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Sanna Toppila-Salmi, Heikki Rihkanen, Martti Arffman, Kristiina Manderbacka, Ilmo Keskimaki, Maija L Hytönen
OBJECTIVES: Endoscopic sinus surgery (ESS) is a common operation typically performed due to chronic rhinosinusitis (CRS). There are limited data on the nationwide ESS rate and factors contributing to its regional variation. The aim was to evaluate factors causing variation of ESS rate. DESIGN: Cross-sectional nationwide observational study. SETTING: A ll patients undergoing ESS in Finland 2013-2015. POPULATION: Nationwide Finnish population aged 15 years or over...
October 18, 2018: BMJ Open
Jean Stafford, Robert Howard, Christina Dalman, James B Kirkbride
Background: There are limited data on the epidemiology of very late-onset schizophrenia-like psychosis (VLOSLP) and how this relates to potential risk factors including migration, sensory impairment, traumatic life events, and social isolation. Methods: We followed up a cohort of 3 007 378 people living in Sweden, born 1920-1949, from their 60th birthday (earliest: January 15, 1980) until December 30 2011, emigration, death, or first recorded diagnosis of nonaffective psychosis...
October 19, 2018: Schizophrenia Bulletin
Kjell Grankvist, Gudmundur Sigthorsson, Gunn B Kristensen, Jonna Pelanti, Mads Nybo
The preanalytical phase contains a vast number of practices whose variation may influence the results of laboratory testing and should, therefore, be standardized. The Working Group on Preanalytical Phase of the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM WG-PA) has suggested a standardization of venous blood specimen collection (VBSC) requirements for fasting samples including 12 h fasting time and water ad lib in the morning prior to specimen collection. The Nordic Scientific Preanalytical Working Group investigated the fasting definitions used in the Nordic countries...
October 19, 2018: Scandinavian Journal of Clinical and Laboratory Investigation
Sofia Ny, Roman Kozlov, Uga Dumpis, Petra Edquist, Kirsi Gröndahl-Yli-Hannuksela, Anna-Maria Kling, Danuta O Lis, Christoph Lübbert, Monika Pomorska-Wesołowska, Ivan Palagin, Aija Vilde, Jaana Vuopio, Jan Walter, Karin Tegmark Wisell
We investigated the faecal carriage prevalence of extended-spectrum β-lactamase production in Escherichia coli (EP-EC) and/or Klebsiella pneumoniae (EP-KP) and risk factors associated with carriage among adult study subjects in Finland, Germany, Latvia, Poland, Russia and Sweden (partner countries). The aim was to get indicative data on the prevalence of ESBL-carriage in specific populations in the region. Faecal samples were collected from four study populations and screened on ChromID-ESBL and ChromID-OXA-48 plates...
October 18, 2018: European Journal of Clinical Microbiology & Infectious Diseases
Eira Viikari-Juntura, Taina Leinonen, Lauri J Virta, Ismo Hiljanen, Kirsti Husgafvel-Pursiainen, Ilona Autti-Rämö, Pekka Rissanen, Alex Burdorf, Svetlana Solovieva
Objectives We analyzed social security costs based on an earlier quasi-experiment that compared work participation between partial sickness beneficiaries and a matched group of full sickness beneficiaries. Methods Utilizing a population-based 70% representative sample, 1878 persons with part-time sick leave (intervention group) due to musculoskeletal diseases or mental disorders at an early stage of work disability and their propensity-score-matched controls with full-time sick leave were followed for two years...
October 19, 2018: Scandinavian Journal of Work, Environment & Health
Elina Paakala, Daniel Martín-Collado, Asko Mäki-Tanila, Jarmo Juga
Changing production circumstances, a wide range of traits and the international bull market enable dairy farmers to make increasingly specific choices concerning artificial insemination (AI) bulls. Finland is part of the joint Nordic dairy cattle breeding programme where in addition to yield, high emphasis is given to health, fertility, conformation and longevity. The aims of our study were (a) to investigate whether Finnish dairy farmers differ in their selection preferences for AI bull traits and can be clustered into herd groups, (b) to determine whether AI bull selection in different herd groups is in line with the Nordic Total Merit index (NTM) and (c) to analyse how the herd groups are related to herd characteristics...
October 17, 2018: Journal of Animal Breeding and Genetics, Zeitschrift Für Tierzüchtung und Züchtungsbiologie
Karri Seppä, Håvard Rue, Timo Hakulinen, Esa Läärä, Mikko J Sillanpää, Janne Pitkäniemi
Models of excess mortality with random effects were used to estimate regional variation in relative or net survival of cancer patients. Statistical inference for these models based on the Markov chain Monte Carlo (MCMC) methods is computationally intensive and, therefore, not feasible for routine analyses of cancer register data. This study assessed the performance of the integrated nested Laplace approximation (INLA) in monitoring regional variation in cancer survival. Poisson regression model of excess mortality including both spatially correlated and unstructured random effects was fitted to the data of patients diagnosed with ovarian and breast cancer in Finland during 1955-2014 with follow up from 1960 through 2014 by using the period approach with five-year calendar time windows...
October 17, 2018: Statistics in Medicine
Sophia I Passy, Chad A Larson, Aurélien Jamoneau, William Budnick, Jani Heino, Thibault Leboucher, Juliette Tison-Rosebery, Janne Soininen
In this intercontinental study of stream diatoms, we asked three important but still unresolved ecological questions: (1) What factors drive the biogeography of species richness and species abundance distribution (SAD)? (2) Are climate-related hypotheses, which have dominated the research on the latitudinal and altitudinal diversity gradients, adequate in explaining spatial biotic variability? and (3) Is the SAD response to the environment independent of richness? We tested a number of climatic theories and hypotheses (i...
November 2018: American Naturalist
Caitlin N Dodd, Maria de Ridder, Wan-Ting Huang, Daniel Weibel, Maria Giner-Soriano, Silvia Perez-Vilar, Javier Diez-Domingo, Lawrence W Svenson, Salahddin M Mahmud, Bruce Carleton, Monika Naus, Jeffrey C Kwong, Brian J Murray, Lisen Arnheim-Dahlstrom, Lars Pedersen, Rosa Morros, Francisco Javier Puertas, Steven Black, Miriam Sturkenboom
BACKGROUND & OBJECTIVES: Vaccine safety signals require investigation, which may be done rapidly at the population level using ecological studies, before embarking on hypothesis-testing studies. Incidence rates were used to assess a signal of narcolepsy following AS03-adjuvanted monovalent pandemic H1N1 (pH1N1) influenza vaccination among children and adolescents in Sweden and Finland in 2010. We explored the utility of ecological data to assess incidence of narcolepsy following exposure to pandemic H1N1 virus or vaccination in 10 sites that used different vaccines, adjuvants, and had varying vaccine coverage...
2018: PloS One
Isabell K Rumrich, Kirsi Vähäkangas, Matti Viluksela, Mika Gissler, Heljä-Marja Surcel, Antti Korhonen, Hanna De Ruyter, Otto Hänninen
AIMS: In Finland, smoking rates in the general population are decreasing due to increased awareness of the adverse effects and tightened tobacco legislation. However, previous studies have shown that smoking in pregnant Finnish women remained as high as in the general Finnish female population at around 15% in 2010. Our aim was to describe temporal and spatial trends in smoking behaviour, and determinants of changes in smoking behaviour between first and second pregnancy. METHODS: Self-reported smoking from the Finnish Medical Birth Register covered the years 1991-2015 ( N=1,435,009)...
October 17, 2018: Scandinavian Journal of Public Health
Satu Strausz, Aki S Havulinna, Tiinamaija Tuomi, Adel Bachour, Leif Groop, Antti Mäkitie, Seppo Koskinen, Veikko Salomaa, Aarno Palotie, Samuli Ripatti, Tuula Palotie
OBJECTIVE: To evaluate if obstructive sleep apnoea (OSA) modifies the risk of coronary heart disease, type 2 diabetes (T2D) and diabetic complications in a gender-specific fashion. DESIGN AND SETTING: A longitudinal population-based study with up to 25-year follow-up data on 36 963 individuals (>500 000 person years) from three population-based cohorts: the FINRISK study, the Health 2000 Cohort Study and the Botnia Study. MAIN OUTCOME MEASURES: Incident coronary heart disease, diabetic kidney disease, T2D and all-cause mortality from the Finnish National Hospital Discharge Register and the Finnish National Causes-of-Death Register...
October 15, 2018: BMJ Open
M Lövgren, N Mogensen, A Harila-Saari, P M Lähteenmäki, U Kreicbergs
Evidence favours sibling support as a standard of care in paediatric oncology (1). Guidelines published in 1999 by the International Society of Paediatric Oncology (2) recommended involving siblings in the ill child's care and supporting siblings during and after the illness. Studies have shown that this is something that siblings want and need (3) and lack of support has increased the risk of long-term psychological distress (4). Sibling support varies between countries. This article is protected by copyright...
October 16, 2018: Acta Paediatrica
S Juujärvi, H Kallankari, P Pätsi, M Leskinen, T Saarela, M Hallman, O Aikio
AIM: We examined the long-term outcomes and safety of early intravenous paracetamol for ductus arteriosus closure at a corrected age of two years. METHODS: This was a follow-up of the 2013-2014 randomised, double-blind Preterm Infant's Paracetamol Study at Oulu University Hospital, Finland, which recruited 48 very preterm infants within 24 hours of birth. They received intravenous paracetamol or a placebo for four days. In 2015-2017 we followed up 44 infants (92%) at two years of corrected age...
October 16, 2018: Acta Paediatrica
Idil Hussein, Jussi Sane, Hanna Soini, Tuula Vasankari, Outi Lyytikäinen
Background: In Finland, the epidemiology of tuberculosis is changing: incidence declined from 13/100 000 in 1995 to 4 in 2016 and the proportion of foreign-borns among all TB cases increased from 5% to 50%. The most common country of origin among foreign-born TB patients was Somalia. Knowledge, attitudes and practices (KAP) studies are used to collect information for planning and tailoring health care services. KAP studies in Finland have been used for other diseases but not to study Somalis in regards to TB...
October 15, 2018: European Journal of Public Health
Kaja Põlluste, Elise Kosunen, Tuomas Koskela, Kari J Mattila, Willemijn L A Schäfer, Wienke G W Boerma, Margus Lember
INTRODUCTION: Since the early 1990s, the Estonian and Finnish health systems have undergone various changes which are expected to have impacted the type and range of services provided by general practitioners (GPs). OBJECTIVE: To compare GP services between Estonia and Finland in 1993 and 2012 and draw a parallel with transformations occurred in the health systems of both countries during these two decades. METHODS: Data were collected through surveys among 129 and 288 GPs from Estonia and Finland in 2012 and 139 Estonian and 239 Finnish GPs in 1993...
October 9, 2018: Health Policy
Mikko Pänkäläinen, Mikael Fogelholm, Raisa Valve, Olli Kampman, Markku Kauppi, Erja Lappalainen, Jukka Hintikka
BACKGROUND: Dietary habits have a great influence on physiological health. Even though this fact is generally recognized, people do not eat as healthily as they know they should. The factors that support a healthy diet, on the other hand, are not well known. It is supposed that there is a link between personal traits and dietary habits. Personal traits may also partially explain why some people manage to make healthy dietary changes while some fail to do so or are not able to try to make changes even when they desire to do so...
October 15, 2018: Nutrition Journal
Kishor Hadkhale, Jan Ivar Martinsen, Elisabete Weiderpass, Kristina Kjærheim, Pär Sparén, Laufey Tryggvadóttir, Elsebeth Lynge, Eero Pukkala
BACKGROUND: Occupational exposure has been identified as the most important risk factor for bladder cancer second to smoking. The objective of this study was to estimate the occupational variation in risk of bladder cancer that is not attributable to smoking. MATERIAL AND METHODS: In the Nordic Occupational Cancer study (NOCCA), 111,458 cases of bladder cancer and 208,297 cases of lung cancer cases were observed among men in Denmark, Finland, Iceland, Norway and Sweden during 1961-2005...
October 15, 2018: Acta Oncologica
Anna-Maija Tolppanen, Miia Tiihonen, Heidi Taipale, Marjaana Koponen, Antti Tanskanen, Piia Lavikainen, Jari Tiihonen, Sirpa Hartikainen
BACKGROUND: It is unknown whether cognitive status or diagnosed cognitive decline affects estrogen use. OBJECTIVES: We assessed how common systemic estrogen use was among community-dwellers with Alzheimer's disease (AD) and a matched comparison cohort without AD. METHODS: This study included an exposure-matched cohort of all Finnish community-dwelling women who received a clinically verified diagnosis of AD in 2005-2011 (N = 46,116; index cases) and an equally sized matched comparison cohort without AD...
October 13, 2018: Drugs & Aging
M Mäkinen, M Castrén, K Huttunen, S Sundell, J Kaartinen, M Ben-Meir, M Renholm
OBJECTIVE: The objective of the study is to assess how well the emergency department (ED) personnel succeed in instructing the patient at discharge. METHODS: In November and December 2016 at Peijas Hospital ED, Finland, a structured questionnaire was conducted during a phone interview on patients the day after discharge. RESULTS: A total of 132 patients interviewed. Ninety percent had received discharge instructions from the ED staff, most of them (75%) about medication...
October 10, 2018: International Emergency Nursing
M Slagboom, A Wallenbeck, L Hjortø, A C Sørensen, L Rydhmer, J R Thomasen, M Kargo
In Denmark, Finland, and Sweden, the Nordic Total Merit index is used as the breeding selection tool for both organic and conventional dairy farmers based on common economic models for conventional dairy farming. Organic farming is based on the principles of organic agriculture (POA) defined by the International Federation of Organic Agriculture Movements. These principles are not set up with an economic point of view, and therefore it may be questionable to use a breeding goal (BG) for organic dairy production based on economic models...
October 10, 2018: Journal of Dairy Science
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