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Elder DE

Lauren Power, Marian A E de van der Schueren, Susanne Leij-Halfwerk, Jürgen Bauer, Michelle Clarke, Marjolein Visser, Dorothee Volkert, Laura Bardon, Eileen Gibney, Clare A Corish
RATIONALE: Many malnutrition screening tools are used to screen for risk of malnutrition in older adults. An aim of the Joint Programming Initiative (JPI) 'A Healthy Diet for a Healthy Life' (HDHL) MalNutrition in the ELderly Knowledge hub (MaNuEL) is to devise recommendations on the best tools to screen for risk of malnutrition in older adults in community and healthcare settings across Europe. The aim of this paper was to develop and apply a scoring system to rate malnutrition screening tools...
July 27, 2018: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
Maria Papageorgiou, Liz Wells, Courtney Williams, Kay L M White, Barbara De Santis, Yunru Liu, Francesca Debegnach, Brunella Miano, Giorgio Moretti, Stephanie Greentham, Carlo Brera, Stephen L Atkin, Laura J Hardie, Thozhukat Sathyapalan
Deoxynivalenol (DON) is a Fusarium toxin, to which humans are frequently exposed via diet. Although the elderly are speculated to be sensitive to the toxic effects of DON as a result of age-related conditions, disease and altered DON metabolism, there is lack of available data on DON biomarkers in this age group. This study characterised urinary DON concentrations and its metabolites in elderly aged ≥65years (n = 20) residing in Hull, UK. Morning urinary specimens were collected over two consecutive days together with food records to assess dietary intake over a 24h-period prior to each urinary collection...
August 17, 2018: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
Arnon P Kater, Marinus H J van Oers, Yvette van Norden, Lina van der Straten, Julia Driessen, Ward F M Posthuma, Martinus Schipperus, Martine E D Chamuleau, Marcel Nijland, Jeanette K Doorduijn, Michel Van Gelder, Mels Hoogendoorn, Francien De Croon, Shulamiet Wittebol, J Martijn Kerst, Erik W A Marijt, Reinier A P Raymakers, Martijn R Schaafsma, Johan A Dobber, Sabina A Kersting, Mark-David Levin
BACKGROUND: Lenalidomide (Len) has been proven effective both as monotherapy and in combination with rituximab for the treatment of chronic lymphocytic leukemia (CLL). Len has shown a distinct and more difficult to manage toxicity profile in the context of CLL, potentially hampering combination treatment with this drug. METHODS: In 1st-line CLL elderly and fludarabine, cyclophosphamide, rituximab (FCR) unfit patients, we conducted a phase 1-2 study to evaluate efficacy and safety of 6 cycles of chlorambucil (7mg/m2 on days 1-7), rituximab (375mg/m2 cycle 1 and 500mg/m2 cycle 2-6) and individual dosed Len (started on day 9 of cycle 1 2...
August 16, 2018: Haematologica
Eiji Ichimoto, Adam Arnofsky, Michael Wilderman, Richard Goldweit, Joseph De Gregorio
Background: Transcatheter aortic valve replacement (TAVR) has been performed for many elderly patients with severe aortic stenosis (AS). The SAPIEN 3 is one of the latest balloon-expandable prosthesis. This study aimed to investigate the early clinical outcomes after TAVR using the SAPIEN 3 in nonagenarians. Methods: A total of 97 consecutive patients underwent TAVR for severe AS between December 2015 and December 2016. Of these, 85 consecutive patients who underwent TAVR using the SAPIEN 3 were included...
June 2018: Journal of Geriatric Cardiology: JGC
Marta Jeruszka-Bielak, Anna Kollajtis-Dolowy, Aurelia Santoro, Rita Ostan, Agnes A M Berendsen, Amy Jennings, Nathalie Meunier, Anna Marseglia, Elodie Caumon, Rachel Gillings, Lisette C P G M de Groot, Claudio Franceschi, Sophie Hieke, Barbara Pietruszka
Background: Nutrition-related knowledge (NRK) and nutrition-related attitudes (NRAs) are necessary for dietary changes toward healthier dietary patterns. In turn, healthier dietary patterns can be beneficial in maintaining health of older adults. Therefore, the aim of this cross-sectional study was to investigate whether NRK and NRAs were associated with lifestyle and health features among older adults (65+ years) from five European countries (France, Italy, Poland, the Netherlands and United Kingdom). Methods: Within the European project NU-AGE, 1,144 healthy elderly volunteers (65-79 years) were randomly assigned to two groups: intervention (NU-AGE diet) or control...
2018: Frontiers in Physiology
Maria Lucia Caruso, Elisabetta Cavalcanti, Antonia Ignazzi, Giulio Lantone, Francesco De Michele
No abstract text is available yet for this article.
August 13, 2018: Inflammatory Bowel Diseases
Max W de Graaf, Inge H F Reininga, Klaus W Wendt, Erik Heineman, Mostafa El Moumni
Background: The Short Musculoskeletal Function Assessment (SMFA) is a widely used patient-reported outcome measure, originally having 2 elements of outcome: the function index and the bother index. In multiple studies, it has been argued that the SMFA should be scored using 3, 4, or 6 subscales instead. Hence, there is inconsistency about the number of underlying dimensions of the SMFA. Objective: The aim of this study was to evaluate the structural validity of the various proposed subscale configurations of the SMFA in a broad range of Dutch patients with injuries...
August 9, 2018: Physical Therapy
Vânia Silva Macedo Orsano, Wilson Max Almeida Monteiro de Moraes, Nuno Manuel Frade de Sousa, Felipe Carmo de Moura, Ramires Alsamir Tibana, Alessandro de Oliveira Silva, Silvana Schwerz Funghetto, Brad J Schoenfeld, Jonato Prestes
Objectives: The aim of the present study was to compare the acute effects of traditional resistance training (RT) versus high velocity RT (HVRT) on metabolic, cardiovascular, and psychophysiological responses in elderly hypertensive women. Methods: Fifteen elderly women (mean age ± standard deviation, 67.1±6.9 years) classified as having hypertension stage 1 or 2 were randomly allocated to complete traditional RT or HVRT; 1 week later, subjects allocated to RT completed the HVRT session and vice-versa...
2018: Clinical Interventions in Aging
Elena Chiappini, Federica Inturrisi, Elisa Orlandini, Maurizio de Martino, Chiara de Waure
BACKGROUND: Invasive bacterial diseases (IBD) are a serious cause of hospitalization, sequelae and mortality. Albeit a low incidence, an increase in cases due to H. influenzae was registered in the past 4 years and, in the Tuscany region, an excess of cases due to N. meningitidis since 2015 is alarming. The purpose of this study is to deepen the knowledge of IBD epidemiology in Tuscany with particular attention to temporal trends. METHODS: Tuscan residents hospitalized for IBD from January 1st 2000 to March 18th 2016 were selected from the regional hospital discharge database based on ICD-9-CM codes...
August 13, 2018: BMC Infectious Diseases
Emma Säfström, Tiny Jaarsma, Anna Strömberg
BACKGROUND: The period after hospitalization due to deteriorated heart failure (HF) is characterized as a time of high generalized risk. The transition from hospital to home is often problematic due to insufficient coordination of care, leading to a fragmentation of care rather than a seamless continuum of care. The aim was to describe health and community care utilization prior to and 30 days after hospitalization, and the continuity of care in patients hospitalized due to de novo or deteriorated HF from the patients' perspective and from a medical chart review...
August 13, 2018: BMC Geriatrics
Roberta Lizio, Claudio Babiloni, Claudio Del Percio, Antonia Losurdo, Lucia Vernò, Marina De Tommaso, Anna Montemurno, Giuseppe Dalfino, Pietro Cirillo, Andrea Soricelli, Raffaele Ferri, Giuseppe Noce, Maria Teresa Pascarelli, Valentina Catania, Flavio Nobili, Francesco Famá, Francesco Orzi, Franco Giubilei, Carla Buttinelli, A Ivano Triggiani, Giovanni B Frisoni, Anna Maria Scisci, Nicola Mastrofilippo, Deni Aldo Procaccini, Loreto Gesualdo
This study tested whether resting state alpha rhythms (8-13 Hz) may characterize mild cognitive impairment due to Alzheimer's disease (ADMCI) compared with MCI due to chronic kidney disease (CKDMCI). Clinical and resting state eyes-closed electroencephalographic (rsEEG) rhythms from 40 ADMCI, 29 CKDMCI, and 45 cognitively normal elderly (Nold) subjects were available in a national archive. Age, gender, and education were matched in the three groups, and Mini-Mental State Evaluation (MMSE) score was paired in the ADMCI and CKDMCI groups...
August 3, 2018: Journal of Alzheimer's Disease: JAD
M Baré, L Mora, N Torà, M J Gil, I Barrio, P Collera, D Suárez, M Redondo, A Escobar, N Fernández de Larrea, J M Quintana
BACKGROUND: The aim of this study was to assess factors associated with outcomes after surgery for colorectal cancer and to design and internally validate a simple score for predicting perioperative mortality. METHODS: Patients undergoing surgery for primary invasive colorectal cancer in 22 centres in Spain between June 2010 and December 2012 were included. Clinical variables up to 30 days were collected prospectively. Multiple logistic regression techniques were applied and a risk score was developed...
August 13, 2018: British Journal of Surgery
Josefina Bertoli, Juliano Dal Pupo, Marco A Vaz, Daniele Detanico, Grazieli M Biduski, Cíntia de la Rocha Freitas
This study aimed to analyze the effects of Mat Pilates on isokinetic torque of the lower limbs in elderly women. Fourteen elderly women (Age 62 ± 3 yr) participated in 12 weeks of Mat Pilates training (60-min sessions, 3 times per week). Repetitions increased every 4 weeks and the difficulty of exercises progressed from beginner to intermediate and advanced. Peak torque was assessed before (week -4 and week 0, considered as a control period) and after 6 and 12 weeks of a periodized Mat Pilates intervention...
July 2018: Journal of Bodywork and Movement Therapies
Maria das Graças Bastos Licurci, Alessandra de Almeida Fagundes, Emilia Angela Lo Schiavo Arisawa
BACKGROUND: Whole body vibration (WBV) has been widely used as a modality for physical activity. In fact, WBV has been used for physical rehabilitation, and to improve muscle performance; but there is little information about its effects on heart rate variability (HRV). AIM: The aim of this study was to evaluate the effect of vibration on HRV of the elderly using the vibratory platform. METHODS: Eleven older adults (7 men, 4 women), aged between 60 and 75 years, were subjected to WBV...
July 2018: Journal of Bodywork and Movement Therapies
Lucas Bet da Rosa Orssatto, Bruno Monteiro de Moura, Raphael Luiz Sakugawa, Regis Radaelli, Fernando Diefenthaeler
The aim of this study was to investigate whether 12 weeks of leg press strength training exercise could affect the conventional and functional hamstring:quadriceps ratios in the elderly. Twelve elderly participants were submitted to a 12 week progressive training protocol (two sessions/week) using a 45° leg press exercise. A significant increase in the one repetition maximum was observed after 4, 8, and 12 weeks (p = 0.001, p < 0.001, and p < 0.001, respectively) compared to week 0 and after 8 (p = 0...
July 2018: Journal of Bodywork and Movement Therapies
Ivan Aprahamian, Claudia Kimie Suemoto, Sumika Mori Lin, Alaise Silva Santos de Siqueira, Marina Maria Biella, Brian Alvarez Ribeiro de Melo, Wilson Jacob-Filho
ABSTRACTObjectives:The aim of the present study was to evaluate the association between depression and SSRI monotherapy and frailty both baseline and prospectively in older adults. DESIGN: Prospective cohort study, 12-month follow-up. SETTING: Geriatric outpatient clinic in São Paulo, Brazil. PARTICIPANTS: A total of 811 elderly adults aged 60 or older. MEASUREMENTS: Depression was diagnosed as follows: (1) a diagnosis of major depression disorder (MDD) according to DSM-5; or (2) an incomplete diagnosis of MDD, referred to as minor or subsyndromic depression, plus Geriatric Depression Scale 15-itens ≥ 6 points, and social or functional impairment secondary to depressive symptoms and observed by relatives...
August 13, 2018: International Psychogeriatrics
Marlies Mulder, Jessica C Kiefte-de Jong, Wil Hf Goessens, Herman de Visser, M Arfan Ikram, Annelies Verbon, Bruno H Stricker
OBJECTIVES: There is an ongoing debate to which extent antimicrobial resistance (AMR) can be transmitted from animals to humans via the consumption of animal products. Because epidemiological data on the role of diet on AMR in humans are lacking, we investigated this association between diet and AMR to different antimicrobial drugs in E. coli in urinary tract infections (UTIs). METHODS: Susceptibility of E.coli in urinary cultures and information on diet (with food frequency questionnaires) were obtained from participants of the Rotterdam study, a population-based prospective cohort study...
August 9, 2018: Clinical Microbiology and Infection
Arritxu Etxeberria, Josune Iribar, Rafael Rotaeche, Kalliopi Vrotsou, Iosu Barral
BACKGROUND AND OBJECTIVE: Several interventions have been shown to reduce polypharmacy and potentially inappropriate prescription (PIP). The objective of the study was to evaluate the number of drugs and PIP before and after an educational intervention with the Primary Care physician (PCP), with electronic identification of PIP and structured medication review, in elderly patients with excessive polypharmacy (≥10 drugs). MATERIAL AND METHODS: A before-after intervention study was conducted in the Gipuzkoa district of Osakidetza (Basque Country Health System), in a random sample of patients older than 80 years taking ≥ 10 drugs, and whose PCP attended training sessions...
August 7, 2018: Revista Española de Geriatría y Gerontología
F Potier, J-M Degryse, G Aubouy, S Henrard, B Bihin, F Debacq-Chainiaux, H Martens, M de Saint-Hubert
BACKGROUND: Evidence suggests that providing care for a disabled elderly person may have implications for the caregiver's own health (decreased immunity, hypertension, and depression). OBJECTIVE: Explore if older spousal caregivers are at greater risks of frailty compared to older people without a load of care. DESIGN: Case-control study. SETTING: Participants were assessed at home in Wallonia, Belgium. PARTICIPANTS: Cases: community-dwelling spousal caregivers of older patients, recruited mainly by the geriatric outpatient clinic...
2018: Journal of Frailty & Aging
Fernanda Rossi Paolillo, Vicente Silva Mattos, André Orlandi de Oliveira, Francisco Eduardo Gontijo Guimarães, Vanderlei Salvador Bagnato, Jarbas Caiado de Castro Neto
Diabetes is a complex metabolic disease and has chronic complications. It has been considered a serious public health problem. The aim of the current study was to evaluate skin glycated proteins through fluorescence and Raman techniques. One hundred subjects were invited to participate in the study. Six volunteers did not attend due to exclusion criteria or a change of mind about participating. Therefore, ninety four volunteers were grouped according to age range (20 to 80 years), health condition (non-diabetic, with insulin resistance (IR) and/or diabetic) and Fitzpatrick skin type (I to VI)...
August 9, 2018: Journal of Biophotonics
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