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https://www.readbyqxmd.com/read/30337465/impact-of-prenatal-exercise-on-neonatal-and-childhood-outcomes-a-systematic-review-and-meta-analysis
#1
REVIEW
Margie H Davenport, Victoria L Meah, Stephanie-May Ruchat, Gregory A Davies, Rachel J Skow, Nick Barrowman, Kristi B Adamo, Veronica J Poitras, Casey E Gray, Alejandra Jaramillo Garcia, Frances Sobierajski, Laurel Riske, Marina James, Amariah J Kathol, Megan Nuspl, Andree-Anne Marchand, Taniya S Nagpal, Linda G Slater, Ashley Weeks, Ruben Barakat, Michelle F Mottola
OBJECTIVE: We aimed to identify the relationship between maternal prenatal exercise and birth complications, and neonatal and childhood morphometric, metabolic and developmental outcomes. DESIGN: Systematic review with random-effects meta-analysis and meta-regression. DATA SOURCES: Online databases were searched up to 6 January 2017. STUDY ELIGIBILITY CRITERIA: Studies of all designs were eligible (except case studies and reviews) if published in English, Spanish or French, and contained information on the relevant population (pregnant women without contraindication to exercise), intervention (subjective/objective measures of frequency, intensity, duration, volume or type of exercise, alone ('exercise-only') or in combination with other intervention components (eg, dietary; 'exercise+cointervention')), comparator (no exercise or different frequency, intensity, duration, volume, type or trimester of exercise) and outcomes (preterm birth, gestational age at delivery, birth weight, low birth weight (<2500 g), high birth weight (>4000 g), small for gestational age, large for gestational age, intrauterine growth restriction, neonatal hypoglycaemia, metabolic acidosis (cord blood pH, base excess), hyperbilirubinaemia, Apgar scores, neonatal intensive care unit admittance, shoulder dystocia, brachial plexus injury, neonatal body composition (per cent body fat, body weight, body mass index (BMI), ponderal index), childhood obesity (per cent body fat, body weight, BMI) and developmental milestones (including cognitive, psychosocial, motor skills))...
November 2018: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/30299031/outcomes-of-infants-born-near-term-not-quite-ready-for-the-big-wide-world
#2
Elaine M Boyle, Ranveer S Sanghera
Until recently, there has been a strongly held belief on the part of neonatal and paediatric clinicians that outcomes for infants born close to term are not different from those of babies born at full term. In the last decade, however, this assumption has been challenged by reports suggesting that this is not correct, and highlighting differences in morbidity and mortality both in the short and long term. This has led to development of new terminology to more accurately reflect the impact of immaturity associated with birth at 32-33 weeks (moderately preterm) and 34-36 weeks (late preterm) of gestation...
October 4, 2018: Minerva Pediatrica
https://www.readbyqxmd.com/read/30284883/family-nurture-intervention-for-preterm-infants-facilitates-positive-mother-infant-face-to-face-engagement-at-4-months
#3
Beatrice Beebe, Michael M Myers, Sang Han Lee, Adrianne Lange, Julie Ewing, Nataliya Rubinchik, Howard Andrews, Judy Austin, Amie Hane, Amy E Margolis, Myron Hofer, Robert J Ludwig, Martha G Welch
Although preterm infants are at risk for social deficits, interventions to improve mother-infant interaction in the neonatal intensive care unit (NICU) are not part of standard care (SC). Study participants were a subset from a randomized controlled trial of a new intervention for premature infants, the Family Nurture Intervention (FNI), designed to help mothers and infants establish an emotional connection. At infants' 4 months corrected age, mother-infant face-to-face interaction was filmed and coded on a 1-s time base for mother touch, infant vocal affect, mother gaze, and infant gaze...
October 4, 2018: Developmental Psychology
https://www.readbyqxmd.com/read/30282505/mri-at-term-equivalent-age-for-predicting-long-term-neuro-developmental-outcome-in-preterm-infants-a-cohort-study
#4
Umamaheswari Balakrishnan, Prakash Amboiram, Binu Ninan, Anupama Chandrasekharan, Rajeswaran Rangaswamy, Lalitha Subramanian
INTRODUCTION: Preterm infants are at increased risk of adverse neuro-developmental outcome (NDO). Cranial ultrasound has limited predictability. The aim of the study is to evaluate whether MRI done at term equivalent age (TEA) predicts NDO at 18-22 months of corrected gestational age (CGA). METHOD: This cohort study of preterm infants born at ≤ 32 weeks of gestation and/or birth weight < 1500 grams between April 2011 and August 2012, was conducted in a tertiary care institute in India...
October 3, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/30144852/long-term-functioning-and-participation-across-the-life-course-for-preterm-neonatal-intensive-care-unit-graduates
#5
REVIEW
Frances A Carter, Michael E Msall
To understand the trajectories of risk and resilience in the vulnerable preterm and neonatal brain, clinicians must go beyond survival and critically examine on a population basis the functional outcomes of children, adolescents, and adults across their life course. Evaluations must go well beyond Bayley assessments and counts of neonatal morbidities, such as bronchopulmonary dysplasia, retinopathy of prematurity, sonographic brain injury, sepsis, and necrotizing enterocolitis. Proactively providing support to families and developmental and educational supports to children can optimize academic functioning and participation in adult learning, physical and behavioral health activities, community living, relationships, and employment...
September 2018: Clinics in Perinatology
https://www.readbyqxmd.com/read/30134865/prospective-study-of-early-and-late-outcomes-of-extremely-low-birthweight-in-central-saudi-arabia
#6
Mostafa A Abolfotouh, Saif Al Saif, Waleed A Altwaijri, Mohammed A Al Rowaily
BACKGROUND: Survival of preterm neonates has steadily improved over the past five decades, due to changes in the neonatal intensive care. However, in Saudi Arabia, there are no written guidelines on the definition of the lower limit of viability, and there has been a call for such a limit. The aims of this study were: (1) to determine lower limits of viability and survival in extremely low birthweight (ELBW) infants, and (2) to determine incidence of neurodevelopmental and cognitive abnormalities within 3-6 years after birth...
August 22, 2018: BMC Pediatrics
https://www.readbyqxmd.com/read/30134292/neurodevelopmental-outcomes-and-in-utero-antiretroviral-exposure-in-hiv-exposed-uninfected-children
#7
Micah Piske, Matthew A Budd, Annie Q Qiu, Evelyn J Maan, Laura J Sauvé, John C Forbes, Ariane Alimenti, Patricia Janssen, Hélène C F Côté
OBJECTIVES: To assess and compare neurodevelopmental disorders (NDs) in HIV-exposed uninfected (HEU) and HIV-unexposed uninfected (HUU) children in British Columbia (BC), Canada. To determine associations between these outcomes and in utero exposure to antiretroviral (ARV) drugs. DESIGN: Retrospective controlled cohort study. METHODS: Data were collected on 446 HEU children and 1323 HUU children (matched ∼1:3 for age, sex, and geocode) born between 1990 and 2012...
August 20, 2018: AIDS
https://www.readbyqxmd.com/read/30132843/incidence-of-neonatal-seizures-perinatal-risk-factors-for-epilepsy-and-mortality-after-neonatal-seizures-in-the-province-of-parma-italy
#8
Francesco Pisani, Carlotta Facini, Elisa Bianchi, Giorgia Giussani, Benedetta Piccolo, Ettore Beghi
OBJECTIVE: Information about the incidence of neonatal seizures (NS) is scarce. Previous studies relied primarily on a clinical diagnosis of seizures. This population-based, retrospective study evaluated the incidence of electroencephalography (EEG)-confirmed seizures in neonates born in the province of Parma and the perinatal risk factors for mortality and epilepsy. METHODS: All neonates with suspected seizures or with medical conditions at high risk for seizures from the study area were recorded in the neonatal intensive care unit (NICU) of the Parma University Hospital...
September 2018: Epilepsia
https://www.readbyqxmd.com/read/30131711/the-role-of-abnormal-placentation-in-congenital-heart-disease-cause-correlate-or-consequence
#9
Jennifer A Courtney, James F Cnota, Helen N Jones
Congenital heart disease (CHD) is the most common birth defect, affecting ~1% of all live births (van der Linde et al., 2011). Despite improvements in clinical care, it is the leading cause of infant mortality related to birth defects (Yang et al., 2006) and burdens survivors with significant morbidity (Gilboa et al., 2016). Furthermore, CHD accounts for the largest proportion (26.7%) of birth defect-associated hospitalization costs-up to $6.1 billion in 2013 (Arth et al., 2017). Yet after decades of research with a primary focus on genetic etiology, the underlying cause of these defects remains unknown in the majority of cases (Zaidi and Brueckner, 2017)...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/30122083/developmental-regulation-of-the-gut-liver-fgf19-cyp7a1-axis-in-neonates
#10
Naureen Memon, Ian J Griffin, Chris W Lee, Aimee Herdt, Barry I Weinberger, Thomas Hegyi, Mary O Carayannopoulos, Lauren M Aleksunes, Grace L Guo
INTRODUCTION: Fibroblast growth factor 19 (FGF19) is a gut-derived hormone that regulates the expression of CYP7A1, the rate-limiting enzyme in bile acid (BA) synthesis pathway. Dysregulation of the FGF19-CYP7A1 (gut-liver) axis is associated with cholestatic liver disease. Infants, especially preterm infants and those with intestinal failure are at high risk for developing cholestatic liver disease. The activity of the gut-liver axis has not been characterized in this population. Our objective was to assess relationships between circulating FGF19 concentrations and CYP7A1 activity in neonates...
August 19, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/30101715/preterm-birth-long-term-cardiovascular-and-renal-consequences
#11
Hassib Chehade, Umberto Simeoni, Jean-Pierre Guignard, Farid Boubred
Cardiovascular and chronic kidney diseases are part of non-communicable chronic diseases, the leading causes of premature death worldwide. They are recognized as having early origins through altered developmental programming, due to adverse environmental conditions during development. Preterm birth is increasingly recognized as such an adverse factor. Rates of preterm birth have increased the last decades, however, with the improvement in perinatal and neonatal care, a growing cohort have survived to the neonatal period and are now entering adulthood...
August 13, 2018: Current Pediatric Reviews
https://www.readbyqxmd.com/read/30098111/nonpharmacological-interventions-for-sleep-promotion-on-preterm-infants-in-neonatal-intensive-care-unit-a-systematic-review
#12
REVIEW
Jin-Hua Liao, Rong-Fang Hu, Li-Jing Su, Shuo Wang, Qin Xu, Xiao-Fang Qian, Hong-Gu He
BACKGROUND: Nonpharmacological interventions are often used to promote sleep among preterm infants in the neonatal intensive care unit (NICU). However, there is a lack of synthesis in the evidence of their effectiveness. AIM: To synthesize the evidence on the effectiveness of nonpharmacological interventions on NICU preterm infants' sleep during hospital stay. METHODS: Seven databases were searched, including MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, Wan-fang database, China National Knowledge Infrastructure, China Biological Medicine Database, and VIP Journal Integration Platform from their inceptions to August 2017...
October 2018: Worldviews on Evidence-based Nursing
https://www.readbyqxmd.com/read/30092772/early-intervention-program-for-very-low-birth-weight-preterm-infants-and-their-parents-a-study-protocol
#13
Rita C Silveira, Eliane Wagner Mendes, Rubia Nascimento Fuentefria, Nadia Cristina Valentini, Renato S Procianoy
BACKGROUND: Preterm infants are high risk for delayed neurodevelopment. The main goal is to develop a program of early intervention for very preterm infants that allows families to apply it continuously at home, and quantify the results of early parental stimulation on improvement of cognition and motor skills. METHODS: Randomized clinical Trial including inborn preterm infants with gestational age less than 32 weeks or birth weight less than 1500 g at 48 h after birth...
August 9, 2018: BMC Pediatrics
https://www.readbyqxmd.com/read/30091495/a-modified-developmental-care-bundle-reduces-pain-and-stress-in-preterm-infants-undergoing-examinations-for-retinopathy-of-prematurity-a-randomised-controlled-trial
#14
Ling-Ju Chuang, Shih-Hao Wang, Mi-Chia Ma, Chia-Ni Lin, Chih-Ling Chen, Mei-Chih Huang
AIMS AND OBJECTIVES: To determine the comparative efficacy of developmental care versus standard care for reducing pain and stress in preterm infants during examinations for retinopathy of prematurity (ROP). BACKGROUND: ROP examinations are routinely performed in neonatal intensive care units to detect these lesions. Pain scores recorded during and after eye examinations have revealed physiological and behavioural manifestations of pain and stress. DESIGN: A randomised crossover trial was conducted...
August 9, 2018: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/30089217/neonatal-stress-and-resilience-lasting-effects-of-antenatal-corticosteroids
#15
Alan Hall Jobe
Antenatal corticosteroids (ACS) are standard of care for women at risk of preterm delivery between 24 -34 weeks gestation. Their use decreases preterm morbidities and mortality. However, ACS treatments mimic a stress response by increasing fetal steroid levels at early gestational ages when the fetus is normally protected from high glucocorticoid levels. Within the context of concept of the developmental origins of adult health and disease, ACS are effective stressors in fetal animal models that alter developmental programs and outcome in adult animals...
August 8, 2018: Canadian Journal of Physiology and Pharmacology
https://www.readbyqxmd.com/read/30089091/less-is-more-modern-neonatology
#16
REVIEW
Amir Kugelman, Liron Borenstein-Levin, Huda Jubran, Gil Dinur, Shlomit Ben-David, Elena Segal, Julie Haddad, Fanny Timstut, Iris Stein, Imad R Makhoul, Ori Hochwald
Iatrogenesis is more common in neonatal intensive care units (NICUs) because the infants are vulnerable and exposed to prolonged intensive care. Sixty percent of extremely low-birth-weight infants are exposed to iatrogenesis. The risk factors for iatrogenesis in NICUs include prematurity, mechanical or non-invasive ventilation, central lines, and prolonged length of stay. This led to the notion that "less is more." In the delivery room delayed cord clamping is recommended for term and preterm infants, and suction for the airways in newborns with meconium-stained fluid is not performed anymore...
July 30, 2018: Rambam Maimonides Medical Journal
https://www.readbyqxmd.com/read/30026767/effect-of-multi-sensory-stimulation-on-neuromuscular-development-of-premature-infants-a-randomized-clinical-trial
#17
Hossein Zeraati, Fatemeh Nasimi, Akram Rezaeian, Javad Shahinfar, Maryam Ghorban Zade
Objectives: Preterm birth is considered as a risk factor for developmental disabilities, which can lead to long-term effects on the nervous system of children. The aim of this study was to determine the effect of multi-sensory stimulation on neurodevelopment of premature infants. Materials and Methods: In this two-group double-blind clinical trial in Jahrom Hospital, Jahrom, Iran from Jun to Aug 2016, 80 preterm infants were randomly divided. The intervention group received multisensory stimulation for 12 min per session, 5 sessions per wk along with routine NICU care and the control group received ward's routine care...
2018: Iranian Journal of Child Neurology
https://www.readbyqxmd.com/read/30021468/effect-of-maternal-psychopathology-on-neurodevelopmental-outcome-and-quality-of-the-dyadic-relationship-in-preterm-infants-an-explorative-study
#18
C Pisoni, S Spairani, F Fauci, G Ariaudo, C Tzialla, C Tinelli, P Politi, U Balottin, M Stronati, S Orcesi
BACKGROUND: The literature shows that parents of preterm infants are at risk of psychological distress and that this may impact on the quality of the parent-child relationship and on the child's development. AIM: This longitudinal study was conducted to examine in preterm infants relationships between maternal psychological variables, parental protective factors, perinatal infant variables, and neurodevelopmental outcome. Furthermore, we explored the impact of these variables on the quality of the mother-infant relationship (dyadic synchrony)...
July 18, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29989087/breastfeeding-self-efficacy-and-breastmilk-feeding-for-moderate-and-late-preterm-infants-in-the-family-integrated-care-trial-a-mixed-methods-protocol
#19
Meredith Brockway, Karen M Benzies, Eloise Carr, Khalid Aziz
Background: Breastmilk is the ideal nutrition for preterm infants. Yet, breastmilk feeding rates among preterm infants are substantially lower than those of full-term infants. Barriers incurred through hospital care practices as well as the physical environment of the neonatal intensive care unit (NICU) can result in physical and emotional separation of infants from their parents, posing a substantial risk to establishing and maintaining breastfeeding. Additionally, current practitioner-focused care provision in the NICU can result in decreased breastfeeding self-efficacy (BSE), which is predictive of breastfeeding rates in mothers of preterm infants at 6 weeks postpartum...
2018: International Breastfeeding Journal
https://www.readbyqxmd.com/read/29972635/improved-growth-and-developmental-activity-post-tracheostomy-in-preterm-infants-with-severe-bpd
#20
Jun Luo, Suzanne Shepard, Kathleen Nilan, Audrey Wood, Heather M Monk, Erik A Jensen, Ann T Harrington, Kathryn Maschhoff, Haresh Kirpalani, Zhichun Feng, Huayan Zhang
OBJECTIVES: To examine growth, sedation needs, and participation in developmental activities before and after tracheostomy among infants with severe bronchopulmonary dysplasia. METHODS: Retrospective analysis of infants born at <32 weeks' gestation or birth weights <1500 g with severe BPD who underwent tracheostomy placement between January 1, 2010 and December 31, 2016 in a quaternary referral newborn and infant intensive care unit. Changes in growth parameters and frequency/type of participation in physical therapy sessions performed during the 4-weeks before tracheostomy and 4-weeks after the first tracheostomy tube change were compared...
September 2018: Pediatric Pulmonology
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