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https://www.readbyqxmd.com/read/30517505/-effect-of-oxytocin-on-the-levels-of-malondialdehyde-nitric-oxide-and-s100b-protein-in-newborns
#1
Dante Condori-Merma, Oscar Moreno-Loaiza, Azael Paz-Aliaga, José Barrionuevo-Rodríguez
OBJECTIVES: To assess the effects of the administration of oxytocin during labor management on the levels of malondialdehyde (MDA), nitric oxide (NO), and S100B protein in newborns. MATERIALS AND METHODS: We selected 80 term pregnant women without obstetric and fetal pathology, forming two groups: pregnant women with normal delivery and pregnant women conducted with oxytocin. Blood was collected immediately after delivery from the umbilical cord vein to measure MDA, ON and from the artery for protein S100B...
July 2018: Revista Peruana de Medicina Experimental y Salud Pública
https://www.readbyqxmd.com/read/30511800/circulating-tumor-cells-in-the-pulmonary-vein-increase-significantly-after-lobectomy-a-prospective-observational-study
#2
Xinchun Duan, Yujie Zhu, Yong Cui, Zhenrong Yang, Shijie Zhou, Yi Han, Daping Yu, Ning Xiao, Xiaoqing Cao, Yunsong Li, Shuku Liu, Zitong Wang, Wen Zhang, Lin Feng, Kaitai Zhang, Jianzhong Shou, Zhidong Liu, Shaofa Xu
BACKGROUND: It has been reported that there are more circulating tumor cells (CTCs) in the pulmonary vein (PV) than in the peripheral blood; however, it is unclear whether the CTC count changes in the PV after resection of a lung lobe. METHODS: Thirty-three lung cancer patients were recruited for the study, including 17 who underwent lobectomy via video-assisted thoracoscopic surgery and 16 via open thoracotomy. Sixty-six blood specimens were sampled from the PV before the PV was interrupted and after lobectomy...
December 4, 2018: Thoracic Cancer
https://www.readbyqxmd.com/read/30510375/development-of-a-novel-rat-model-of-heterogeneous-hepatic-injury-by-injection-with-colchicine-via-the-splenic-vein
#3
Yan-Yan Zhang, Chao-Xu Zhang, Yu Li, Xuan Jiang, Yong-Fang Wang, Yang Sun, Jun Wang, Wan-Ying Ji, Yi Liu
AIM: To develop a novel rat model of heterogeneous hepatic injury. METHODS: Seventy male Sprague-Dawley rats were randomly divided into a control group ( n = 10) and a colchicine group ( n = 60). A 0.25% colchicine solution (0.4 mL/kg) was injected via the splenic vein in the colchicine group to develop a rat model of heterogeneous hepatic injury. An equal volume of normal saline was injected via the splenic vein in the control group. At days 3, 7, and 14 and weeks 4, 8, and 12 after the operation, at least seven rats of the colchicine group were selected randomly for magnetic resonance imaging (MRI) examinations, and then they were euthanized...
November 28, 2018: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/30508395/application-of-real-time-contrast-enhanced-ultrasound-in-differential-diagnosis-of-liver-malignancies
#4
Hongling Li, Jin Li
OBJECTIVE: To evaluate the value of real time contrast-enhanced ultrasound in differential diagnosis of malignant liver tumors. METHODS: 60 patients pathologically diagnosed with liver cancer from May 2016 to May 2017 were selected as the objects. All patients received ultrasonic diagnosis followed by the observation on dynamic contrast enhancement of the image and the analysis on perfusion characteristics and difference in contrast-enhanced ultrasound results in patients with different types of liver cancer...
December 3, 2018: Canadian Journal of Physiology and Pharmacology
https://www.readbyqxmd.com/read/30508168/utility-of-cement-augmentation-via-percutaneous-fenestrated-pedicle-screws-for-stabilization-of-cancer-related-spinal-instability
#5
Ori Barzilai, Lily McLaughlin, Eric Lis, Anne S Reiner, Mark H Bilsky, Ilya Laufer
BACKGROUND: Cancer patients experience pathological fractures and the typical poor bone quality frequently complicates stabilization. Methods for overcoming screw failure include utilization of fenestrated screws that permit the injection of bone cement into the vertebral body to augment fixation. OBJECTIVE: To evaluate the safety and efficacy of cement augmentation via fenestrated screws. METHODS: A retrospective chart review of patients with neoplastic spinal instability who underwent percutaneous instrumented stabilization with cement augmentation using fenestrated pedicle screws...
December 3, 2018: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/30501987/can-post-hoc-video-review-of-robotic-pancreaticoduodenectomy-predict-portal-superior-mesenteric-vein-margin-status-in-pancreatic-adenocarcinoma
#6
Jae P Jung, Mazen S Zenati, Ahmad Hamad, Melissa E Hogg, Richard L Simmons, Amer H Zureikat, Herbert J Zeh, Brian A Boone
BACKGROUND: Achieving margin negative resection is a significant determinant of outcome in pancreatic adenocarcinoma (PDA). However, because of the fibrotic nature of PDA, it can be difficult to discriminate fibrosis from active disease intra-operatively. We sought to determine if post-hoc video review of robotic pancreatico-duodenectomy (RPD) could predict the portal/superior mesenteric vein (PV/SMV) margin status on final pathology. METHODS: Experienced pancreatic surgeons, blinded to patient and operative variables, reviewed the PV/SMV margin for available RPD videos of consecutive PDA patients from 9/2012 through 6/2017...
November 27, 2018: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/30501116/the-anti-angiogenic-activity-of-a-cystatin-f-homologue-from-the-buccal-glands-of-lampetra-morii
#7
Mingru Zhu, Bowen Li, Jihong Wang, Rong Xiao
Cystatins are a family of cysteine protease inhibitors which are associated with a variety of physiological and pathological processes in vivo. In the present study, the cDNA sequence of a cystatin F homologue called Lm-cystatin F was cloned from the buccal glands of Lampetra morii . Although Lm-cystatin F shares a lower homology with cystatin superfamily members, it is also composed of a signal peptide and three highly conserved motifs, including the G in the N-terminal, QXVXG, as well as the PW in the C-terminal of the sequence...
November 29, 2018: Marine Drugs
https://www.readbyqxmd.com/read/30500288/data-set-for-the-reporting-of-ear-and-temporal-bone-tumors-explanations-and-recommendations-of-the-guidelines-from-the-international-collaboration-on-cancer-reporting
#8
Ruta Gupta, Ann Sandison, Bruce M Wenig, Lester D R Thompson
The International Collaboration on Cancer Reporting (ICCR) was established to internationally unify and standardize the pathologic reporting of cancers based on collected evidence, as well as to allow systematic multi-institutional intercountry data collection to guide cancer care in the future. Such collaborative efforts are particularly essential for developing an evidence base for rare neoplasms, or those with marked geographic variation in incidence, such as the tumors of the ear and the temporal bone. The ear and the temporal bone, including the external auditory canal and the middle and inner ear, with the closely associated facial nerve, internal carotid artery, and internal jugular vein, is one of the most complex anatomic structures in the head and neck...
November 30, 2018: Archives of Pathology & Laboratory Medicine
https://www.readbyqxmd.com/read/30496564/awake-transcortical-approach-resection-of-dominant-posterior-cingulate-gyrus-glioma-2-dimensional-operative-video
#9
N U Farrukh Hameed, Bin Wu, Fangyuan Gong, Jie Zhang, Hong Chen, Jinsong Wu
Two techniques, the translongitudinal cerebral fissure and transfrontal cortical approach, can be employed to resect posterior cingulate gyrus tumors. We demonstrate the transcortical technique comprising of multimodal imaging guidance and awake brain mapping which enabled maximum safe resection of dominant cingulate gyrus glioma. The patient, a 49-yr-old female, came to clinic after experiencing headache for a month. Initial magnetic resonance imaging (MRI) scans revealed a nonenhancing lesion of the left posterior cingulate gyrus...
November 28, 2018: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/30485211/factors-associated-with-venous-thromboembolic-events-following-icu-admission-in-patients-undergoing-spinal-surgery-an-analysis-of-1269-consecutive-patients
#10
(no author information available yet)
OBJECTIVEVenous thromboembolic events (VTEs) are a common cause of morbidity and mortality after spine surgery. Patients admitted to the intensive care unit (ICU) following spine surgery exhibit high-risk clinical characteristics.METHODSThe authors retrospectively analyzed 1269 ICU patients who had undergone spine surgery between January 1, 2009, and May 31, 2015. Relevant demographic, procedural, and outcome variables were collected.RESULTSPatients admitted to the ICU postoperatively had a postoperative VTE rate of 10...
October 1, 2018: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/30481779/galangin-alleviates-liver-ischemia-reperfusion-injury-in-a-rat-model-by-mediating-the-pi3k-akt-pathway
#11
Yang Li, Liquan Tong, Jingyan Zhang, Yafeng Zhang, Feng Zhang
BACKGROUND/AIMS: Liver ischemia-reperfusion (I/R) injury is a pathological process that often occurs during liver and trauma surgery. There are numerous causes of liver I/R injury, but the mechanism is unknown. Galangin (GA) is a flavonoid, a polyphenolic compound widely distributed in medicinal herbs that has anti-inflammatory, antioxidant, and antitumor activity. This study evaluated the protective effect of GA on hepatic I/R injury. METHODS: An I/R model was created in male Wistar rats by clamping the hepatoportal vein, hepatic artery and hepatic duct for 30 min followed by reperfusion for 2 h...
November 27, 2018: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/30475339/30-and-90-day-unplanned-readmission-rates-causes-and-risk-factors-after-cervical-fusion-a-single-institution-analysis
#12
Omar Zaki, Nikhil Jain, Elizabeth Yu, Safdar N Khan
STUDY DESIGN: Retrospective cohort study OBJECTIVE.: To study 30- and 90-day readmission rates, causes, and risk factors after anterior cervical discectomy and fusion (ACDF) and posterior cervical fusion (PCF). SUMMARY OF BACKGROUND DATA: Existing data on readmission after cervical fusion is majorly derived from national databases. Given their inherent limitations in accuracy, follow-up available and missing data, we intend to add to literature from our institutional analysis...
November 20, 2018: Spine
https://www.readbyqxmd.com/read/30473985/microsurgical-decompression-of-trigeminal-neuralgia-caused-by-simultaneous-double-arterial-sca-and-aica-and-petrosal-vein-complex-compression
#13
Domagoj Gajski, Alicia R Dennis, Kenan I Arnautović
Trigeminal neuralgia is a chronic pain disorder affecting the face. In approximately 80% of cases, it is most commonly caused, when the root entry zone (REZ) of the trigeminal nerve is compressed by the superior cerebellar artery (SCA). The etiology of the remaining 20% of cases is distributed among venous, arteriovenous malformations, posterior fossa tumors, multiple sclerosis plaque compressions, and other pathologies. Combinations of those compressive factors are very rare. 1 2 3 4 Herein, we present a video clip of microvascular decompression (MVD) in a 73-year-old female, who has failed conservative treatment with 6 medications over 10 years...
December 2018: Journal of Neurological Surgery. Part B, Skull Base
https://www.readbyqxmd.com/read/30473898/unusual-presentation-of-follicular-dendritic-cell-sarcoma-as-a-cystic-neck-swelling
#14
G Chidananda-Murthy, P Babu, J Chandran, G Raja
Follicular dendritic cell sarcoma is a very rare neoplasm that most commonly involves cervical lymph nodes and usually presents as a solid mass. Presentation as a cystic neck mass is very rare. Radiological studies and aspiration cytology are often unreliable, and diagnosis is usually made after thorough clinical and pathological examination along with immunohistochemical analysis. In this article, we report a case of a 42-year-old man who presented with right-sided neck swelling of a 2-month duration. Contrast-enhanced CT showed a cystic lesion in the right side of the neck inferomedial to parotid gland located between medial border of sternocleidomastoid muscle and internal jugular vein...
2018: Case Reports in Oncological Medicine
https://www.readbyqxmd.com/read/30472920/current-practice-in-treating-chronic-venous-disease-by-canadian-vascular-surgeons
#15
Gary K Yang, Jerry C Chen
OBJECTIVE: To evaluate the practice patterns and interests of vascular surgeons in Canada in the treatment of chronic venous disorder. METHODS: A web-based 19-question survey was sent to 155 active members of the Canadian Society for Vascular Surgery. Questions assessed training background, interest in venous disease, practice site, venous treatments offered, and obstacles to therapy. RESULTS: A total of 64 responses (41%) were acquired. Respondents were roughly equal from academic (55%) and community (45%) sites with an even distribution of years in practice...
November 25, 2018: Phlebology
https://www.readbyqxmd.com/read/30472075/the-potent-small-molecule-integrin-antagonist-thr-687-is-a-promising-next-generation-therapy-for-retinal-vascular-disorders
#16
Tjing-Tjing Hu, Marc Vanhove, Michaël Porcu, Inge Van Hove, Tine Van Bergen, Bart Jonckx Bart, Philippe Barbeaux, Elke Vermassen, Jean H M Feyen
Integrins are associated with various eye diseases such as diabetic retinopathy (DR) and wet age-related macular degeneration (AMD) and implicated in main pathologic disease hallmarks like neovascularization, inflammation, fibrosis and vascular leakage. Targeting integrins has the potential to attenuate these vision-threatening processes, independent of anti-vascular endothelial growth factor (VEGF) responsiveness. The current investigation characterized THR-687 as a novel pan RGD (arginylglycylaspartic acid) integrin receptor antagonist able to compete for binding with the natural ligand with nanomolar potency (e...
November 22, 2018: Experimental Eye Research
https://www.readbyqxmd.com/read/30470244/surgical-repair-of-partial-anomalous-pulmonary-venous-return-with-intact-atrial-septum-in-a-65-year-old-woman-a-case-report
#17
Narihiro Ishida, Katsuya Shimabukuro, Shojiro Yamaguchi, Etsuji Umeda, Hiroki Ogura, Shohei Mitta, Ryutaro Kimata, Hirofumi Takemura, Kiyoshi Doi
BACKGROUND: Partial anomalous pulmonary venous return is a rare congenital cardiac anomaly that usually involves the right pulmonary vein and an atrial septal defect. Isolated partial anomalous pulmonary venous return with an intact atrial septum is even rarer, and this condition is usually treated surgically in younger patients. We describe isolated partial anomalous pulmonary venous return in a 65-year-old woman who was treated by caval division with pericardial patch baffling through a surgically created atrial septal defect and reconstruction of the superior vena cava using a prosthetic graft...
November 24, 2018: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/30467703/robotic-resection-of-the-uncinate-process-of-the-pancreas
#18
Marcel Autran C Machado, Rodrigo Surjan, Tiago Basseres, Fabio Makdissi
Since the development of the robotic platform, the number of robotic-assisted surgeries has significantly increased. Robotic surgery has gained growing acceptance in recent years, expanding to pancreatic resection. Here, we report a total robotic resection of the uncinate process of the pancreas performed in a patient with a cystic neuroendocrine tumor. To our knowledge, this is the first report of a robotic resection of the uncinate process of the pancreas. A 46-year-old man with no specific medical history was diagnosed with a neuroendocrine tumor after undergoing routine imaging...
November 23, 2018: Journal of Robotic Surgery
https://www.readbyqxmd.com/read/30467306/protective-effects-of-apoptosis-of-kupffer-cells-induced-by-zoledronate-liposomes-following-hepatic-ischemia-reperfusion-injury
#19
Qiao-Hong Zhao, Feng Han, Kun Wu, Jie Zhang, Tian-Fang Xia, Jian Chen, Zhen-Shen Qing, Li-Qun Pang
BACKGROUND The goal of this study was to observe the effect of the apoptosis of Kupffer cells (KCs) selectively induced by zoledronate liposomes following the hepatic ischemia-reperfusion injury (IRI) in the rat liver transplantation model and to explore its mechanisms. MATERIAL AND METHODS The rat liver transplantation model was established using the improved Kamada method. Male Sprague Dawley rats were randomly divided into 3 groups: no liver transplantation or drug treatment (Group A); donor rats were injected with 1 mL normal saline through the tail vein for 3 continuous days before transplantation, and the donor liver was preserved in cold for 2 hours (Group B); donor rats were injected with 1 mL zoledronate liposomes (0...
November 23, 2018: Annals of Transplantation: Quarterly of the Polish Transplantation Society
https://www.readbyqxmd.com/read/30467286/mir-542-5p-attenuates-fibroblast-activation-by-targeting-integrin-%C3%AE-6-in-silica-induced-pulmonary-fibrosis
#20
Jiali Yuan, Ping Li, Honghong Pan, Yan Li, Qi Xu, Tiantian Xu, Xiaoming Ji, Yi Liu, Wenxi Yao, Lei Han, Chunhui Ni
Silicosis is a very serious occupational disease and it features pathological manifestations of inflammatory infiltration, excessive proliferation of fibroblasts and massive depositions of the extracellular matrix in the lungs. Recent studies described the roles of a variety of microRNAs (miRNAs) in fibrotic diseases. Here, we aimed to explore the potential mechanism of miR-542-5p in the activation of lung fibroblasts. To induce a pulmonary fibrosis mouse model, silica suspension and the miR-542-5p agomir were administered to mice by intratracheal instillation and tail vein injection...
November 22, 2018: International Journal of Molecular Sciences
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