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Tilen Genov, Paul D Jepson, Jonathan L Barber, Ana Hace, Stefania Gaspari, Tina Centrih, Jan Lesjak, Polona Kotnjek
Marine top predators, including marine mammals, are known to bio-accumulate persistent pollutants such as polychlorinated biphenyls (PCBs), a serious conservation concern for these species. Although PCBs declined in European seas since the 1970s-1980s ban, considerable levels still persist in European and Mediterranean waters. In cetaceans, stranded animals are a valuable source of samples for pollutant studies, but may introduce both known and unknown biases. Biopsy samples from live, free-ranging cetaceans offer a better alternative for evaluating toxicological burdens of populations, especially when linked to known histories of identified individuals...
December 4, 2018: Science of the Total Environment
Laura Bolton
Diabetic foot ulcers (DFUs) remain a challenge for clinicians despite decades of study. Clinicians now realize that healing strategies should focus on the patient as well as the ulcer. The search continues for interventions that affected individuals and their care providers can count on to heal and manage these challenging wounds, stopping the dreaded progression to amputation and death. The path to healing a patient's DFU often requires multidisciplinary care, including consistent offloading of insensate areas, endocrinologic and metabolic control, and improved circulation...
December 2018: Wounds: a Compendium of Clinical Research and Practice
Nicole Blanshan, Maren L Mahowald, Christopher Dorman, Sandra Frizelle, Hollis E Krug
PURPOSE: We previously reported the efficacy of intraarticular (IA) rimabotulinumtoxinB (BoNT/B) in a murine model of chronic degenerative arthritis pain. This study aimed to measure the analgesic effects of onabotulinumtoxinA (BoNT/A) on collagenase induced chronic degenerative arthritis joint pain. METHODS: Chronic degenerative arthritis was produced by IA injection of 10 μl collagenase (Col) (10 IU) into the left knee of C57BL/6J female mice 4 weeks prior to pain assessment...
November 21, 2018: Toxicon: Official Journal of the International Society on Toxinology
C N Parker, J J Van Netten, T J Parker, L Jia, H Corcoran, M Garrett, C F Kwok, A Nather, M T Que, G Srisawasdi, P Wraight, P A Lazzarini
AIM: No studies have investigated if national guidelines to manage diabetic foot disease differ from international guidelines. This study aimed to compare guidelines of Western Pacific nations with the International Working Group on the Diabetic Foot (IWGDF) guidance documents. METHODS: The 77 recommendations in five chapters of the 2015 IWGDF guidance documents were used as the international gold standard reference. The IWGDF national representative(s) from 12 Western Pacific nations were invited to submit their nation's diabetic foot guideline(s)...
November 23, 2018: Diabetes/metabolism Research and Reviews
Lei Wu, Muneesh Maheshwari, Yaowen Yang, Wensheng Xiao
With the development in the exploitation of maritime resources, the structural health monitoring (SHM) of offshore structures becomes necessary. This study focuses on addressing the practical issues of application of fiber Bragg grating (FBG) sensors for the SHM of offshore structures, in particular an FPSO (floating, production, storage, and offloading unit) vessel. Due to the harsh marine environment and tough working conditions, the FBG sensors must have sufficient protection and good repeatability for long-term monitoring...
November 15, 2018: Sensors
Alramzana Nujum Navaz, Mohamed Adel Serhani, Nabeel Al-Qirim, Marton Gergely
BACKGROUND AND OBJECTIVES: Mobile and ubiquitous devices are everywhere, generating an exorbitant amount of data. New generations of healthcare systems are using mobile devices to continuously collect large amounts of different types of data from patients with chronic diseases. The challenge with such Mobile Big Data in general, is how to meet the growing performance demands of the mobile resources handling these tasks, while simultaneously minimizing their consumption. METHODS: This research proposes a scalable architecture for processing Mobile Big Data...
November 2018: Computer Methods and Programs in Biomedicine
Rico Valentino, Woo-Sung Jung, Young-Bae Ko
Drones have recently become extremely popular, especially in military and civilian applications. Examples of drone utilization include reconnaissance, surveillance, and packet delivery. As time has passed, drones' tasks have become larger and more complex. As a result, swarms or clusters of drones are preferred, because they offer more coverage, flexibility, and reliability. However, drone systems have limited computing power and energy resources, which means that sometimes it is difficult for drones to finish their tasks on schedule...
November 2, 2018: Sensors
Dien Van Nguyen, Tuan Thanh Le, Sangsoon Lee, Eun-Seok Ryu
360-degree video streaming for high-quality virtual reality (VR) is challenging for current wireless systems because of the huge bandwidth it requires. However, millimeter wave (mmWave) communications in the 60 GHz band has gained considerable interest from the industry and academia because it promises gigabit wireless connectivity in the huge unlicensed bandwidth (i.e., up to 7 GHz). This massive unlicensed bandwidth offers great potential for addressing the demand for 360-degree video streaming. This paper investigates the problem of 360-degree video streaming for mobile VR using the SHVC, the scalable of High-Efficiency Video Coding (HEVC) standard and PC offloading over 60 GHz networks...
November 1, 2018: Sensors
Arnab Chanda, Vinu Unnikrishnan
Around the world, over 400 million people suffer from diabetes. In a chronic diabetic condition, the skin underneath the foot often becomes extremely soft and brittle, resulting in the development of foot ulcers. In literature, a plethora of footwear designs have been developed to reduce the induced stresses on a diabetic foot and to consequently prevent the incidences of foot ulcers. However, to date, no insole design exists which can handle post-ulcer diabetic foot conditions without hindering the mobility of the patients...
November 2, 2018: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
Chandrasekaran Jayaraman, Chaitanya Krishna Mummididetty, Alexandra Loesch, Sandi Kaur, Shenan Hoppe-Ludwig, Manfred Staat, Arun Jayaraman
OBJECTIVE: To investigate the postural and metabolic benefits a walker with adjustable elbow support (LifeWalker (LW)) can provide for ambulation in population with impairment. The clinical outcomes from the elbow support walker will be compared with standard rollator (SR) and participants predicate device (PD). DESIGN: Case-crossover study design SETTING: Clinical laboratory PARTICIPANTS: Individuals aged between 18 and 85 years using a rollator walker as primary mode of assistance and certified as medically stable by their primary physician...
October 24, 2018: Archives of Physical Medicine and Rehabilitation
Vincenzo Bonnici, Federico Busato, Stefano Aldegheri, Murodzhon Akhmedov, Luciano Cascione, Alberto Arribas Carmena, Francesco Bertoni, Nicola Bombieri, Ivo Kwee, Rosalba Giugno
BACKGROUND: R has become the de-facto reference analysis environment in Bioinformatics. Plenty of tools are available as packages that extend the R functionality, and many of them target the analysis of biological networks. Several algorithms for graphs, which are the most adopted mathematical representation of networks, are well-known examples of applications that require high-performance computing, and for which classic sequential implementations are becoming inappropriate. In this context, parallel approaches targeting GPU architectures are becoming pervasive to deal with the execution time constraints...
October 15, 2018: BMC Bioinformatics
Christine A Curcio
AMD is a major cause of legal blindness in older adults approachable through multidisciplinary research involving human tissues and patients. AMD is a vascular-metabolic-inflammatory disease, in which two sets of extracellular deposits, soft drusen/basal linear deposit (BLinD) and subretinal drusenoid deposit (SDD), confer risk for end-stages of atrophy and neovascularization. Understanding how deposits form can lead to insights for new preventions and therapy. The topographic correspondence of BLinD and SDD with cones and rods, respectively, suggest newly realized exchange pathways among outer retinal cells and across Bruch's membrane and the subretinal space, in service of highly evolved, eye-specific physiology...
March 20, 2018: Investigative Ophthalmology & Visual Science
Rachel Schumann
Changes to Ontario's bail system (2017) are intended to keep accused out of custody and in the community as they await trial. For the Ministry of the Attorney General, living in the community while on bail is a vast improvement to remand because there is minimal state involvement in the lives of accused, resulting in fewer personal and administrative disruptions. Yet, most accused in the province require a surety to be released. Justices of the peace, Crowns, and even defense counsel expect sureties to act like civilian jailers, which questions the level of state intervention at this stage in the legal process...
October 23, 2018: Canadian Review of Sociology, Revue Canadienne de Sociologie
Yuan Wu, Xiangxu Chen, Jiajun Shi, Kejie Ni, Liping Qian, Liang Huang, Kuan Zhang
Blockchain has emerged as a decentralized and trustable ledger for recording and storing digital transactions. The mining process of Blockchain, however, incurs a heavy computational workload for miners to solve the proof-of-work puzzle (i.e., a series of the hashing computation), which is prohibitive from the perspective of the mobile terminals (MTs). The advanced multi-access mobile edge computing (MEC), which enables the MTs to offload part of the computational workloads (for solving the proof-of-work) to the nearby edge-servers (ESs), provides a promising approach to address this issue...
October 15, 2018: Sensors
Fahad Ahmad Khan, Sehar Butt, Saad Ahmad Khan, Ladislau Bölöni, Damla Turgut
Sensor nodes in underwater sensor networks may acquire data at a higher rate than their ability to communicate over underwater acoustic channels. Autonomous underwater vehicles may mitigate this mismatch by offloading high volumes of data from the sensor nodes and ferrying them to the sink. Such a mode of data transfer results in high latency. Occasionally, these networks need to report high priority events such as catastrophes or intrusions. In such a scenario the expectation is to have a minimal end-to-end delay for event reporting...
October 11, 2018: Sensors
Nicholas J Zarkadis, Philip J Belmont, Michael A Zachilli, Courtney A Holland, Allison R Kinsler, Michael S Todd, Mark P Pallis, Brian R Waterman
BACKGROUND: The occupational and functional results of patellofemoral autologous chondrocyte implantation (ACI) are underreported. This investigation sought to establish clinical outcomes and rates for return to work in a predominantly high-demand military cohort undergoing this procedure. PURPOSE: To determine the return-to-work, pain relief, and perioperative complication rates in a high-demand athletic cohort undergoing patellofemoral ACI. STUDY DESIGN: Case series; Level of evidence, 4...
November 2018: American Journal of Sports Medicine
David Pascoal Sudaia, Milton Briguet Bastos, Elieti Biques Fernandes, Christine Rabello Nascimento, Elen B A V Pacheco, Ana Lúcia N da Silva
Decommissioning offshore Floating Production, Storage and Offloading (FPSO) platforms requires extensive technical knowledge, since it generates different post-consumer materials, including mooring lines. These ropes are made from polyester high tenacity yarn, based on polyethylene terephthalate (PET), and their high added value means they should not be discarded as scrap. This paper aims to present a review and technical opportunities, from an economic standpoint, of recycling the mooring lines recovered from decommissioned FPSOs...
October 2018: Marine Pollution Bulletin
Haina Zheng, Ke Xiong, Pingyi Fan, Li Zhou, Zhangdui Zhong
This paper studies a simultaneous wireless information and power transfer (SWIPT)-aware fog computing by using a simple model, where a sensor harvests energy and receives information from a hybrid access point (HAP) through power splitting (PS) receiver architecture. Two information processing modes, local computing and fog offloading modes are investigated. For such a system, two optimization problems are formulated to minimize the sensor's required power for the two modes under the information rate and energy harvesting constraints by jointly optimizing the time assignment and the transmit power, as well as the PS ratio...
September 30, 2018: Sensors
Howard D Backer, Nicole T D'Arcy, Adam J Davis, Bruce Barton, Karl A Sporer
OBJECTIVE: Ambulance patient offload time (APOT) also known colloquially as "Wall time" has been described in various jurisdictions but seems to be highly variable. Any attempt to improve APOT requires the use of common definitions and standard methodology to measure the extent of the problem. METHODS: An Ambulance Offload Delay Task Force in California developed a set of standard definitions and methodology to measure APOT for transported 9-1-1 patients...
October 25, 2018: Prehospital Emergency Care
Gustav Jarl
Foot ulcers are a diabetic complication associated with significant morbidity, mortality, and amputation risk. Offloading devices prevent and heal foot ulcers, but adherence to using these devices is low. The reasons for nonadherence are unclear, and study results are difficult to compare due to methodological heterogeneity. This paper explores aspects of investigating adherence to using offloading devices among people with diabetes and provides recommendations for future studies, focusing on study designs, definitions of adherence, measurement methods, and conceptual frameworks...
2018: Patient Preference and Adherence
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