860/swine-sus-scrofa-as-a-model-of-postinfarction-mitral-regurgitation-and-techniques-to-accommodate-its-effects-during-surgical-repair
#16
Eric L Sarin, Weiwei Shi, Rajnish Duara, Todd A Melone, Kanika Kalra, Ashley Strong, Apoorva Girish, Bryant V McIver, Vinod H Thourani, Robert A Guyton, Muralidhar Padala
Mitral regurgitation (MR) is a common heart-valve lesion after myocardial infarction in humans. Because it is considered a risk factor for accelerated heart failure and death, various surgical approaches and catheter-based devices to correct it are in development. Lack of a reproducible animal model of MR after myocardial infarction and reliable techniques to perform open-heart surgery in these diseased models led to the use of healthy animals to test new devices. Thus, most devices that are deemed safe in healthy animals have shown poor results in human efficacy studies, hampering progress in this area of research...
2016: Comparative Medicine
https://www.readbyqxmd.com/read/26856218/practice-gaps-in-the-care-of-mitral-valve-regurgitation-insights-from-the-american-college-of-cardiology-mitral-regurgitation-gap-analysis-and-advisory-panel
#17
REVIEW
Andrew Wang, Paul Grayburn, Jill A Foster, Marti L McCulloch, Vinay Badhwar, James S Gammie, Salvatore P Costa, Robert Michael Benitez, Michael J Rinaldi, Vinod H Thourani, Randolph P Martin
BACKGROUND: The revised 2014 American College of Cardiology (ACC)/American Heart Association valvular heart disease guidelines provide evidenced-based recommendations for the management of mitral regurgitation (MR). However, knowledge gaps related to our evolving understanding of critical MR concepts may impede their implementation. METHODS: The ACC conducted a multifaceted needs assessment to characterize gaps, practice patterns, and perceptions related to the diagnosis and treatment of MR...
February 2016: American Heart Journal
https://www.readbyqxmd.com/read/26814651/year-in-review-mitral-valve-surgery
#18
REVIEW
Bobby Yanagawa, David Latter, Subodh Verma
PURPOSE OF REVIEW: In the past year, there has been progress on several fronts in the field of mitral valve surgery and intervention. Here, we review key publications regarding the surgical and transcatheter management of mitral valve disease. RECENT FINDINGS: This past year heralded the publication of the 2014 American Heart Association (AHA)/American College of Cardiology (ACC) Guidelines for the Management of Patients With Valvular Heart Disease. Regarding degenerative mitral regurgitation, low risk of operative mortality and data demonstrating clinical benefit for early surgery are prompting renewed calls for early intervention before guideline-based triggers...
March 2016: Current Opinion in Cardiology
https://www.readbyqxmd.com/read/26727025/chordal-reconstruction-versus-leaflet-resection-for-repair-of-degenerative-posterior-mitral-leaflet-prolapse
#19
COMPARATIVE STUDY
Yeow Leng Chua, Philip Y K Pang, Yen Ping Yap, Zakir Hussain Abdul Salam, Yang Tian Chen
OBJECTIVE: To review our experience of mitral valve repair for degenerative posterior mitral leaflet prolapse, comparing the outcomes of chordal reconstruction and leaflet resection. METHODS: From 2000 to 2014, 205 patients underwent successful repair for degenerative posterior mitral leaflet prolapse. One hundred and four (51.5%) underwent leaflet resection (group R) and 98 (48.5%) underwent chordal reconstruction (group C). Follow-up was 96.5% complete with a mean follow-up of 6...
2016: Annals of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/26566527/cts-trials-network-surgical-ablation-of-atrial-fibrillation-during-mitral-valve-surgery-many-questions-unanswered
#20
Ahmed Afifi
A disease that is associated with stroke and mortality, atrial fibrillation (AF) complicates 30 to 50% of mitral valve disease patients admitted for surgery.(1) Since the introduction of the Cox maze III procedure in 1992 many efforts have been made to come up with modified lesion sets and/or energy sources to surgically treat AF. This lead to the recently published American Heart Association (AHA)- American College of Cardiology (ACC)-Heart Rhythm Society (HRS) guidelines(2) stating that it is reasonable to perform atrial fibrillation ablation in selected patients undergoing other types of cardiac surgery...
2015: Global Cardiology Science & Practice
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