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Lymphatic malformation

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https://www.readbyqxmd.com/read/28087956/intralesional-injection-of-ok-432-in-cystic-hygroma
#1
M Hazim, S S Moses, I P Tan
BACKGROUND: Lymphangiomas are congenital malformations of the lymphatic system with characteristic dilated endothelium-lined spaces. It is vulnerability to infection or chemical irritants cause spontaneous reduction in size and in some cases complete resolution. Intralesional injection of OK-432 or Picibanil (lyophilized incubation mixture of Group A Streptococcus pyogenes of human origin) is slowly gaining recognition as its safety and efficacy standards have shown to avoid complications resulting from surgical interventions...
December 2016: Medical Journal of Malaysia
https://www.readbyqxmd.com/read/28064298/case-report-of-a-chest-wall-cystic-hygroma-in-a-teenager
#2
K Aimanan, M P Putera, L G Chew, T Ramesh, M I Muhd Azim, B Badmanaban
Cystic hygroma or cystic lymphangioma is a congenital malformation of lymphatic origin. Their occurrence on the chest wall is very rare, and they progressively grow with age infiltrating into the local tissues, around muscle fibers and nerves, making them difficult and hazardous to remove. There are various treatment modalities of such lesion. Based on the literature surgical excision is the preferred treatment of choice in cystic hygroma because it gives a better cure rate compared to other modalities. We report a case successful excision of anterolateral chest wall cystic hygroma in a teenager in Hospital Serdang...
October 2016: Medical Journal of Malaysia
https://www.readbyqxmd.com/read/28062382/fourteen-years-follow-up-of-massive-pelvic-girdle-osteolysis-caused-by-lymphatic-malformation-gorham-stout-disease
#3
Richard Ballas, Madeline Caduc, Jordan Ovigue, Philippe Elkienbaum, Frédérique Sauvat
No abstract text is available yet for this article.
January 3, 2017: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/28024668/potential-risks-of-maternal-administration-of-mucophylline-on-the-pups-of-albino-rats-during-lactation
#4
Hamida Hamdi, Heba Ali
The present study was undertaken to evaluate the potential risks of the mucolytic and broncholytic drug, Theophylline derivatives (Mucophylline) maternally administered on the pups. The nursing rats orally administered from 1st postpartum day (PPD) to 21th PPD with two different doses 30.83mg/kg (low dose) and 66.61mg/kg (Human equivalent dose (HED)). On the 21th PPD, the postnatal developmental signs, skeletal malformation and the histopathology of neonatal liver, kidney and brain were examined. Our results showed that Mucophylline induced a significant reduction in the neonatal weight and length, delayed, weak and incomplete ossification, wavy ribs and the neonatal liver revealed histopathological changes, pyknotic hepatocytes, cytoplasmic vacuolization, dilated sinusoid and necrotic area...
December 23, 2016: Experimental and Toxicologic Pathology: Official Journal of the Gesellschaft Für Toxikologische Pathologie
https://www.readbyqxmd.com/read/28004970/intraabdominal-lymphatic-malformations-pearls-and-pitfalls-of-diagnosis-and-differential-diagnoses-in-pediatric-patients
#5
Michael L Francavilla, Candace L White, Brandon Oliveri, Edward Y Lee, Ricardo Restrepo
OBJECTIVE: The purpose of this article is to review the practical imaging workup and characteristic imaging appearances of intraabdominal lymphatic malformations (LMs) in the pediatric population with a brief discussion of some common differential diagnoses found in a vascular anomaly clinic. CONCLUSION: LMs are uncommon pediatric lesions. Because of their rarity among LMs overall, a tendency to present later in life than superficial LMs, and often incidental identification, intraabdominal LMs pose a particular diagnostic challenge, and pathologic entities that are more prevalent must be carefully excluded first...
December 22, 2016: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/27993327/percutaneous-treatment-of-lymphatic-malformations
#6
REVIEW
Michael Acord, Abhay S Srinivasan, Anne Marie Cahill
Lymphatic malformations are slow-flow vascular anomalies composed of dilated lymphatic channels and cysts of varying sizes. Percutaneous treatments, particularly sclerotherapy, play an important role in the treatment of these lesions, often obviating the need for surgical intervention. Owing to the complex nature of these lesions, a multidisciplinary approach should be used to guide diagnosis and management. This submission focuses on the workup and treatment of pediatric lymphatic malformations at our institution, with a focus on sclerotherapy...
December 2016: Techniques in Vascular and Interventional Radiology
https://www.readbyqxmd.com/read/27990304/nonneoplastic-tongue-swellings-of-lymphatic-and-lymphocytic-origin-three-case-reports
#7
Manar A Abdul Aziz, Nermin M Yussif
Tongue is formed of a mass of muscles and salivary gland embedded in anterior highly vascular and posterior lymphoid stroma and covered by specialized surface epithelium. Growths from all of these heterogonous components may occur resulting in a wide variation in clinical features and behavior, ranging from self-limiting to aggressive lesions. Therefore, surgical excision is the treatment of choice. The aim of the current study is to report three different lesions that came to the Oral Surgery Department in the Faculty of Oral and Dental Medicine, Cairo University...
2016: Case Reports in Dentistry
https://www.readbyqxmd.com/read/27989359/complications-in-head-and-neck-surgery
#8
Emily Christison-Lagay
Head and neck anatomy is topographically complex and the region is densely populated by vital nerves and vascular and lymphatic structures. Injury to many of these structures is associated with significant morbidity and may even be fatal. A thorough knowledge of regional anatomy is imperative and complications need to be managed in a thoughtful directed manner. The pediatric surgeon may be called upon to address both congenital and acquired conditions and should be prepared to encounter reoperative fields after failed initial surgery...
December 2016: Seminars in Pediatric Surgery
https://www.readbyqxmd.com/read/27941746/klippel-trenaunay-syndrome-a-case-report
#9
M N Islam, M A Hossain, M S Rahman, T Tazmin, M A Ali, F Sultana, S A Haque
Klippel Trenaunay syndrome refers to a rare congenital anomaly which is characterized by capillary malformation, venous malformation and sometimes lymphatic malformation associated with overgrowth of a limb, with soft tissue hypertrophy and/or bony hypertrophy. The anomaly, if present, is present at birth and usually involves the lower limbs as well as portion of trunk, face, uppper limb or head. Our reporting case is a preterm male neonate having port wine stain, varicose veins and excessive growth of soft tissue of left lower limb clinically consistent with Klippel Trenaunay Syndrome...
October 2016: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/27941161/angiopoietin-tie-signalling-in-the-cardiovascular-and-lymphatic-systems
#10
REVIEW
Lauri Eklund, Jaakko Kangas, Pipsa Saharinen
Endothelial cells that form the inner layer of blood and lymphatic vessels are important regulators of vascular functions and centrally involved in the pathogenesis of vascular diseases. In addition to the vascular endothelial growth factor (VEGF) receptor pathway, the angiopoietin (Ang)-Tie system is a second endothelial cell specific ligand-receptor signalling system necessary for embryonic cardiovascular and lymphatic development. The Ang-Tie system also regulates postnatal angiogenesis, vessel remodelling, vascular permeability and inflammation to maintain vascular homoeostasis in adult physiology...
January 1, 2017: Clinical Science (1979-)
https://www.readbyqxmd.com/read/27922488/intraoperative-assessment-of-facial-nerve-trunk-width-in-early-childhood-with-cervicofacial-lymphatic-malformation
#11
Ara Kim, Jeong-Meen Seo, So Young Lim
BACKGROUND: Facial nerve damage during head and neck surgery has long been an important issue. However, few publications on the gross anatomy of the facial nerve are available in the young population. The aim of this study was to provide in vivo measurements of the facial nerve trunk during lymphatic malformation (LM) resection and to determine the association between the trunk width and patient- and disease-related variables. METHODS: We conducted a retrospective analysis of 11 consecutive pediatric patients (11 facial nerve trunks) who underwent cervicofacial LM resection...
December 2, 2016: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/27911069/-urological-pathology-of-lymphatic-origin
#12
A Domènech, A Serrano, I Forner-Cordero, F Gómez, D Maldonado, C Domínguez
OBJECTIVES: Lymphatic disease is a rarely cause of some very unspecific genitourinary manifestations, assuming a diagnostic challenge in most cases. The aim of this paper is to warn about the possible etiology of these urological lymphatic presentations and discuss its management. METHODS: Retrospective review of clinical data in pediatric patients with urological pathology of lymphatic origin between 2008-2014. Three patients, two boys and a girl, were included...
January 25, 2016: Cirugía Pediátrica: Organo Oficial de la Sociedad Española de Cirugía Pediátrica
https://www.readbyqxmd.com/read/27879620/recurrent-orbital-inflammation-mimicking-orbital-cellulitis-associated-with-orbitopalpebral-venous-lymphatic-malformation
#13
Alicia Galindo-Ferreiro, Hind M Alkatan, Sahar M ElKhamary, Saif AlDosairi, A Augusto V Cruz
An 8-year-old boy initially presented with an orbitopalpebral mass diagnosed clinically and radiologically as a low-flow diffuse venous lymphatic malformation involving the left upper eyelid and orbit. Over 8 months of follow up, he had 2 acute episodes of severe orbital inflammation that warranted hospitalization and treatment with intravenous antibiotic, steroids and surgical debulking. After a third surgical excision, the lesion remained clinically stable.
November 22, 2016: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/27878447/morbidity-and-healthcare-costs-of-vascular-anomalies-a-national-study
#14
Jina Kim, Zhifei Sun, Harold J Leraas, Uttara P Nag, Ehsan Benrashid, Alexander C Allori, Waleska M Pabon-Ramos, Henry E Rice, Cynthia K Shortell, Elisabeth T Tracy
PURPOSE: This study aimed to define morbidities and costs related to modern-day medical care for children with vascular anomalies. METHODS: We reviewed the 2003-2009 Kids' Inpatient Database for pediatric patients (age < 21 years) hospitalized with hemangioma, arteriovenous malformation (AVM), or lymphatic malformation (LM). Patient characteristics, hospital complications, and hospital charges were compared by vascular anomaly type. Multivariable linear regression modeling was used to determine predictors of increasing hospital costs for patients with AVMs...
November 22, 2016: Pediatric Surgery International
https://www.readbyqxmd.com/read/27846771/an-8-year-population-description-from-a-national-treatment-centre-on-lymphatic-malformations
#15
Jill Josefine Eliasson, Inanna Weiss, Hans Erik Høgevold, Nina Oliver, Rune Andersen, Kirsti Try, Kim Alexander Tønseth
INTRODUCTION: Lymphatic malformations are rare developmental non-malignant abnormalities that present as masses consisting of abnormal growth of fluid filled channels or spaces in the skin or deep tissue that result in abnormalities of lymphatic flow. They may cause symptoms like pain, recurrent lymphorrea, abnormal bone growth, and disturbance of bodily functions. They may also be a cosmetic problem. The study aims to describe the population with lymphatic malformations (LM) treated at a national referral centre...
November 16, 2016: Journal of Plastic Surgery and Hand Surgery
https://www.readbyqxmd.com/read/27836363/prenatal-growth-characteristics-of-lymphatic-malformations
#16
William H Peranteau, Suzanne D Iyoob, Matthew M Boelig, Nahla Khalek, Julie S Moldenhauer, Mark P Johnson, Holly L Hedrick, Alan W Flake, Beverly G Coleman, N Scott Adzick
PURPOSE: The natural history of prenatally diagnosed lymphatic malformations (LM) remains unknown. The ability to predict growth of a lesion is important to prenatal counseling and any future prenatal intervention. We describe the prenatal growth patterns of LMs as they relate to gestational age, anatomical location, and postnatal management. METHODS: A retrospective review of fetuses prenatally diagnosed with an LM who were followed with serial ultrasounds from 2003 to 2014 was performed with attention to the growth of the lesion as indicated by the lesion volume ratio (LVR)...
January 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/27826976/patients-with-klippel-trenaunay-syndrome
#17
M Zavacka, J Pobehova, K Gibarti, M Frankovicova
Klippel-Trenaunay syndrome is the most frequent systemic venous angiodysplasia. It is characterized by cutaneous capillary malformations - naevus flammeus, excessive growth of soft and bone tissue, venous and lymphatic malformations. Investigative methods include: clinical examinations, venography as the evidence of dysplastic changes of superficial and / or deep venous system, the Moyne obstruction and venous insufficiency perforator. Treatment is conservative, related to that of chronic venous disease. The surgery is aimed at removing the varices and insufficient perforators (Fig...
2016: Bratislavské Lekárske Listy
https://www.readbyqxmd.com/read/27795797/-cystic-lymphangioma-on-the-floor-of-the-oral-cavity-extending-to-the-submandibular-region-in-adult-patients
#18
Elboukhari Ali, Nador Karim, Attifi Hicham, Zalagh Mohamed
Cystic lymphangiomas are congenital benign lesions occurring predominantly in the head and neck area, especially in the posterior cervical triangle. These malformations involving the lymphatic vessels are frequently diagnosed in children. We report the clinical case of a 28-year-old adult patient with cystic lymphangioma on the floor of the oral cavity extending gradually to the left submandibular region. The clinically suspected tumor was thoroughly explored using tomodensitometry. The treatment consisted of complete resection, endo-orally performed, associated with histological examination confirming the macroscopic diagnosis of cystic lymphangioma...
2016: Pan African Medical Journal
https://www.readbyqxmd.com/read/27790546/bilateral-renal-lymphangiectasia
#19
Vaidehi K Pandya, Maulin K Shah, Shruti P Gandhi, Himanshu V Patel
Renal Lymphangiectasia (RLM) is very rare benign lymphatic malformation. It can be misdiagnosed for other cystic renal masses, most commonly polycystic kidneys. Though incidentally found in most cases, it may be the cause for hypertension and renal failure in undiagnosed patients. Here, we report a case of an adult asymptomatic male with bilateral RLM which was detected as an incidental finding on ultrasound. Confirmation by CT-scan and laboratory diagnosis of aspirated fluid was done, and patient was managed conservatively...
September 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27789267/surgical-excision-with-bleomycin-irrigation-a-better-primary-treatment-choice-for-pediatric-submandibular-lymphatic-malformations
#20
Lei Jin, Jiarui Chen, Xiaoyan Li
PURPOSE: To compare the efficacy of surgical excision combined with intralesional bleomycin irrigation with that of needle aspiration with intralesional bleomycin sclerotherapy (IBS) in pediatric submandibular lymphatic malformations (LMs). MATERIALS AND METHODS: The medical records of 32 patients were analyzed. Clinical response was categorized by improvement in size as determined by imaging studies and calculations of lesion volume. An excellent response was defined as a decrease in volume greater than 90%, a satisfactory response was defined as a decrease greater than 50%, and a poor response was defined as a decrease less than 50%...
September 30, 2016: Journal of Oral and Maxillofacial Surgery
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