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https://www.readbyqxmd.com/read/30317627/risk-factors-and-therapies-in-vascular-diseases-an-umbrella-review-of-updated-systematic-reviews-and-meta-analyses
#1
REVIEW
Xing-Yu Hong, Jie Lin, Wei-Wei Gu
Aberrant blood vessel functioning and systemic circulation are key causes for vascular disorders; cardiovascular, cerebrovascular, renal artery stenosis, and peripheral artery diseases. Epidemiological and basic science evidence supported genetic reasons, compounded by obesity, hypercholesterolemia, hypertension, diabetes, and smoking as risk factors. This is an umbrella review of risk factors and therapies in vascular disorders, exploring systematic reviews and meta-analyses studies in PubMed, Cochrane, Embase, and Central published in January 2000-May 2018...
October 14, 2018: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/30312221/impact-of-disgust-on-intentions-to-undergo-colorectal-surgery
#2
Megan C Turner, Julia D O'Brien, Rachel M Kahn, Christopher R Mantyh, John Migaly, Dan Ariely
BACKGROUND: Surgeons present patients with complex information at the perioperative appointment. Emotions likely play a role in surgical decision-making, and disgust is an emotion of revulsion at a stimulus that can lead to avoidance. OBJECTIVE: The purpose of this study was to determine the impact of disgust on intention to undergo surgical resection for colorectal cancer and recall of perioperative instructions. DESIGN: This was a cross-sectional observational study conducted online using hypothetical scenarios with nonpatient subjects...
October 11, 2018: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/30312156/sequential-organ-failure-assessment-sofa-to-predict-pressure-ulcer-risk-in-intensive-care-patients-a-retrospective-cohort-study
#3
Maarit Ahtiala, Esa Soppi, Teijo Saari
Pressure ulcer (PU) risk assessment practices in adult intensive care unit (ICU) patients remain varied. PURPOSE: The authors assessed the performance of the Sequential Organ Failure Assessment (SOFA) scale and its subcategories in predicting the development of PUs. METHODS: A retrospective cohort study was conducted of all adult patients admitted to the mixed medical-surgical ICU of a Finnish tertiary referral hospital between January 2010 and December 2012. Data (diagnoses, demographics, clinical information, treatments, and instrument scores) were retrieved from the ICU database...
October 2018: Ostomy/wound Management
https://www.readbyqxmd.com/read/30308615/implant-based-breast-reconstruction-with-acellular-dermal-matrix-safety-data-from-an-open-label-multicenter-randomized-controlled-trial-in-the-setting-of-breast-cancer-treatment
#4
Fredrik Lohmander, Jakob Lagergren, Pankaj G Roy, Hemming Johansson, Yvonne Brandberg, Catharina Eriksen, Jan Frisell
OBJECTIVE: To evaluate clinical outcomes of using acellular dermal matrix (ADM) with implant based breast reconstructions (IBBRs) in a randomized controlled trial. SUMMARY BACKGROUND DATA: The use of ADMs in IBBRs is widespread, but link between ADM and complications remain a controversial topic. In view of reports concerning harm, we present 6-months safety data of ADM-assisted IBBR in the setting of breast cancer treatment. METHODS: An open-label, randomized, controlled trial recruiting patients from 4 centers in Sweden and 1 in UK...
October 10, 2018: Annals of Surgery
https://www.readbyqxmd.com/read/30306921/the-impact-of-telementoring
#5
Hege Kristin Andreassen, Line Lundvoll Warth
Telementoring is a well-known practice in surgical training, and its impact is traditionally related to individual surgeons' performance and the quality of the procedure. The objective of this study was to explore telementoring in a wider organisational context. This paper reports on an ethnographic study carried out during 2014-2016 in Norway, combining observations, interviews, focus groups and field notes. We followed the surgical training of a specialist candidate at a medium-sized surgical ward. The training successfully took place through the use of telementoring, comprising updated standards for a surgical procedure that ensured minimum invasive surgery for a vulnerable patient group...
2018: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/30303886/predicting-the-risk-of-readmission-from-dehydration-after-ileostomy-formation-the-dehydration-readmission-after-ileostomy-prediction-score
#6
Sophia Y Chen, Miloslawa Stem, Marcelo Cerullo, Joseph K Canner, Susan L Gearhart, Bashar Safar, Sandy H Fang, Jonathan E Efron
BACKGROUND: All-cause readmission rates in patients undergoing ileostomy formation are as high as 20% to 30%. Dehydration is a leading cause. No predictive model for dehydration readmission has been described. OBJECTIVE: The purpose of this study was to develop and validate the Dehydration Readmission After Ileostomy Prediction scoring system to predict the risk of readmission for dehydration after ileostomy formation. DESIGN: Patients who underwent ileostomy formation were identified using the American College of Surgeons National Surgical Quality Improvement Program data set (2012-2015)...
October 9, 2018: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/30300664/expression-of-amino-acid-transporter-lat1-and-4f2hc-in-pulmonary-pleomorphic-carcinoma
#7
Kyoichi Kaira, Osamu Kawashima, Hedeki Endoh, Kazuyoshi Imaizumi, Yasuhiro Goto, Mitsuhiro Kamiyoshihara, Masayuki Sugano, Ryohei Yamamoto, Takashi Osaki, Shigefumi Tanaka, Atsushi Fujita, Hisao Imai, Yoshihito Kogure, Yukio Seki, Kimihiro Shimizu, Akira Mogi, Yoshinori Shitara, Tetsunari Oyama, Yoshikatsu Kanai, Takayuki Asao
Amino acid transporters are necessary for tumor growth, metastasis, and survival of various neoplasms; however, the clinicopathological significance of L-type amino acid transporter 1 (LAT1) and 4F2 cell surface antigen (4F2hc) in patients with pulmonary pleomorphic carcinoma (PPC) remains unknown. The aim of this study is to clarify the prognostic impact of these amino acid transporters in PPC. One hundred and five patients with surgically resected PPC were assessed by immunohistochemistry. The expression of LAT1 and 4F2hc, and Ki-67 labeling index were investigated using specimens of the resected tumors...
October 6, 2018: Human Pathology
https://www.readbyqxmd.com/read/30297304/reducing-repeat-imaging-in-hepato-pancreatico-biliary-surgical-cancer-care-through-shared-diagnostic-imaging-repositories
#8
Julie Hallet, Natalie G Coburn, Amanda Alberga, Longdi Fu, Sukirtha Tharmalingam, Kaitlyn Beyfuss, Laurent Milot, Calvin H L Law
BACKGROUND: With regionalization of care, patients often undergo treatment in institutions other than where the initial investigation is conducted. This study assessed the impact of a shared diagnostic imaging repository (SDIR) on processes of care and outcomes in hepato-pancreatico-biliary (HPB) cancer surgery. METHODS: Provincial administrative datasets were linked to study HPB cancer patients operated at a regional cancer centre (2003-2014). SDIR and non-SDIR groups were based on where initial imaging (CT or MRI) was conducted...
October 5, 2018: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/30296421/outcomes-of-valve-repair-for-degenerative-disease-in-patients-with-mitral-annular-calcification
#9
Anton Tomšič, Yasmine L Hiemstra, Thomas J van Brakel, Michel I M Versteegh, Nina Ajmone Marsan, Robert J M Klautz, Meindert Palmen
BACKGROUND: The predictors for the development of MAC in degenerative mitral valve disease and the effect it may have on patient- and valve-related outcomes require further evaluation. METHODS: Between 1/2002 and 12/2015, 627 patients underwent mitral valve surgery for degenerative disease. MAC was seen in 75 (12%) patients; 73 (97%) underwent valve repair (6 without annuloplasty ring implantation) while 2 (3%) underwent valve replacement after an unsuccessful repair attempt...
October 5, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/30294897/the-risk-of-venous-thromboembolism-during-and-after-hospitalisation-in-patients-with-inflammatory-bowel-disease-activity
#10
Thomas P C Chu, Matthew J Grainge, Timothy R Card
BACKGROUND: Inflammatory bowel disease (IBD) increases the risk of venous thromboembolism. AIM: To determine when patients are at high risk of thromboembolic events, including after major surgery, and to guide timing of thromboprophylaxis. METHODS: Each IBD patient from Clinical Practice Research Datalink, linked with Hospital Episode Statistics, was matched to up to five non-IBD patients in this cohort study. We examined their risk of thromboembolism in hospital and within 6 weeks after leaving hospital, with or without undergoing major surgery, and while ambulant...
October 8, 2018: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/30293901/circulating-thrombospondin-2-enhances-prediction-of-malignant-intraductal-papillary-mucinous-neoplasm
#11
Rachel E Simpson, Michele T Yip-Schneider, Huangbing Wu, Hao Fan, Ziyue Liu, Murray Korc, Jianjun Zhang, C Max Schmidt
BACKGROUND: IPMNs are cystic pancreatic lesions with variable malignant potential. Thrombospondin-2 (THBS2)-an endogenous, anti-angiogenic matrix glycoprotein-may modulate tumor progression. We hypothesized that circulating levels of THBS2 could aid in preoperative prediction of malignant IPMN. METHODS: Preoperative serum/plasma samples were procured from patients undergoing surgery. Circulating levels of THBS2 were measured (enzyme-linked immunosorbent assay) and compared to surgical pathology IPMN dysplastic grade...
September 7, 2018: American Journal of Surgery
https://www.readbyqxmd.com/read/30293474/changes-of-arterial-pressure-following-relief-of-obstruction-in-adults-with-hydronephrosis
#12
Ammar Al-Mashhadi, Michael Häggman, Göran Läckgren, Sam Ladjevardi, Tryggve Nevéus, Arne Stenberg, A Erik G Persson, Mattias Carlström
BACKGROUND: As much as 20% of all cases of hypertension are associated with kidney malfunctions. We have previously demonstrated in animals and in pediatric patients that hydronephrosis causes hypertension, which was attenuated by surgical relief of the ureteropelvic junction (UPJ) obstruction. This retrospective cohort study aimed to investigate: (1) the proposed link between hydronephrosis, due to UPJ obstruction, and elevated arterial pressure in adults; and (2) if elevated blood pressure in patients with hydronephrosis might be another indication for surgery...
October 8, 2018: Upsala Journal of Medical Sciences
https://www.readbyqxmd.com/read/30293133/gut-microbiota-imbalance-can-be-associated-with-non-malabsorptive-small-bowel-shortening-regardless-of-blind-loop
#13
Eduardo Lemos de Souza Bastos, Ana Maria Alvim Liberatore, Roberto Carlos Tedesco, Ivan Hong Jun Koh
INTRODUCTION: Some traditional bariatric surgery procedures may lead to functional gut shortening, which may unsettle the fine-tuned gastrointestinal physiology and affect gut microbiota balance. PURPOSE: Evaluate the gut microbiota behavior in rat models facing gut shortening due to intestinal bypass. MATERIALS AND METHODS: Wistar rats (n = 17) were randomly distributed in three groups: (1) sham group (n = 5); (2) blind loop group (n = 6); and (3) resection group (n = 6)...
October 6, 2018: Obesity Surgery
https://www.readbyqxmd.com/read/30292618/serum-resistin-is-associated-with-impaired-endothelial-function-and-a-higher-rate-of-adverse-cardiac-events-in-patients-with-peripheral-artery-disease
#14
Joel L Ramirez, Sukaynah A Khetani, Greg J Zahner, Kimberly A Spaulding, Melinda S Schaller, Warren J Gasper, Nancy K Hills, Anne L Schafer, S Marlene Grenon
OBJECTIVE: Resistin is a hormone that has been associated with metabolic syndrome and cardiovascular disease. The role of resistin in patients with peripheral artery disease (PAD) has not been fully explored. This study seeks to understand the relationship between serum resistin, vascular function, and cardiovascular outcomes in patients with PAD. METHODS: There were 106 patients with PAD who were recruited between 2011 and 2016. Patients attended a baseline visit during which a comprehensive vascular physiology assessment including medical and surgical history, radial artery tonometry, and flow mediated-vasodilation (FMD) was completed...
October 3, 2018: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/30292612/aortoiliac-calcification-correlates-with-5-year-survival-after-abdominal-aortic-aneurysm-repair
#15
Matthew J TerBush, Khurram Rasheed, Zane Z Young, Jennifer L Ellis, Roan J Glocker, Adam J Doyle, Kathleen G Raman, Michael C Stoner
BACKGROUND: An anatomic severity grade (ASG) score to categorize and to define anatomic factors for abdominal aortic aneurysm (AAA) repair was proposed. Other studies have previously reported that aortic anatomic complexity is a marker of survival and resource utilization after repair, although it remains unclear whether individual components of the ASG score independently contribute to survival. This study analyzed and validated an aortic and iliac artery calcium scoring system that can potentially predict survival after AAA repair...
October 3, 2018: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/30291032/ten-year-epidemiological-study-in-an-orthopaedic-and-trauma-surgery-centre-are-there-risks-involved-in-increasing-scheduled-arthroplasty-volume-without-increasing-resources
#16
Roger Erivan, Thibault Chaput, Guillaume Villatte, Matthieu Ollivier, Stéphane Descamps, Stéphane Boisgard
BACKGROUND: Current trends in patient management include decreasing hospital stay lengths and reductions in available material and human resources. A shortening of hospital stays in university hospitals has been documented over the last decade. However, to our knowledge, no study has assessed possible relationships linking shorter stays to staffing levels or complication rates. The objectives of this study were: 1) to assess changes in case volume in a university orthopaedics and trauma surgery department between 2006 and 2016, 2) and to look for correlations linking these changes to staffing levels and the rates of significant complications, including the number of hip dislocations after total hip arthroplasty (THA) and the number of infections and complications resulting in malpractice litigation after hip, knee, or shoulder arthroplasty...
October 2, 2018: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/30291020/prognostic-factors-and-management-of-patients-with-choanal-atresia
#17
Eric Moreddu, Marie-Eva Rossi, Richard Nicollas, Jean-Michel Triglia
OBJECTIVE: To analyze prognostic factors in the management of patients with choanal atresia. STUDY DESIGN: This is a review of 114 patients operated on for choanal atresia in a tertiary care center between November 1986 and November 2016, including clinical characteristics, surgical management, and postoperative course with final nasal patency. The data were collected in a database that was updated over time. RESULTS: Among the 114 patients, 78 were female, 77 presented with unilateral choanal atresia, and 37 presented with bilateral unilateral choanal atresia, corresponding to 151 nasal fossae...
October 2, 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/30289842/what-effect-does-smoking-have-on-the-surgical-closure-of-tympanic-membrane-perforations-a-review
#18
Vikranth Visvanathan, Vamsidhar Vallamkondu, Sanjiv K Bhimrao
OBJECTIVES: The link between cigarette smoking and outcome following surgical repair of tympanic membrane perforation is unclear. The objective of this study was to conduct a systematic review on the link between smoking and success rate following surgical repair of tympanic membrane perforations. MATERIALS AND METHODS: Systematic review performed using the following data sources: 1) Cochrane central register of controlled trials (1997 to April 30, 2018), 2) Medline (February 1948 to April 30, 2018), and 3) Embase (1975 to April 30, 2018)...
October 4, 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/30286376/a-material-modeling-approach-for-the-effective-response-of-planar-soft-tissues-for-efficient-computational-simulations
#19
Will Zhang, Rana Zakerzadeh, Wenbo Zhang, Michael S Sacks
One of the most crucial aspects of biomechanical simulations of physiological systems that seek to predict the outcomes of disease, injury, and surgical interventions is the underlying soft tissue constitutive model. Soft tissue constitutive modeling approaches have become increasingly complex, often utilizing meso- and multi-scale methods for greater predictive capability and linking to the underlying biological mechanisms. However, such modeling approaches are associated with substantial computational costs...
September 20, 2018: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/30284246/functional-electrical-stimulation-leads-to-increased-volume-of-the-aged-thyroarytenoid-muscle
#20
Markus Gugatschka, Jonathan C Jarvis, Justin D Perkins, Vladimir Bubalo, Iris Wiederstein-Grasser, Hermann Lanmüller, Claus Gerstenberger, Michael Karbiener
OBJECTIVES/HYPOTHESIS: To reverse sarcopenia and increase the volumes of atrophied laryngeal muscles by functional electrical stimulation (FES) using a minimal invasive surgical procedure in an aged ovine model. STUDY DESIGN: Prospective animal study. METHODS: A stimulation electrode was placed unilaterally near the terminal adduction branch of the recurrent laryngeal nerve (RLN) adjacent to the right cricothyroid joint. The electrode was connected to an implant located subcutaneously at the neck region...
October 3, 2018: Laryngoscope
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