Zarema Barakhoeva, Lyudmila Vovk, Yulia Fetisova, Nina Marilova, Maria Ovchinnikova, Marina Tischenko, Yulia Scherbatyuk, Alexandra Kolotovkina, Anna Miskun, Galina Kasyanova, Tatyana Teterina, Irina Zorina, Nadezhda Belousova, Ekaterina Morozova, Sergey Yakovenko, Valentina Apryshko, Lali Sichinava, Raisa Shalinа, Mikhail Polzikov
OBJECTIVE: The aim of the present study was to investigate the therapeutic equivalence between the follitropin alpha biosimilar and the reference medication in women undergoing assisted reproductive technologies (ART). STUDY DESIGN: This multicenter, randomized (1:1), embryologist-blinded, parallel-group, comparative phase III study involved 110 women aged 20-35 years old with tubal and/or male factors of infertility. All of the subjects underwent controlled ovarian hyperstimulation (COH) using a gonadotropin-releasing hormone antagonist (GnRH-ant) protocol...
October 2019: European Journal of Obstetrics, Gynecology, and Reproductive Biology