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Salivary steroid hormone

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https://www.readbyqxmd.com/read/30469084/assay-validation-of-hair-androgens-across-the-menstrual-cycle
#1
Wen Wang, Shannin N Moody, Jeff Kiesner, Anna Tonon Appiani, Olivia C Robertson, Elizabeth A Shirtcliff
INTRODUCTION: Saliva is a common noninvasive biofluid for measuring stress and sex hormones, yet one pressing limitation is that salivary hormones fluctuate momentarily, daily, and (for girls) across the menstrual cycle. Hair steroid assays are thought to provide a cumulative index which collapses across hormonal variability, potentially eliminating the confound of daily and menstrual cyclicity and thereby reflecting individual differences in average hormone levels. Here we seek to validate a hair bioassay methodology and test whether hair androgens accurately measure long-term, stable androgen levels in emerging adult women across two menstrual cycles...
October 28, 2018: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/30408721/salivary-cortisone-as-a-biomarker-for-psychosocial-stress-is-associated-with-state-anxiety-and-heart-rate
#2
Yoon Ju Bae, Janis Reinelt, Jeffrey Netto, Marie Uhlig, Anja Willenberg, Uta Ceglarek, Arno Villringer, Joachim Thiery, Michael Gaebler, Juergen Kratzsch
BACKGROUND: Stress activates the central nervous, the autonomic nervous, and the endocrine system. This study aimed to (1) test the usability of salivary cortisone in a standardized psychosocial stressor, (2) create a comprehensive profile of hormonal responses to determine laboratory parameters with high discriminatory power, and (3) analyze their association with psychometric and autonomic stress measures. METHODS: Healthy young men (18-35 years) completed either the Trier Social Stress Test (TSST) (n = 33) or a Placebo-TSST (n = 34)...
October 28, 2018: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/30387532/salivary-steroid-hormone-responses-to-dyadic-table-tennis-competitions-among-hong-kongese-juvenile-boys
#3
Timothy S McHale, Peter B Gray, Ka-Chun Chan, David T Zava, Wai-Chi Chee
OBJECTIVES: Little is known about salivary steroid hormone responses to dyadic competition among prepubescent boys. The current study explored pre-match and post-match testosterone, dehydroepiandrosterone (DHEA), androstenedione, and cortisol among 22 ethnically Chinese, Hong Kongese table tennis athletes, aged 8-11 years, during dyadic competition against peers. These data provide novel comparative insight into boys' hormone responses when participating in similar forms of competition to that of adults...
November 2, 2018: American Journal of Human Biology: the Official Journal of the Human Biology Council
https://www.readbyqxmd.com/read/30356364/sarcoidosis-and-monoclonal-gammopathy-of-undetermined-significance-mgus-a-true-association-or-just-a-coincidence
#4
Mohamed Hassanein, Lilit Karapetyan, Afshan Khan, Supratik Rayamajhi
Sarcoidosis is a systemic inflammatory disease characterized by the presence of noncaseating granulomas in different organs. Sarcoidosis associated with monoclonal gammopathy of undetermined significance (MGUS) is a rare finding with only 10 cases reported to date. We describe a 79-year-old male patient who presented with dry mouth for 4 months. Lip biopsy done prior to admission showed nonnecrotizing epithelioid cell granulomas. On admission, laboratory analysis was significant for elevated calcium, decreased parathyroid hormone, increased erythrocyte sedimentation rate, undetectable parathyroid hormone-related peptide (PTHrp), mildly decreased 25-hydroxyvitamin D, elevated 1,25-dihydroxyvitamin D, elevated angiotensin converting enzyme, and positive Bence Jones protein in the urine...
2018: Case Reports in Hematology
https://www.readbyqxmd.com/read/30342884/do-women-s-preferences-for-masculine-voices-shift-across-the-ovulatory-cycle
#5
Julia Jünger, Natalie V Motta-Mena, Rodrigo Cardenas, Drew Bailey, Kevin A Rosenfield, Christoph Schild, Lars Penke, David A Puts
Are estrous mate preference shifts robust? This question is the subject of controversy within human evolutionary sciences. For nearly two decades, mate preference shifts across the ovulatory cycle were considered an important feature of human sexual selection, directing women's attention toward mates with indicators of "good genes" in their fertile phase, when conception is possible. However, several recent studies on masculine faces, bodies and behaviors did not find evidence supporting this account, known as the good genes ovulatory shift hypothesis...
October 20, 2018: Hormones and Behavior
https://www.readbyqxmd.com/read/30337974/the-effect-of-psychological-stress-on-salivary-testosterone-in-puberty-children
#6
Dimas Bagus Prastyo, Melda Deliana, Yazid Dimyati, Karina Sugih Arto
BACKGROUND: Psychological stress is a condition that is experienced by many adolescents which affect the Hypothalamic-Pituitary-Gonadal axis. Testosterone is known as a sex steroid hormone that is susceptible to acute stress and can be measured through saliva. Disruption of the reproductive system can affect the sexual maturation process. AIM: To understand the difference in salivary testosterone levels in puberty children before and after given a stressor. METHODS: A quasi-experimental intervention study was conducted at Antonius Bangun Mulia junior high school, Medan, North Sumatera, in July-October 2017...
September 25, 2018: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/30029405/disposable-electrochemical-immunosensor-for-cortisol-determination-in-human-saliva
#7
Satu Kämäräinen, Marianne Mäki, Tiina Tolonen, Giuseppe Palleschi, Vesa Virtanen, Laura Micheli, Adama Marie Sesay
Cortisol is a steroidal hormone and an important stress marker. Free serum cortisol concentration has been identified to correlate well with free salivary cortisol. In this present work an electrochemical immunosensor was developed to determine cortisol concentration within the physiological concentration range found in human saliva. The immunosensor is based on a direct competitive enzyme linked immunoassay using a home-made cortisol-alkaline phosphatase (AP) conjugate synthesized in our laboratory with disposable graphite screen-printed electrodes (SPEs)...
October 1, 2018: Talanta
https://www.readbyqxmd.com/read/30011910/testosterone-and-cortisol-responses-to-five-high-intensity-functional-training-competition-workouts-in-recreationally-active-adults
#8
Gerald T Mangine, Trisha A Van Dusseldorp, Yuri Feito, Alyssa J Holmes, Paul R Serafini, Allyson G Box, Adam M Gonzalez
To determine the salivary steroid response to high-intensity functional training (HIFT) competition workouts, saliva samples were collected from ten recreationally trained male and female competitors during a 5-week (WK1⁻WK5) international competition. Competitors arrived at their local affiliate and provided samples prior to (PRE) their warm-up, immediately (IP), 30-min (30P), and 60-min (60P) post-exercise. Samples were analyzed for concentrations of testosterone (T), cortisol (C), and their ratio (TC)...
July 14, 2018: Sports
https://www.readbyqxmd.com/read/29948887/steroid-hormone-reactivity-in-fathers-watching-their-children-compete
#9
Louis Calistro Alvarado, Martin N Muller, Melissa A Eaton, Melissa Emery Thompson
This study examines steroid production in fathers watching their children compete, extending previous research of vicarious success or failure on men's hormone levels. Salivary testosterone and cortisol levels were measured in 18 fathers watching their children play in a soccer tournament. Participants completed a survey about the game and provided demographic information. Fathers with higher pregame testosterone levels were more likely to report that referees were biased against their children's teams, and pre- to postgame testosterone elevation was predicted by watching sons compete rather than daughters as well as perceptions of unfair officiating...
September 2018: Human Nature: An Interdisciplinary Biosocial Perspective
https://www.readbyqxmd.com/read/29942016/childhood-ecology-influences-salivary-testosterone-pubertal-age-and-stature-of-bangladeshi-uk-migrant-men
#10
Kesson Magid, Robert T Chatterton, Farid Uddin Ahamed, Gillian R Bentley
Male reproductive investment is energetically costly, and measures of human reproductive steroid hormones (testosterone), developmental tempo (pubertal timing) and growth (stature) correlate with local ecologies at the population level. It is unclear whether male reproductive investment in later life is 'set' during childhood development, mediated through adulthood, or varies by ethnicity. Applying a life-course model to Bangladeshi migrants to the United Kingdom, here we investigate plasticity in human male reproductive function resulting from childhood developmental conditions...
July 2018: Nature Ecology & Evolution
https://www.readbyqxmd.com/read/29909545/coalitional-physical-competition-acute-salivary-steroid-hormone-responses-among-juvenile-male-soccer-players-in-hong-kong
#11
Timothy S McHale, Wai-Chi Chee, Ka-Chun Chan, David T Zava, Peter B Gray
A large body of research links testosterone and cortisol to male-male competition. Yet, little work has explored acute steroid hormone responses to coalitional, physical competition during middle childhood. Here, we investigate testosterone, dehydroepiandrosterone (DHEA), androstenedione, and cortisol release among ethnically Chinese boys in Hong Kong (N = 102), aged 8-11 years, during a soccer match (n = 84) and an intrasquad soccer scrimmage (n = 81), with 63 participants competing in both treatments. The soccer match and intrasquad soccer scrimmage represented out-group and in-group treatments, respectively...
June 16, 2018: Human Nature: An Interdisciplinary Biosocial Perspective
https://www.readbyqxmd.com/read/29894840/slow-wave-sleep-and-androgens-selective-slow-wave-sleep-suppression-affects-testosterone-and-17%C3%AE-hydroxyprogesterone-secretion
#12
Yu V Ukraintseva, K M Liaukovich, А A Polishchuk, О V Martynova, D A Belov, E S Simenel, М Meira E Cruz, А N Nizhnik
OBJECTIVES: Levels of steroid hormones such as androgens and cortisol exhibit circadian variation, and their fluctuations are related to the sleep-wake cycle. Currently, the functional role of different stages of sleep in steroid hormone secretion remains unclear. The present study aims to explore the effect of slow-wave sleep (SWS) suppression on morning levels of cortisol and androgens. METHODS: Twelve healthy male volunteers participated in two experimental sessions: a session with selective SWS suppression during night sleep and a session with regular night sleep (control)...
August 2018: Sleep Medicine
https://www.readbyqxmd.com/read/29887899/comparison-of-salivary-testosterone-levels-in-different-phases-of-bipolar-i-disorder-and-control-group
#13
Sabra Mousavizadegan, Mohsen Maroufi
Background: Testosterone is considered as a primary sex hormone, also known as an important anabolic steroid, that may involve in various mental disorders such as bipolar I disorder (BID). The goal of this study was to compare the testosterone salivary levels between different phases of BID and its association with the clinical features of BID. Materials and Methods: In a case-control study, 15 patients in the mania phase, 10 patients in the depression phase, and 16 in the euthymia phase were selected as patient groups...
2018: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/29875558/comparative-evaluation-of-salivary-cortisol-levels-in-bruxism-patients-before-and-after-using-soft-occlusal-splint-an-in-vivo-study
#14
Pudi Sriharsha, Anil Kumar Gujjari, M R Dhakshaini, Akila Prashant
Introduction: Bruxism is defined as a nonfunctional activity or a parafunctional habit characterized by the unconscious repetitive motion of clenching and/or grinding of the teeth. Soft occlusal splints have been considered as the first-line strategy for treating nocturnal bruxism. Cortisol is a major steroid hormone secreted by fascicular zone of the adrenal cortex, belonging to the glucocorticosteroidal group of hormones. Clinical studies have shown that when humans are placed under stress, the hypothalamic-pituitary-adrenocortical axis is activated, leading to an increase in cortical secretion...
April 2018: Contemporary Clinical Dentistry
https://www.readbyqxmd.com/read/29864660/androgen-disruption-by-dioxin-exposure-in-5-year-old-vietnamese-children-decrease-in-serum-testosterone-level
#15
Nguyen Thi Phuong Oanh, Teruhiko Kido, Seijiro Honma, Yuko Oyama, Le Thai Anh, Hoang Duc Phuc, Nguyen Hoang Viet, Ho Dung Manh, Rie Okamoto, Hideaki Nakagawa, Shoji F Nakayama, Dang Duc Nhu, Dao Van Tung, Vo Van Chi, Nguyen Hung Minh, Ngo Van Toan
Dioxins have been suspected to be potential substances causing endocrine disruptions in humans. We are conducting the research in one of three dioxin exposure areas (hotspots) in Vietnam. We previously reported that the salivary dehydroepiandrosterone (DHEA) level decreased in 3-year-old Vietnamese children and that it was significantly inversely correlated with polychlorinated dibenzodioxin/dibenzofuran levels in their mother's breast milk. In this study, we investigated the influence of exposure to dioxin on steroid hormone biosynthesis in the same children when they reached 5 years of age, focusing on androgens...
November 1, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29864449/testosterone-androstenedione-cortisol-and-cortisone-levels-in-human-unstimulated-stimulated-and-parotid-saliva
#16
Rahel M Büttler, Esra Bagci, Henk S Brand, Martin den Heijer, Marinus A Blankenstein, Annemieke C Heijboer
BACKGROUND: Recently, measurements of steroids like testosterone, androstenedione, cortisol and cortisone in saliva are more and more applied in diagnostics and scientific studies. This is mainly due to the simple and non-invasive collection of saliva. We aimed to evaluate the optimal way to collect saliva for steroid hormone measurement. METHODS: We investigated in twenty volunteers whether there is a difference between steroid hormone concentrations in unstimulated and stimulated saliva collected while chewing, using cotton and synthetic Salivettes®, citric acid or chewing gum...
June 1, 2018: Steroids
https://www.readbyqxmd.com/read/29708849/no-compelling-evidence-that-preferences-for-facial-masculinity-track-changes-in-women-s-hormonal-status
#17
Benedict C Jones, Amanda C Hahn, Claire I Fisher, Hongyi Wang, Michal Kandrik, Chengyang Han, Vanessa Fasolt, Danielle Morrison, Anthony J Lee, Iris J Holzleitner, Kieran J O'Shea, S Craig Roberts, Anthony C Little, Lisa M DeBruine
Although widely cited as strong evidence that sexual selection has shaped human facial-attractiveness judgments, findings suggesting that women's preferences for masculine characteristics in men's faces are related to women's hormonal status are equivocal and controversial. Consequently, we conducted the largest-ever longitudinal study of the hormonal correlates of women's preferences for facial masculinity ( N = 584). Analyses showed no compelling evidence that preferences for facial masculinity were related to changes in women's salivary steroid hormone levels...
June 2018: Psychological Science
https://www.readbyqxmd.com/read/29468906/quantification-of-10-steroid-hormones-in-human-saliva-from-chinese-adult-volunteers
#18
Jian Liu, Xuemei Qiu, Daoming Wang, Yantao Li, Yang Zong, Yichen Liu, Yue Zhang, Ping Yang, Yong Zuo, Huanming Yang, Jian Wang, Yutao Du, Jin Zi
Objective This study was performed to investigate the effects of age and sex on 10 salivary steroid hormones and analyze the correlations between salivary and plasma hormones. Methods The concentrations of 10 salivary steroid hormones in 1090 Chinese adult volunteers were examined using liquid chromatography-tandem mass spectrometry, and a related investigation was performed on the concentrations of salivary hormones in this population. Results The concentrations of androstenedione (A4), 17α-hydroxyprogesterone (17-OHP), aldosterone (ALD), cortisone (COR), corticosterone (CORT), cortisol (F), progesterone (P), and testosterone were significantly different between men and women (Student's t-test)...
April 2018: Journal of International Medical Research
https://www.readbyqxmd.com/read/29332424/salivary-metabolomics-profile-of-patients-with-recurrent-aphthous-ulcer-as-revealed-by-liquid-chromatography-tandem-mass-spectrometry
#19
Yantao Li, Daoming Wang, Chunwei Zeng, Yichen Liu, Guangyuan Huang, Zhanlong Mei
Objective We compared the salivary nontargeted metabolite profiles between patients with recurrent aphthous ulcer (RAU) and healthy individuals to investigate the metabolic alterations associated with RAU. Methods Saliva samples were collected from 45 patients with RAU and 49 healthy individuals, and the salivary metabolites were quantified using liquid chromatography-tandem mass spectrometry. The metabolomic profiles were then analyzed using multivariate and univariate statistical methods, and enrichment of the metabolites in various biological pathways was assessed...
March 2018: Journal of International Medical Research
https://www.readbyqxmd.com/read/29324286/digit-ratio-2d-4d-and-circulating-testosterone-oestradiol-and-progesterone-levels-across-the-menstrual-cycle
#20
Gareth Richards, Magdalena Klimek, Grazyna Jasienska, Urszula M Marcinkowska
BACKGROUND: Digit ratio (2D:4D) is used by researchers as an indicator of prenatal sex hormone exposure. Two previous studies have examined associations between 2D:4D and circulating sex steroid concentrations across the menstrual cycle in adult females. One reported that digit ratio correlated positively with oestradiol levels, whereas the other found no such effect; neither observed significant associations with progesterone. AIMS: To examine associations between 2D:4D, as well as asymmetry (i...
February 2018: Early Human Development
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