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JOURNAL ARTICLE
Kate E D Ziser, Stephen Wood, George S Q Tan, Jedidiah I Morton, Jonathan E Shaw, J Simon Bell, Jenni Ilomaki
BACKGROUND: We investigated the association between post-hospital discharge use of sodium glucose cotransporter-2 inhibitors (SGLT-2is) compared to dipeptidyl peptidase-4 inhibitors (DPP-4is) and the incidence of hospitalization for acute renal failure (ARF) and chronic kidney disease (CKD) in people with type 2 diabetes. METHODS: We conducted a retrospective cohort study using linked hospital and prescription data. Our cohort included people aged ≥30 years with type 2 diabetes discharged from a hospital in Victoria, Australia, from December 2013 to June 2018...
April 2024: Journal of Diabetes
#22
JOURNAL ARTICLE
Kimberly Souffront, Bret P Nelson, Megan Lukas, Hans Reyes Garay, Lauren Gordon, Thalia Matos, Isabella Hanesworth, Rebecca Mantel, Claire Shubeck, Cassidy Bernstein, George T Loo, Lynne D Richardson
INTRODUCTION: Hypertension is the leading risk factor for morbidity and mortality throughout the world and is pervasive in United States emergency departments (ED). This study documents the point prevalence of subclinical heart disease in emergency patients with asymptomatic hypertension. METHOD: This was a prospective observational study of ED patients with asymptomatic hypertension conducted at two urban academic EDs that belong to an eight-hospital healthcare organization in New York...
March 2024: Western Journal of Emergency Medicine
#23
JOURNAL ARTICLE
Jiun-Lin Yan, Wan-Chin Kan, Yi-Hsien Kuo, Mao-Yu Chen, Pin-Yuan Chen, Kuan-Hao Fu
INTRODUCTION: Transsphenoidal surgery (TSS) is the preferred surgical method for most pituitary adenomas owing to high efficacy and low mortality. This study aimed to evaluate the influence of metabolic syndrome (MetS) on postoperative outcomes of TSS for pituitary adenoma. METHODS: This population-based, retrospective observational study extracted data of adults 20-79 y receiving TSS for pituitary adenoma from the US Nationwide Inpatient Sample (NIS) between 2005-2018...
2024: Frontiers in Endocrinology
#24
JOURNAL ARTICLE
Valerie Danesh, Alaina Tellson, Leanne M Boehm, Alan B Stevens, Gerald O Ogola, Anisha Shrestha, Jinmyoung Cho, Edgar J Jimenez, Alejandro C Arroliga
BACKGROUND: Despite the variability and complexity of geriatric conditions, few COVID-19 reports of clinical characteristic prognostication provide data specific to oldest-old adults (over age 85), and instead generally report broadly as 65 and older. OBJECTIVE: To examine metabolic syndrome criteria in adults across 25 hospitals with variation in chronological age. DESIGN AND PARTICIPANTS: This cohort study examined 39,564 hospitalizations of patients aged 18 or older with COVID-19 who received inpatient care between March 13, 2020, and February 28, 2022...
April 8, 2024: Journal of General Internal Medicine
#25
JOURNAL ARTICLE
Adrian F Hernandez, Jacob A Udell, W Schuyler Jones, Stefan D Anker, Mark C Petrie, Josephine Harrington, Michaela Mattheus, Svenja Seide, Isabella Zwiener, Offer Amir, M Cecilia Bahit, Johann Bauersachs, Antoni Bayes-Genis, Yundai Chen, Vijay K Chopra, Gemma Figtree, Junbo Ge, Shaun Goodman, Nina Gotcheva, Shinya Goto, Tomasz Gasior, Waheed Jamal, James L Januzzi, Myung Ho Jeong, Yuri Lopatin, Renato D Lopes, Béla Merkely, Puja B Parikh, Alexander Parkhomenko, Piotr Ponikowski, Xavier Rossello, Morten Schou, Dragan Simic, Philippe Gabriel Steg, Joanna Szachniewicz, Peter van der Meer, Dragos Vinereanu, Shelley Zieroth, Martina Brueckmann, Mikhail Sumin, Deepak L Bhatt, Javed Butler
BACKGROUND: Empagliflozin reduces the risk of heart failure events in patients with type 2 diabetes at high cardiovascular risk, chronic kidney disease, and in those with prevalent heart failure irrespective of ejection fraction. While EMPACT-MI showed empagliflozin does not reduce the risk of the composite of hospitalization of heart failure and all-cause mortality, the impact of empagliflozin on first and recurrent heart failure events in patients after myocardial infarction is unknown...
April 6, 2024: Circulation
#26
Yasuhiro Suzuki, Akira Kuriyama
INTRODUCTION AND IMPORTANCE: Infections of inferior vena cava (IVC) filters are rare. The authors present a case of IVC filter infection following concurrent emphysematous urinary tract infections that was finally treated with prolonged suppressive antibiotic therapy (PSAT). CASE PRESENTATION: A 68-year-old man with pemphigoid and type 2 diabetes mellitus, who had undergone IVC filter placement, was transferred with decreased consciousness, respiratory failure, and hypotension...
April 2024: Annals of Medicine and Surgery
#27
JOURNAL ARTICLE
Abeera Ahmed, Ahmed Mushtaq, Irfan Ali Mirza, Fatima Sana, Syed Rehan Asghar Naqvi
OBJECTIVE: To develop an effective antimicrobial strategy for the management of chronic osteomyelitis. STUDY DESIGN: Observational study. Place and Duration of the Study: Departments of Microbiology and Orthopaedics, Combined Military Hospital Malir, Karachi, Pakistan, from January 2021 to February 2022. METHODOLOGY: Bone biopsies of 45 enrolled participants were taken for microbiological evaluation. Intravenous antibiotic therapy was begun as per empirical therapy based on the local antibiogram and antibiotic policy...
April 2024: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
#28
JOURNAL ARTICLE
Ana Lopez-de-Andres, Rodrigo Jimenez-Garcia, Marta Lopez-Herranz, José Javier Zamorano-Leon, David Carabantes-Alarcon, Valentin Hernandez-Barrera, Javier de Miguel-Diez, Francisco Carricondo, Barbara Romero-Gomez, Natividad Cuadrado-Corrales
INTRODUCTION: To assess time trends in incidence, clinical characteristics, complications, and hospital outcomes among patients with type 1 diabetes (T1D), with type 2 diabetes (T2D), and patients without diabetes who underwent kidney transplant (KT); to identify variables associated with in-hospital mortality (IHM); and to determine the impact of the COVID-19 pandemic. RESEARCH DESIGN AND METHODS: We used a nationwide discharge database to select KT recipients admitted to Spanish hospitals from 2016 to 2020...
April 3, 2024: BMJ Open Diabetes Research & Care
#29
RANDOMIZED CONTROLLED TRIAL
Zachary L Cox, Sean P Collins, Gabriel A Hernandez, A Thomas McRae, Beth T Davidson, Kirkwood Adams, Mark Aaron, Luke Cunningham, Cathy A Jenkins, Christopher J Lindsell, Frank E Harrell, Christina Kampe, Karen F Miller, William B Stubblefield, JoAnn Lindenfeld
BACKGROUND: The primary goals during acute heart failure (AHF) hospitalization are decongestion and guideline-directed medical therapy (GDMT) optimization. Unlike diuretics or other GDMT, early dapagliflozin initiation could achieve both AHF goals. OBJECTIVES: The authors aimed to assess the diuretic efficacy and safety of early dapagliflozin initiation in AHF. METHODS: In a multicenter, open-label study, 240 patients were randomized within 24 hours of hospital presentation for hypervolemic AHF to dapagliflozin 10 mg once daily or structured usual care with protocolized diuretic titration until day 5 or hospital discharge...
April 9, 2024: Journal of the American College of Cardiology
#30
JOURNAL ARTICLE
Juyoung Park, Gabriella Engstrom, Joseph G Ouslander
PURPOSE: The current study compared prevalence of opioid or benzodiazepine (BZD) prescription and co-prescription of opioids and BZD at discharge and return to a community hospital within 30 days, as well as identified clinical characteristics associated with hospital return in patients aged ≥75 years. METHOD: A secondary analysis of a database created during implementation of the Safe Transitions for At Risk Patients program at a 400-bed community teaching hospital in south Florida was conducted...
April 2024: Journal of Gerontological Nursing
#31
JOURNAL ARTICLE
A G Bedada, M J Mpapho, S G Hamda
BACKGROUND: Documentation on the spectrum, comorbidities, profile, and outcomes of adult surgical admissions in Botswana is limited. This information may guide manpower distribution for proposed rotations in the new general surgery training programmes. METHODS: The medical records of adult surgical admissions for a period of one year (August 2017 - July 2018) were reviewed retrospectively. Demographics, types of admissions, dates of admission and discharge, and known comorbidities were captured and the outcomes were analysed...
March 2024: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
#32
JOURNAL ARTICLE
Swati Lambor, Kevin Mathew Varughese, Archan Naik, Dheeraj V Lambor, Markandeya Tiwari, Carnegie J A De Sa
Diagnosis of maxillary sinus pathologies is challenging. Herewith we describe the clinicopathological features in isolated maxillary sinus lesions in tertiary care hospital in Goa, India. The retrospective study included patients treated between 2017 and 2022, of all age groups and gender, who underwent either a biopsy or surgery, providing a histopathological diagnosis. Of the 117 pathologies, 88 (75.2%) were non-neoplastic. The overall frequency of pathologies were polyp in 40.2%, fungal lesions (18.8%), malignancy (13...
April 2024: Indian Journal of Otolaryngology and Head and Neck Surgery
#33
JOURNAL ARTICLE
John Nathan Freeman, Callie Giroux, Timothy King, Christina Marbrey, Matthew Maready, Simeen Pasha, Justin Davis
OBJECTIVES: Our objectives were to characterize variations from standardized, evidence-based guidelines in the management of pediatric patients with diabetic ketoacidosis (DKA) based on initial presentation to a tertiary pediatric emergency department (PED) versus a community emergency department (OSH) and compare clinical outcomes. METHODS: We conducted a retrospective study on children 18 years and younger with DKA who presented to an OSH or PED over a 3-year period...
April 2, 2024: Pediatric Emergency Care
#34
JOURNAL ARTICLE
Rizwan Suliankatchi Abdulkader, Manickam Ponnaiah, Tarun Bhatnagar, Devika S, Amanda G A Rozario, Gayathri K, Malu Mohan, Michaelraj E, Divya Saravanakumar, Aditya Moorthy, Amit Kumar Tyagi, Bhagirathsinh D Parmar, K Devaraja, Gaurav Medikeri, Jutika Ojah, Kajal Srivastava, Karthikeyan K, Nandini Das, Niharika B, Parul Sharma, Pradipta Kumar Parida, Prasanna Kumar Saravanam, Praveen Kulkarni, Priya S, Pushpa Patil S, Rahul Kumar Bagla, Ramesh D, Renuka S Melkundi, Satish S Satpute, Seetharaman Narayanan, Shubhashri Jahagirdar, Simmi Dube, Sunil Kumar Panigrahi, Surendra Babu D, Vaibhav Saini, Rita Singh Saxena, Abhinav Srivastava, Achyut Chandra Baishya, Ajai Garg, Amit Kumar Mishra, Anjan Jyoti Talukdar, Ankita Kankaria, Arathi Karat, Arul Sundaresh Kumar, Ashi Chug, Ashok Vankundre, Balakrishnan Ramaswamy, Bharathi Mb, Bhargav R Jadav, Muthuswamy Dhiwakar, Girija Ghate, Hardik V Shah, Ipsita Saha, Kavya Sivapuram, Krupal J Joshi, Mahendra Singh, Mukesh Chand Bairwa, Divya K, Karthikeyan K, Muthurajesh E, Navneh Samagh, Nethra Dinakaran, Nikhil Gupta, Nitin Gupta, Nitin M Nagarkar, Nitin Solanki, Prasan Kumar Panda, Prithvi Bachalli, Raghunath Shanbag, Rajashri Patil, Rajesh Kumar A, Rakesh Narayan Patil, Ramanikanth Thookkanaickenpalayam Vijayaraghavan, Ramesh Hanumantappa, Rathinavel A, Saleel Kumar Mandal, Sanjay Pandharinath Kishve, Sara Varghese Thomas, Saurav Sarkar, Shalini Thakur, Siddaram Patil, Somu Lakshmanan, Srinivas D Rao, Sumathi V, Tulasi Nayak, Umesh R Dixit, Unnikrishnan B, Varsha Backiavathy, Vijendra Shenoy, Vinay Kumar Hallur, Aparna Bhatnagar, Manoj V Murhekar
In India, the incidence of mucormycosis reached high levels during 2021-2022, coinciding with the COVID-19 pandemic. In response to this, we established a multicentric ambispective cohort of patients hospitalised with mucormycosis across India. In this paper, we report their baseline profile, clinical characteristics and outcomes at discharge. Patients hospitalized for mucormycosis during March-July 2021 were included. Mucormycosis was diagnosed based on mycological confirmation on direct microscopy (KOH/Calcofluor white stain), culture, histopathology, or supportive evidence from endoscopy or imaging...
2024: Mycology
#35
JOURNAL ARTICLE
Sunil Sharma, Robert Stansbury, Priyanka Srinivasan, Edward Rojas, Stuart F Quan, Kassandra Olgers, Scott Knollinger, Calvin Seol, Malleri Hardison, Jesse Thompson, Nickolas Hansen, Wen Sijin
STUDY OBJECTIVES: Obstructive sleep apnea (OSA) is a highly prevalent, yet under-diagnosed condition. Due to its adverse impact on risk for cardiopulmonary disorders, there is interest in pro-active screening of OSA in hospitalized patients. We studied the long-term outcome of such screened patients who were initiated on positive airway pressure (PAP) therapy. METHODS: Hospitalized patients who screened positive for OSA and were confirmed with post-discharge polysomnography (PSG) were dichotomized by PAP adherence and followed for a period of 12 months to evaluate for the composite endpoint of hospital readmissions and emergency room (ED) visits for cardiopulmonary reasons...
April 1, 2024: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
#36
JOURNAL ARTICLE
Keith Sweitzer, Cody Fowler, James Butterfield, Adam Visca, Danielle Mayorga-Young, Julia Tomtschik, Raquel Arias-Camison, Derek Bell
BACKGROUND: The use of left ventricular assist devices (LVADs) for patients with end-stage cardiac failure awaiting heart transplantation has become increasingly common. However, ventricular assist device-related infections remain a major problem complicating their long-term use. Retrospective review has previously shown a decrease in lifetime return to operating room (RTOR) with no change in 90-day complications when a muscle or omental flap is used for coverage after washout for infection...
April 1, 2024: Annals of Plastic Surgery
#37
JOURNAL ARTICLE
Christopher Zammitti, Mayra Tisminetzky, Jordy Mehawej, Hawa O Abu, Ruben Miozzo, Joel M Gore, Darleen Lessard, Benita A Bamgbade, Jorge Yarzebski, Jerry H Gurwitz, Robert J Goldberg
BACKGROUND: Multiple chronic conditions (MCCs) are common in patients hospitalized with acute myocardial infarction (AMI). We examined the association of 12 MCCs with the risk of a 30-day hospital readmission and/or dying within one year among those discharged from the hospital after an AMI. We also examined the five most prevalent pairs of chronic conditions in this population and their association with the principal study endpoints. METHODS: The study population consisted of 3,294 adults hospitalized with a confirmed AMI at the three major medical centers in central Massachusetts on an approximate biennial basis between 2005 and 2015...
2024: J Multimorb Comorb
#38
JOURNAL ARTICLE
Eleanor K Shenton, Amanda G Carter, Laura Gabriel, Valerie Slavin
PROBLEM: Gestational Diabetes Mellitus (GDM) is a complication of pregnancy which may exclude women from midwife-led models of care. BACKGROUND: There is a paucity of research evaluating the safety and feasibility of continuity of midwifery care (CoMC) for women with GDM. AIM: To investigate the impact of CoMC on maternal and neonatal outcomes, for otherwise low-risk women with GDM. METHODS: This exploratory cross-sectional study observed maternal and neonatal outcomes including onset of labour, augmentation, labour analgesia, mode of birth, perineal trauma, gestation at birth, shoulder dystocia, infant birth weight, neonatal feeding at discharge...
March 27, 2024: Women and Birth
#39
JOURNAL ARTICLE
Elizabeth Miles, Melissa McKnight, Claire C Schmitz, Chelsea R McElroy, Jana L Wardian, Valerie Shostrom, Preethi Polavarapu
BACKGROUND: Insulin, a high-risk medication, is prone to prescribing errors. Patients with diabetes experience higher hospitalization rates and extended hospital stays. Prescription errors, such as missing orders, inappropriate insulin type, missing instructions, and lack of appropriate intensification of insulin regimens are common issues. This project explored the use of system-based interventions and educational tools to minimize errors and improve the quality of insulin discharge regimens...
March 28, 2024: Journal of Diabetes Science and Technology
#40
Moayad S Almusaylim, Mohammed S Foula, Jawad F Al Amin, Mohammad A Al-Abbad, Mustafa A Alsaleh
Appendicitis, an inflammation of the vermiform appendix, is one of the most common causes of acute abdomen and one of the most frequent indications for emergency abdominal surgery worldwide. Any person older than 65 years old is considered elderly. The elderly population constitutes only 5-10% of total appendicitis cases. The symptoms depend on the location of the appendix. Generally, lower abdominal pain and anorexia are known to be the most common symptoms of appendicitis. Although young adults have a higher prevalence of appendicitis, the elderly have a higher complication rate, 37...
February 2024: Curēus
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