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https://www.readbyqxmd.com/read/29913481/deficiency-of-long-chain-polyunsaturated-fatty-acids-in-phenylketonuria-a-cross-sectional-study
#1
Sławomira Drzymała-Czyż, Łukasz Kałużny, Patrycja Krzyżanowska-Jankowska, Dariusz Walkowiak, Renata Mozrzymas, Jarosław Walkowiak
The etiology of altered blood fatty acid (FA) profile in phenylketonuria (PKU) is understood only partially. We aimed to determine whether FAs deficiency is dependent on the diet or metabolic disturbances. The study comprised 40 PKU patients (20 female, 20 male; aged 11 to 35 years; 12 children and 28 adults) and 40 healthy subjects (HS; 20 female, 20 male, aged 18 to 33 years). We assessed the profile of FAs (gas chromatography/mass spectrometry) and analyzed the 72-hour dietary recalls. The amount of C14:0, C16:0 and C16:1n-7, C18:1n-9 did not differ between the analyzed groups...
2018: Acta Biochimica Polonica
https://www.readbyqxmd.com/read/29913456/long-term-oral-administration-of-theaphenon-e-improves-cardiomyocyte-mechanics-and-calcium-dynamics-by-affecting-phospholamban-phosphorylation-and-atp-production
#2
Leonardo Bocchi, Monia Savi, Valeria Naponelli, Rocchina Vilella, Gianluca Sgarbi, Alessandra Baracca, Giancarlo Solaini, Saverio Bettuzzi, Federica Rizzi, Donatella Stilli
BACKGROUND/AIMS: Dietary polyphenols from green tea have been shown to possess cardio-protective activities in different experimental models of heart diseases and age-related ventricular dysfunction. The present study was aimed at evaluating whether long term in vivo administration of green tea extracts (GTE), can exert positive effects on the normal heart, with focus on the underlying mechanisms. METHODS: The study population consisted of 20 male adult Wistar rats...
June 15, 2018: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/29913232/genotoxic-alkenylbenzene-flavourings-a-contribution-to-risk-assessment
#3
Célia Martins, José Rueff, António S Rodrigues
Alkenylbenzenes, such as estragole, myristicin and eugenol, are present is several flavourings, functional foods, plant food supplements (PFS) and in complementary and alternative medicines (CAM) including herbal medicines. The increase in consumption in functional foods observed worldwide requires a strict analysis of the scientific validity of their benefits and risk-benefit ratio associated with their intake. Some instances of acute toxicity have been reported associated with the use of herbal medicines and PFS, in particular because quality control is poor, and this poses a risk especially in internet marketed products...
June 15, 2018: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29913120/impact-of-diet-on-irinotecan-toxicity-in-mice
#4
Pankajini Mallick, Pranav Shah, Michael M Ittmann, Meghna Trivedi, Ming Hu, Song Gao, Romi Ghose
Irinotecan is highly effective in the treatment of metastatic colorectal cancer as well as many other cancers. However, irinotecan is known to cause severe diarrhea, which pose significant problems in patients undergoing irinotecan based chemotherapy. Dietary and herbal components have shown promise in improving gastrointestinal health. Therefore, we compared the effect of grain-based chow diet containing phytoestrogens and corn/alfalfa as fat source to purified diets containing either animal-derived fat source (lard) or plant-derived fat source (soybean oil) on irinotecan-induced toxicities in mice...
June 15, 2018: Chemico-biological Interactions
https://www.readbyqxmd.com/read/29913013/prevalence-of-dietary-supplement-use-in-us-children-and-adolescents-2003-2014
#5
Dima M Qato, G Caleb Alexander, Jenny S Guadamuz, Stacy Tessler Lindau
No abstract text is available yet for this article.
June 18, 2018: JAMA Pediatrics
https://www.readbyqxmd.com/read/29912978/mediterranean-diet-and-quality-of-life-baseline-cross-sectional-analysis-of-the-predimed-plus-trial
#6
Iñigo Galilea-Zabalza, Pilar Buil-Cosiales, Jordi Salas-Salvadó, Estefanía Toledo, Carolina Ortega-Azorín, Javier Díez-Espino, Zenaida Vázquez-Ruiz, María Dolores Zomeño, Jesús Vioque, José Alfredo Martínez, Dora Romaguera, Napoleón Perez-Farinos, José López-Miranda, Ramón Estruch, Aurora Bueno-Cavanillas, Fernando Arós, Josep Antoni Tur, Francisco Tinahones, Lluis Serra-Majem, Alba Marcos-Delgado, Manuel Ortega-Calvo, Clotilde Vázquez, Xavier Pintó, Josep Vidal, Lidia Daimiel, Miguel Delgado-Rodríguez, Pilar Matía, Dolores Corella, Andrés Diaz-López, Nancy Babio, Miguel Angel Muñoz, Montse Fitó, Sandra González-Palacios, Itziar Abete, Antonio García-Rios, Emilio Ros, Miguel Ángel Martínez-González
We assessed if a 17-item score capturing adherence to a traditional Mediterranean diet (MedDiet) was associated with better health-related quality of life among older Spanish men and women with overweight or obesity harboring the metabolic syndrome. We analyzed baseline data from 6430 men and women (age 55-70 years) participating in the PREDIMED-Plus study. PREDIMED-Plus is a multi-centre randomized trial testing an energy-restricted MedDiet combined with promotion of physical activity and behavioral therapy for primary cardiovascular prevention compared to a MedDiet alone...
2018: PloS One
https://www.readbyqxmd.com/read/29912953/seasonal-variations-in-diet-composition-diet-breadth-and-dietary-overlap-between-three-commercially-important-fish-species-within-a-flood-pulse-system-the-tonle-sap-lake-cambodia
#7
Kong Heng, Mathieu Chevalier, Sovan Lek, Pascal Laffaille
Tropical lakes and their associated floodplain habitats are dynamic habitat mosaics strongly influenced by seasonal variations in hydrologic conditions. In flood-pulse systems, water level oscillations directly influence the connectivity to floodplain habitats for fish. Here, we aimed to investigate whether seasonal changes in the water level of a flood-pulse system (the Tonle Sap Lake, Cambodia) differentially affect diet breadth and dietary overlap of three common and commercially important fish species (Anabas testudineus, Boesemania microplepis and Notopterus notopterus) presenting important differences in their life-cycle (e...
2018: PloS One
https://www.readbyqxmd.com/read/29912757/dietary-interventions-in-liver-cirrhosis
#8
Chu Kion Yao, James Fung, Natural Hoi Sing Chu, Victoria Ping Yi Tan
Liver cirrhosis is associated with significant nutritional risks that often result in serious hepatic complications and poor survival rates. Diet is an important but underutilized aspect in the treatment modality of cirrhosis. Therefore, the aims of this review are to ascertain nutritional risks associated with its pathophysiology and to summarize existing evidence that support dietary recommendations for managing this patient population. Alterations in substrate utilization for energy production is a main feature of liver cirrhosis, resulting in increased catabolism of protein stores and a predisposition toward protein-energy malnutrition, even in the early stages of the disease...
June 16, 2018: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/29912753/comparison-of-lactase-variant-mcm6-13910-c-t-testing-and-self-report-of-dairy-sensitivity-in-patients-with-irritable-bowel-syndrome
#9
Ann E Almazar, Joseph Y Chang, Joseph J Larson, Elizabeth J Atkinson, G Richard Locke, Nicholas J Talley, Yuri A Saito
GOALS: To evaluate agreement of MCM6-13910 with self-report of dairy sensitivity (DS) and lactose hydrogen methane breath test (LHMBT) results in subjects with irritable bowel syndrome (IBS). BACKGROUND: IBS is a functional gastrointestinal disorder with symptoms including abdominal pain, variable bowel habits, and bloating. Adult patients with lactose malabsorption may present with similar symptoms. Patients with lactose malabsorption have a lactase nonpersistent (LNP) phenotype...
June 16, 2018: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/29912648/partial-dietary-inclusion-of-hermetia-illucens-black-soldier-fly-full-fat-prepupae-in-zebrafish-feed-biometric-histological-biochemical-and-molecular-implications
#10
Matteo Zarantoniello, Leonardo Bruni, Basilio Randazzo, Arturo Vargas, Giorgia Gioacchini, Cristina Truzzi, Anna Annibaldi, Paola Riolo, Giuliana Parisi, Gloriana Cardinaletti, Francesca Tulli, Ike Olivotto
Due to minimal environmental impact, compared to most conventional feed commodities, insects deserve a growing attention as candidate ingredients for aquafeeds. This study tested, for the first time during zebrafish larval rearing, the effects of an increasing replacement (0%-25%-50%) of fish meal by black soldier fly (BSF) full-fat prepupae meal. All diets were formulated to be isonitrogenous and isolipidic. A multidisciplinary approach, including biometrics, histology, gas chromatography-mass spectrometry, and molecular analyses, was applied to better understand the biological responses of larval zebrafish to the different partial inclusions of BSF in the feed...
June 18, 2018: Zebrafish
https://www.readbyqxmd.com/read/29912642/investigation-of-the-potential-for-a-simplified-exposure-tool-in-medical-nutrition-setim-to-minimise-exposures-to-sweeteners-in-young-patients-aged-1-3-years-with-pku-and-cmpa
#11
Aaron J O'Sullivan, Cian O'Mahony, Leo Meunier, Nik Loveridge, Aideen I McKevitt
Children with Phenylketonuria (PKU) and severe cow's milk protein allergy (CMPA) consume prescribed, specially formulated, foods for special medical purposes (FSMPs) in addition to having restricted intake of normal foods. These vulnerable patients are exposed to artificial sweeteners from the consumption of a combination of both free and prescribed foods. Young patients with PKU and CMPA aged from 1-3 years have a higher risk of exceeding the acceptable daily intake (ADI) for sweeteners than age-matched healthy children...
June 18, 2018: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/29912638/mycotoxin-contamination-of-sorghum-and-its-contribution-to-human-dietary-exposure-in-four-sub-saharan-countries
#12
Geoffrey Ssepuuya, Christof Van Poucke, Emmanuel Njumbe Ediage, Catherine Mulholland, Angelika Tritscher, Philippe Verger, Mary Kenny, Catherine Bessy, Sarah De Saeger
This research aimed at evaluating the safety, and the type, level and prevalence of mycotoxins in grain sorghum of four sub-Saharan African (SSA) countries (Burkina Faso, Ethiopia, Mali and Sudan). A multi-analyte LC-MS/MS method for quantification of 23 mycotoxins (nivalenol, deoxynivalenol, fusarenon X, neosolaniol, 3-acetyl deoxynivalenol, 15-acetyl deoxynivalenol, diacetoxyscirpenol, roquefortine C, HT-2 toxin, alternariol, T-2 toxin, FB1, FB2, FB3, zearalenone, aflatoxin G1 , aflatoxin G2 , aflatoxin B1 , aflatoxin B2 , sterigmatocystin, OTA, altenuene, alternariol monomethylether) was applied to different sorghum matrices...
June 18, 2018: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/29912604/investigation-of-the-effect-of-dietary-docosahexaenoic-acid-dha-supplementation-on-macular-function-in-subjects-with-autosomal-recessive-stargardt-macular-dystrophy
#13
Ian M MacDonald, Paul A Sieving
PURPOSE: To test the effect of docosahexanoic acid (DHA) dietary supplementation on macular function in patients with Stargardt disease. MATERIALS AND METHODS: A single center, double-masked, randomized placebo-controlled trial of 11 subjects (2 males, 9 females) with Stargardt disease in a crossover design (NCT00060749). Six participants were randomized to two sequences of three month periods of DHA supplementation (2000 mg/day) followed by three months of placebo...
June 18, 2018: Ophthalmic Genetics
https://www.readbyqxmd.com/read/29912570/the-use-of-a-stem-and-leaf-aqueous-extract-of-cissus-quadrangularis-cqr-300-to-reduce-body-fat-and-other-components-of-metabolic-syndrome-in-overweight-participants
#14
Robert Nash, Boris Azantsa, Dieudonne Kuate, Harrinder Singh, Julius Oben
BACKGROUND: Previous work had shown the ability of an aqueous leaf and stem extract of Cissus quandrangularis (300 mg of CQR, CQR-300) to improve components of metabolic syndrome (MS) in overweight individuals. OBJECTIVE: This small pilot study aimed to confirm the efficacy of CQR-300 in reducing the percentage body fat measured using two different methods-bioelectrical impedance assay versus dual-energy X-ray absorptiometry (DEXA). DESIGN: The study was an 8-week double-blind, placebo-controlled pilot trial on 67 individuals who were requested by a dietary counselor to maintain their normal exercise and dietary routines...
June 18, 2018: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/29912430/body-size-and-gastrointestinal-morphology-of-nutria-myocastor-coypus-reared-on-an-extensive-or-intensive-feeding-regime
#15
Robert Glogowski, William Pérez, Marcus Clauss
Although plasticity of growth rates is mainly associated with ectotherm species, it does occur in endotherms as well, but has not been documented systematically for many species. We compared the effect of two common types of feeding systems, differing in energetic value, on body size and gastrointestinal tract morphology in nutrias (Myocastor coypus). A total of 30 extensively (E) fed and 20 intensively (I) fed animals were used in the study. We noted significant effects of age, sex and feeding regime on body weight and length, with one-year-old females attaining 3...
June 15, 2018: Journal of Animal Science
https://www.readbyqxmd.com/read/29912353/nutritional-impact-on-mammary-development-in-pigs-a-review
#16
Chantal Farmer
Milk yield is a crucial component of a sow operation because it is a limiting factor for piglet growth rate. Stimulating mammary development is one avenue that could be used to improve sow milk production. A number of studies have shown that nutrition of gilts or sows during the periods of rapid mammary accretion occurring during prepuberty, gestation, and lactation can affect mammary development. The present review provides an overview of all the information currently published on the subject and Table 1 summarizes the dietary treatments that enhance mammary development in pigs...
June 15, 2018: Journal of Animal Science
https://www.readbyqxmd.com/read/29912268/diet-quality-indices-and-leukocyte-telomere-length-among-healthy-us-adults-data-from-the-national-health-and-nutrition-examination-surveys-nhanes-1999-2002
#17
Cindy W Leung, Teresa T Fung, Claire T McEvoy, Jue Lin, Elissa S Epel
Aging is the biggest risk factor for the development of chronic diseases. Telomere length may represent one important mechanism by which dietary intake influences age-related diseases; however, it is unknown which diet pattern is most strongly related to telomere length. We compared the relations between four evidence-based diet quality indices and leukocyte telomere length in a nationally representative sample of healthy adults, and the extent to which these associations differ between men and women. Data came from 4,758 adults, aged 20-65 years, with no prior diagnosis of major chronic disease, from the 1999-2002 National Health and Nutrition Examination Surveys (NHANES)...
June 15, 2018: American Journal of Epidemiology
https://www.readbyqxmd.com/read/29912245/dietary-supplemental-kluyveromyces-marxianus-alters-the-serum-metabolite-profile-in-broiler-chickens
#18
Weiwei Wang, Zhui Li, Liping Gan, Hao Fan, Yuming Guo
Metabolomics is used to evaluate the bioavailability of food components, as well as to validate the metabolic changes associated with food consumption. This study was conducted to investigate the effects of the dietary supplement Kluyveromyces marxianus on the serum metabolite profile in broiler chickens. A total of 240 1-d-old broilers were divided into 2 groups with 8 replicates. Birds were fed basal diets without or with K. marxianus supplementation (5 × 1010 CFU kg-1 of diet). Serum samples were collected on d 21 and were analyzed by high-performance liquid chromatography with quadrupole time-of flight/mass spectrometry...
June 18, 2018: Food & Function
https://www.readbyqxmd.com/read/29912173/deep-artificial-neural-networks-for-the-diagnostic-of-caries-using-socioeconomic-and-nutritional-features-as-determinants-data-from-nhanes-2013%C3%A2-2014
#19
Laura A Zanella-Calzada, Carlos E Galván-Tejada, Nubia M Chávez-Lamas, Jesús Rivas-Gutierrez, Rafael Magallanes-Quintanar, Jose M Celaya-Padilla, Jorge I Galván-Tejada, Hamurabi Gamboa-Rosales
Oral health represents an essential component in the quality of life of people, being a determinant factor in general health since it may affect the risk of suffering other conditions, such as chronic diseases. Oral diseases have become one of the main public health problems, where dental caries is the condition that most affects oral health worldwide, occurring in about 90% of the global population. This condition has been considered a challenge because of its high prevalence, besides being a chronic but preventable disease which can be caused depending on the consumption of certain nutritional elements interacting simultaneously with different factors, such as socioeconomic factors...
June 18, 2018: Bioengineering
https://www.readbyqxmd.com/read/29911516/sex-consideration-in-diet-biomarker-related-indices-a-systematic-review
#20
Sihan Song, Sejin Kim, Jung Eun Lee
OBJECTIVE: An index of biomarkers derived from dietary factors (diet-biomarker-related index) identifies foods and nutrients that encompass physiological potentials and provides scientific evidence for dietary patterns that increase the risk of disease associated with specific biomarkers. Although men and women have different dietary patterns and physiological characteristics, sex is not often considered when investigators develop a diet-biomarker-related index. We aimed to review whether epidemiological studies developed diet-biomarker-related indices in a sex-specific way...
June 18, 2018: Public Health Nutrition
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