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https://www.readbyqxmd.com/read/30340837/gait-and-balance-one-year-after-stroke-relationships-with-lesion-side-subtypes-of-cognitive-impairment-and-neuroimaging-findings-a-longitudinal-cohort-study
#1
Marie Helene Ursin, Astrid Bergland, Brynjar Fure, Bente Thommessen, Guri Hagberg, Anne Rita Øksengård, Hege Ihle-Hansen
OBJECTIVES: The aims of this study are to investigate impairments of balance and gait in various types of dementia and cognitive impairment, and neuroimaging correlates in patients one year after first-ever stroke or transient ischemic attack. DESIGN: This is a longitudinal cohort study. PARTICIPANTS: 180 participants were included and a total of 156 participated in the assessments at the one-year follow-up. MAIN OUTCOME MEASURES: Measurements of balance and gait comprised the Berg Balance Scale (BBS) and the 10meter walk test (10MWT)...
August 3, 2018: Physiotherapy
https://www.readbyqxmd.com/read/30340088/idiopathic-normal-pressure-hydrocephalus-and-obstructive-sleep-apnea-are-frequently-associated-a-prospective-cohort-study
#2
Gustavo C Román, Aparajitha K Verma, Y Jonathan Zhang, Steve H Fung
BACKGROUND: Idiopathic normal-pressure hydrocephalus (iNPH) is defined by ventriculomegaly, cognitive decline, urinary incontinence and gait problems. Vascular risk factors (VRF) are associated with iNPH but obstructive sleep apnea (OSA) -a well-known independent VRF- is seldom mentioned. METHODS: We investigated the presence of sleep-disordered breathing in a prospective cohort of 31 consecutive unselected patients with iNPH using sleep questionnaires and nocturnal polysomnography (PSG)...
October 3, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/30338813/research-on-changes-in-cognitive-function-%C3%AE-amyloid-peptide-and-neurotrophic-factor-in-stroke-patients
#3
H-G Chen, M Wang, A-H Jiao, G-T Tang, W Zhu, P Zou, T Li, G-Q Cui, P-Y Gong
OBJECTIVE: To investigate the changes as well as the related mechanism in cognitive function and levels of serum β-amyloid peptide (Aβ) and brain-derived neurotrophic factor (BDNF) in stroke patients. PATIENTS AND METHODS: A total of 30 patients with acute stroke treated in our hospital from June 2015 to September 2016 were selected as stroke group, while 30 volunteers during the same period were enrolled as control group. Changes in cognitive function of patients were evaluated using the Montreal Cognitive Assessment (MoCA) and mini-mental state examination (MMSE) before and after the treatment...
October 2018: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/30338749/daily-living-activities-and-cognition-in-aged-patients-effect-of-acute-systemic-diseases-and-stroke-on-leukoaraiosis
#4
Raul O Dominguez, Enrique R Marschoff, Liliana M Oudkerk, Luis J Neira, Jorge A Serra
BACKGROUND: Acute systemic diseases (ASD) impact in extended leukoaraiosis (ExL-A) have been seldom described. We study the deterioration in daily life activities (DLA) and cognition associated with ASD events compared with the well described impacts of stroke in patients with leukoaraiosis (L-A). METHODS: Cross-sectional surveys of aged adults from the emergency room after an acute event of ASD or stroke, hospitalized or receiving home care, were followed for one year...
October 18, 2018: Current Aging Science
https://www.readbyqxmd.com/read/30337124/the-cooking-therapy-for-cognitive-rehabilitation-of-cerebellar-damage-a-case-report-and-a-review-of-the-literature
#5
Antonio Cerasa, Francesco Arcuri, Luigina Maria Pignataro, Sebastiano Serra, Demetrio Messina, Simone Carozzo, Antonio Biafora, Caterina Ceraudo, Luca Abbruzzino, Loris Pignolo, Giuseppina Basta, Paolo Tonin
BACKGROUND AND IMPORTANCE: The therapeutic approach for cerebellar damages heavily relies on neurorehabilitation since there are no medications that may improve clinical symptoms mainly those related to cognitive dysfunctions. Nevertheless, neurorehabilitation programs tailored to cerebellar damages have never been validated. Here we describe a new rehabilitation approach based on cooking training (CT). The idea that cooking may stimulate cerebellar activity relies on previous evidence demonstrating the beneficial effect on the executive functions as well as in promoting neural plasticity within the cerebellum...
October 15, 2018: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/30336478/beam-walking-to-assess-dynamic-balance-in-health-and-disease-a-protocol-for-the-beam-multicenter-observational-study
#6
Tibor Hortobágyi, Azusa Uematsu, Lianne Sanders, Reinhold Kliegl, József Tollár, Renato Moraes, Urs Granacher
BACKGROUND: Dynamic balance keeps the vertical projection of the center of mass within the base of support while walking. Dynamic balance tests are used to predict the risks of falls and eventual falls. The psychometric properties of most dynamic balance tests are unsatisfactory and do not comprise an actual loss of balance while walking. OBJECTIVES: Using beam walking distance as a measure of dynamic balance, the BEAM consortium will determine the psychometric properties, lifespan and patient reference values, the relationship with selected "dynamic balance tests," and the accuracy of beam walking distance to predict falls...
October 18, 2018: Gerontology
https://www.readbyqxmd.com/read/30336136/the-neuroprotective-effect-of-lithium-chloride-on-cognitive-impairment-through-glycogen-synthase-kinase-3%C3%AE-inhibition-in-intracerebral-hemorrhage-rats
#7
Zhen Liu, Rui Li, Cheng Jiang, Sha Zhao, Weishan Li, Xiaobo Tang
To the clinical cognitive impairment following intracerebral hemorrhage, comprehensive neuropsychological assessments and efficacious interventions have rarely been conducted. Lithium chloride, a classical treatment for bipolar disorder, has shown neuroprotective effects through glycogen synthase kinase-3β inhibition in a variety of central nervous system diseases, including stroke. Since neurons that contain glutamate play crucial roles in psychological functions, such as learning and memory, the glutamate-mediated excitotoxicity and consequent neuronal death and cognitive impairment in hippocampus may co-determine the clinical course of intracerebral hemorrhage...
October 15, 2018: European Journal of Pharmacology
https://www.readbyqxmd.com/read/30334864/unique-stroke-symptoms-in-women-a-review
#8
Renee Colsch, Glenda Lindseth
BACKGROUND: Research suggests that there is a delay in recognizing unique stroke symptoms in women by both healthcare professionals and the general population. The purpose of this review was to identify and summarize the most relevant literature regarding recognition and assessment of unique stroke symptoms in women. METHODS: Literature review using PubMed, CINAHL, ERIC, MEDLINE, PsycINFO, and Google Scholar was used to search literature describing unique stroke symptoms...
October 16, 2018: Journal of Neuroscience Nursing: Journal of the American Association of Neuroscience Nurses
https://www.readbyqxmd.com/read/30333160/who-should-undergo-a-comprehensive-cognitive-assessment-after-a-stroke-a-cognitive-risk-score
#9
Olivier Godefroy, Hugo Yaïche, Hervé Taillia, Flavie Bompaire, Claudine Nédélec-Ciceri, Camille Bonnin, Jérôme Varvat, Françoise Vincent-Grangette, Momar Diouf, Jean-Louis Mas, Sandrine Canaple, Chantal Lamy, Audrey Arnoux, Claire Leclercq, Sophie Tasseel-Ponche, Martine Roussel, Mélanie Barbay
OBJECTIVE: To validate the ability of a specifically developed cognitive risk score to identify patients at risk of poststroke neurocognitive disorders (NCDs) who are eligible for a comprehensive cognitive assessment. METHODS: After assessing 404 patients (infarct 91.3%) in the Groupe de Réflexion pour l'Evaluation Cognitive VASCulaire (GRECogVASC) cross-sectional study with the National Institute of Neurological Disorders and Stroke-Canadian Stroke Network battery 6 months after stroke, we used multivariable logistic regression and bootstrap analyses to determine factors associated with NCDs...
October 17, 2018: Neurology
https://www.readbyqxmd.com/read/30333158/early-moca-predicts-long-term-cognitive-and-functional-outcome-and-mortality-after-stroke
#10
Vera Zietemann, Marios K Georgakis, Thibaut Dondaine, Claudia Müller, Anne-Marie Mendyk, Anna Kopczak, Hilde Hénon, Stéphanie Bombois, Frank Arne Wollenweber, Régis Bordet, Martin Dichgans
OBJECTIVE: To examine whether the Montreal Cognitive Assessment (MoCA) administered within 7 days after stroke predicts long-term cognitive impairment, functional impairment, and mortality. METHODS: MoCA was administered to 274 patients from 2 prospective hospital-based cohort studies in Germany (n = 125) and France (n = 149). Cognitive and functional outcomes were assessed at 6, 12, and 36 months after stroke by comprehensive neuropsychological testing, the Clinical Dementia Rating (CDR) scale, the modified Rankin Scale (mRS), and Instrumental Activities of Daily Living (IADL) and analyzed with generalized estimating equations...
October 17, 2018: Neurology
https://www.readbyqxmd.com/read/30333009/neurovascular-dysfunction-in-vascular-dementia-alzheimer-s-and-atherosclerosis
#11
REVIEW
Osman Shabir, Jason Berwick, Sheila E Francis
Efficient blood supply to the brain is of paramount importance to its normal functioning and improper blood flow can result in potentially devastating neurological consequences. Cerebral blood flow in response to neural activity is intrinsically regulated by a complex interplay between various cell types within the brain in a relationship termed neurovascular coupling. The breakdown of neurovascular coupling is evident across a wide variety of both neurological and psychiatric disorders including Alzheimer's disease...
October 17, 2018: BMC Neuroscience
https://www.readbyqxmd.com/read/30332331/neuroscience-and-greek-mythology
#12
Ioannis Karakis
This article highlights the major reflections of ancient Greek mythology in modern neuroscience. An analysis of ancient Greek texts and medical literature using the MeSH term mythology was performed to identify mythological references pertaining to neuroscience. The findings are discussed in relation to etymology, early conceptualization of the nervous system structure and function, incipient characterization of neuropsychiatric disease, and philosophical stance to the practice of medicine in ancient Greece...
October 17, 2018: Journal of the History of the Neurosciences
https://www.readbyqxmd.com/read/30328803/implementing-the-proclamation-of-stroke-and-potentially-preventable-dementias
#13
Vladimir Hachinski, Detlev Ganten, Daniel Lackland, Reinhold Kreutz, Konstantinos Tsioufis, Werner Hacke
Brain health plays a central role in wellbeing and in the management of chronic diseases. Stroke and dementia pose the two greatest threats to brain health, but recent developments suggest the possibility that preventing stroke may also prevent some dementias: 1. A large population study showed a 32% decrease in the incidence of stroke and a concomitant 7% reduction in the incidence of dementia; 2. Treatment of atrial fibrillation resulted not only in stroke reduction, but a 48% decrease in dementia; 3. A hypothesis free analyses has shown that the first phase of Alzheimer disease involves vascular dysregulation, opening the door to new therapeutic approaches; 4...
October 2018: International Journal of Stroke: Official Journal of the International Stroke Society
https://www.readbyqxmd.com/read/30327218/impact-of-small-vessel-disease-on-severity-of-motor-and-cognitive-impairment-in-parkinson-s-disease
#14
Raymond S Schwartz, Glenda M Halliday, Derrick Soh, Dennis J Cordato, Jillian J Kril
BACKGROUND: Subcortical small vessel disease and vascular risk factors are associated with motor and cognitive impairment. In this study we examined the relationship between these factors and the severity of motor impairment and dementia in pathologically-confirmed Parkinson's disease (PD). METHODS: The extent and severity of small vessel disease (SVD) was assessed pathologically in 77 patients with PD. The severity of motor impairment was determined using a cumulative index derived from longitudinal measures of Hoehn and Yahr score...
October 13, 2018: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/30323946/evaluation-of-a-smartwatch-based-intervention-providing-feedback-of-daily-activity-within-a-research-naive-stroke-ward-a-pilot-randomised-controlled-trial
#15
Sophie Lawrie, Yun Dong, Dax Steins, Zhidao Xia, Patrick Esser, Shanbin Sun, Fei Li, James D Amor, Christopher James, Hooshang Izadi, Yi Cao, Derick Wade, Nancy Mayo, Helen Dawes
Background: The majority of stroke patients are inactive outside formal therapy sessions. Tailored activity feedback via a smartwatch has the potential to increase inpatient activity. The aim of the study was to identify the challenges and support needed by ward staff and researchers and to examine the feasibility of conducting a randomised controlled trial (RCT) using smartwatch activity monitors in research-naive rehabilitation wards. Objectives (Phase 1 and 2) were to report any challenges and support needed and determine the recruitment and retention rate, completion of outcome measures, smartwatch adherence rate, (Phase 2 only) readiness to randomise, adherence to protocol (intervention fidelity) and potential for effect...
2018: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/30322425/correlates-of-sedentary-behavior-in-middle-aged-and-old-age-people-with-mild-cognitive-impairment-a-multinational-study
#16
Davy Vancampfort, Brendon Stubbs, Elvira Lara, Mathieu Vandenbulcke, Nathalie Swinnen, Ai Koyanagi
OBJECTIVE: Despite the benefits of being active for people with mild cognitive impairment (MCI) on cognition and the acknowledgement that MCI is a critical period for intervening to prevent dementia, little is known about the actual sedentary levels in people with MCI. This study investigates correlates of sedentary behavior (SB) in people with MCI. DESIGN: This was a cross-sectional study. SETTING: Data from the World Health Organization's Study on Global Ageing and Adult Health were analyzed...
October 16, 2018: International Psychogeriatrics
https://www.readbyqxmd.com/read/30322404/the-association-between-blood-pressure-variability-bpv-with-dementia-and-cognitive-function-a-systematic-review-and-meta-analysis-protocol
#17
(no author information available yet)
BACKGROUND: A body of empirical work demonstrates that wide fluctuations in a person's blood pressure across consecutive measures, known as blood pressure variability (BPV), hold prognostic value to predict stroke and transient ischemic attack. However, the magnitude of association between BPV and other neurological outcomes remains less clear. This systematic review aims to pool together data regarding BPV with respect to incident dementia, cognitive impairment, and cognitive function...
October 15, 2018: Systematic Reviews
https://www.readbyqxmd.com/read/30321060/predictors-of-cognitive-and-academic-outcome-following-childhood-subcortical-stroke
#18
Robyn Westmacott, Kyla P McDonald, Samantha D Roberts, Gabrielle deVeber, Daune MacGregor, Mahendranath Moharir, Nomazulu Dlamini, Tricia S Williams
Childhood arterial ischemic stroke often involves basal ganglia and thalamus but little is known about neuropsychological outcomes in this group. We examined intellectual ability, academics, attention, executive function, and psychological diagnoses in children and adolescents (6-20 years of age) with childhood stroke involving the basal ganglia (n = 32) or thalamus (n = 12). Intellectual ability was age-appropriate but working memory was significantly lower than expected. Compared to the normative mean, the stroke group exhibited significantly weaker performance in reading comprehension, math fluency, attention, and greater challenges with executive function...
October 15, 2018: Developmental Neuropsychology
https://www.readbyqxmd.com/read/30321040/the-russian-version-of-the-oxford-cognitive-screen-validation-study-on-stroke-survivors
#19
Maria Shendyapina, Ekaterina Kuzmina, Sergey Kazymaev, Anna Petrova, Nele Demeyere, Brendan S Weekes
OBJECTIVE: The Oxford Cognitive Screen (OCS) is a screening tool for the assessment of poststroke deficits in attention, memory, praxis, language, and number processing. The goal of the present study was to develop a Russian version of the OCS (Rus-OCS) via translation of the original battery, its cultural and linguistic adaptations, and reporting preliminary findings on its psychometric properties. METHOD: All parts of OCS were translated by native Russian-speaking neuropsychologists...
October 15, 2018: Neuropsychology
https://www.readbyqxmd.com/read/30319530/vagus-nerve-stimulation-attenuates-cerebral-microinfarct-and-colitis-induced-cerebral-microinfarct-aggravation-in-mice
#20
Xiaofeng Chen, Xiaofei He, Shijian Luo, Yukun Feng, Fengyin Liang, Taotao Shi, Ruxun Huang, Zhong Pei, Zhendong Li
Cerebral cortical microinfarct (CMI) is common in patients with dementia and cognitive decline. Emerging studies reported that intestinal dysfunction influenced the outcome of ischemic stroke and that vagus nerve stimulation (VNS) protected against ischemic stroke. However, the effects of intestinal dysfunction and VNS on CMI are not clear. Therefore, we examined the influence of colitis and VNS on CMI and the mechanisms of VNS attenuating CMI in mice with colitis. CMI was induced using a two-photon laser. Colitis was induced using oral dextran sodium sulfate (DSS)...
2018: Frontiers in Neurology
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