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Elder DE

Larissa de Carli Coppetti, Nara Marilene Oliveira Girardon-Perlini, Rafaela Andolhe, Maria Gaby Rivero de Gutiérrez, Steffani Nikoli Dapper, Fernanda Duarte Siqueira
OBJECTIVE: To analyze the association between the caring ability of family caregivers of patients on cancer treatment with the demographic and clinical characteristics of the patients, as well as the sociodemographic characteristics of the caregivers and of the care provided. METHODS: A cross-sectional study was conducted with 132 family caregivers of patients on cancer treatment whose data were collected through the Brazilian version of the Caring Ability Inventory and questionnaires characterizing patients, caregivers and the care provided...
October 11, 2018: Revista Latino-americana de Enfermagem
Rita Ostan, Giulia Guidarelli, Enrico Giampieri, Catia Lanzarini, Agnes A M Berendsen, Olga Januszko, Amy Jennings, Noëlle Lyon, Elodie Caumon, Rachel Gillings, Ewa Sicinska, Nathalie Meunier, Edith J M Feskens, Barbara Pietruszka, Lisette C P G M de Groot, Susan Fairweather-Tait, Miriam Capri, Claudio Franceschi, Aurelia Santoro
Methods for measuring diet composition and quantifying nutrient intake with sufficient validity are essential to study the association between nutrition and health outcomes and risk of diseases. 7-day food records provides a quantification of food actually and currently consumed and is interesting for its use in intervention studies to monitor diet in a short-term period and to guide participants toward changing their intakes. The objective of this study is to analyze the correlation/association between the daily intake of selected nutrients (collected by a 7-day food records plus a mineral/vitamin supplementation questionnaire) and estimates of energy expenditure as well as blood and urine biomarkers of dietary intakes in 1,140 healthy elderly subjects (65-79 years) at baseline of the NU-AGE intervention study (NCT01754012, clinicaltrials...
2018: Frontiers in Physiology
Hanneke J A Smaling, Karlijn J Joling, Peter M van de Ven, Judith E Bosmans, Joyce Simard, Ladislav Volicer, Wilco P Achterberg, Anneke L Francke, Jenny T van der Steen
INTRODUCTION: Quality of life of people with advanced dementia living in nursing homes is often suboptimal. Family caregivers can feel frustrated with limited contact with their relatives, which results in visits that are perceived as stressful and not very meaningful. Few psychosocial interventions are specifically developed for people with advanced dementia, and actively involve family caregivers or volunteers. Also, interventions usually stop when it becomes difficult for people to participate...
October 15, 2018: BMJ Open
Massimo Ralli, Antonio Greco, Marco De Vincentiis, Adam Sheppard, Giampietro Cappelli, Ilaria Neri, Richard Salvi
PURPOSE: One of the most common complaints among the elderly is the inability to understand speech in noisy environments. In many cases, these deficits are due to age-related hearing loss; however, some of the elderly that have difficulty hearing in noise have clinically normal pure-tone thresholds. While speech in noise testing is informative, it fails to identify specific frequencies responsible for the speech processing deficit. Auditory neuropathy patients and animal models of hidden hearing loss suggest that tone-in-noise thresholds may provide frequency specific information for those patients who express difficulty, but have normal thresholds in quiet...
September 17, 2018: American Journal of Otolaryngology
Melissa Bersanelli, Diana Giannarelli, Paola Castrignanò, Giuseppe Fornarini, Stefano Panni, Francesca Mazzoni, Marcello Tiseo, Sabrina Rossetti, Elisabetta Gambale, Ernesto Rossi, Anselmo Papa, Alessio Cortellini, Cristian Lolli, Raffaele Ratta, Maria Michiara, Michele Milella, Emmanuele De Luca, Mariella Sorarù, Claudia Mucciarini, Francesco Atzori, Giuseppe L Banna, Leonardo La Torre, Maria G Vitale, Francesco Massari, Sara E Rebuzzi, Gaetano Facchini, Giovanni Schinzari, Silverio Tomao, Simona Bui, Vanja Vaccaro, Giuseppe Procopio, Ugo De Giorgi, Matteo Santoni, Corrado Ficorella, Roberto Sabbatini, Antonio Maestri, Clara Natoli, Michele De Tursi, Massimo Di Maio, Elena Rapacchi, Annagrazia Pireddu, Teodoro Sava, Helga Lipari, Francesca Comito, Elena Verzoni, Francesco Leonardi, Sebastiano Buti
AIM: Considering the unmet need for the counseling of cancer patients treated with immune checkpoint inhibitors (CKI) about influenza vaccination, an explorative study was planned to assess flu vaccine efficacy in this population. METHODS: INVIDIa was a retrospective, multicenter study, enrolling consecutive advanced cancer outpatients receiving CKI during the influenza season 2016-2017. RESULTS: Of 300 patients, 79 received flu vaccine. The incidence of influenza syndrome was 24...
October 2018: Immunotherapy
Werner Keenswijk, Ann Raes, Marieke de Clerck, Johan Vande Walle
Shigatoxin-associated hemolytic uremic syndrome (STEC-HUS) is associated with significant mortality and morbidity. Case fatalities are often associated with severe neurological involvement in children and advanced age in adults but specific treatment is currently unavailable. Plasma exchange (PE) could theoretically enable removal of Shigatoxins, pro-inflammatory cytokines and prothrombotic factors and has been used in deteriorating patients with STEC-HUS but the efficacy remains uncertain. In order to assess efficacy of PE in STEC-HUS a literature review was performed...
October 15, 2018: Therapeutic Apheresis and Dialysis
Claudio Vicini, Andrea De Vito, Giannicola Iannella, Riccardo Gobbi, Ruggero Massimo Corso, Filippo Montevecchi, Antonella Polimeni, Marco De Vincentiis, Giuseppe Meccariello, Giovanni D'agostino, Giovanni Cammaroto, Francesco Stomeo, Giuseppe Magliulo
PURPOSE: To evaluate, using drug-induced sleep endoscopy (DISE), sites of upper airway obstruction and pattern of collapse in patients over 65 years old affected by obstructive sleep apnea. To compare sites and pattern of collapse of elderly patients with a group of patients younger than 65 years. METHODS: A group of 55 patients aged over 65 years were enrolled in this prospective study. Fifty patients under 65 years old were collected in the control group. Polysomnographic data and clinical parameters such as the daytime sleepiness, and body mass index were evaluated for both groups of patients...
October 13, 2018: European Archives of Oto-rhino-laryngology
Josep Franch-Nadal, Fermín García-Gollarte, Alfonso Pérez Del Molino, María L Orera-Peña, Marta Rodríguez de Miguel, Malena Melogno-Klinkas, Héctor D de Paz, Susana Aceituno, Patricia Rodríguez-Fortúnez
BACKGROUND: Management of elderly patients with type 2 diabetes mellitus (T2DM) is complex due to their age-related conditions. Several clinical guidelines provide specific recommendations for management of these patients but little is known about their implementation in clinical practice. OBJECTIVE: To describe physician and community pharmacist perceptions and routine clinical practice in the management of elderly T2DM patients. METHODS: Cross-sectional study...
October 12, 2018: Clinical Drug Investigation
Alejandra Andrea Roman Lay, Carla Ferreira do Nascimento, Yeda Aparecida de Oliveira Duarte, Alexandre Dias Porto Chiavegatto Filho
OBJECTIVE: To conduct a survival analysis according to age at natural menopause (NM) in a representative sample of elderly women from the municipality of São Paulo, Brazil. STUDY DESIGN: We analyzed data from the Health, Well-Being and Aging study (SABE), a cohort that started in 2000. Mortality data up to September 2016 were obtained by linkage from the Program for Mortality Information of São Paulo (PRO-AIM). MAIN OUTCOME MEASURES: We used Cox regression to analyze all-cause and cause-specific mortality rates for cardiovascular diseases, respiratory diseases and cancer, according to age at menopause, categorized as <40, 41-44, 45-49, 50-54 (reference) and ≥55...
November 2018: Maturitas
João L Geirinhas, Ricardo M Trigo, Renata Libonati, Lucas C O Castro, Pedro M Sousa, Caio A S Coelho, Leonardo F Peres, Mônica de Avelar F M Magalhães
Global temperatures have increased considerably over the last decades, directly impacting the number, intensity and duration of extreme events such as heat waves. Climate model projections accounting for anthropogenic factors indicate that deadly mega-heat waves are likely to become more frequent in the future. Although the atmospheric features and social-economic related impacts of heat waves have already been documented in various regions around the world, for other highly populated regions, such as the Metropolitan Region of Rio de Janeiro (MRRJ), a similar objective assessment is still needed...
February 10, 2019: Science of the Total Environment
Carla Helena Augustin Schwanke, Thamiris De Cristho Dorneles, Raquel Milani El Kik
INTRODUCTION: the measurement of the adductor pollicis muscle thickness (APMT) has been investigated as an anthropometric parameter; however, there are few studies related to hospitalized elderly patients. OBJECTIVE: to analyze the association between APMT and nutritional parameters in hospitalized elderly patients. METHOD: cross-sectional study made in 331 hospitalized elderly patients. The following variables have been assessed: APMT, Mini Nutritional Assessment® (MNA®), body mass index (BMI), arm circumference (AC), calf circumference (CC) and handgrip strength (HGS)...
October 5, 2018: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
Esther M C van Leijsen, Jonathan Tay, Ingeborg W M van Uden, Eline C M Kooijmans, Mayra I Bergkamp, Helena M van der Holst, Mohsen Ghafoorian, Bram Platel, David G Norris, Roy P C Kessels, Hugh S Markus, Anil M Tuladhar, Frank-Erik de Leeuw
BACKGROUND: White matter hyperintensities (WMH) constitute the visible spectrum of cerebral small vessel disease (SVD) markers and are associated with cognitive decline, although they do not fully account for memory decline observed in individuals with SVD. We hypothesize that WMH might exert their effect on memory decline indirectly by affecting remote brain structures such as the hippocampus. We investigated the temporal interactions between WMH, hippocampal atrophy and memory decline in older adults with SVD...
October 11, 2018: Hippocampus
Fabio Rondelli, Michele De Rosa, Paolo Stella, Marcello Boni, Graziano Ceccarelli, Ruben Balzarotti, Andrea Polistena, Alessandro Sanguinetti, Walter Bugiantella, Nicola Avenia
BACKGROUND: Acute appendicitis is a common acute surgical abdominal condition and despite that most of cases are observed in children and young adults, its occurrence in the elderly seems to be increasing, with a higher risk of perforation. The aim of this study was to evaluate the surgical outcomes following appendectomy for acute appendicitis in the elderly, making a comparison between perforated and nonperforated groups regarding operative time, hospital stay and postoperative complications...
October 9, 2018: Minerva Chirurgica
J Santabárbara, R Lopez-Anton, C de la Cámara, E Lobo, P Gracia-García, B Villagrasa, J Bueno-Notivol, G Marcos, A Lobo
OBJECTIVE: To evaluate whether clinically significant anxiety is an independent risk factor for dementia, taking into account both depression among potentially confounding factors and the competing risk of death. METHOD: During the Zaragoza Dementia and Depression (ZARADEMP) study, a random sample of community dwellers aged 55 years or older was assessed (n = 4803), and a two-wave, 4.5-year follow-up was completed. Geriatric Mental State (GMS)-AGECAT criteria were used to diagnose anxiety and DSM-IV criteria were applied to diagnose incident dementia...
October 10, 2018: Acta Psychiatrica Scandinavica
E Biver, J Pepe, A de Sire, T Chevalley, S Ferrari
An exploratory study in elderly women and men from the Geneva Retirees Cohort indicates that low-frequency quantitative ultrasound measurement at the radius captures aBMD, bone size, and cortical tissue mineral density and might be used for screening purposes prior to DXA to evaluate fracture risk. INTRODUCTION: The contribution of distal radius bone mineral density (BMD) and cortical microstructure to fracture risk has recently been demonstrated. In this exploratory study, we investigated whether low-frequency quantitative ultrasound measurement at the distal radius may capture the peripheral determinants of bone fragility assessed with dual-energy X-ray absorptiometry (DXA) and high-resolution peripheral quantitative computed tomography (HR-pQCT)...
October 10, 2018: Osteoporosis International
Michelle Lima Garcez, Carlos Alberto de Carvalho, Francielle Mina, Tatiani Bellettini-Santos, Gustavo Luis Schiavo, Sabrina da Silva, Ana Carolina Brunatto Falchetti Campos, Roger Varela, Samira da Silva Valvassori, Adriani Paganini Damiani, Luiza Martins Longaretti, Vanessa Moraes de Andrade, Josiane Budni
Aging is a complex biological process. Epigenetic alterations have been related to both aging and memory decline. Included amongst these alterations is histone acetylation, which may play a crucial role in aging. Thus, the aims of the present study were to standardize the animal model of d-gal, and to evaluate the effects caused by sodium butyrate (SB), which is a histone deacetylase inhibitor on; memory, the modulation of histone deacetylases (HDACs) and also DNA damage in 2, 6 or 16-month-old Wistar rats which were subjected to administrations of d-galactose (d-gal)...
October 7, 2018: Experimental Gerontology
Rodrigo Santos de Queiroz, Luciano Magno de Almeida Faria, José Ailton Oliveira Carneiro, Raildo da Silva Coqueiro, Marcos Henrique Fernandes
OBJECTIVES: The goal was to identify predictors of poor-quality spirometry in community-dwelling older adults and their respective cutoffs. METHODS: This was a cross-sectional population-based study involving 245 elderly subjects (age≥60 years). The spirometric data were categorized as good or poor quality, and cognitive status was assessed using an adapted version (scaled to have a maximum of 19 points) of the Mini-Mental State Examination. Multivariate analysis was used to assess the association between poor-quality spirometry and sociodemographic, behavioral and health characteristics...
October 8, 2018: Clinics
Bruno Oliveira de Figueiredo Brito, Antônio Luiz Pinho Ribeiro
Since the initial descriptions of Chagas cardiomyopathy (ChCM), the electrocardiography has played a key role in patient evaluations. The diagnostic criterion of chronic ChCM is the presence of characteristic electrocardiographic (ECG) abnormalities in seropositive individuals, regardless of the presence of symptoms. However, these ECG abnormalities are rarely specific to ChCM and, particularly among the elderly, can be caused by other simultaneous cardiomyopathies. ECG abnormalities can predict the occurrence of heart failure, stroke, and even death...
September 2018: Revista da Sociedade Brasileira de Medicina Tropical
Monalisa Claudia Maria da Silva, Alexander Moreira-Almeida, Edna Aparecida Barbosa de Castro
OBJECTIVE: To investigate the forms of coping used to relieve tensions by elderly caregivers of elderly relatives and to know the type of support they receive from the Primary Health Care service at home. METHOD: A qualitative study with a theoretical-methodological contribution of Grounded Theory, carried out with 10 elderly caregivers interviewed between August 2014 and January 2015. RESULTS: Participants use primarily religious coping to deal with adverse situations that arise in their lives; they attribute to the sacred the strength to continue to age and care for another elderly person at home...
September 2018: Revista Brasileira de Enfermagem
Gabrielle Ferreira Melo Marques, Danielle Mayara Rodrigues Palhão de Rezende, Iara Pereira da Silva, Priscila Carolina de Souza, Suzi Rosa Miziara Barbosa, Ramon Moraes Penha, Camila Guimarães Polisel
OBJECTIVE: To identify polypharmacy and potentially inappropriate medications (PIM) for elder people with chronic health situations and its implications for gerontological nursing. METHOD: Descriptive and transversal study, conducted from March to September 2016 by pharmaceutical residents in the clinic of Endocrinology of a hospital in Mid-West region of Brazil. RESULTS: 44 elder people with an average age of 69.5 (± 6.79) years old had their assessed prescriptions...
September 2018: Revista Brasileira de Enfermagem
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