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https://www.readbyqxmd.com/read/29161535/effect-of-dedicated-lactation-support-services-on-breastfeeding-outcomes-in-extremely-low-birth-weight-neonates
#1
Sharareh Gharib, Molly Fletcher, Richard Tucker, Betty Vohr, Beatrice E Lechner
BACKGROUND: Breastfeeding is associated with major benefits for high-risk infants born prematurely, yet this population faces significant challenges to breastfeeding. Lactation services provide successful interventions, yet the impact of lactation services on breastfeeding outcomes in preterm infants is understudied. Research aim: The provision of full-time lactation support in the neonatal intensive care unit (NICU) will improve quantitative breastfeeding measures in premature infants...
November 1, 2017: Journal of Human Lactation: Official Journal of International Lactation Consultant Association
https://www.readbyqxmd.com/read/29160571/sacral-neuromodulation-and-pregnancy-results-of-a-national-survey-carried-out-for-the-neuro-urology-committee-of-the-french-association-of-urology-afu
#2
Pauline Roulette, Evelyne Castel-Lacanal, Sylvain Sanson, Romain Caremel, Véronique Phé, Stéphane Bart, Franck Duchêne, Marianne De Sèze, Alexia Even, Andréa Manunta, Maria C Scheiber-Nogueira, Pascal Mouracade, Catherine-Marie Loche, Emmanuel Chartier-Kastler, Alain Ruffion, Gilles Karsenty, Xavier Gamé
AIMS: To assess the impact of sacral neuromodulation (SNM) on pregnancy and vice-versa, by identifying women who had received SNM for lower-urinary tract symptoms (LUTS) and had become pregnant. METHODS: A cross-sectional descriptive study was carried out based on responses to an on-line questionnaire sent to practitioners listed on the InterStim enCaptureTM National Registry. Questions were related to pre-pregnancy health and SNM efficacy, deactivation of the device, its impact on LUTS, childbirth, the infant, its reactivation and postpartum effectiveness...
November 21, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/29158370/ovarian-and-uterine-functions-in-female-survivors-of-childhood-cancers
#3
REVIEW
Ozgur Oktem, Samuel S Kim, Ugur Selek, Glenn Schatmann, Bulent Urman
Adult survivors of childhood cancers are more prone to developing poor reproductive and obstetrical outcomes than their siblings and the general population as a result of previous exposure to chemotherapy and radiation during childhood. Chemotherapy drugs exert cytotoxic effects systemically and therefore can damage the ovaries, leading to infertility, premature ovarian failure, and, to a lesser extent, spontaneous abortions. They have very limited or no deleterious effects on the uterus that can be recognized clinically...
November 20, 2017: Oncologist
https://www.readbyqxmd.com/read/29158089/opportunities-and-difficulties-for-counseling-at-the-margins-of-viability
#4
REVIEW
Patrick Myers, Bree Andrews, William Meadow
At the margins of viability, the interaction between physicians and families presents challenges but also opportunities for success. The counseling team often focuses on data: morbidity and mortality statistics and the course of a typical infant in the neonatal intensive care unit. Data that are generated on the population level can be difficult to align with the multiple facets of an individual infant's trajectory. It is also information that can be difficult to present because of framing biases and the complexities of intuiting statistical information on a personal level...
November 17, 2017: Seminars in Fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29153908/-analysis-of-obstetric-pediatric-care-in-the-perinatal-period-are-births-before-31-weeks-gestation-in-level-2b-maternity-units-avoidable
#5
I Martin, A Roussel, M-F Olieric, M Feldmann, Y Wallerich, N Trabelsi, A Miton, C Zuily-Lamy, V Valdès, J Fresson
INTRODUCTION: Regionalization of perinatal care has been developed to improve the survival of preterm babies. The mortality rate is higher among very premature infants born outside level-3 maternity units. The objective of this study was to evaluate the preventability of these very premature births occurring outside recommendations within level-2B maternity units. The secondary objective was to describe the care of premature infants between 23 and 24 weeks. METHODS: This is a single-center retrospective qualitative study of the care delivery pathways...
November 16, 2017: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/29152912/physiological-and-anatomical-dead-space-in-mechanically-ventilated-newborn-infants
#6
Theodore Dassios, Paul Dixon, Ann Hickey, Sotirios Fouzas, Anne Greenough
OBJECTIVES: To compare the anatomical (VD-Ana ) and alveolar dead space (VD-Alv ) in term and prematurely born infants and identify the clinical determinants of those indices. WORKING HYPOTHESIS: VD-Ana and VD-Alv will be higher in prematurely born compared to term born infants. STUDY DESIGN: Retrospective analysis of data collected at King's College Hospital NHS Foundation Trust, London, UK. PATIENT SELECTION: Fifty-six infants (11 term, 45 preterm) were studied at a median age of 8 (IQR 2-33) days...
November 20, 2017: Pediatric Pulmonology
https://www.readbyqxmd.com/read/29150862/randomised-crossover-trial-showed-that-using-breast-milk-or-sucrose-provided-the-same-analgesic-effect-in-preterm-infants-of-at-least-28-weeks
#7
L Collados-Gómez, P Ferrera-Camacho, E Fernandez-Serrano, V Camacho-Vicente, C Flores-Herrero, A M García-Pozo, R Jiménez-García
AIM: Repeated, on-going exposure to pain influences the growth, cognitive and motor functions, behaviour, personality and neurodevelopment of preterm infants. We compared the analgesic effects of expressed breast milk and 24% oral sucrose on preterm neonates during venipuncture. METHODS: This multicentre randomised, non-inferiority, cross-over trial focused on five neonatal university units in Madrid, Spain, from October 2013 to October 2014. It comprised 66 preterm infants born at less than 37 weeks and randomly split into two groups...
November 18, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/29149439/trends-in-utilization-of-outpatient-respiratory-syncytial-virus-prophylaxis-with-palivizumab-among-medicaid-and-commercially-insured-infants
#8
Melissa Pavilack, Robert A Clifford, Tara Gonzales, Amanda M Kong, Sally Wade, Kimmie K McLaurin
INTRODUCTION: Palivizumab is indicated for the prevention of respiratory syncytial virus (RSV) infection in high-risk children. Previous palivizumab utilization studies examined prior authorization claims but did not examine utilization within insured populations as a whole. This study describes outpatient palivizumab utilization trends and characterizes high-risk infants receiving palivizumab within Medicaid- and commercially insured populations. METHODS: Infants born July 1, 2003 through June 30, 2013 were identified in the MarketScan(®) Multistate Medicaid and Commercial claims databases...
November 17, 2017: Infectious Diseases and Therapy
https://www.readbyqxmd.com/read/29148239/metabolic-signature-of-microvescicles-from-umbilical-cord-mesenchimal-stem-cells-of-preterm-and-term-infants
#9
Maurizio Bruschi, Laura Santucci, Silvia Ravera, Martina Bartolucci, Andrea Petretto, Daniela Calzia, Gianmarco Ghiggeri, Luca A Ramenghi, Giovanni Candiano, Isabella Panfoli
PURPOSE: Microvesicles, 200-1000 nm bodies budding from the cell plasma membrane, are a promising source of biomarkers. This study aimed at comparing the proteome of Microvesicles collected by ultracentrifugation from cultured Mesenchymal Stem Cells from Human Umbilical Cord of Preterm newborns(<34-weeks gestational age) in comparison to infants at Term(≥37 weeks). This discovery study was designed to establish the signature of prematurity. EXPERIMENTAL DESIGN: Orbitrap mass spectrometry, statistical, bioinformatics and biochemical analyses were employed...
November 16, 2017: Proteomics. Clinical Applications
https://www.readbyqxmd.com/read/29145693/early-erythropoiesis-stimulating-agents-in-preterm-or-low-birth-weight-infants
#10
REVIEW
Arne Ohlsson, Sanjay M Aher
BACKGROUND: Preterm infants have low plasma levels of erythropoietin (EPO), providing a rationale for the use of erythropoiesis-stimulating agents (ESAs) to prevent or treat anaemia and to provide neuro protection and protection against necrotising enterocolitis (NEC). Darbepoetin (Darbe) and EPO are currently available ESAs. OBJECTIVES: To assess the effectiveness and safety of ESAs (erythropoietin (EPO) and/or Darbe) initiated early (before eight days after birth) compared with placebo or no intervention in reducing red blood cell (RBC) transfusions, adverse neurological outcomes, and feeding intolerance including necrotising enterocolitis (NEC) in preterm and/or low birth weight infants...
November 16, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29145270/study-on-the-adverse-effects-following-chemotherapy-for-breast-cancer-diagnosis-during-pregnancy-the-first-case-report-in-china
#11
Xin Ye, Qi He, Xiaoyun Zhou
RATIONALE: Treatment of breast cancer during pregnancy (BCP) remains a challenge to physicians. Surgery and chemotherapy during pregnancy are widely used for the treatment of BCP. Herein, we reported 3 Chinese patients with BCP who underwent chemotherapy during pregnancy and were followed up for adverse effects. PATIENT CONCERNS: Three female patients (case 1, case 2, and case 3) of 37-, 32-, and 28-year-old with breast masses were enrolled. Case 1 had been pregnant for over 4 months, case 2 over 7 months, and case 3 for 7 months...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29144240/trial-of-music-sucrose-and-combination-therapy-for-pain-relief-during-heel-prick-procedures-in-neonates
#12
Swapnil R Shah, Shahajahan Kadage, John Sinn
OBJECTIVE: To compare the effectiveness of music, oral sucrose, and combination therapy for pain relief in neonates undergoing a heel prick procedure. STUDY DESIGN: This randomized, controlled, blinded crossover clinical trial included stable neonates >32 weeks of postmenstrual age. Each neonate crossed over to all 3 interventions in random order during consecutive heel pricks. A video camera on mute mode recorded facial expressions, starting 2 minutes before until 7 minutes after the heel prick...
November 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/29143635/a-systematic-review-of-concepts-related-to-women-s-empowerment-in-the-perinatal-period-and-their-associations-with-perinatal-depressive-symptoms-and-premature-birth
#13
Esmeralda R Garcia, Ilona S Yim
BACKGROUND: The perinatal period, which we here define as pregnancy and the first year postpartum, is a time in women's lives that involves significant physiological and psychosocial change and adjustment, including changes in their social status and decision-making power. Supporting women's empowerment at this particular time in their lives may be an attractive opportunity to create benefits for maternal and infant health outcomes such as reductions in perinatal depressive symptoms and premature birth rates...
November 8, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29142745/determinants-of-prenatal-anemia-in-ethiopia
#14
Abera Abay, Haile Woldie Yalew, Amare Tariku, Ejigu Gebeye
Background: Anemia is responsible for 20% of maternal mortality worldwide, and it is associated with premature birth, low birth weight, and infant mortality. In Ethiopia, about 22% of pregnant women are anemic. However, literatures are limited, therefore, this study aimed to investigate the prevalence and associated factors of anemia among pregnant women attending antenatal care (ANC) in Asossa Zone Public Health Institutions, northwest Ethiopia. Methods: A facility based cross-sectional study was conducted from February to March 2016...
2017: Archives of Public Health, Archives Belges de Santé Publique
https://www.readbyqxmd.com/read/29141932/umbilical-artery-perforation-a-potentially-life-threatening-complication-of-umbilical-artery-catheterisation
#15
Daniel Molanus, Machteld van Scherpenzeel, Joep Derikx, Frank van den Dungen
Umbilical artery catheterisation is frequently performed in preterm or critically ill newborn infants for invasive monitoring of blood pressure and blood sampling for laboratory tests. It is associated with well-known complications like catheter-related infections, thromboembolic events and aneurysmal formation of the aorta. In this report, we present another major complication of umbilical artery catheterisation: umbilical artery perforation. This complication occurred in a prematurely born infant and resulted in severe haemorrhagic shock, subsequent renal failure and severe periventricular leukomalacia...
November 14, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29141590/health-nutrition-and-development-of-children-born-preterm-and-low-birth-weight-in-rural-rwanda-a-cross-sectional-study
#16
Catherine M Kirk, Jean Claude Uwamungu, Kim Wilson, Bethany L Hedt-Gauthier, Neo Tapela, Peter Niyigena, Christian Rusangwa, Merab Nyishime, Evrard Nahimana, Fulgence Nkikabahizi, Christine Mutaganzwa, Eric Ngabireyimana, Francis Mutabazi, Hema Magge
BACKGROUND: As care for preterm and low birth weight (LBW) infants improves in resource-limited settings, more infants are surviving the neonatal period. Preterm and (LBW) infants are at high-risk of nutritional and medical comorbidities, yet little is known about their developmental outcomes in low-income countries. This study evaluated the health, nutritional, and developmental status of preterm/LBW children at ages 1-3 years in Rwanda. METHODS: Cross-sectional study of preterm/LBW infants discharged between October 2011 and October 2013 from a hospital neonatal unit in rural Rwanda...
November 15, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/29136541/impact-of-neonatal-morbidity-on-the-risk-of-developmental-delay-in-late-preterm-infants
#17
Sílvia Martínez-Nadal, Xavier Demestre, Luisa Schonhaut, Sergio R Muñoz, Pere Sala
BACKGROUND: Late preterm infants (LPI) have a higher risk of developmental delay (DD) than term-born infants. The association of perinatal complications with specific morbidity is not clear. AIM: (1) To compare the risk of DD at 4years of age between LPI who have presence or absence of any morbidity associated with the prematurity at birth, called complicated (cLPI) or uncomplicated (uLPI), and term-born infants, (2) to determine maternal and perinatal factors associated with risk of DD, and (3) to analyze, in LPI, the association between perinatal morbidity and risk of DD...
November 11, 2017: Early Human Development
https://www.readbyqxmd.com/read/29135822/premature-infants-have-lower-gastric-digestion-capacity-for-human-milk-proteins-than-term-infants
#18
Veronique Demers-Mathieu, Yunyao Qu, Mark A Underwood, Robyn Borghese, David Charles Dallas
OBJECTIVES: Whether premature infants have lower gastric protein digestive capacity than term infants and the extent to which human milk proteases contribute to overall gastric digestion are unknown and were investigated in this study. METHODS: Human milk and infant gastric samples were collected from 16 preterm (24-32 wk gestational age (GA)) and 6 term (38-40 wk GA) mother-infant pairs within a range of 5-42 days postnatal age. For each pair, an aliquot of human milk was adjusted to pH 4...
November 10, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29135357/short-term-refractive-effects-of-propranolol-hydrochloride-prophylaxis-on-retinopathy-of-prematurity-in-very-preterm-newborns
#19
Levent Korkmaz, Cagatay Karaca, Mustafa Ali Akin, Osman Bastug, Mustafa Sahiner, Ahmet Ozdemir, Tamer Gunes, Mehmet Adnan Ozturk, Selim Kurtoglu
PURPOSE: Retinopathy of prematurity (ROP) is one of the major problems of surviving premature infants with several ophthalmic morbidities such as increased risk of refractive errors, strabismus, and cortical visual impairment. Use of propranolol hydrochloride (PH) for the prevention of ROP is a new promising treatment modality. However, long-term effects are still to be defined. In our study, we aimed to investigate the short-term refractive effects of PH used for ROP prophylaxis in very preterm newborns...
November 14, 2017: Current Eye Research
https://www.readbyqxmd.com/read/29134703/origin-and-dynamics-of-oligodendrocytes-in-the-developing-brain-implications-for-perinatal-white-matter-injury
#20
REVIEW
Erik van Tilborg, Caroline G M de Theije, Maurik van Hal, Nienke Wagenaar, Linda S de Vries, Manon J Benders, David H Rowitch, Cora H Nijboer
Infants born prematurely are at high risk to develop white matter injury (WMI), due to exposure to hypoxic and/or inflammatory insults. Such perinatal insults negatively impact the maturation of oligodendrocytes (OLs), thereby causing deficits in myelination. To elucidate the precise pathophysiology underlying perinatal WMI, it is essential to fully understand the cellular mechanisms contributing to healthy/normal white matter development. OLs are responsible for myelination of axons. During brain development, OLs are generally derived from neuroepithelial zones, where neural stem cells committed to the OL lineage differentiate into OL precursor cells (OPCs)...
November 14, 2017: Glia
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