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Implantable loop recorder

Elma O'Sullivan-Greene, Tatiana Kameneva, David Trevaks, Anthony Shafton, Sophie C Payne, Robin McAllen, John B Furness, David B Grayden
 Artificial modulation of peripheral nerve signals (neuromodulation) by electrical stimulation is an innovation with potential to develop treatments that replace or supplement drugs. One function of the nervous system that can be exploited by neuromodulation is regulation of disease intensity. Optimal interfacing of devices with the nervous system requires suitable models of peripheral nerve systems so that closed-loop control can be utilized for therapeutic benefit. 
 We use physiological data to model afferent signaling in the vagus nerve that carries information about inflammation in the small intestine to the brain...
August 10, 2018: Journal of Neural Engineering
Jesse M Conyers, Prabhakar Rajiah, Richard Ahn, Suhny Abbara, Sachin S Saboo
Cardiovascular devices and hemodynamic monitoring systems continue to evolve with the goal of allowing for rapid clinical intervention and management. Cardiovascular devices including the CardioMicroelectromechanical (CardioMEMS) device, implantable loop recorder, and right ventricular (RV) leadless pacemaker are now widely used for treatment and monitoring of advanced cardiac conditions, as many of these devices have been shown to significantly improve patient outcomes. Additionally, hemodynamic monitoring devices have shown utility in monitoring patients with aortic aneurysms after endovascular aortic repair (EVAR) for early detection of Type I and Type II endoleaks...
July 2018: Diagnostic and Interventional Radiology: Official Journal of the Turkish Society of Radiology
Frederic Sacher, Laurence Jesel, Claire Borni-Duval, Valerie De Precigout, Frédéric Lavainne, Jean-Philippe Bourdenx, Atman Haddj-Elmrabet, Bruno Seigneuric, Adrien Keller, Julien Ott, Helene Savel, Yahsou Delmas, Dorothée Bazin-Kara, Nicolas Klotz, Sylvain Ploux, Sébastien Buffler, Philippe Ritter, Virginie Rondeau, Pierre Bordachar, Claire Martin, Antoine Deplagne, Sylvain Reuter, Michel Haissaguerre, Jean-Baptiste Gourraud, Cécile Vigneau, Philippe Mabo, Philippe Maury, Thierry Hannedouche, Antoine Benard, Christian Combe
OBJECTIVES: The aim of this study was to identify using implantable loop recorder (ILR) monitoring the mechanisms leading to sudden death (SD) in patients undergoing hemodialysis (HD). BACKGROUND: SD accounts for 11% to 25% of death in HD patients. METHODS: Continuous rhythm monitoring was performed using the remote monitoring capability of the ILR device in patients undergoing HD at 8 centers. Clinical, biological, and technical HD parameters were recorded and analyzed...
March 2018: JACC. Clinical Electrophysiology
Sofia Skampardoni, Dimitrios Poulikakos, Marek Malik, Darren Green, Philip A Kalra
Cardiovascular mortality is very high in chronic and end-stage kidney disease (ESKD). However, risk stratification data are lacking. Sudden cardiac deaths are among the most common cardiovascular causes of death in these populations. As a result, many studies have assessed the prognostic potential of various electrocardiographic parameters in the renal population. Recent data from studies of implantable loop recordings in haemodialysis patients from five different countries have shed light on a pre-eminent bradyarrhythmic risk of mortality...
August 6, 2018: Nephrology, Dialysis, Transplantation
Garry Hamilton, David O'Donnell, Hui-Chen Han
No abstract text is available yet for this article.
August 6, 2018: Medical Journal of Australia
Cameron T Lambert, Bruce L Wilkoff, Khaldoun G Tarakji
Cardiac implantable electronic devices (CIEDs) including pacemakers, implantable cardioverter defibrillators and loop recorders have become widespread adjuncts in the care of patients with cardiovascular disease. CIEDs provide increased diagnostic yield, better quality of life and improved longevity. While there are obvious benefits with these devices, the mere fact that these therapies involve implantation of a foreign device within the body leads to certain risks. The most feared complication associated with CIED use is infection...
July 31, 2018: Future Cardiology
Hangue Park, Muhammad S Islam, Martha A Grover, Alexander N Klishko, Boris I Prilutsky, Stephen P DeWeerth
We developed a prototype of a neural, powered, transtibial prosthesis for the use in a feline model of prosthetic gait. The prosthesis was designed for attachment to a percutaneous porous titanium implant integrated with bone, skin, and residual nerves and muscles. In the benchtop testing, the prosthesis was fixed in a testing rig and subjected to rhythmic vertical displacements and interactions with the ground at a cadence corresponding to cat walking. Several prosthesis functions were evaluated. They included sensing ground contact, control of transitions between the finite states of prosthesis loading, and a closed-loop modulation of the linear actuator gain in each loading cycle...
2018: Frontiers in Neuroscience
Wouter M van Everdingen, Alwin Zweerink, Odette A E Salden, Maarten J Cramer, Pieter A Doevendans, Albert C van Rossum, Frits W Prinzen, Kevin Vernooy, Cornelis P Allaart, Mathias Meine
Aims: This study aims to define an atrioventricular (AV) delay optimization method for cardiac resynchronization therapy (CRT) with a quadripolar left ventricular (LV) lead based on intrinsic conduction intervals. Methods and results: Heart failure patients with a left bundle branch block underwent CRT implantation with a quadripolar LV lead. Invasive LV pressure-volume loops were recorded during four biventricular and three multi-point pacing (MPP) settings, using four patient-specific paced AV delays...
July 24, 2018: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
Anastasios Petrou, Marcus Granegger, Mirko Meboldt, Marianne Schmid Daners
During the development process of active or passive cardiovascular implants, such as ventricular assist devices or vascular grafts, extensive in vitro testing is required. The aim of the study was to develop a versatile hybrid mock circulation (HMC) that can support the development of such implants that have a complex interaction with the circulation. The HMC operates based on the hardware-in-the-loop concept with a hydraulic interface of four pressure-controlled reservoirs allowing the interaction of the implant with a numerical model of the cardiovascular system...
July 23, 2018: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
Samridhi Syal, Victor Mwansa, Lovely Chhabra
Complications of insertable loop recorder (ILR) are rare. The ILR is a cardiac monitoring device placed subcutaneously in the left parasternal region. It is commonly used for continuous monitoring in patients with unexplained and recurrent episodes of palpitations and syncope. We report a rare complication of subacute breast implant rupture in a patient after ILR placement. To the best of our knowledge, this is the first such reported case in the literature.
April 2018: Methodist DeBakey Cardiovascular Journal
Paulina Przyżycka, Michał Kałowski, Izabela Poddębska, Krzysztof Kaczmarek, Paweł Ptaszyński, Jerzy K Wranicz, Iwona Cygankiewicz
Ventricular fibrillation (VF) is the most common arrhythmia leading to sudden cardiac death, but in rare cases VF can manifest as a syncope, provided that it will self-terminate. We present a case of a 45-year old female with a history of unexplained syncopal episodes despite exhaustive diagnostics. Implantable loop recorder documented an episode of idiopathic, self-terminating VF as a cause of syncope.
July 2018: Journal of Electrocardiology
Giovanni Pietro Seu, Gian Nicola Angotzi, Fabio Boi, Luigi Raffo, Luca Berdondini, Paolo Meloni
Microelectrode array (MEA) systems with up to several thousands of recording electrodes and electrical or optical stimulation capabilities are commercially available or described in the literature. By exploiting their submillisecond and micrometric temporal and spatial resolutions to record bioelectrical signals, such emerging MEA systems are increasingly used in neuroscience to study the complex dynamics of neuronal networks and brain circuits. However, they typically lack the capability of implementing real-time feedback between the detection of neuronal spiking events and stimulation, thus restricting large-scale neural interfacing to open-loop conditions...
May 30, 2018: IEEE Transactions on Biomedical Circuits and Systems
Khalil Kanjwal, Rehana Qadir, Mohammed Ruzieh, Blair P Grubb
INTRODUCTION: We previously reported on a subgroup of postural orthostatic tachycardia syndrome (POTS) patients who may also have features of neurocardiogenic syncope as well. In this subgroup of patients, we found syncope and presyncope were predominant clinical features. To understand the mechanism of syncope in this subgroup, we identified 39 patients who underwent loop recorder insertion. METHODS: We reviewed charts of 450 patients who had POTS and syncope seen at the University of Toledo Medical Center from 2003 to 2017...
July 10, 2018: Pacing and Clinical Electrophysiology: PACE
Dimitris Tsiachris, Sotiria Stabola, Athanasios Kordalis, Christodoulos Stefanadis
An injectable loop recorder was implanted in a 76-year old patient due to recurrent unexplained syncope.In the first week after implantation, asymptomatic short-term atrial fibrillation was recorded and oral anticoaguation was prescribed. Two weeks later the patient suffered a presyncope and a 5.8 seconds pause was recorded at the time of conversion of atrial fibrillation to sinus rhythm. A Micra Transcatheter Pacing System was implanted based on the minimum pacing needs. Atrial fibrillation episodes became frequent and severe symptomatic without syncope relapse...
February 2018: Journal of Atrial Fibrillation
Wen Zheng, Walter McKinney, Michael L Kashon, Daniel Pan, Vincent Castranova, Hong Kan
BACKGROUND: Heart rate variability (HRV) as a marker reflects the activity of the autonomic nervous system. The prognostic significance of HRV for cardiovascular disease has been reported in clinical and epidemiological studies. Our laboratory has reported alterations in rat heart rate variability (HRV) due to increasing activity of both sympathetic and parasympathetic nervous system after pulmonary exposure to multi-walled carbon nanotubes (MWCNTs). This suggests that pulmonary inhalation of engineered nanoparticles (ENs) may lead to functional changes in the cardiovascular system...
July 3, 2018: Nanoscale Research Letters
Antoine Pirog, Yannick Bornat, Romain Perrier, Matthieu Raoux, Manon Jaffredo, Adam Quotb, Jochen Lang, Noëlle Lewis, Sylvie Renaud
Enhanced understanding and control of electrophysiology mechanisms are increasingly being hailed as key knowledge in the fields of modern biology and medicine. As more and more excitable cell mechanics are being investigated and exploited, the need for flexible electrophysiology setups becomes apparent. With that aim, we designed Multimed, which is a versatile hardware platform for the real-time recording and processing of biosignals. Digital processing in Multimed is an arrangement of generic processing units from a custom library...
June 30, 2018: Sensors
Otis Smart, Ki S Choi, Patricio Riva-Posse, Vineet Tiruvadi, Justin Rajendra, Allison C Waters, Andrea L Crowell, Johnathan Edwards, Robert E Gross, Helen S Mayberg
Background: High-frequency Deep Brain Stimulation (DBS) of the subcallosal cingulate (SCC) region is an emerging strategy for treatment-resistant depression (TRD). This study examined changes in SCC local field potentials (LFPs). The LFPs were recorded from the DBS leads following transient, unilateral stimulation at the neuroimaging-defined optimal electrode contact. The goal was identifying a putative electrophysiological measure of target engagement during implantation. Methods: Fourteen consecutive patients underwent bilateral SCC DBS lead implantation...
2018: Frontiers in Computational Neuroscience
Pnina Rappel, Odeya Marmor, Atira S Bick, David Arkadir, Eduard Linetsky, Anna Castrioto, Idit Tamir, Sara A Freedman, Tomer Mevorach, Moran Gilad, Hagai Bergman, Zvi Israel, Renana Eitan
Obsessive-compulsive disorder (OCD) is a common and serious psychiatric disorder. Although subthalamic nucleus deep brain stimulation (DBS) has been studied as a treatment for OCD patients the underlying mechanism of this treatment and the optimal method of stimulation are unknown. To study the neural basis of subthalamic nucleus DBS in OCD patients we used a novel, implantable DBS system with long-term local field potential sensing capability. We focus our analysis on two patients with OCD who experienced severe treatment-resistant symptoms and were implanted with subthalamic nucleus DBS systems...
June 18, 2018: Translational Psychiatry
Philipp Lacour, Claas Buschmann, Christian Storm, Jens Nee, Abdul Shokor Parwani, Martin Huemer, Philipp Attanasio, Leif-Hendrik Boldt, Geraldine Rauch, Andreas Kucher, Burkert Pieske, Wilhelm Haverkamp, Florian Blaschke
BACKGROUND: Postmortem interrogations of cardiac implantable electronic devices (CIEDs), recommended at autopsy in suspected cases of sudden cardiac death, are rarely performed, and data on systematic postmortem CIED analysis in the forensic pathology are missing. The aim of the study was to determine whether nonselective postmortem CIED interrogations and data analysis are useful to the forensic pathologist to determine the cause, mechanism, and time of death and to detect potential CIED-related safety issues...
June 19, 2018: Circulation
Francesco Peruzza, Massimiliano Maines, Domenico Catanzariti, Giancarlo Tomasi, Carlo Angheben, Maurizio Del Greco
No abstract text is available yet for this article.
April 2018: Giornale Italiano di Cardiologia
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