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De-Lei Cheng, Nan Zhu, Cheng-Li Li, Wei-Fu Lv, Wei-Wei Fang, Ya Liu, Chuan-Ting Li
Budd-Chiari syndrome (BCS) is a rare clinical syndrome caused by the obstruction of hepatic venous outflow. In theory, hepatic congestion and hypoxia induce pathological damage and changes in the liver. However, at present, laboratory evidence supporting this theory is lacking. The aim of the present study was to assess the expression and significance of the hypoxia-associated indicators malondialdehyde (MDA), superoxide dismutase (SOD) and endotoxin (ET) in the liver and serum of subjects with BCS. An animal model of BCS was established by partial ligation of the inferior vena cava (IVC) in rats...
December 2018: Experimental and Therapeutic Medicine
Peng Xu, Lulu Lyu, Muhammad Umair Sami, Xin Lu, Haitao Ge, Yutao Rong, Chunfeng Hu, Kai Xu
In recent years, the role of magnetic resonance angiography (MRA) in the diagnosis of Budd-Chiari Syndrome (BCS) has been the focus of various clinical studies. The purpose of the present study was to perform a meta-analysis of the diagnostic performance of MRA in patients with BCS by using digital subtraction angiography as a reference method. The search strategy for relevant research articles was based on the Cochrane Handbook for Systematic Reviews, and literature databases (including PubMed, Medline and China National Knowledge Infrastructure) and reference lists of retrieved studies published from 2000 to 2016 were searched...
December 2018: Experimental and Therapeutic Medicine
Yingying Li, Valerio De Stefano, Hongyu Li, Kexing Zheng, Zhaohui Bai, Xiaozhong Guo, Xingshun Qi
BACKGROUND AND AIMS: The global epidemiological data of Budd-Chiari syndrome (BCS) are scant. A systemic review and meta-analysis aimed to estimate the incidence and prevalence of BCS. METHODS: PubMed, EMBASE, and Cochrane Library databases were searched. The Newcastle-Ottawa Scale was used to assess the study quality. The pooled incidence and prevalence of BCS with 95% confidence intervals (CIs) were calculated by using a random-effect model. The heterogeneity was assessed by the Cochran's Q-test and I2 statistics...
December 7, 2018: Clinics and Research in Hepatology and Gastroenterology
Jiaywei Tsauo, He Zhao, Xiaowu Zhang, Huaiyuan Ma, Mingshan Jiang, Ningna Weng, Xiao Li
OBJECTIVES: To evaluate the changes in arterial oxygenation after portal decompression in Budd-Chiari syndrome (BCS) patients with hepatopulmonary syndrome (HPS). METHODS: From June 2014 to June 2015, all patients with BCS who underwent balloon angioplasty or transjugular intrahepatic portosystemic shunt (TIPS) creation at our institution were eligible for inclusion in this study. Arterial blood gas analysis was performed with the patient in an upright position and breathing room air at 2-3 days and 1 and 3 months after the procedure...
November 30, 2018: European Radiology
Weihao Li, Xuemin Zhang, Tao Zhang, Jingjun Jiang, Zhibin He, Xiaoming Zhang
A case with an extremely rare intravenous cystic lesion in suprahepatic inferior vena cava was reported, which originated from the lymphatic system and had induced Budd-Chiari syndrome. To the best of our knowledge, this is the first report of a benign cystic lesion originating from the wall of suprahepatic inferior vena cava that results in Budd-Chiari syndrome.
November 27, 2018: Annals of Vascular Surgery
Giacomo Emmi, Alessandra Bettiol, Elena Silvestri, Gerardo Di Scala, Matteo Becatti, Claudia Fiorillo, Domenico Prisco
Behçet's syndrome (BS) is a complex vasculitis, characterised by peculiar histological, pathogenetic and clinical features. Superficial venous thrombosis (SVT) and deep vein thrombosis (DVT) are the most frequent vascular involvements, affecting altogether 15-40% of BS patients. Atypical thrombosis is also an important clinical feature of BS, involving the vascular districts of the inferior and superior vena cava, suprahepatic veins with Budd-Chiari syndrome, portal vein, cerebral sinuses and right ventricle...
November 29, 2018: Internal and Emergency Medicine
A H Khan, M M Rahman, M F Rahaman, M Rahman, M K Mondal, M A Chowdhury
Antiphospholipid Syndrome (APS) is characterized by arterial, venous or small vessel thromboses and/or pregnancy morbidity in the presence of persistently elevated titers of antiphospholipid antibodies. Since virtually any organ can be involved, the clinical presentation of APS is very varied. Abdominal manifestations are rare but may be life-threatening, and include Budd-Chiari Syndrome. We report the case of a 26-year-old woman with primary APS, on aspirin treatment, who presented to us at Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh in March 2017 with ascites for which she had been receiving treatment for abdominal tuberculosis...
October 2018: Mymensingh Medical Journal: MMJ
J Collot, N Bletard, A Lamproye
Rarely encountered in the Western countries, membranous occlusion of the inferior vena cava results from a fibrous thickening of the intima and is commonly located at the orifices of the hepatic veins. To date, two etiopathogenic hypotheses have been formulated: the first, dealing with the embryological aspect, the second, arguing for a thrombotic origin. Nevertheless, several studies are still underway to understand the exact physiopathological mechanism of this obstruction. Among these studies, some suspect the predisposing role of anatomical and infectious factors...
November 2018: Revue Médicale de Liège
Rajeev Redkar, Anant Bangar, Varun Hathiramani, Vinod Raj, C Swathi
OBJECTIVE: To study the diagnostic methods and treatment outcomes in children with Budd- Chiari syndrome. METHODS: Case records of 25 patients with Budd-Chiari syndrome were evaluated retrospectively. These patients were investigated with imaging techniques and underwent balloon angioplasty or surgical management. RESULTS: 21 patients underwent balloon angioplasty, of which 17 had good medium- to long-term results, while only one out of four patients who underwent a portocaval shunt survived...
October 15, 2018: Indian Pediatrics
Vanitha Vasudevan, Devendra Chandra Joshi
No abstract text is available yet for this article.
October 15, 2018: Indian Pediatrics
Faisal Khan, Homoyon Mehrzad, Dhiraj Tripathi
Budd-Chiari syndrome (BCS) is a rare but fatal disease caused by the obstruction in hepatic venous outflow tract (usually by thrombosis) and is further classified into two subtypes depending on the level of obstruction. Patients with BCS often have a combination of prothrombotic risk factors. Clinical presentation is diverse. Stepwise management strategy has been suggested with excellent 5-year survival rate. It includes anticoagulation, treatment of identified prothrombotic risk factor, percutaneous recanalization, and transjugular intrahepatic portosystemic shunt (TIPS) to reestablish hepatic venous outflow and liver transplantation in unresponsive patients...
September 2018: Journal of Translational Internal Medicine
Yonghua Bi, Hongmei Chen, Pengxu Ding, Pengli Zhou, Xinwei Han, Jianzhuang Ren
This study aimed to evaluate the long-term efficacy and safety of percutaneous transhepatic balloon angioplasty (PTBA) and transjugular intrahepatic portosystemic stent-shunt (TIPSS) in the treatment of Budd-Chiari syndrome (BCS) with hepatic veins involvement. Between June 2008 and August 2016, a total of 60 BCS patients with hepatic vein involvement in our department were enrolled in this study. Thirty-three cases underwent hepatic vein balloon angioplasty in PTBA Group and 27 cases underwent TIPSS. Data were retrospectively collected, and follow-up observations were performed...
October 2018: Medicine (Baltimore)
De-Lei Cheng, Nan Zhu, Hao Xu, Cheng-Li Li, Wei-Fu Lv, Wei-Wei Fang, Chuan-Ting Li
To date, interventional therapy for patients with Budd-Chiari syndrome (BCS) due to hepatic vein obstruction (HVO) has not been standardized in China. In Western countries, BCS primarily occurs due to thrombosis and the majority of patients receive thrombolysis. In China, BCS is mostly caused by the membranous occlusion of the HV or IVC. The present retrospective study evaluated the efficacy of recanalization techniques in patients with primary BCS due to HVO. The data of 69 patients with BCS due to HVO, who underwent endovascular therapy at 2 centers in China between December 2010 and December 2012, were analyzed...
November 2018: Experimental and Therapeutic Medicine
Kemal Murat Haberal, Feride Kural Rahatlı, Hale Turnaoğlu, Gonca Özgün, Mehmet Coşkun
OBJECTIVES: Computed tomography liver volumetry has been widely used to detect total and segmental liver volume in living-donor liver transplantation. However, use of this technique to evaluate the cirrhotic liver remains unclear. In this study, we evaluated the accuracy of freehand computed tomography volumetry to assess total liver volume by comparing weights of total hepatectomy specimens in patients with cirrhosis. For our analyses, we considered the density of a cirrhotic liver to be 1...
November 6, 2018: Experimental and Clinical Transplantation
Ross Apostolov, Anthony Schelleman, Paul Gow
No abstract text is available yet for this article.
November 2018: Lancet. Gastroenterology & Hepatology
Qingle Li, Tao Zhang, Dashuai Wang, Wei Li, Xuemin Zhang, Xiaoming Zhang
OBJECTIVE: Therapies for Budd-Chiari syndrome (BCS) can be divided into three main categories: medical, endovascular, and surgical. Surgery is applicable to the disease when other therapeutic options have failed. We introduce a surgical method of recanalization through exposure of the entire hepatic inferior vena cava (IVC) and hepatic vein (HV) outflow tract for BCS and investigate the long-term outcomes. METHODS: From July 2002 to December 2015 in our center, 83 consecutive symptomatic BCS patients with failure of endovascular therapy were treated by radical surgical recanalization...
October 16, 2018: Journal of Vascular Surgery. Venous and Lymphatic Disorders
Lei Su, Liyang Chang, Qiang Sun, Lili Hu, Yan Wu, Jianbo Gao
OBJECTIVE: To assess the quality and diagnostic accuracy of monochromatic images combined with adaptive statistical iterative reconstruction (ASIR) performed via spectral computed tomography (CT) in patients with Budd-Chiari syndrome (BCS). METHODS: Sixty-two patients with BCS underwent pectral CT with upper abdominal two-phase contrast-enhanced scanning to generate a 60keV monochromatic energy level combined with ASIR (ranging from 0% -100%) during the portal venous phase (PVP) and the hepatic venous phase (HVP)...
2018: PloS One
Hao Xiang, Jason Han, William E Ridley, Lloyd J Ridley
No abstract text is available yet for this article.
October 2018: Journal of Medical Imaging and Radiation Oncology
Abdisamad M Ibrahim, Bishal Bhandari, Paolo K Soriano, Zafar Quader, John Z Gao, Dmitry Shuster, Chaitanya K Mamillapalli
BACKGROUND Sarcoidosis is a systemic disease that can affect any organ, including the liver. It is manifested by the presence of non-caseating granulomas within involved organs, most commonly the pulmonary, lymphatic, and hepatic system. Unlike pulmonary or lymphatic involvement, hepatic involvement is usually asymptomatic and it is underdiagnosed. Here, we report a case of a patient with a history of pulmonary sarcoidosis who developed hepatic sarcoidosis. CASE REPORT 68-year-old female with pulmonary sarcoidosis with a 2-week history of severe abdominal pain and epigastric tenderness presented to our center...
October 11, 2018: American Journal of Case Reports
Amar Mukund, Shiv Kumar Sarin
No abstract text is available yet for this article.
November 2018: Hepatology International
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