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https://www.readbyqxmd.com/read/29906790/strategies-for-linkage-to-and-engagement-with-care-focus-on-intervention
#1
Thomas P Giordano
Retention of HIV-infected patients in care is crucial to optimizing individual patient outcomes and reducing transmission of HIV. A number of strategies are available to improve linkage to care; among them, the AntiRetroviral Treatment and Access Services intervention should be considered standard of care at the clinic level. With regard to retention in care, the Retention Through Enhanced Personal Contact intervention has been shown to improve retention rates and the Centers for Disease Control and Prevention Data to Care program has been successful in assisting public health authorities to locate and return to treatment patients presumed to be lost to follow-up...
June 2018: Topics in Antiviral Medicine
https://www.readbyqxmd.com/read/29906789/new-and-noteworthy-in-tuberculosis-diagnostics-and-treatment
#2
Susan Swindells
People with HIV infection with latent tuberculosis (TB) infection (LTBI) are at a 10-fold greater risk of developing active disease. Interferon gamma release assays and tuberculin skin testing have approximately 65% to 70% specificity for diagnosing LTBI in HIV-infected patients. LTBI can be successfully treated with isoniazid preventive therapy and early antiretroviral therapy (ART). Rapid molecular diagnostics have approximately 88% sensitivity and 98% specificity for identifying active TB. ART should be started early in patients with TB...
June 2018: Topics in Antiviral Medicine
https://www.readbyqxmd.com/read/29906784/communication-errors-in-radiology-pitfalls-and-how-to-avoid-them
#3
REVIEW
Stephen Waite, Jinel Moore Scott, Ian Drexler, Jennifer Martino, Alan Legasto, Brian Gale, Srinivas Kolla
Communication failures are a common cause of patient harm and malpractice claims against radiologists. In addition to overt communication breakdowns among providers, it is also important to address the quality of communication to optimize patient outcomes. In this review, we describe common communication failures and potential solutions providing a framework for radiologists to improve health care delivery.
June 7, 2018: Clinical Imaging
https://www.readbyqxmd.com/read/29906741/group-medical-consultations-gmcs-and-tablet-based-online-support-group-sessions-in-the-follow-up-of-breast-cancer-a-multicenter-randomized-controlled-trial
#4
Annemiek Visser, Judith B Prins, Lisette Jansen, Sandra A Radema, Margrethe S Schlooz, Thijs van Dalen, Hanneke W M van Laarhoven
OBJECTIVE: Group medical consultations (GMCs) provide individual medical visits in the presence of ≤7 peer-patients. In the follow-up of breast cancer, we evaluated the efficacy of a new type of blended care My-GMC, a GMC combined with a tablet-based online app, consisting of three online support group sessions (SGS) and additional information. METHODS: This randomized controlled trial compared the effect of My-GMC (n = 59) with one individual medical visit (n = 50) (care as usual)...
June 12, 2018: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/29906700/patient-characteristics-and-treatment-patterns-in-patients-with-newly-diagnosed-epilepsy-a-us-database-analysis
#5
Edward Faught, Sandra Helmers, David Thurman, Hyunmi Kim, Linda Kalilani
OBJECTIVE: The objective of this study was to determine patient characteristics and antiepileptic drug (AED) treatment patterns in patients with newly diagnosed epilepsy in a United States (US) population followed for ≥180 days. METHODS: In this retrospective cohort study, Commercial, Supplemental Medicare, and Medicaid insurance claims from US-based Truven Health MarketScan® claims database were analyzed for incident epilepsy cases (index date: January 2010-June 2013; prior baseline of 2 years [1 year for ages 1 to <2 years; none for those <1 year])...
June 12, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29906667/the-high-cost-of-critical-care-unit-over-utilization-for-patients-with-nste-acs
#6
Sean van Diepen, Dat T Tran, Justin A Ezekowitz, David A Zygun, Jason N Katz, Renato D Lopes, L Kristin Newby, Finlay A McAlister, Padma Kaul
BACKGROUND: There is substantial variability among hospitals in critical care unit (CCU) utilization for patients admitted with non-ST-Segment Elevation Acute Coronary Syndromes (NSTE ACS). We estimated the potential cost saving if all hospitals adopted low CCU utilization practices for patients with NSTE ACS. METHODS: National hospital claims data were used to identify all patients with a primary diagnosis of NSTE ACS initially admitted to an acute care hospital between 2007 and 2013...
May 19, 2018: American Heart Journal
https://www.readbyqxmd.com/read/29906642/the-effect-of-simethicone-on-postoperative-ileus-in-patients-undergoing-colorectal-surgery-spot-a-randomized-controlled-trial
#7
Jeremy E Springer, Shiraz Elkheir, Cagla Eskicioglu, Aristithes G Doumouras, Stephen Kelly, Ilun Yang, Shawn Forbes
BACKGROUND: Postoperative ileus is a poorly understood multifactorial outcome following colorectal surgery that presents significant clinical challenges and contributes to increased morbidity, length of stay, and healthcare cost. To date, there are few pharmacological interventions that shorten the duration of postoperative ileus. OBJECTIVE: This study is the first to evaluate the efficacy of simethicone in treating postoperative ileus symptoms in patients undergoing colorectal surgery...
June 12, 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/29906612/nad-and-sirtuins-in-retinal-degenerative-diseases-a-look-at-future-therapies
#8
REVIEW
Jonathan B Lin, Rajendra S Apte
Retinal degenerative diseases are a major cause of morbidity in modern society because visual impairment significantly decreases the quality of life of patients. A significant challenge in treating retinal degenerative diseases is their genetic and phenotypic heterogeneity. However, despite this diversity, many of these diseases share a common endpoint involving death of light-sensitive photoreceptors. Identifying common pathogenic mechanisms that contribute to photoreceptor death in these diverse diseases may lead to a unifying therapy for multiple retinal diseases that would be highly innovative and address a great clinical need...
June 12, 2018: Progress in Retinal and Eye Research
https://www.readbyqxmd.com/read/29906597/saliva-as-a-diagnostic-specimen-for-testing-respiratory-virus-by-a-point-of-care-molecular-assay-a-diagnostic-validity-study
#9
Kelvin Kw To, Cyril Cy Yip, Cherie Yw Lai, Carlos Kh Wong, Deborah Ty Ho, Polly Kp Pang, Anthony Ck Ng, Kit-Hang Leung, Rosana Ws Poon, Kwok-Hung Chan, Vincent Cc Cheng, Ivan Fn Hung, Kwok-Yung Yuen
OBJECTIVES: Automated point-of-care molecular assays have greatly shortened the turnaround time of respiratory virus testing. One of the major bottlenecks now lies at the step of the specimen collection especially in a busy clinical setting. Saliva is a convenient specimen type which can be provided easily from adult patients. This study assessed the diagnostic validity, specimen collection time, and cost associated with the use of saliva. METHODS: This was a prospective diagnostic validity study comparing the detection rate of respiratory viruses between saliva and nasopharyngeal aspirate (NPA) among adult hospitalized patients using Xpert® Xpress Flu/RSV...
June 12, 2018: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/29906596/are-we-missing-respiratory-viral-infections-in-infants-and-children-comparison-of-a-hospital-based-quality-management-system-with-standard-of-care
#10
Maren Alchikh, Tim Conrad, Christian Hoppe, Xiaolin Ma, Eeva Broberg, Pasi Penttinen, Janine Reiche, Barbara Biere, Brunhilde Schweiger, Barbara Rath
OBJECTIVES: Hospital-based surveillance of influenza and acute respiratory infections relies on ICD-codes and hospital laboratory reports (Standard-of-Care). It is unclear how many cases are missed with either method, i.e. remain undiagnosed/coded as influenza and other respiratory virus infections. Various influenza-like illness (ILI) definitions co-exist with little guidance on how to use them. We are comparing the diagnostic accuracy of standard surveillance methods with a prospective quality management (QM-Program) at a Berlin children's hospital with the Robert-Koch-Institute (RKI)...
June 12, 2018: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/29906594/diagnostic-accuracy-of-a-prototype-rapid-chlamydia-and-gonorrhoea-recombinase-polymerase-amplification-assay-a-multi-centre-cross-sectional-pre-clinical-evaluation
#11
Emma M Harding-Esch, Sebastian S Fuller, S-L Christine Chow, Achyuta V Nori, Mark A Harrison, Mathew Parker, Olaf Piepenburg, Matthew S Forrest, David G Brooks, Rajul Patel, Phillip Hay, Nicola Fearnley, Marcus J Pond, J Kevin Dunbar, Philip D Butcher, Timothy Planche, Catherine M Lowndes, S Tariq Sadiq
OBJECTIVES: Rapid and accurate sexually transmitted infection diagnosis can reduce onward transmission and improve treatment efficacy. We evaluated the accuracy of a 15-minute run-time recombinase polymerase amplification (RPA)-based prototype point-of-care test (TwistDx) for Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG). METHODS: Prospective, multi-centre study of symptomatic and asymptomatic patients attending three English sexual health clinics. Research samples provided were: additional self-collected vulvo-vaginal swab (SCVS) (females); first-catch urine (FCU) aliquot (females and males)...
June 12, 2018: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/29906434/incorporating-biomarkers-into-the-primary-prostate-biopsy-setting-a-cost-effectiveness-analysis
#12
Niranjan J Sathianathen, Karen M Kuntz, Fernando Alarid-Escudero, Nathan L Lawrentschuk, Damien M Bolton, Declan G Murphy, Christopher J Weight, Badrinath R Konety
PURPOSE: To perform a cost-effectiveness analysis of using Prostate Health Index (PHI), 4Kscore, SelectMDx and ExoDx Prostate IntelliScore (EPI) in men with an elevated PSA value to determine the need for biopsy. METHODS: We developed a decision-analytic model for men with an elevated PSA values (≥ 3ng/mL) where one of the biomarker tests was to determine which hypothetical individuals required a biopsy. In the current standard of care strategy, all individuals underwent a biopsy...
June 12, 2018: Journal of Urology
https://www.readbyqxmd.com/read/29906429/death-or-debt-national-estimates-of-financial-toxicity-in-persons-with-newly-diagnosed-cancer
#13
Adrienne M Gilligan, David S Alberts, Denise J Roe, Grant H Skrepnek
PURPOSE: To evaluate the impact of cancer upon a patient's depletion of net worth and incursion of debt in the U.S. METHODS: This longitudinal study used the Health and Retirement Study (HRS) from 1998-2014. Persons ≥50 years with newly-diagnosed malignancies were included, excluding minor skin cancers. Multivariable generalized linear models were employed to assess changes in net worth and debt (consumer, mortgage, home equity) at two-and four-years following diagnosis (Year+2 , Year+4 ) after controlling for demographic and clinically-related variables, cancer-specific attributes, economic factors, and mortality...
June 12, 2018: American Journal of Medicine
https://www.readbyqxmd.com/read/29906420/invited-commentary-on-the-report-to-congress-on-the-management-of-traumatic-brain-injury-in-children
#14
Stacy J Suskauer, Amy J Houtrow
The Centers for Disease Control and Prevention published the "Report to Congress on the Management of Traumatic Brain Injury in Children" in the spring of 2018. The report is a call to action for professionals providing care for children with traumatic brain injury in the health, social and educational sectors and for researchers, administrators and agencies to develop strategies to improve outcomes. For pediatric rehabilitation providers there are clear opportunities to improve service delivery for individual patients and for the population of children after traumatic brain injury more generally...
June 12, 2018: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29906408/the-potential-for-liquid-biopsies-in-head-and-neck-cancer
#15
Matthew E Spector, Janice L Farlow, Catherine T Haring, J Chad Brenner, Andrew C Birkeland
Head and neck cancers consist of a heterogeneous group of cancers that are difficult to treat successfully. Limited screening options result in patients being diagnosed at advanced stages at presentation, and difficulty with treatment options and post-treatment surveillance can lead to poor outcomes. In this setting, tools for early and precise detection of disease will be highly valuable. Liquid biopsies, or use of analytes in blood, saliva, and other body fluid samples, provide new avenues for cancer screening with the potential for early detection, treatment modification, and surveillance of head and neck cancers...
May 2018: Discovery Medicine
https://www.readbyqxmd.com/read/29906322/dressings-and-topical-agents-for-treating-venous-leg-ulcers
#16
REVIEW
Gill Norman, Maggie J Westby, Amber D Rithalia, Nikki Stubbs, Marta O Soares, Jo C Dumville
BACKGROUND: Venous leg ulcers are open skin wounds on the lower leg which can be slow to heal, and are both painful and costly. The point prevalence of open venous leg ulcers in the UK is about 3 cases per 10,000 people, and many people experience recurrent episodes of prolonged ulceration. First-line treatment for venous leg ulcers is compression therapy, but a wide range of dressings and topical treatments are also used. This diversity of treatments makes evidence-based decision-making challenging, and a clear and current overview of all the evidence is required...
June 15, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29906305/pilot-evaluation-of-home-delivery-programme-in-haemophilia
#17
J E Megías-Vericat, E Monte-Boquet, M Martín-Cerezuela, M J Cuéllar-Monreal, M V Tarazona-Casany, P Pérez-Huertas, S Bonanad, J L Poveda-Andrés
WHAT IS KNOWN AND OBJECTIVES: Most of the clotting factor (CF) dispensations to haemophiliac patients are centralized in a few haemophilia treatment centres, necessitating frequent visits and long travel distances. The aim was to evaluate the home delivery programme developed by the Outpatient Pharmaceutical Care Unit (OPCU) through the association of patients (ASHECOVA). METHODS: A specific software programme was designed to communicate the individual CF requirements...
June 15, 2018: Journal of Clinical Pharmacy and Therapeutics
https://www.readbyqxmd.com/read/29906268/combined-international-external-quality-assessment-results-of-medical-laboratory-performance-and-reporting-of-samples-with-known-antimicrobial-resistance
#18
Michael A Noble, Robert Rennie
BACKGROUND: Reporting on the presence of antimicrobial resistance is of considerable concern both for individual patient care and for understanding the underlying health status within the community at large. Antimicrobial resistance is solely dependent upon clinical laboratory detection and thus can be impacted upon by the quality and competence of medical laboratories. Proficiency testing or external quality assessment (PT/EQA) is the international standard for the direct measurement of medical laboratory performance on critical testing...
June 15, 2018: Diagnosis
https://www.readbyqxmd.com/read/29906265/transcatheter-mitral-valve-in-valve-and-valve-in-ring-replacement-in-high-risk-surgical-patients-feasibility-safety-and-longitudinal-outcomes-in-a-single-center-experience
#19
Ashleigh Long, Paul Mahoney
BACKGROUND: Transcatheter mitral valve-in-valve (TMVIV) or valve-in-ring (TMVIR) replacement has shown early promise in patients deemed poor surgical candidates as a less invasive alternative to conventional reoperative mitral valve (MV) replacement. OBJECTIVE: This retrospective, single-center study reviewed the procedural outcomes of all TMVIV and TMVIR procedures between 2013-2018 at a large tertiary referral center serving the southeastern United States. An analysis of patient safety measures was also performed, with a retrospective assessment of relative procedural safety that included preoperative risk stratification and postoperative mortality predictors, operative time, average blood loss, length of hospital stay, and readmission rates...
June 15, 2018: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/29906211/the-state-of-oncology-practice-in-america-2018-results-of-the-asco-practice-census-survey
#20
M Kelsey Kirkwood, Amy Hanley, Suanna S Bruinooge, Elizabeth Garrett-Mayer, Laura A Levit, Caroline Schenkel, Jerome E Seid, Blase N Polite, Richard L Schilsky
PURPOSE: To describe the US hematology and medical oncology practice landscape and to report findings of the sixth annual ASCO Oncology Practice Census survey. PARTICIPANTS AND METHODS: ASCO used Medicare Physician Compare data to characterize oncology practices in the United States. Practice size, number of care sites, and geographic distribution were determined. Trends in the number and size of practices from 2013 to 2017 were examined. All US oncology practices were targeted for the survey; survey responses were linked to the practices identified from Physician Compare to augment results and assess generalizability...
June 15, 2018: Journal of Oncology Practice
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