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diabetic classification

Junhui Xie, Shuhong Hu
Low-density lipoprotein (LDL) cholesterol (LDL-C) always underestimates the true cholesterol burden in diabetic patients. We aimed to explore the impact of the inclusion of apolipoprotein B (apoB) or non-high-density lipoprotein (HDL) cholesterol (non-HDL-C), which are alternative markers of LDL-related risk, results in a better classification of glycated hemoglobin (HbA1c)-defined diabetic patients into different dyslipidemic phenotypes.We used data from the nationwide China Health and Nutrition Survey 2009 in which standardized HbA1c was measured...
October 2018: Medicine (Baltimore)
Feng Wang, Chen Meng, Xing-Bing Cao, Qi Chen, Xiao-Feng Xu, Qian Chen
OBJECTIVE: To discuss the hemiarthroplasty for the threatment of femoral intertrochanteric fracture in elderly patients. METHODS: From August 2013 to January 2017, 66 elderly patients with complicated femoral intertrochanteric fracture were treated including 20 males and 46 females with an average age of 85 years old ranging from 80 to 95. According to improve Evans classification, 33 cases were type III, 24 cases were type IV, 9 cases were type V. History included 31 cases of hypertension, 10 cases of diabetes, 12 cases of severe osteoporosis, 5 cases of atrial fibrillation, 3 cases of pulmonary heart disease, and 1 case of multiple myeloma...
September 25, 2018: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
Kamal Gholipour, Mohammad Asghari-Jafarabadi, Shabnam Iezadi, Ali Jannati, Sina Keshavarz
Background: Type 2 diabetes mellitus (T2DM) is a metabolic disease with complex causes, manifestations, complications and management. Understanding the wide range of risk factors for T2DM can facilitate diagnosis, proper classification and cost-effective management of the disease. Aims: To compare the power of an artificial neural network (ANN) and logistic regression in identifying T2DM risk factors. Methods: This descriptive and analytical study was conducted in 2013...
October 10, 2018: Eastern Mediterranean Health Journal, la Revue de Santé de la Méditerranée Orientale
Surya N Mulukutla, Maria Acevedo-Calado, Christiane S Hampe, Massimo Pietropaolo, Ashok Balasubramanyam
OBJECTIVE: Autoantibodies directed against tyrosine phosphatase IA-2 antibody (IA-2 Ab) are diagnostic for autoimmune type 1 diabetes. Conventional assays target the intracellular domain of IA-2. Among patients with ketosis-prone diabetes (KPD), characterized by presentation with diabetic ketoacidosis (DKA), >60% of adults lack three classic islet autoantibodies-IA-2, GAD65, and ZnT8 Abs-associated with type 1 diabetes. We aimed to determine whether apparently autoantibody-negative ("A-") KPD patients possess occult IA-2 Ab directed against full-length IA-2 (IA-2FL) or its extracellular domain (IA-2EC)...
October 16, 2018: Diabetes Care
Minhaj Alam, Devrim Toslak, Jennifer I Lim, Xincheng Yao
Purpose: This study aimed to develop a method for automated artery-vein classification in optical coherence tomography angiography (OCTA), and to verify that differential artery-vein analysis can improve the sensitivity of OCTA detection and staging of diabetic retinopathy (DR). Methods: For each patient, the color fundus image was used to guide the artery-vein differentiation in the OCTA image. Traditional mean blood vessel caliber (m-BVC) and mean blood vessel tortuosity (m-BVT) in OCTA images were quantified for control and DR groups...
October 1, 2018: Investigative Ophthalmology & Visual Science
Grace Xiong, Chase G Bennett, Loretta Chou, Robin N Kamal
BACKGROUND: Quality measures may be operationalized in payment models or quality reporting programs to assess foot and ankle surgeons, but if existing measures allow accurate representation of a foot and ankle surgeon's practice is unclear. METHODS: National quality measures databases, clinical guidelines, and MEDLINE/PubMed were systematically reviewed for quality measures relevant to foot and ankle care. Measures meeting internal criteria were categorized by clinical diagnosis, National Quality Strategy priority, and Donabedian domain...
October 15, 2018: Journal of the American Academy of Orthopaedic Surgeons
Patrick J Buchanan, Tsun Law, Sam Rosas, Zachary Hubbard, Bruce A Mast, Harvey Chim
BACKGROUND: Diabetes mellitus is a well-known risk factor for infection after trigger finger (TF) injection and/or release. However, the effect of preoperative hypoglycemia before TF injection or release is currently unknown. The purpose of this study is to determine the effects of preoperative hypoglycemia on infection incidence after TF injection or release. METHODOLOGY: A retrospective cohort review between 2007 and 2015 was conducted using a national private payer database within the PearlDiver Supercomputer...
October 15, 2018: Annals of Plastic Surgery
Temel Tirkes, Zarine K Shah, Naoki Takahashi, Joseph R Grajo, Stephanie T Chang, Sudhakar K Venkatesh, Darwin L Conwell, Evan L Fogel, Walter Park, Mark Topazian, Dhiraj Yadav, Anil K Dasyam
Chronic pancreatitis is an inflammatory condition of the pancreas with clinical manifestations ranging from abdominal pain, acute pancreatitis, exocrine and/or endocrine dysfunction, and pancreatic cancer. There is a need for longitudinal studies in well-phenotyped patients to ascertain the utility of cross-sectional imaging findings of chronic pancreatitis for diagnosis and assessment of disease severity. CT and MR cholangiopancreatography are the most common cross-sectional imaging studies performed for the evaluation of chronic pancreatitis...
October 16, 2018: Radiology
Antonio Furlan, Roberto Stramare
PURPOSE: To investigate the frequency of thickening of pulleys for flexor tendons in patients with early arthritis in their hands, and to evaluate it as a predictive sign of PsA. METHODS: A prospective observational study involving 228 consecutive patients presenting with recent onset of arthritis in their hands was conducted at rheumatology outpatient clinics in the Veneto region of Italy between October 2014 and September 2017. Diabetic patients were excluded because of the high frequency of trigger finger...
October 15, 2018: Journal of Ultrasound
Eliane C Jorge, Edson N Jorge, Mayra Botelho, Joyce G Farat, Gianni Virgili, Regina El Dib
BACKGROUND: Diabetic macular oedema (DMO) is a complication of diabetic retinopathy and one of the most common causes of visual impairment in people with diabetes. Clinically significant macular oedema (CSMO) is the most severe form of DMO. Intravitreal antiangiogenic therapy is now the standard treatment for DMO involving the centre of the macula, but laser photocoagulation is still used in milder or non-central DMO. OBJECTIVES: To access the efficacy and safety of laser photocoagulation as monotherapy in the treatment of diabetic macular oedema...
October 15, 2018: Cochrane Database of Systematic Reviews
Wendell C Taylor, Richard R Suminski, Bhibha M Das, Raheem J Paxton, Derek W Craig
Background: Time spent in sedentary behaviors is an independent risk factor for several chronic diseases (e.g., cardiometabolic diseases, obesity, type 2 diabetes, and hypertension). Recently, interventions to reduce sitting time at work (a prominent sedentary behavior) have been developed and tested. Organizational culture plays a critical role in the success of workplace interventions. However, there are a limited number of studies that have examined the role of organizational culture in reducing sitting time in the workplace...
2018: Frontiers in Public Health
Marjoleine F Broekema, Maarten P G Massink, Joep De Ligt, Edwin C A Stigter, Houshang Monajemi, Jeroen De Ridder, Boudewijn M T Burgering, Gijs W van Haaften, Eric Kalkhoven
Genetic lipodystrophies are a group of rare syndromes associated with major metabolic complications - including severe insulin resistance, type 2 diabetes mellitus, and hypertriglyceridemia - which are classified according to the distribution of adipose tissue. Lipodystrophies can be present at birth or develop during life and can range from local to partial and general. With at least 18 different genes implicated so far, definite diagnosis can be challenging due to clinical and genetic heterogeneity. In an adult female patient with clinical and metabolic features of partial lipodystrophy we identified via whole genome sequencing (WGS) a single complex AGPAT2 allele [V67M;V167A], functionally equivalent to heterozygosity...
2018: Frontiers in Physiology
Yan-Zhe Wang, Ding-Yu Zhu, Xin-Miao Xie, Miao Ding, Yong-Lan Wang, Lin-Lin Sun, Nan Zhang, E Shen, Xiao-Xia Wang
This study aimed to investigate the molecular mechanisms of diabetic kidney disease (DKD) and to explore new potential therapeutic strategies and biomarkers for DKD. First we analyzed the differentially expressed changes between patients with DKD and the control group using the chip data in Gene Expression Omnibus (GEO) database. Then the gene chip was subjected to be annotated again, so as to screen long noncoding RNAs (lncRNAs) and study expression differences of these lncRNAs in DKD and controlled samples...
October 14, 2018: Journal of Cellular Physiology
Christina W Cheng, Amy M Cizik, Armagan H C Dagal, Larissa Lewis, John Lynch, Carlo Bellabarba, Richard J Bransford, Haitao Zhou
BACKGROUND: Surgical site infection (SSI) following spine surgery is associated with increased morbidity, reoperation rates, hospital readmissions and cost. The incidence of SSI following posterior cervical spine surgery is higher than anterior cervical spine surgery, with rates from 4.5-18%. It is well documented that higher body mass index (BMI) is associated with increased risk of SSI after spine surgery. There are only a few studies that examine the correlation of BMI and SSI after posterior cervical instrumented fusion (PCIF) using national databases, however, none that compare trauma and non-traumatic patients...
October 10, 2018: Spine Journal: Official Journal of the North American Spine Society
Yi-Jing Sheen, Pei-Tseng Kung, Wei-Yin Kuo, Li-Ting Chiu, Wen-Chen Tsai
Patients with diabetes are at a high risk of lower extremity amputations and may have a reduced life expectancy. Taiwan has implemented a diabetes pay-for-performance (P4P) program providing team care to improve the control of disease and avoid subsequent complications. Few studies investigated the effects of adopting a nationalized policy to decrease amputation risk in diabetes previously. Our study aimed to analyze the impact of the P4P programs on the incidence of lower extremity amputations in Taiwanese patients with diabetes...
October 2018: Medicine (Baltimore)
Fernando Luis Bernal Páez, Miguel Alcaraz Baños, Jose Manuel Felices Abad, Ana Bernal Belmonte, Gabriel Gijon-Nogueron, Manuel Pardo Rios
To assess the quality of life (QoL) of treated patients in order to evaluate the success of peripheral transluminal angioplasty (PTA) and correlate physical parameters with clinical progress at 6 months post-PTA.According to TASC II classifications, 69 patients were selected for PTA. Clinical evaluation and diagnostic tests were performed before, after and after 6 months following PTA. The SF-36 QoL questionnaire was added as an additional parameter.Fifty one patients were included in the study. The ankle-brachial index (ABI) increased from 0...
October 2018: Medicine (Baltimore)
Reza Dana, John L Bradley, Annie Guerin, Irina Pivneva, Amber M Evans, Ipek Özer Stillman
PURPOSE: To assess the proportion of comorbidities in patients with dry eye disease (DED) compared with matched patients without DED in a comprehensive US population. DESIGN: Retrospective case-control study METHODS: Health care records for insurance claims data, detailing medical services incurred by military personnel, their families and dependents in military and civilian facilities across the United States from January 1, 2003 to March 31, 2015, were obtained from the Department of Defense (DOD) Military Health System (MHS)...
October 9, 2018: American Journal of Ophthalmology
Jakob Grauslund, Nis Andersen, Jens Andresen, Per Flesner, Per Haamann, Steffen Heegaard, Michael Larsen, Caroline Schmidt Laugesen, Katja Schielke, Jesper Skov, Toke Bek
PURPOSE: Diabetic retinopathy (DR) is among the leading causes of visual loss in the working-age population. It is generally accepted that screening of DR is cost-effective and can detect DR before it becomes sight-threatening to allow timely treatment. METHODS: A group of retinal specialists was formed by the Danish Ophthalmological Society with the aim to formulate contemporary evidence-based guidelines for screening of DR in order to implement these in the Danish screening system...
October 11, 2018: Acta Ophthalmologica
Prasanna Porwal, Samiksha Pachade, Manesh Kokare, Luca Giancardo, Fabrice Mériaudeau
Age-related Macular Degeneration (AMD) and Diabetic Retinopathy (DR) are the most prevalent diseases responsible for visual impairment in the world. This work investigates discrimination potential in the texture of color fundus images to distinguish between diseased and healthy cases by avoiding the prior lesion segmentation step. It presents a retinal background characterization approach and explores the potential of Local Tetra Patterns (LTrP) for texture classification of AMD, DR and Normal images. Five different experiments distinguishing between DR - normal, AMD - normal, DR - AMD, pathological - normal and AMD - DR - normal cases were conducted and validated using the proposed approach, and promising results were obtained...
October 1, 2018: Computers in Biology and Medicine
Chen-Wei Pan, Shan Wang, Cai-Lian Xu, E Song
Background: To explore the associations of glycemic and blood pressure (BP) control with diabetic retinopathy (DR), with special focus on whether different combinations of categories of these two interventions are additive. Methods: A community-based survey including 913 patients with known type-2 diabetes mellitus (T2DM) was conducted in Suzhou, China. Retinal photographs were graded for the presence of DR using the Airlie House classification system. BP and blood hemoglobin A1c (HbA1C) levels were measured by standardized protocols...
2018: Diabetology & Metabolic Syndrome
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