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https://www.readbyqxmd.com/read/30537164/developmental-defects-of-enamel-in-the-deciduous-incisors-of-infants-born-preterm-prospective-cohort
#1
Andréa Araujo de Oliveira Cortines, Patrícia Corrêa-Faria, Liselotte Paulsson, Paulo Sucasas Costa, Luciane Rezende Costa
OBJECTIVE: Developmental defects of enamel (DDE) in preterm infants still require clarification and may favour dental caries, lower food intake, and greater difficulty with weight-height gain. We evaluated factors associated with DDE in preterm infants. SUBJECTS AND METHODS: In this prospective cohort study, we monitored 54 prematurely born infants from birth to 24 months of age. Trained and calibrated dentists examined the oral cavity of these children to identify and categorize DDE...
December 7, 2018: Oral Diseases
https://www.readbyqxmd.com/read/30533532/reactive-oxygen-species-biomarkers-of-microvascular-maturation-and-alveolarization-and-antioxidants-in-oxidative-lung-injury
#2
Arwin M Valencia, Maria A Abrantes, Jamal Hasan, Jacob V Aranda, Kay D Beharry
The lungs of extremely low gestational age neonates (ELGANs) are deficient in pulmonary surfactant and are incapable of efficient gas exchange necessary for successful transition from a hypoxic intrauterine environment to ambient air. To improve gas exchange and survival, ELGANs often receive supplemental oxygen with mechanical ventilation which disrupts normal lung developmental processes, including microvascular maturation and alveolarization. Factors that regulate these developmental processes include vascular endothelial growth factor and matrix metalloproteinases, both of which are influenced by generation of oxygen byproducts, or reactive oxygen species (ROS)...
November 2018: Reactive Oxygen Species (Apex, N.C.)
https://www.readbyqxmd.com/read/30528759/a-comparison-of-developmental-outcomes-of-adolescent-neonatal-intensive-care-unit-survivors-born-with-a-congenital-heart-defect-or-born-preterm
#3
Kaitlyn Easson, Noémi Dahan-Oliel, Charles Rohlicek, Sossy Sahakian, Marie Brossard-Racine, Barbara Mazer, Patricia Riley, Désirée B Maltais, Line Nadeau, Sean Hatzigeorgiou, Norbert Schmitz, Annette Majnemer
OBJECTIVE: To compare cognitive, motor, behavioral, and functional outcomes of adolescents born with a congenital heart defect (CHD) and adolescents born preterm. STUDY DESIGN: Adolescents (11-19 years old) born with a CHD requiring open-heart surgery during infancy (n = 80) or born preterm ≤29 weeks of gestational age (n = 128) between 1991 and 1999 underwent a cross-sectional evaluation of cognitive (Leiter International Performance Scale-Revised), motor (Movement Assessment Battery for Children-II), behavioral (Strengths and Difficulties Questionnaire), and functional (Vineland Adaptive Behavior Scale-II) outcomes...
December 6, 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/30508225/specialist-health-care-services-use-in-a-european-cohort-of-infants-born-very-preterm
#4
Anna-Veera Seppänen, Florence Bodeau-Livinec, Elaine M Boyle, Anna-Karin Edstedt-Bonamy, Marina Cuttini, Liis Toome, Rolf F Maier, Eva Cloet, Corine Koopman-Esseboom, Pernille Pedersen, Janusz Gadzinowski, Henrique Barros, Jennifer Zeitlin
AIM: Children born very preterm require additional specialist care because of the health and developmental risks associated with preterm birth, but information on their health service use is sparse. We sought to describe the use of specialist services by children born very preterm in Europe. METHOD: We analysed data from the multi-regional, population-based Effective Perinatal Intensive Care in Europe (EPICE) cohort of births before 32 weeks' gestation in 11 European countries...
December 3, 2018: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/30505940/effects-of-bronchopulmonary-dysplasia-on-swallow-breath-interaction-and-phase-of-respiration-with-swallow-during-non-nutritive-suck
#5
Eric W Reynolds, Debbie Grider, Rhonda Caldwell, Gilson Capilouto, Abhijit Patwardhan, Richard Charnigo
Objectives: The objective of this study is to describe swallow:breath interaction (SwBr) and phase of respiration incident to swallow (POR) during non-nutritive suck in infants with bronchopulmonary dysplasia and determine if speech-language intervention can modify the characteristics of non-nutritive suck in these infants. Methods: Logistic regression models were used to describe SwBr and POR in 16 low-risk preterm (LRP) infants and 43 infants with bronchopulmonary dysplasia...
September 2018: Journal of Nature and Science
https://www.readbyqxmd.com/read/30502314/health-physical-growth-and-neurodevelopmental-outcomes-in-preterm-infants-of-women-with-hypertensive-disorders-of-pregnancy
#6
Forgive Avorgbedor, Susan Silva, Elizabeth Merwin, James A Blumenthal, Diane Holditch-Davis
OBJECTIVE: To compare the health, physical growth, and developmental outcomes in preterm infants of women with and without hypertensive disorders of pregnancy (HDP). DESIGN: Cross-sectional analysis of health outcomes; physical growth (head circumference, height, and weight) collected at birth and 2 months, corrected for prematurity; and cognitive, language, and motor skills of preterm infants of women with and without HDP. SETTING: Four NICUs in the United States...
November 28, 2018: Journal of Obstetric, Gynecologic, and Neonatal Nursing: JOGNN
https://www.readbyqxmd.com/read/30460694/connection-between-gut-microbiome-and-brain-development-in-preterm-infants
#7
Jing Lu, Erika C Claud
Dysbiosis of the gut microbiome in preterm infants predisposes the neonate to various major morbidities including neonatal necrotizing enterocolitis and sepsis in the neonatal intensive care unit, and adverse neurological outcomes later in life. There are parallel early developmental windows for the gut microbiota and the nervous system during prenatal to postnatal of life. Therefore, preterm infants represent a unique population in which optimization of initial colonization and microbiota development can affect brain development and enhance neurological outcomes...
November 20, 2018: Developmental Psychobiology
https://www.readbyqxmd.com/read/30447814/neuroprotective-care-of-extremely-preterm-infants-in-the-first-72-hours-after-birth
#8
REVIEW
Leslie Altimier, Raylene Phillips
Birth at extremely low gestational ages presents a significant threat to infants' survival, health, development, and future well-being. After birth, a critical period of brain development must continue outside the womb. Neuro-supportive and neuroprotective family centered developmental care for and standardized care practices for extremely preterm infants have been shown to improve outcomes. Neuroprotective interventions must include a focus on the emotional connections of infants and their families. Being in skin-to-skin contact with the mother is the developmentally expected environment for all mammals and is especially important for supporting physiologic stability and neurodevelopment of preterm infants...
December 2018: Critical Care Nursing Clinics of North America
https://www.readbyqxmd.com/read/30375032/randomized-controlled-trial-on-effectiveness-of-mhealth-mobile-smartphone-based-preterm-home-care-program-on-developmental-outcomes-of-preterms-study-protocol
#9
Baby S Nayak, Leslie Edward Lewis, Binu Margaret, Ramesh Bhat Y, Joslin D'Almeida, Tenzin Phagdol
AIM: To describe a randomized controlled trial protocol designed to evaluate the effectiveness of mobile health based Preterm Home Care Program (mHealthPHCP) known as "NeoRaksha" mobile health application in improving parent-infant-interaction, growth and development of preterms. DESIGN: A prospective, randomized controlled clinical trial. The protocol is approved and funded by Department of Biotechnology, Government of India on 2 August 2016. METHODS: A total of 300 preterm-mother dyads admitted to neonatal intensive care unit of a tertiary care hospital will be recruited and randomized to intervention and control group...
October 29, 2018: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/30357263/effect-of-docosahexaenoic-acid-supplementation-vs-placebo-on-developmental-outcomes-of-toddlers-born-preterm-a-randomized-clinical-trial
#10
Sarah A Keim, Kelly M Boone, Mark A Klebanoff, Abigail Norris Turner, Joseph Rausch, Mary Ann Nelin, Lynette K Rogers, Keith Owen Yeates, Leif Nelin, Kelly W Sheppard
Importance: Intake of dietary docosahexaenoic acid (DHA) among toddlers is low. Supplementation may benefit developmental outcomes of toddlers who were born preterm. Objective: To determine whether 6 months of daily DHA supplementation improves developmental outcomes of toddlers who were born preterm. Design, Setting, and Participants: A randomized, fully masked, placebo-controlled trial was conducted from April 26, 2012, to March 24, 2017, at a large US pediatric academic center with 9 neonatal intensive care units...
October 22, 2018: JAMA Pediatrics
https://www.readbyqxmd.com/read/30342897/late-preterm-births-new-insights-from-neonatal-neuroimaging-and-neurobehaviour
#11
REVIEW
Jeanie Ling Yoong Cheong, Deanne Kim Thompson, Joy Elizabeth Olsen, Alicia Jane Spittle
With increasing evidence of neurodevelopmental problems faced by late preterm children, there is a need to explore possible underlying brain structural changes. The use of brain magnetic resonance imaging has provided insights of smaller and less mature brains in infants born late preterm, associated with developmental delay at 2 years. Another useful tool in the newborn period is neurobehavioural assessment, which has also been shown to be suboptimal in late preterm infants compared with tern infants. Suboptimal neurobehaviour is also associated with poorer 2-year neurodevelopment in late preterm infants...
October 14, 2018: Seminars in Fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/30337465/impact-of-prenatal-exercise-on-neonatal-and-childhood-outcomes-a-systematic-review-and-meta-analysis
#12
REVIEW
Margie H Davenport, Victoria L Meah, Stephanie-May Ruchat, Gregory A Davies, Rachel J Skow, Nick Barrowman, Kristi B Adamo, Veronica J Poitras, Casey E Gray, Alejandra Jaramillo Garcia, Frances Sobierajski, Laurel Riske, Marina James, Amariah J Kathol, Megan Nuspl, Andree-Anne Marchand, Taniya S Nagpal, Linda G Slater, Ashley Weeks, Ruben Barakat, Michelle F Mottola
OBJECTIVE: We aimed to identify the relationship between maternal prenatal exercise and birth complications, and neonatal and childhood morphometric, metabolic and developmental outcomes. DESIGN: Systematic review with random-effects meta-analysis and meta-regression. DATA SOURCES: Online databases were searched up to 6 January 2017. STUDY ELIGIBILITY CRITERIA: Studies of all designs were eligible (except case studies and reviews) if published in English, Spanish or French, and contained information on the relevant population (pregnant women without contraindication to exercise), intervention (subjective/objective measures of frequency, intensity, duration, volume or type of exercise, alone ('exercise-only') or in combination with other intervention components (eg, dietary; 'exercise+cointervention')), comparator (no exercise or different frequency, intensity, duration, volume, type or trimester of exercise) and outcomes (preterm birth, gestational age at delivery, birth weight, low birth weight (<2500 g), high birth weight (>4000 g), small for gestational age, large for gestational age, intrauterine growth restriction, neonatal hypoglycaemia, metabolic acidosis (cord blood pH, base excess), hyperbilirubinaemia, Apgar scores, neonatal intensive care unit admittance, shoulder dystocia, brachial plexus injury, neonatal body composition (per cent body fat, body weight, body mass index (BMI), ponderal index), childhood obesity (per cent body fat, body weight, BMI) and developmental milestones (including cognitive, psychosocial, motor skills))...
November 2018: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/30299031/outcomes-of-infants-born-near-term-not-quite-ready-for-the-big-wide-world
#13
Elaine M Boyle, Ranveer S Sanghera
Until recently, there has been a strongly held belief on the part of neonatal and paediatric clinicians that outcomes for infants born close to term are not different from those of babies born at full term. In the last decade, however, this assumption has been challenged by reports suggesting that this is not correct, and highlighting differences in morbidity and mortality both in the short and long term. This has led to development of new terminology to more accurately reflect the impact of immaturity associated with birth at 32-33 weeks (moderately preterm) and 34-36 weeks (late preterm) of gestation...
October 4, 2018: Minerva Pediatrica
https://www.readbyqxmd.com/read/30284883/family-nurture-intervention-for-preterm-infants-facilitates-positive-mother-infant-face-to-face-engagement-at-4-months
#14
Beatrice Beebe, Michael M Myers, Sang Han Lee, Adrianne Lange, Julie Ewing, Nataliya Rubinchik, Howard Andrews, Judy Austin, Amie Hane, Amy E Margolis, Myron Hofer, Robert J Ludwig, Martha G Welch
Although preterm infants are at risk for social deficits, interventions to improve mother-infant interaction in the neonatal intensive care unit (NICU) are not part of standard care (SC). Study participants were a subset from a randomized controlled trial of a new intervention for premature infants, the Family Nurture Intervention (FNI), designed to help mothers and infants establish an emotional connection. At infants' 4 months corrected age, mother-infant face-to-face interaction was filmed and coded on a 1-s time base for mother touch, infant vocal affect, mother gaze, and infant gaze...
November 2018: Developmental Psychology
https://www.readbyqxmd.com/read/30282505/mri-at-term-equivalent-age-for-predicting-long-term-neuro-developmental-outcome-in-preterm-infants-a-cohort-study
#15
Umamaheswari Balakrishnan, Prakash Amboiram, Binu Ninan, Anupama Chandrasekharan, Rajeswaran Rangaswamy, Lalitha Subramanian
INTRODUCTION: Preterm infants are at increased risk of adverse neuro-developmental outcome (NDO). Cranial ultrasound has limited predictability. The aim of the study is to evaluate whether MRI done at term equivalent age (TEA) predicts NDO at 18-22 months of corrected gestational age (CGA). METHOD: This cohort study of preterm infants born at ≤ 32 weeks of gestation and/or birth weight < 1500 grams between April 2011 and August 2012, was conducted in a tertiary care institute in India...
October 3, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/30144852/long-term-functioning-and-participation-across-the-life-course-for-preterm-neonatal-intensive-care-unit-graduates
#16
REVIEW
Frances A Carter, Michael E Msall
To understand the trajectories of risk and resilience in the vulnerable preterm and neonatal brain, clinicians must go beyond survival and critically examine on a population basis the functional outcomes of children, adolescents, and adults across their life course. Evaluations must go well beyond Bayley assessments and counts of neonatal morbidities, such as bronchopulmonary dysplasia, retinopathy of prematurity, sonographic brain injury, sepsis, and necrotizing enterocolitis. Proactively providing support to families and developmental and educational supports to children can optimize academic functioning and participation in adult learning, physical and behavioral health activities, community living, relationships, and employment...
September 2018: Clinics in Perinatology
https://www.readbyqxmd.com/read/30134865/prospective-study-of-early-and-late-outcomes-of-extremely-low-birthweight-in-central-saudi-arabia
#17
Mostafa A Abolfotouh, Saif Al Saif, Waleed A Altwaijri, Mohammed A Al Rowaily
BACKGROUND: Survival of preterm neonates has steadily improved over the past five decades, due to changes in the neonatal intensive care. However, in Saudi Arabia, there are no written guidelines on the definition of the lower limit of viability, and there has been a call for such a limit. The aims of this study were: (1) to determine lower limits of viability and survival in extremely low birthweight (ELBW) infants, and (2) to determine incidence of neurodevelopmental and cognitive abnormalities within 3-6 years after birth...
August 22, 2018: BMC Pediatrics
https://www.readbyqxmd.com/read/30134292/neurodevelopmental-outcomes-and-in-utero-antiretroviral-exposure-in-hiv-exposed-uninfected-children
#18
Micah Piske, Matthew A Budd, Annie Q Qiu, Evelyn J Maan, Laura J Sauvé, John C Forbes, Ariane Alimenti, Patricia Janssen, Hélène C F Côté
OBJECTIVES: To assess and compare neurodevelopmental disorders in HIV-exposed uninfected (HEU) and HIV-unexposed uninfected (HUU) children in British Columbia, Canada. To determine associations between these outcomes and in-utero exposure to antiretroviral drugs. DESIGN: Retrospective controlled cohort study. METHODS: Data were collected on 446 HEU children and 1323 HUU children (matched ∼1 : 3 for age, sex, and geocode) born between 1990 and 2012...
November 13, 2018: AIDS
https://www.readbyqxmd.com/read/30132843/incidence-of-neonatal-seizures-perinatal-risk-factors-for-epilepsy-and-mortality-after-neonatal-seizures-in-the-province-of-parma-italy
#19
Francesco Pisani, Carlotta Facini, Elisa Bianchi, Giorgia Giussani, Benedetta Piccolo, Ettore Beghi
OBJECTIVE: Information about the incidence of neonatal seizures (NS) is scarce. Previous studies relied primarily on a clinical diagnosis of seizures. This population-based, retrospective study evaluated the incidence of electroencephalography (EEG)-confirmed seizures in neonates born in the province of Parma and the perinatal risk factors for mortality and epilepsy. METHODS: All neonates with suspected seizures or with medical conditions at high risk for seizures from the study area were recorded in the neonatal intensive care unit (NICU) of the Parma University Hospital...
September 2018: Epilepsia
https://www.readbyqxmd.com/read/30131711/the-role-of-abnormal-placentation-in-congenital-heart-disease-cause-correlate-or-consequence
#20
Jennifer A Courtney, James F Cnota, Helen N Jones
Congenital heart disease (CHD) is the most common birth defect, affecting ~1% of all live births (van der Linde et al., 2011). Despite improvements in clinical care, it is the leading cause of infant mortality related to birth defects (Yang et al., 2006) and burdens survivors with significant morbidity (Gilboa et al., 2016). Furthermore, CHD accounts for the largest proportion (26.7%) of birth defect-associated hospitalization costs-up to $6.1 billion in 2013 (Arth et al., 2017). Yet after decades of research with a primary focus on genetic etiology, the underlying cause of these defects remains unknown in the majority of cases (Zaidi and Brueckner, 2017)...
2018: Frontiers in Physiology
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