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Implantable loop recorder

R S S Kort, Y S Tuininga, H A Bosker, M Janssen, R Tukkie
INTRODUCTION: In the care of heart failure patients, telemonitoring is receiving growing attention. The main purpose of this study was to determine the effect of continuous telemonitoring with an implantable loop recorder (ILR, Reveal XT), a novel strategy in the management of stable heart failure patients without a cardiac implantable device. Furthermore, little is known about the incidence of subclinical arrhythmias in this specific group of patients. MATERIALS AND METHODS: Stable heart failure patients, New York Heart Association Class II and III, without recent hospitalisation or upcoming intervention, were included...
December 3, 2018: Netherlands Heart Journal
Massimo Santini, Luca Santini, Stefania A Di Fusco
A very fast-paced improvement of technology in the field of cardiac implantable devices has been observed in the last ten years. The aim of this review is to highlight the most important innovations which have been recently introduced in this field, such as the leadless pacemaker (a heart stimulator without intracardiac leads), the subcutaneous defibrillator (a completely extracardiac defibrillator device), the injectable loop recorder (a miniaturized subcutaneous continuous echocardiographic monitor provided by alarms and telephonic transmission) and many other new devices which will completely change the clinical practice in this field over the next decade...
December 2018: Minerva Cardioangiologica
Jonathan Massachi, Yi-Kai Lo, Po-Min Wang, Wentai Liu
The efficacy of many clinical applications of electrical stimulation is currently gauged only by patients' verbal feedback or through the use of an independent system, limiting physicians' ability to provide quality treatment. By integrating neural response recording into the system, though, more accurate measures of treatment effectiveness are possible. This paper presents a platform which enables wireless control of an implantable bioelectronic device which integrates functional electrical stimulation and simultaneous recording of neural activity for a wide range of potential applications including motor function prostheses for spinal cord injury, retinal prostheses, and treatments for various other conditions...
July 2018: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Syed A Shah, Gerd Tinkhauser, Chiung Chu Chen, Simon Little, Peter Brown
Deep Brain Stimulation (DBS) is a widely used therapy to ameliorate symptoms experienced by patients with Parkinson's Disease (PD). Conventional DBS is continuously ON even though PD symptoms fluctuate over time leading to undesirable side-effects and high energy requirements. This study investigates the use of a Iogistic regression-based classifier to identify periods when PD patients have rest tremor exploiting Local Field Potentials (LFPs) recorded with DBS electrodes implanted in the Subthalamic Nucleus in 7 PD patients (8 hemispheres)...
July 2018: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Thomas Tarnaud, Emmeric Tanghe, Sebastian Haesler, Carolina Mora Lopez, Luc Martens, Wout Joseph
Deep brain stimulation is an established surgical treatment for several neurological and movement disorders, such as Parkinson's disease, in which electrostimulation is applied to targeted deep nuclei in the basal ganglia through implanted electrode leads. Recent technological improvements in the field have focused on the theoretical advantage of current steering and adaptive (closed-loop) deep brain stimulation. Current steering between several active electrodes would allow for improved accuracy when targeting the desired brain structures...
July 2018: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Fazilet Dede, Sabriye Karadenizli, Ozgur Doga Ozsoy, Fatma Ceyla Eraldemir, Deniz Sahin, Nurbay Ates
Epilepsy is a major pathological condition, characterized by recurrent seizures and affecting approximately 1% of the population. Many studies have shown a relationship between epilepsy and inflammation. The adenosinergic system contributes to inflammation and epilepsy by regulating the release of neurotransmitters through its various receptors. This study investigates the effect of agonist and antagonist of adenosinergic system on seizure activity and cytokine levels in the WAG/Rij strain, a genetic animal model of absence epilepsy...
November 7, 2018: Journal of Neuroimmunology
Flavia Vitale, Wendy Shen, Nicolette Driscoll, Justin C Burrell, Andrew G Richardson, Oladayo Adewole, Brendan Murphy, Akshay Ananthakrishnan, Hanju Oh, Theodore Wang, Timothy H Lucas, D Kacy Cullen, Mark G Allen, Brian Litt
Intracranial electrodes are a vital component of implantable neurodevices, both for acute diagnostics and chronic treatment with open and closed-loop neuromodulation. Their performance is hampered by acute implantation trauma and chronic inflammation in response to implanted materials and mechanical mismatch between stiff synthetic electrodes and pulsating, natural soft host neural tissue. Flexible electronics based on thin polymer films patterned with microscale conductive features can help alleviate the mechanically induced trauma; however, this strategy alone does not mitigate inflammation at the device-tissue interface...
2018: PloS One
Bhaskar Bhardwaj, Senthil A Kumar, Richard Webel, Sandeep Gautam, Anand Chockalingam
Left ventricular diverticula (LVD) are rare congenital anomalies usually detected incidentally in the adult population. Most commonly, they are found as a single left ventricular diverticulum in association with other congenital abnormalities but multiple LVD are exceedingly rare. We are describing a patient who was found to have multiple LVD on multimodality imaging studies. He had presented with a sudden cardiac arrest attributed to a combination of alcohol intoxication and QT interval prolongation from hypokalemia and antidepressant medications...
October 30, 2018: Echocardiography
Seung Woo Lee, Krishnan Thyagarajan, Shelley Fried
OBJECTIVE: Electrical stimulation via cortically- implanted electrodes has been proposed to treat a wide range of neurological disorders. Effectiveness has been limited, however, in part due to the inability of conventional electrodes to activate specific types of neurons while avoiding other types. Recent demonstrations that magnetic stimulation from a micro-coil can selectively activate pyramidal neurons (PNs) while avoiding passing axons suggest the possibility that such an approach can overcome some this limitation and here we use computer simulations to explore how the micro-coil design influences the selectivity with which neurons are activated...
October 23, 2018: IEEE Transactions on Bio-medical Engineering
Aoife S Murray, Paddy J Gilligan, James M Bisset, Chris Nolan, Joseph M Galvin, John G Murray
BACKGROUND: Patients with cardiac implantable electronic devices (CIEDs) were traditionally denied access to MR imaging due to safety concerns. AIMS: The aim of this study was to review a single-center experience of MR imaging at 1.5T of patients with CIEDs and survey national availability of this service. METHODS: Three hundred thirty-four patients with CIEDs were included in the review. Two hundred nine patients did not progress to MRI due to non MR-conditional CIEDs, retained pacing leads, recent implant insertion, and other patient factors...
October 27, 2018: Irish Journal of Medical Science
Christoph S Dietze, Lucy Ekosso-Ejangue, Carsten W Israel, Christian G Bien, Susanne Fauser
Additional cardiologic examination for syncope is used for patients admitted for diagnostic reasons in the Epilepsy Center Bethel if, after epileptologic examination, the etiology of seizures remains uncertain and a cardiologic etiology is suspected. Therefore, we retrospectively analyzed all patient data from the diagnostic department between 02/2011 and 07/2015 to evaluate the benefits to patients of additional cardiologic examination for syncope. 78 out of 1567 patients underwent additional cardiologic examination for syncope...
October 16, 2018: Epilepsy Research
Deepak Padmanabhan, Krishna Kancharla, Majd A El-Harasis, Ameesh Isath, Nayani Makkar, Peter A Noseworthy, Paul A Friedman, Yong-Mei Cha, Suraj Kapa
BACKGROUND: Implantable loop recorders (ILRs) are effective in achieving symptom-rhythm correlation, However, diagnostic yield in routine clinical practice is not as well established. METHODS: Patients undergoing ILR implantation between April 2010 and May 2015 were included. All devices were enrolled in remote monitoring with automatic arrhythmia detection and P sense algorithms switched 'ON'. Symptom-rhythm correlation was assessed and changes in management were recorded...
October 25, 2018: Pacing and Clinical Electrophysiology: PACE
Ahmet Adiyaman, Thomas J Buist, Rypko J Beukema, Jaap Jan J Smit, Peter Paul H M Delnoy, Martin E W Hemels, Hauw T Sie, Anand R Ramdat Misier, Arif Elvan
BACKGROUND: Current guidelines recommend both percutaneous catheter ablation (CA) and surgical ablation in the treatment of atrial fibrillation, with different levels of evidence. No direct comparison has been made between minimally invasive thoracoscopic pulmonary vein isolation with left atrial appendage ligation (surgical MIPI) versus percutaneous CA comprising of pulmonary vein isolation as primary treatment of atrial fibrillation. We, therefore, conducted a randomized controlled trial comparing the safety and efficacy of these 2 treatment modalities...
October 2018: Circulation. Arrhythmia and Electrophysiology
S Oebel, G Hindricks
Syncope is a common problem in clinical practice, which affects approximately 1% of patients admitted to European emergency departments. The clinical practice guidelines for the diagnosis and management of syncope published by the European Society of Cardiology (ESC) are based on the newest scientific data in the field and have provided clinical cardiologists with a structured therapeutic approach for affected patients over many years. The previous ESC guidelines on syncope were published in 2009 and are compared to the most recent edition, which was published in 2018...
October 19, 2018: Herz
David M Page, Jacob A George, David T Kluger, Christopher Duncan, Suzanne Wendelken, Tyler Davis, Douglas T Hutchinson, Gregory A Clark
We quantified prosthesis embodiment and phantom pain reduction associated with motor control and sensory feedback from a prosthetic hand in one human with a long-term transradial amputation. Microelectrode arrays were implanted in the residual median and ulnar arm nerves and intramuscular electromyography recording leads were implanted in residual limb muscles to enable sensory feedback and motor control. Objective measures (proprioceptive drift) and subjective measures (survey answers) were used to assess prosthesis embodiment...
2018: Frontiers in Human Neuroscience
Lauren E Stone, Steven M Falowski
Spinal cord stimulation is a well-established and effective therapy in the treatment of pain. Proper patient selection and accurate lead placement are paramount in its success. Placement is a multifaceted process requiring proper paddle placement, a well thought out generator placement and appropriate means to limit complications and enhance success. Several intraoperative techniques maximize outcomes, including removal of the superior portion of the inferior level's spinous process for paddle access into the epidural space, generator pocket placement in a location that limits patient discomfort, a strain relief loop at the thoracic incision to prevent lead fractures and allow for full spinal flexibility, generator placement parallel to the body and secured in the pocket to prevent unwanted movement, and intraoperative neuromonitoring for patient comfort and more accurate lead placement compared to X-ray alone or awake placement...
October 5, 2018: Operative Neurosurgery (Hagerstown, Md.)
Luca Segreti, Kristian Ujka, Tea Cellamaro, Giulio Zucchelli, Andrea Di Cori, Ezio Soldati, Maria Grazia Bongiorni
An 86-year-old man with unremarkable clinical history complaining of asthenia and dyspnea was diagnosed with low-flow low-gradient aortic stenosis [LFLG-AS; left ventricular ejection fraction (LVEF) 40% and transaortic mean gradient 37 mmHg, increasing to 52% and 55 mmHg after dobutamine infusion]. The patient underwent transcatheter aortic valve implantation (TAVI; Edwards CENTERA™ 29, Irvine, CA, USA). The procedure and the following hospital stay were free from complications, with no changes on electrocardiography (ECG)...
June 2018: Journal of Cardiology Cases
Cynthia Yeung, Doran Drew, Sharlene Hammond, Wilma M Hopman, Damian Redfearn, Christopher Simpson, Hoshiar Abdollah, Adrian Baranchuk
Atrial fibrillation (AF) is a risk factor for ischemic stroke and reported to be associated with severe obstructive sleep apnea (OSA). The aim of this study was to determine the occurrence of newly detected AF in patients with severe OSA and no previous history of AF. Prospective observational study included patients with severe OSA (Apnea-Hypopnea Index [AHI] ≥ 30) and no history of AF. Primary outcome was detection of AF lasting ≥10 seconds. Patients were subjected to 2 24-hour Holter monitors, and if no AF was detected, implanted with a Medtronic Reveal XT implantable loop recorder...
December 1, 2018: American Journal of Cardiology
Tilman Perrin, Michael Kühne, Jan Novak
No abstract text is available yet for this article.
September 28, 2018: Indian Pacing and Electrophysiology Journal
João Ferreira-Martins, James Howard, Becker Al-Khayatt, Joseph Shalhoub, Afzal Sohaib, Matthew J Shun-Shin, Paul G Novak, Rick Leather, Laurence D Sterns, Christopher Lane, Phang Boon Lim, Prapa Kanagaratnam, Nicholas S Peters, Darrel P Francis, Markus B Sikkel
OBJECTIVE: We tested whether ablation methodology and study design can explain the varying outcomes in terms of atrial fibrillation (AF)-free survival at 1 year. BACKGROUND: There have been numerous paroxysmal AF ablation trials, which are heterogeneous in their use of different ablation techniques and study design. A useful approach to understanding how these factors influence outcome is to dismantle the trials into individual arms and reconstitute them as a large meta-regression...
September 19, 2018: Journal of Cardiovascular Electrophysiology
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