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https://www.readbyqxmd.com/read/30341872/amlodipine-in-the-era-of-new-generation-calcium-channel-blockers
#1
Mangesh Tiwaskar, Amit Langote, Resham Kashyap, Archana Toppo
Amlodipine is a classical drug with varied properties extending from control of blood pressure to as an antianginal and anti atherosclerotic agent. Amlodipine is a longer acting dihydropyridine calcium channel blocker, effective for 24 hours BP control and cause no BP variability. It is a powerful, well-tolerated, and safe antihypertensive agents that is widely used either alone or as a key component of combination therapy for hypertension. Its effective BP reduction has shown proven benefits in cardiovascular event reduction that is supported with strong evidences from large randomised controlled trials...
March 2018: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/30341579/prognostic-value-of-estimated-plasma-volume-in-acute-heart-failure-in-three-cohort-studies
#2
Masatake Kobayashi, Patrick Rossignol, João Pedro Ferreira, Irene Aragão, Yuki Paku, Yoichi Iwasaki, Masataka Watanabe, Marat Fudim, Kevin Duarte, Faiez Zannad, Nicolas Girerd
AIMS: Estimated plasma volume status (ePVS) predicts prognosis in patients with heart failure (HF). It remains unclear whether admission, discharge or change ePVS best predicts post-discharge outcome in patients with acute decompensated heart failure (ADHF). METHODS: We retrospectively analyzed three cohort studies: 383 patients admitted at the Tokyo Medical University hospital, 165 patients admitted at the Centro Hospitalar do Porto and 164 patients admitted at the Université de Lorraine (ICALOR study)...
October 19, 2018: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/30341059/hybridization-between-char-species-salvelinus-alpinus-and-salvelinus-fontinalis-a-fast-track-for-novel-allometric-trajectories
#3
Bernard-Antonin Dupont Cyr, France Dufresne, Felix Christen, Véronique Desrosiers, Émilie Proulx, Nathalie R Le François, Grant W Vandenberg, Pierre U Blier
Hybridization between closely related species can generate genetic and phenotypic variation, providing valuable biological material to assess the physiological impact of the structural or functional variability of different organs. In the present study, we examined growth rates of various organs and whole body in brook char, Arctic char and their reciprocal hybrids over a period of 281 days. Parental species achieved significantly higher body mass than their hybrids. Hybridization significantly reduced the relative size of the heart, liver and spleen...
October 19, 2018: Biology Open
https://www.readbyqxmd.com/read/30340936/predictors-of-recurrent-hospitalizations-and-the-importance-of-these-hospitalizations-for-subsequent-mortality-after-incident-transient-ischemic-attack
#4
Mohammed Yousufuddin, Nathan Young, Jessica Shultz, Taylor Doyle, Karen M Fuerstenberg, Kelsey Jensen, Kogulavadanan Arumaithurai, Mohammad H Murad
BACKGROUND: We examined predictors of recurrent hospitalizations and the importance of these hospitalizations for subsequent mortality after incident transient ischemic attacks (TIA) that have not yet been investigated. METHODS: Adults hospitalized for TIA from 2000 through 2017 were examined for recurrent hospitalizations, days, and percentage of time spent hospitalized and long-term mortality. RESULTS: Of 266 patients hospitalized for TIA, 122 died, 212 had 826 anycondition hospitalization (59 from TIA-related conditions) corresponding to 3384 inpatient days during 1693 person-years of follow-up...
October 16, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/30340503/aerobic-and-resistance-exercise-improves-physical-fitness-bone-health-and-quality-of-life-in-overweight-and-obese-breast-cancer-survivors-a-randomized-controlled-trial
#5
Christina M Dieli-Conwright, Kerry S Courneya, Wendy Demark-Wahnefried, Nathalie Sami, Kyuwan Lee, Frank C Sweeney, Christina Stewart, Thomas A Buchanan, Darcy Spicer, Debu Tripathy, Leslie Bernstein, Joanne E Mortimer
BACKGROUND: Exercise is an effective strategy to improve quality of life and physical fitness in breast cancer survivors; however, few studies have focused on the early survivorship period, minorities, physically inactive and obese women, or tested a combined exercise program and measured bone health. Here, we report the effects of a 16-week aerobic and resistance exercise intervention on patient-reported outcomes, physical fitness, and bone health in ethnically diverse, physically inactive, overweight or obese breast cancer survivors...
October 19, 2018: Breast Cancer Research: BCR
https://www.readbyqxmd.com/read/30340198/underlying-causes-of-pm-2-5-induced-premature-mortality-and-potential-health-benefits-of-air-pollution-control-in-south-and-southeast-asia-from-1999-to-2014
#6
Yusheng Shi, Aimei Zhao, Tsuneo Matsunaga, Yasushi Yamaguchi, Shuying Zang, Zhengqiang Li, Tao Yu, Xingfa Gu
Quantification of spatial and temporal variations in premature mortality attributable to PM2.5 has important implications for air quality control in South and Southeast Asia (SSEA). The number of PM2.5 -induced premature deaths during 1999-2014 in SSEA was estimated using an integrated exposure-response model based on 0.01° × 0.01° satellite-retrieved PM2.5 data, population density, and spatially and temporally variable baseline mortality data. The results showed extremely high premature death rates in North India and Bangladesh...
October 16, 2018: Environment International
https://www.readbyqxmd.com/read/30339660/exercise-induced-changes-in-soluble-st2-concentrations-in-marathon-runners
#7
Vincent L Aengevaeren, Roland R J VAN Kimmenade, Maria T E Hopman, Niels VAN Royen, James V Snider, James L Januzzi, Keith P George, Thijs M H Eijsvogels
PURPOSE: Previous studies have suggested that extreme endurance exercise may induce cardiac micro-damage that could lead to subsequent myocardial fibrosis. Soluble suppression of tumorigenicity (sST2) is a cardiac biomarker for assessment of myocardial fibrosis, inflammation and strain. We evaluated baseline and exercise-induced sST2 concentrations in a heterogeneous cohort of marathon runners to identify predictors for sST2 concentrations. METHODS: Ninety-two runners supplied demographic data, health status, physical activity levels and marathon experience...
October 18, 2018: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/30338951/association-between-heart-rhythm-and-cortical-sound-processing
#8
Renata S Marcomini, Ana Claúdia F Frizzo, Viviane B de Góes, Simone F Regaçone, David M Garner, Rodrigo D Raimundo, Fernando R Oliveira, Vitor E Valenti
Processing of sound signals is an important factor for conscious human communication and such sound signals may be assessed through cortical auditory evoked potentials. Heart rate variability provides information about heart rate autonomic regulation. The association between resting heart rate variability and cortical auditory evoked potentials was investigated. Resting heart rate variability in the time and frequency domain and the cortical auditory evoked potential components were investigated. Subjects remained at rest for 10 minutes for recording of heart rate variability...
August 15, 2018: Journal of Integrative Neuroscience
https://www.readbyqxmd.com/read/30338020/the-predictability-of-peak-oxygen-consumption-using-submaximal-ratings-of-perceived-exertion-in-adolescents
#9
Danilo V Tolusso, Ward C Dobbs, Michael R Esco
Rating of perceived exertion (RPE) extrapolation involves mathematically extending the submaximal relationship between RPE and oxygen consumption (VO2 ) to maximal intensity. This technique allows practitioners to forego, potentially dangerous, maximal exertion testing while attaining accurate measures of maximal oxygen consumption used for exercise prescription. This method has been proven accurate in adults, but much less in known when applied to an adolescent population. The purpose of this study was to assess the accuracy of the RPE extrapolation as method for estimating VO2max in adolescents...
2018: International Journal of Exercise Science
https://www.readbyqxmd.com/read/30337883/physiozoo-a-novel-open-access-platform-for-heart-rate-variability-analysis-of-mammalian-electrocardiographic-data
#10
Joachim A Behar, Aviv A Rosenberg, Ido Weiser-Bitoun, Ori Shemla, Alexandra Alexandrovich, Eugene Konyukhov, Yael Yaniv
Background: The time variation between consecutive heartbeats is commonly referred to as heart rate variability (HRV). Loss of complexity in HRV has been documented in several cardiovascular diseases and has been associated with an increase in morbidity and mortality. However, the mechanisms that control HRV are not well understood. Animal experiments are the key to investigating this question. However, to date, there are no standard open source tools for HRV analysis of mammalian electrocardiogram (ECG) data and no centralized public databases for researchers to access...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/30337153/affective-and-physiological-reactivity-to-emotional-comments-in-individuals-at-elevated-risk-for-psychosis
#11
Marc J Weintraub, Amy Weisman de Mamani, William J Villano, Travis C Evans, Zachary B Millman, Jill M Hooley, Kiara R Timpano
BACKGROUND: Individuals with schizophrenia are at increased risk of relapse when they live in highly critical (i.e., high expressed emotion; EE) family environments. It remains less clear, however, how individuals at elevated risk for a psychotic disorder react to the social stress of EE. Here we examined whether individuals at elevated risk for developing schizophrenia report greater subjective changes in affect and have increased physiological reactivity after hearing critical, praising and neutral comments...
October 15, 2018: Schizophrenia Research
https://www.readbyqxmd.com/read/30337081/prediction-of-paroxysmal-atrial-fibrillation-a-machine-learning-based-approach-using-combined-feature-vector-and-mixture-of-expert-classification-on-hrv-signal
#12
Elias Ebrahimzadeh, Maede Kalantari, Mohammadamin Joulani, Reza Shahrokhi Shahraki, Farahnaz Fayaz, Fereshteh Ahmadi
BACKGROUND AND OBJECTIVE: Paroxysmal Atrial Fibrillation (PAF) is one of the most common major cardiac arrhythmia. Unless treated timely, PAF might transform into permanent Atrial Fibrillation leading to a high rate of morbidity and mortality. Therefore, increasing attention has been directed towards prediction of PAF, to enable early detection and prevent further progression of the disease. Notwithstanding the pharmacological and electrical treatments, a validated method to predict the onset of PAF is yet to be developed...
October 2018: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/30336749/effects-of-9-months-of-martial-arts-training-on-cardiac-autonomic-modulation-in-healthy-children-and-adolescents
#13
Vinícius Y B Suetake, Emerson Franchini, Bruna T C Saraiva, Anne K F da Silva, Aline F B Bernardo, Rayane L Gomes, Luiz Carlos M Vanderlei, Diego G D Christofaro
PURPOSE: The aim of the study was to evaluate the cardiac autonomic modulation after 9 months of martial arts practice in healthy children and adolescents. METHOD: The study included 59 children and adolescents who were divided into 3 groups: judo, Muay Thai, and control. Heart rate variability was measured by a heart rate monitor, model Polar RS800CX. The intervention occurred twice a week on nonconsecutive days, lasting 60 minutes each session. A 1-way analysis of variance was used to compare participants at baseline...
October 18, 2018: Pediatric Exercise Science
https://www.readbyqxmd.com/read/30336421/ultra-short-term-heart-rate-variability-as-a-tool-to-assess-changes-in-valence
#14
Arjen Schippers, Bart Aben, Yannick Griep, Frank Van Overwalle
Heart rate variability (HRV) is a tool that has been extensively used in fields such as clinical cardiology, psychiatry, and psychology to assess affective experiences. Although traditionally The European Society of Cardiology and The North American Society of Pacing and Electrophysiology recommended to use either a recording length of 24-h (long-term) or five minutes (short-term), recent advances in the field have suggested the use of ultra-short term (<5 min) HRV measurements. In this study, we investigated whether ultra-short term HRV measurements can be used to investigate the temporal dynamics of experimentally induced emotions using pictures from the International Affective Picture System...
October 6, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/30335812/associations-of-sympathetic-and-parasympathetic-activity-in-job-stress-and-burnout-a-systematic-review
#15
P C de Looff, L J M Cornet, P J C M Embregts, H L I Nijman, H C M Didden
This systematic review examines the relationship between sympathetic and parasympathetic activity on the one hand and job stress and burnout on the other, and is registered at PROSPERO under CRD42016035918. BACKGROUND: Previous research has shown that prolonged job stress may lead to burnout, and that differences in heart rate variability are apparent in people who have heightened job stress. AIMS: In this systematic review, the associations between job stress or burnout and heart rate (variability) or skin conductance are studied...
2018: PloS One
https://www.readbyqxmd.com/read/30335610/comparative-study-on-effect-of-neutral-spinal-bath-and-neutral-spinal-spray-on-blood-pressure-heart-rate-and-heart-rate-variability-in-healthy-volunteers
#16
Arundhati Goley, A Mooventhan, N K Manjunath
Background Hydrotherapeutic applications to the head and spine have shown to improve cardiovascular and autonomic functions. There is lack of study reporting the effect of either neutral spinal bath (NSB) or neutral spinal spray (NSS). Hence, the present study was conducted to evaluate and compare the effects of both NSB and NSS in healthy volunteers. Methods Thirty healthy subjects were recruited and randomized into either neutral spinal bath group (NSBG) or neutral spinal spray group (NSSG). A single session of NSB, NSS was given for 15 min to the NSBG and NSSG, respectively...
October 17, 2018: Journal of Complementary & Integrative Medicine
https://www.readbyqxmd.com/read/30334688/the-role-of-nighttime-heart-rate-variability-to-detect-white-matter-hyperintensities-of-presumed-vascular-origin-in-community-dwelling-older-adults
#17
Oscar H Del Brutto, Robertino M Mera, Ernesto Peñaherrera
No abstract text is available yet for this article.
October 18, 2018: International Journal of Stroke: Official Journal of the International Stroke Society
https://www.readbyqxmd.com/read/30333794/different-heart-rate-patterns-during-cardio-pulmonary-exercise-cpx-testing-in-individuals-with-type-1-diabetes
#18
Othmar Moser, Gerhard Tschakert, Alexander Mueller, Werner Groeschl, Max L Eckstein, Gerd Koehler, Richard M Bracken, Thomas R Pieber, Peter Hofmann
To investigate the heart rate during cardio-pulmonary exercise (CPX) testing in individuals with type 1 diabetes (T1D) compared to healthy (CON) individuals. Fourteen people (seven individuals with T1D and seven CON individuals) performed a CPX test until volitional exhaustion to determine the first and second lactate turn points (LTP1 and LTP2 ), ventilatory thresholds (VT1 and VT2 ), and the heart rate turn point. For these thresholds cardio-respiratory variables and percentages of maximum heart rate, heart rate reserve, maximum oxygen uptake and oxygen uptake reserve, and maximum power output were compared between groups...
2018: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/30333366/negative-lusitropic-property-of-nifekalant-identified-using-ventricular-pressure-volume-loop-analyses-in-anesthetized-monkeys
#19
Tomomichi Ishizaka, Yu Yoshimatsu, Yu Maeda, Katsuyoshi Chiba, Kazuhiko Mori
The present study was conducted to clarify multiple cardiohemodynamic and electrophysiological properties including inotropic/lusitropic effects of nifekalant, a class III antiarrhythmic drug, in an isoflurane-anesthetized monkey. Nifekalant was administered intravenously at the therapeutic dose of 0.3 mg/kg over 10 minutes to male cynomolgus monkeys (n=4), followed by higher dose of 1 (n=3) or 3 mg/kg (n=1) that was limited due to arrythmogenicity. Left ventricular (LV) pressure-volume (PV) analysis revealed that the 0...
October 17, 2018: Experimental Animals
https://www.readbyqxmd.com/read/30333014/the-effects-of-yoga-and-quiet-rest-on-subjective-levels-of-anxiety-and-physiological-correlates-a-2-way-crossover-randomized-trial
#20
Kembra Albracht-Schulte, Jacalyn Robert-McComb
BACKGROUND: Rest or acute exercise can decrease state anxiety, with some evidence showing exercise to prevent laboratory-induced elevations in anxiety. No study has examined whether yoga provides short-term protection against laboratory-induced anxiety. The aim of this study was to examine the effectiveness of an acute YogaFit session on state anxiety and measures of heart rate variability (HRV) to determine whether yoga provides short-term protection against emotional picture stimuli...
October 17, 2018: BMC Complementary and Alternative Medicine
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