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https://www.readbyqxmd.com/read/29458218/effects-of-curcuminoids-plus-piperine-on-glycemic-hepatic-and-inflammatory-biomarkers-in-patients-with-type-2-diabetes-mellitus-a-randomized-double-blind-placebo-controlled-trial
#1
Yunes Panahi, Nahid Khalili, Ebrahim Sahebi, Soha Namazi, Luis E Simental-Mendía, Muhammed Majeed, Amirhossein Sahebkar
INTRODUCTION: Curcuminoids have been shown to reduce glycemia and related complications in diabetes. In the present study, we evaluated the impact of curcuminoids plus piperine administration on glycemic, hepatic and inflammatory biomarkers in type 2 diabetes (T2D) patients. METHODS: T2D patients aged 18-65 years were enrolled in a randomized double-blind placebo-controlled trial and randomly allocated to standard-of-care treatment and dietary advises plus either curcuminoids (daily dose of 500 mg/day co-administered with piperine 5 mg/day) or placebo for a period of 3 months...
February 19, 2018: Drug Research
https://www.readbyqxmd.com/read/29458163/dna-adduct-profiling-of-in-vitro-colonic-meat-digests-to-map-red-vs-white-meat-genotoxicity
#2
Lieselot Y Hemeryck, Caroline Rombouts, Ellen De Paepe, Lynn Vanhaecke
The consumption of red meat has been linked to an increased colorectal cancer (CRC) risk. One of the major hypotheses states that heme iron (present in red meat) stimulates the formation of genotoxic N-nitroso compounds (NOCs) and lipid peroxidation products (LPOs). By means of DNA adductomics, chemically induced DNA adduct formation can be mapped in relation to e.g. dietary exposures. In this study, this state-of-the-art methodology was used to investigate alkylation and (lipid per)oxidation induced DNA adduct formation in in vitro red vs...
February 16, 2018: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29458159/strawberry-extracts-efficiently-counteract-inflammatory-stress-induced-by-the-endotoxin-lipopolysaccharide-in-human-dermal-fibroblast
#3
Massimiliano Gasparrini, Francesca Giampieri, Tamara Y Forbes-Hernandez, Sadia Afrin, Danila Cianciosi, Patricia Reboredo-Rodriguez, Alfonso Varela-Lopez, JiaoJiao Zhang, Josè L Quiles, Bruno Mezzetti, Stefano Bompadre, Maurizio Battino
A protracted pro-inflammatory state is the common denominator in the development, progression and complication of the common chronic diseases. Dietary antioxidants represent an efficient tool to counteract this inflammatory state. The aim of the present work was to evaluate the effects of strawberry extracts on inflammation evoked by E. Coli lipopolysaccharide in Human Dermal Fibroblast, by measuring reactive oxygen species production, apoptosis rate, antioxidant enzymes activity, mitochondria functionality and also investigating the molecular pathway involved in inflammatory and antioxidant response...
February 16, 2018: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29458115/effect-of-acek-acesulfame-potassium-on-brain-function-under-dietary-restriction-in-mice
#4
Daisuke Ibi, Fumika Suzuki, Masayuki Hiramatsu
People preferably take zero or low-calorie beverages and foods with artificial sweeteners even though it has been recently suggested that long-term artificial sweetener use affects physiological functions. In addition, a lower body weight was considered to be more healthful, but an abnormally low body weight caused by an excessive diet has been reported to cause health problems. Acesulfame potassium (AceK) is one of the most commonly used for foods and beverages because of its resistance to thermal degradation and marked sweetness...
February 16, 2018: Physiology & Behavior
https://www.readbyqxmd.com/read/29458053/circulating-bile-acids-in-healthy-adults-respond-differently-to-a-dietary-pattern-characterized-by-whole-grains-legumes-and-fruits-and-vegetables-compared-to-a-diet-high-in-refined-grains-and-added-sugars-a-randomized-controlled-crossover-feeding-study
#5
Bigina N R Ginos, Sandi L Navarro, Yvonne Schwarz, Haiwei Gu, Dongfang Wang, Timothy W Randolph, Ali Shojaie, Meredith A J Hullar, Paul D Lampe, Mario Kratz, Marian L Neuhouser, Daniel Raftery, Johanna W Lampe
OBJECTIVE: The effects of diets high in refined grains on biliary and colonic bile acids have been investigated extensively. However, the effects of diets high in whole versus refined grains on circulating bile acids, which can influence glucose homeostasis and inflammation through activation of farnesoid X receptor (FXR) and G protein-coupled bile acid receptor 1 (TGR5), have not been studied. MATERIALS AND METHODS: We conducted a secondary analysis from a randomized controlled crossover feeding trial (NCT00622661) in 80 healthy adults (40 women/40 men, age 18-45 years) from the greater Seattle Area, half of which were normal weight (BMI 18...
February 16, 2018: Metabolism: Clinical and Experimental
https://www.readbyqxmd.com/read/29457996/the-tyg-index-cutoff-point-and-its-association-with-body-adiposity-and-lifestyle-in-children
#6
Sarah A Vieira Ribeiro, Poliana C A Fonseca, Cristiana S Andreoli, Andréia Q Ribeiro, Helen H M Hermsdorff, Patrícia F Pereira, Silvia E Priore, Sylvia C C Franceschini
OBJECTIVE: To investigate the factors associated with insulin resistance in children aged 4-7 years, and to identify the cutoff point of the triglyceride-glucose index for the prediction of IR in this population. METHODS: A cross-sectional study was conducted with 403 children from a retrospective cohort. Insulin resistance was also evaluated in a sub-sample using the HOMA index. Four indicators of body adiposity were assessed: body mass index, waist-to-height ratio, and the percentages of total and central body fat...
February 16, 2018: Jornal de Pediatria
https://www.readbyqxmd.com/read/29457937/support-with-nutrition-for-women-receiving-chemotherapy-for-breast-cancer
#7
Fiona Gilmour, Anne Williams
Nurses are in a unique position to provide nutritional advice and information to women with breast cancer who are undergoing chemotherapy, supporting them with making decisions regarding nutrition and diet. This narrative review evaluated the research evidence relating to the nutritional challenges experienced during chemotherapy and the most effective approaches for supporting women in dietary choice. Weight gain was identified as a specific problem for women undergoing chemotherapy. The evidence indicated that information about nutrition and food preparation support may go some way in assisting women to overcome some of the nutrition-related difficulties experienced during chemotherapy treatment for breast cancer...
February 22, 2018: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/29457678/micronutrients-dietary-patterns-associated-with-type-2-diabetes-among-women-of-the-e3n-epic-cohort-study
#8
Francesca Romana Mancini, Courtney Dow, Aurélie Affret, Kalina Rajaobelina, Laureen Dartois, Beverley Balkau, Fabrice Bonnet, Marie-Christine Boutron-Ruault, Guy Fagherazzi
BACKGROUND: Micronutrients play a key role in type 2 diabetes, but methodological difficulties arise from their collinearity and interdependencies with foods. The objective of the present study is to identify micronutrient dietary patterns in the E3N-EPIC cohort and to investigate their association with type 2 diabetes risk. METHODS: Principal component analysis was applied to identify micronutrient patterns among 71 270 women from the E3N-EPIC cohort. Associations between micronutrient patterns and type 2 diabetes risk were quantified by hazards ratios (95% confidence intervals) from Cox proportional hazards regression models, adjusted on potential confounders...
February 19, 2018: Journal of Diabetes
https://www.readbyqxmd.com/read/29457582/green-leafy-and-cruciferous-vegetable-consumption-and-risk-of-type-2-diabetes-results-from-the-singapore-chinese-health-study-and-meta-analysis
#9
Guo-Chong Chen, Woon-Puay Koh, Jian-Min Yuan, Li-Qiang Qin, Rob M van Dam
Several previous prospective studies suggest that consumption of green leafy and cruciferous vegetables may lower the risk of type 2 diabetes (T2D). We investigated the association between consumption of different types of vegetables in relation to T2D risk in an Asian Population. We included 45 411 participants (age range: 45-74 years) of the Singapore Chinese Health Study (SCHS) free of diabetes, cancer or CVD at baseline (1993-1998). Dietary information was collected using a validated FFQ. Physician-diagnosed incident diabetes was reported at follow-up I (1999-2004) and II (2006-2010) interviews...
February 19, 2018: British Journal of Nutrition
https://www.readbyqxmd.com/read/29457580/food-and-beverage-intakes-according-to-physical-activity-levels-in-european-children-the-idefics-identification-and-prevention-of-dietary-and-lifestyle-induced-health-effects-in-children-and-infants-study
#10
Alba M Santaliestra-Pasías, Jaime E Llamas Dios, Ole Sprengeler, Antje Hebestreit, Stefaan De Henauw, Gabriele Eiben, Regina Felsö, Fabio Lauria, Michael Tornaritis, Toomas Veidebaum, Valeria Pala, Luis A Moreno
OBJECTIVE: Physical activity (PA) levels and dietary habits are considered some of the most important factors associated with obesity. The present study aimed to examine the association between PA level and food and beverage consumption in European children (2-10 years old). Design/Setting/Subjects A sample of 7229 children (49·0 % girls) from eight European countries participating in the IDEFICS (Identification and prevention of Dietary and lifestyle induced health EFfects In Children and infantS) study was included...
February 19, 2018: Public Health Nutrition
https://www.readbyqxmd.com/read/29457523/natural-products-for-controlling-hyperlipidemia-review
#11
Walid Hamdy El-Tantawy, Abeer Temraz
Hyperlipidemia is an abnormality of lipid metabolism, characterized by an elevation of total cholesterol, triglyceride, and low density lipoprotein-cholesterol, and/or a decreasing of high density lipoprotein cholesterol in circulating levels. Hyperlipidemia has been ranked as one of the greatest risk factors contributing to prevalence and severity of coronary heart diseases. Hyperlipidemia-associated lipid disorders are considered the cause of atherosclerotic cardiovascular disease. There has been a growing interest in natural products and their role in the maintenance and improvement of health and wellness...
February 19, 2018: Archives of Physiology and Biochemistry
https://www.readbyqxmd.com/read/29457511/a-probabilistic-intake-model-to-estimate-the-impact-of-reformulation-by-the-food-industry-among-irish-consumers
#12
S Pigat, A Connolly, M Cushen, M Cullen, C O'Mahony
This project quantified the impact that voluntary reformulation efforts of the food industry had on the Irish population's nutrient intake. Nutrient composition data on reformulated products were collected from 14 major food companies for two years, 2005 and 2012. Probabilistic intake assessments were performed using the Irish national food consumption surveys as dietary intake data. The nutrient data were weighted by market shares replacing existing food composition data for these products. The reformulation efforts assessed, significantly reduced mean energy intakes by up to 12 kcal/d (adults), 15 kcal/d (teens), 19 kcal/d (children) and 9 kcal/d (pre-schoolers)...
February 19, 2018: International Journal of Food Sciences and Nutrition
https://www.readbyqxmd.com/read/29457493/the-impact-of-vitamin-d-supplementation-on-attention-deficit-hyperactivity-disorder-in-children
#13
Hatem Hamed Elshorbagy, Naglaa Fathy Barseem, Waleed Elsayed Abdelghani, Hany Abdelaziz Ibrahim Suliman, Ashraf Hamed Al-Shokary, Sameh Elsayed Abdulsamea, Akram Elshafey Elsadek, Yehia Hamed Abdel Maksoud, Dalia Mohamed Abd El-Hassib Nour El Din
BACKGROUND: The role of nutrients and dietary factors in attention-deficit hyperactivity disorder (ADHD) remains unclear. OBJECTIVES: The primary objective was to evaluate the serum vitamin D level in children with a diagnosis of ADHD. The secondary objective was to detect the effect of vitamin D supplementation on cognitive function in those with vitamin D deficiency. METHODS: A total of 50 children with ADHD and 40 healthy controls were included in the study...
February 1, 2018: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/29457232/tackling-obesity-and-disease-the-culprit-is-sugar-the-response-is-legal-regulation
#14
Lawrence O Gostin
It is staggering to observe the new normal in America: 37.9 percent of adults are obese, and 70.7 percent are either obese or overweight. One out of every five minors is obese. The real tragedy, of course, is the disability, suffering, and early death that devastates families and communities. But all of society pays, with the annual medical cost estimated at $147 billion. The causal pathways are complex, but if we drill down, sugar is a deeply consequential pathway to obesity, and the single greatest dietary source is sugar-sweetened beverages (SSBs)...
January 2018: Hastings Center Report
https://www.readbyqxmd.com/read/29457224/factors-associated-with-nutritional-status-and-dietary-practices-of-bangladeshi-adolescents-in-early-pregnancy
#15
Malay K Mridha, Susana L Matias, Charles D Arnold, Kathryn G Dewey
Bangladesh has a high prevalence of adolescent pregnancy, but little is known about the nutritional status and dietary practices of Bangladeshi adolescents in early pregnancy or associated factors. We used the baseline data of 1552 pregnant adolescents from a longitudinal, cluster-randomized effectiveness trial conducted in northwest Bangladesh. Forty-four percent of the adolescents were short for their age, 36% had low body mass index, 28% were anemic, 10% had iron deficiency, and 32% had vitamin A deficiency...
February 18, 2018: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/29457204/prevention-and-management-of-childhood-obesity
#16
Aashima Dabas, Anju Seth
Childhood obesity has been recognized as a global pandemic. Preventive strategies have proven to be the most effective public health intervention in curbing this pandemic. A multi-component approach involving dietary modification and advocacy for a healthy lifestyle comprising of regular physical activity, minimizing screen time and behavioral interventions have been found beneficial in preventing obesity. A life-cycle approach has been recommended where preventive interventions go as far back as affecting maternal, fetal and early childhood nutrition and lifestyle...
February 19, 2018: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/29457002/early-dietary-patterns-and-microbiota-development-still-a-way-to-go-from-descriptive-interactions-to-health-relevant-solutions
#17
REVIEW
Patricia Iozzo, Elena Sanguinetti
Early nutrition and growth in the initial years of life are important determinants of later body weight and metabolic health in humans, and the current epidemic of obesity involving children requires a better understanding of causal and protective mechanisms and components in infant foods. This review focuses on recent evidence implicating feeding modes (e.g., breast milk and formula milk) and dietary transitions toward complementary foods in the progression of microbiota maturation in children. The literature exploring body weight outcomes of microbiota changes induced by diet in early life is limited...
2018: Frontiers in Nutrition
https://www.readbyqxmd.com/read/29456587/dietary-diversity-and-associated-factors-among-children-of-orthodox-christian-mothers-caregivers-during-the-fasting-season-in-dejen-district-north-west-ethiopia
#18
Gemechu Kumera, Endalkachew Tsedal, Mulatu Ayana
Background: Proper feeding practices during early childhood is fundamental for optimal child growth and development. However, scientific evidences on the determinants of dietary diversity are scanty. Particularly, the impact of fasting on children`s dietary diversity is not explored in Ethiopia. The aim of this study was to assess dietary diversity and associated factors among children aged 6-23 months, whose mothers/care-givers were Orthodox Christians during the fasting season (Lent), in Dejen District, North West Ethiopia, 2016...
2018: Nutrition & Metabolism
https://www.readbyqxmd.com/read/29456586/dietary-canolol-protects-the-heart-against-the-deleterious-effects-induced-by-the-association-of-rapeseed-oil-vitamin-e-and-coenzyme-q10-in-the-context-of-a-high-fat-diet
#19
Thibault Leger, Isabelle Hininger-Favier, Frédéric Capel, Alain Geloen, Jean-Paul Rigaudière, Chrystèle Jouve, Elodie Pitois, Gaelle Pineau, Carole Vaysse, Jean-Michel Chardigny, Marie-Caroline Michalski, Corinne Malpuech-Brugère, Luc Demaison
Background: Obesity progressively leads to cardiac failure. Omega-3 polyunsaturated fatty acids (PUFA) have been shown to have cardio-protective effects in numerous pathological situations. It is not known whether rapeseed oil, which contains α-linolenic acid (ALA), has a similar protective effect. Omega-3 PUFAs are sensitive to attack by reactive oxygen species (ROS), and lipid peroxidation products could damage cardiac cells. We thus tested whether dietary refined rapeseed oil (RSO) associated with or without different antioxidants (vitamin E, coenzyme Q10 and canolol) is cardio-protective in a situation of abdominal obesity...
2018: Nutrition & Metabolism
https://www.readbyqxmd.com/read/29456553/silencing-of-iron-and-heme-related-genes-revealed-a-paramount-role-of-iron-in-the-physiology-of-the-hematophagous-vector-rhodnius-prolixus
#20
Ana B Walter-Nuno, Mabel L Taracena, Rafael D Mesquita, Pedro L Oliveira, Gabriela O Paiva-Silva
Iron is an essential element for most organisms However, free iron and heme, its complex with protoporphyrin IX, can be extremely cytotoxic, due to the production of reactive oxygen species, eventually leading to oxidative stress. Thus, eukaryotic cells control iron availability by regulating its transport, storage and excretion as well as the biosynthesis and degradation of heme. In the genome of Rhodnius prolixus , the vector of Chagas disease, we identified 36 genes related to iron and heme metabolism We performed a comprehensive analysis of these genes, including identification of homologous genes described in other insect genomes...
2018: Frontiers in Genetics
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