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Head and neck cancer children

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https://www.readbyqxmd.com/read/30053755/subtle-excess-in-lifetime-cancer-risk-related-to-ct-scanning-in-spanish-young-people
#1
Magda Bosch de Basea, David Moriña, Jordi Figuerola, Ignasi Barber, Jordi Muchart, Choonsik Lee, Elisabeth Cardis
BACKGROUND: CT scan is a life-saving medical diagnostic tool, entailing higher levels of ionising radiation exposure than conventional radiography, which may result in an increase in cancer risk, particularly in children. Information about the use and potential health effects of CT scan imaging among young people in Spain is scarce. OBJECTIVE: This paper aims to estimate the number of radiation-related cancer cases which can be expected due to the use of CT scanning in Spanish children and young adults in a single year (2013)...
July 24, 2018: Environment International
https://www.readbyqxmd.com/read/29943676/incidence-and-survival-of-thyroid-cancer-in-children-adolescents-and-young-adults-in-denmark-a-nation-wide-study-from-1980-to-2014
#2
Jakob Schmidt Jensen, Christian Grønhøj, Christian Mirian, David Hebbelstrup Jensen, Jeppe Friborg, Christoffer Holst Hahn, Tina Klitmoeller Agander, Thomas Hjuler
BACKGROUND: Thyroid cancer constitutes a major and increasing proportion of head and neck cancers in children and adolescents. The purpose of this study was to determine incidence and survival of thyroid cancer in Danish patients aged 0-24 years from 1980 to 2014. METHODS: We included patients aged 0-24 years registered with primary thyroid cancer in the Danish Cancer Registry or the Danish Pathology Data Bank during 1980-2014. Crude incidence-rates and age-adjusted incidence-rates (AAIR) per 100,000, average annual percent change (AAPC), and overall survival (OS) were evaluated in relation to sex, histopathological tumor type, age at diagnosis, and year of diagnosis...
June 26, 2018: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/29603576/incidence-of-head-and-neck-cancer-in-children-a-danish-nationwide-study-from-1978-to-2014
#3
Christian Grønhøj, Lisa Hjalgrim, Kathrine K Jakobsen, Birgitte Charabi, Christian Mirian, Gunnar H Laier, Katalin Kiss, Catherine Rechnitzer, Jeppe Friborg, Christian von Buchwald, Thomas Hjuler
BACKGROUND: Pediatric head and neck malignancies are rare and only a few descriptive epidemiological studies have been published. Using unique nationwide registries, we report age-specific incidence rates of head and neck cancer (HNC) among children during four decades. METHODS: Data were obtained from the Danish Cancer Registry. We included children aged 0-14 years diagnosed between January 1, 1978 and December 31, 2014 with extra-orbital, nonskin and nonbone HNC...
July 2018: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/29602585/trend-in-otolaryngological-surgeries-in-an-era-of-super-aging-descriptive-statistics-using-a-japanese-inpatient-database
#4
Sayaka Suzuki, Hideo Yasunaga, Hiroki Matsui, Kiyohide Fushimi, Tatsuya Yamasoba
OBJECTIVE: To reveal the age distribution and capture the longitudinal trend in otolaryngological surgeries performed in Japan, where society is rapidly aging. METHODS: Using the Diagnosis Procedure Combination database, we extracted data on patients who were hospitalized and underwent any type of otolaryngological surgery in departments of otolaryngology or head and neck surgery from fiscal year 2007 to fiscal year 2013. Type of surgery, patient's age, and fiscal year were compared...
March 27, 2018: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/29541566/surgical-interventions-for-advanced-parameningeal-rhabdomyosarcoma-of-children-and-adolescents
#5
REVIEW
Paul J Choi, Joe Iwanaga, R Shane Tubbs, Emre Yilmaz
Owing to its rarity, rhabdomyosarcoma of the head and neck (HNRMS) has seldom been discussed in the literature. As most of the data is based only on the retrospective experiences of tertiary healthcare centers, there are difficulties in formulating a standard treatment protocol. Moreover, the disease is poorly understood at its pathological, genetic, and molecular levels. For instance, 20% of all histological assessment is inaccurate; even an experienced pathologist can confuse rhabdomyosarcoma (RMS) with neuroblastoma, Ewing's sarcoma, and lymphoma...
January 9, 2018: Curēus
https://www.readbyqxmd.com/read/29513872/prevalence-of-communication-swallowing-and-orofacial-myofunctional-disorders-in-children-and-adolescents-at-the-time-of-admission-at-a-cancer-hospital
#6
Kaliani Lima Coça, Anke Bergmann, Sima Ferman, Elisabete Carrara de Angelis, Márcia Gonçalves Ribeiro
PURPOSE: Describe the prevalence of communication, swallowing and orofacial myofunctional disorders in a group of children and adolescents at the time of registration at a cancer hospital. METHODS: A cross-sectional study conducted with children aged ≥2 and adolescents, of both genders, admitted to the Pediatric Oncology Section of the Instituto Nacional de Câncer José de Alencar Gomes da Silva (INCA) from March 2014 to April 2015 for investigation and/or treatment of solid tumors...
March 1, 2018: CoDAS
https://www.readbyqxmd.com/read/29509716/risk-factors-including-age-stage-and-anatomic-location-that-impact-the-outcomes-of-patients-with-synovial-sarcoma
#7
Minggui Pan, Maqdooda Merchant
Synovial sarcoma is a high-grade soft tissue sarcoma that inflicts mostly children and young adults with high mortality rate; however, the risk factors that impact the outcomes remain incompletely understood. We have identified the synovial sarcoma cases from the Kaiser Permanente Northern California cancer registry between 1981 and 2014. Kaplan-Meier plots were used to display disease-free survival (DFS) and overall survival (OS); log-rank tests and Cox proportional hazard models were used to determine the impact of clinical factors on DFS, OS, and disease-specific survival...
March 6, 2018: Medical Sciences: Open Access Journal
https://www.readbyqxmd.com/read/29461635/clinical-and-mutational-spectrum-of-highly-differentiated-paired-box-3-forkhead-box-protein-o1-fusion-negative-rhabdomyosarcoma-a-report-from-the-children-s-oncology-group
#8
Lisa A Teot, Michaela Schneider, Aaron R Thorner, Jing Tian, Yueh-Yun Chi, Matthew Ducar, Ling Lin, Marcin Wlodarski, Holcombe E Grier, Christopher D M Fletcher, Paul van Hummelen, Stephen X Skapek, Douglas S Hawkins, Amy J Wagers, Carlos Rodriguez-Galindo, Simone Hettmer
BACKGROUND: Pediatric paired box 3:forkhead box protein O1 fusion-negative (PF-) rhabdomyosarcoma (RMS) represents a diverse spectrum of tumors with marked differences in histology, myogenic differentiation, and clinical behavior. METHODS: This study sought to evaluate the clinical and mutational spectrum of 24 pediatric PF- human RMS tumors with high levels of myogenic differentiation. Tumors were sequenced with OncoPanel v.2, a panel consisting of the coding regions of 504 genes previously linked to human cancer...
May 1, 2018: Cancer
https://www.readbyqxmd.com/read/29234851/correction-to-fdg-uptake-in-cervical-lymph-nodes-in-children-without-head-and-neck-cancer
#9
Reza Vali, Alaa Bakkari, Eman Marie, Mahnaz Kousha, Martin Charron, Amer Shammas
The original version of this article unfortunately contained a mistake. Author name Alaa Bakkari was incorrect. The correct spelling is given above.
March 2018: Pediatric Radiology
https://www.readbyqxmd.com/read/29199473/sun-protection-among-new-zealand-primary-school-children
#10
Ryan Gage, William Leung, James Stanley, Anthony Reeder, Christina Mackay, Moira Smith, Michelle Barr, Tim Chambers, Louise Signal
Schools are an important setting for raising skin cancer prevention awareness and encouraging sun protection. We assessed the clothes worn and shade used by 1,278 children in eight schools in the Wellington region of New Zealand. These children were photographed for the Kids'Cam project between September 2014 and March 2015 during school lunch breaks. Children's mean clothing coverage (expressed as a percentage of body area covered) was calculated. Data on school sun-safety policies were obtained via telephone...
December 1, 2017: Health Education & Behavior: the Official Publication of the Society for Public Health Education
https://www.readbyqxmd.com/read/29181845/interventions-for-preventing-oral-mucositis-in-patients-with-cancer-receiving-treatment-cytokines-and-growth-factors
#11
REVIEW
Philip Riley, Anne-Marie Glenny, Helen V Worthington, Anne Littlewood, Luisa M Fernandez Mauleffinch, Jan E Clarkson, Martin G McCabe
BACKGROUND: Oral mucositis is a side effect of chemotherapy, head and neck radiotherapy, and targeted therapy, affecting over 75% of high-risk patients. Ulceration can lead to severe pain and difficulty with eating and drinking, which may necessitate opioid analgesics, hospitalisation and supplemental nutrition. These complications may disrupt cancer therapy, which may reduce survival. There is also a risk of death from sepsis if pathogens enter the ulcers of immunocompromised patients...
November 28, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28891406/clinical-practice-guideline-evaluation-of-the-neck-mass-in-adults
#12
Melissa A Pynnonen, M Boyd Gillespie, Benjamin Roman, Richard M Rosenfeld, David E Tunkel, Laura Bontempo, Itzhak Brook, Davoren Ann Chick, Maria Colandrea, Sandra A Finestone, Jason C Fowler, Christopher C Griffith, Zeb Henson, Corinna Levine, Vikas Mehta, Andrew Salama, Joseph Scharpf, Deborah R Shatzkes, Wendy B Stern, Jay S Youngerman, Maureen D Corrigan
Objective Neck masses are common in adults, but often the underlying etiology is not easily identifiable. While infections cause most of the neck masses in children, most persistent neck masses in adults are neoplasms. Malignant neoplasms far exceed any other etiology of adult neck mass. Importantly, an asymptomatic neck mass may be the initial or only clinically apparent manifestation of head and neck cancer, such as squamous cell carcinoma (HNSCC), lymphoma, thyroid, or salivary gland cancer. Evidence suggests that a neck mass in the adult patient should be considered malignant until proven otherwise...
September 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28814368/uncommon-occurrence-of-lip-squamous-cell-carcinoma-in-a-pediatric-patient
#13
Saygo Tomo, Ingrid da Silva Santos, Aline Reis Stefanini, Guilherme de Oliveira Cucolicchio, Glauco Issamu Miyahara, Luciana Estevam Simonato
Although head and neck squamous cell carcinoma represents one of the most common cancers among adults, it is rare in pediatric patients. The purpose of this report is to discuss the case of a 15-year-old male patient referred by his dentist due to a three-month old ulcer in his lower lip. The patient denied tobacco smoking and drinking alcohol, and confirmed that he performed manual labor in a brick yard, being exposed daily to the sun without protection. Clinical examination revealed an exophytic rounded ulcer in the right lower lip, measuring 1...
May 15, 2017: Journal of Dentistry for Children
https://www.readbyqxmd.com/read/28798906/cerebral-sinovenous-thrombosis
#14
REVIEW
Rebecca Ichord
Cerebral sinovenous thrombosis (CSVT) is a rare but serious cerebrovascular disorder affecting children from the newborn period through childhood and adolescence. The incidence is estimated at 0.6/100,000/year, with 30-50% occurring in newborns. Causes are diverse and are highly age dependent. Acute systemic illness is the dominant risk factor among newborns. In childhood CSVT, acute infections of the head and neck such as mastoiditis are most common, followed by chronic underlying diseases such as nephrotic syndrome, cancer, and inflammatory bowel disease...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28695786/antibiotic-prophylaxis-in-clean-contaminated-head-and-neck-surgery-a-systematic-review-and-meta-analysis
#15
REVIEW
Peter M Vila, Joseph Zenga, Ryan S Jackson
Objective To determine the optimal duration and type of antibiotic prophylaxis in patients undergoing clean-contaminated resection for head and neck cancer. Data Sources Search strategies were created by a medical librarian, implemented in multiple databases, and completed in June 2016. Review Methods The population of interest was adults ≥18 years undergoing clean-contaminated head and neck surgery, intervention was postoperative antibiotic prophylaxis, comparator was duration and types of antibiotics used, outcome was the wound infection rate, and the study design was randomized controlled trials (RCTs)...
October 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28654202/socioeconomic-factors-affect-the-selection-of-proton-radiation-therapy-for-children
#16
Colette J Shen, Chen Hu, Matthew M Ladra, Amol K Narang, Craig E Pollack, Stephanie A Terezakis
BACKGROUND: Proton radiotherapy remains a limited resource despite its clear potential for reducing radiation doses to normal tissues and late effects in children in comparison with photon therapy. This study examined the impact of race and socioeconomic factors on the use of proton therapy in children with solid malignancies. METHODS: This study evaluated 12,101 children (age ≤ 21 years) in the National Cancer Data Base who had been diagnosed with a solid malignancy between 2004 and 2013 and had received photon- or proton-based radiotherapy...
October 15, 2017: Cancer
https://www.readbyqxmd.com/read/28643357/nut-carcinoma-in-children-and-adults-a-multicenter-retrospective-study
#17
MULTICENTER STUDY
Lauriane Lemelle, Gaëlle Pierron, Paul Fréneaux, Sophie Huybrechts, Alexandra Spiegel, Dominique Plantaz, Morbize Julieron, Sophie Dumoucel, Antoine Italiano, Fréderic Millot, Christophe Le Tourneau, Guy Leverger, Pascal Chastagner, Matthieu Carton, Daniel Orbach
BACKGROUND: Nuclear protein of the testis (NUT) carcinoma (formerly NUT midline carcinoma) is an aggressive tumor defined by the presence of NUT rearrangement with a poor prognosis. This rare cancer is underdiagnosed and poorly treated. OBJECTIVE: The primary objective of this study was to describe the clinical, radiologic, and biological features of NUT carcinoma. The secondary objective was to describe the various treatments and assess their efficacy. METHODS: This retrospective multicenter study was based on review of the medical records of children and adults with NUT carcinoma with specific rearrangement or positive anti-NUT nuclear staining (>50%)...
December 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28530060/-the-truth-about-the-ringworm-affair
#18
REVIEW
Aya Bar Oz
Ringworm of the scalp (Tinea Capitis), a fungal skin ailment that appears on the scalp, was treated until the early sixties by radiation therapy. It was discovered during the seventies that radiation treatment for ringworm may be associated with a higher risk of cancerous and benign tumors in the head and neck area for patients undergoing treatment. In 1995, Israel enacted a law to compensate ringworm irradiation patients which provided monetary compensation for those who were treated between 1946 and 1960...
October 2016: Harefuah
https://www.readbyqxmd.com/read/28357549/fdg-uptake-in-cervical-lymph-nodes-in-children-without-head-and-neck-cancer
#19
Reza Vali, Alaa Bakkari, Eman Marie, Mahnaz Kousha, Martin Charron, Amer Shammas
BACKGROUND: Reactive cervical lymphadenopathy is common in children and may demonstrate increased 18 F-fluoro-deoxyglucose (18 F-FDG) uptake on positron emission tomography/computed tomography (PET/CT). OBJECTIVE: We sought to evaluate the frequency and significance of 18 F-FDG uptake by neck lymph nodes in children with no history of head and neck cancer. MATERIALS AND METHODS: The charts of 244 patients (114 female, mean age: 10.4 years) with a variety of tumors such as lymphoma and post-transplant lymphoproliferative diseases (PTLD), but no head and neck cancers, who had undergone 18 F-FDG PET/CT were reviewed retrospectively...
June 2017: Pediatric Radiology
https://www.readbyqxmd.com/read/28170129/survey-of-return-to-work-of-head-and-neck-cancer-survivors-a-report-from-a-tertiary-cancer-center-in-india
#20
Jaiprakash Agarwal, Rahul Krishnatry, Pankaj Chaturvedi, Sarbani Ghosh-Laskar, Tejpal Gupta, Ashwani Budrukkar, Vedang Murthy, Joyita Deodhar, Deepa Nair, Sudhir Nair, Rajesh Dikshit, Anil K D'Cruz
BACKGROUND: The rates and factors associated with the return to work of head and neck cancer survivors from low- and middle-income countries, such as India, are largely unknown. METHODS: We conducted a preliminary cross-sectional survey of 250 consecutive eligible head and neck cancer survivors (age <60; ≥6 months posttreatment) to identify return to work rates and sociodemographic, clinical, and quality of life (QOL; European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30-questions [EORTC-QLQ-C30] and European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 Head and Neck 35-questions [EORTC-QLQ-H&N35]) correlates...
May 2017: Head & Neck
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