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https://www.readbyqxmd.com/read/30117191/pig-tracheal-patchy-xenotransplantation-in-the-dog
#1
Tae-Ki Lee, Jong-Min Kim, Seok Hwa Choi
BACKGROUND: A long-segmental tracheal lesion is difficult to repair by tracheal allotransplantation due to the lack of a well-defined blood supply for blood vessel anastomosis. The donor trachea needs to be revascularized within a well-vascularized soft tissue flap for several months to allow successful trachea allotransplantation. To date, xenotransplantation using the wild-type or genetically modified pig has been widely studied. The object of this study was to evaluate the feasibility of a small-sized (2 × 2 cm) wild-type pig tracheal patchy in a dog tracheal defect model before trying a long-segment tracheal defect model and using a genetically modified pig as a donor in dog xenotransplantation...
August 17, 2018: Xenotransplantation
https://www.readbyqxmd.com/read/30111935/chondrodysplasia-punctata-with-severe-airway-stenosis
#2
Bobbity Deepthi, Viswas Chhapola, Sandeep Kumar Kanwal, Ankita Goel Sharma, Virendra Kumar
Chondrodysplasia punctata (CDP) is a group of skeletal dysplasias characterized primarily by punctate calcifications in cartilage. It is a rare disease with an incidence of 1:100,000 live births. Extensive airway involvement with calcification of tracheal, bronchial, and thyroid cartilage in CDP is an infrequent finding. We aim to report a case of CDP with characteristic radiological features and severe airway involvement.
July 2018: Indian Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/30101671/trachea-engineering-using-a-centrifugation-method-and-mouse-induced-pluripotent-stem-cells
#3
Qiliang Zhou, Xulu Ye, Qingsong Ran, Akihiko Kitahara, Yoshifumi Matsumoto, Masato Moriyama, Yoichi Ajioka, Yasuo Saijo
The outcomes of tracheal transplantation for the treatment of airway stenosis are unsatisfactory. We investigated the feasibility of regeneration of the trachea using a rat decellularized tracheal scaffold and mouse induced pluripotent stem (iPS) cells for in vivo transplantation. The rat trachea was first decellularized using a detergent-enzymatic treatment method. We successfully established a centrifugation method that can transplant cells onto the luminal surface of the decellularized rat tracheal scaffold circumferentially...
August 13, 2018: Tissue Engineering. Part C, Methods
https://www.readbyqxmd.com/read/30099581/pitfalls-in-the-management-of-congenital-tracheal-stenosis-is-conservative-management-feasible
#4
Yoshiko Usui, Shigeru Ono, Katsuhisa Baba, Yuki Tsuji
PURPOSE: Congenital tracheal stenosis (CTS) is rare and challenging. Complete tracheal rings cause a wide spectrum of airway-obstructing lesions and varying degrees of respiratory distress. Although surgical reconstruction is the primary option for symptomatic CTS, sometimes an appropriate management strategy may be difficult due to other anomalies. We aimed to identify pitfalls in the management of CTS. METHODS: We retrospectively reviewed the records of patients with CTS during the last 10 years in our institution...
August 11, 2018: Pediatric Surgery International
https://www.readbyqxmd.com/read/30076020/post-treatment-sequelae-and-management-of-primary-laryngeal-nk-t-cell-lymphoma-a-case-report
#5
Joseph B Meleca, Andrea Hanick, Eric Lamarre, Paul C Bryson
OUTCOME OBJECTIVES: METHODS: Case Report, April 2016. RESULTS: A 27-year-old female presented with a three-week history of flu-like symptoms including sore throat, myalgia and insidious nasal congestion. Her hospital course was complicated by pancytopenia, extensive GI bleed of unknown origin and fever. Radiographic studies revealed multifocal centrilobular ground-glass lung nodules, splenomegaly, frontal and paranasal sinus opacification and mucosal thickening and inflammatory process of false and true vocal cords with concentric multi-level narrowing...
July 25, 2018: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/30076019/office-based-retrograde-transtracheal-application-of-mitomycin-c
#6
Valeria Silva Merea, Paul C Bryson
OBJECTIVES: The utility of topical mitomycin C (MMC) as an adjuvant treatment in the management of laryngeal and tracheal stenosis has been studied; however, the ideal timing of MMC application has not been fully elucidated. There is a paucity of studies evaluating the timing of MMC application after surgical airway intervention for stenosis. The purpose of this study is to describe a novel technique for MMC application that allows for delayed application in the unsedated, office-based setting, approximately one week following endoscopic airway dilation...
July 26, 2018: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/30057829/the-clinical-cases-of-geleophysic-dysplasia-one-gene-different-phenotypes
#7
Evgenia Globa, Nataliya Zelinska, Andrew Dauber
Background: Geleophysic dysplasia is a rare multisystem disorder that principally affects the bones, joints, heart, and skin. This condition is inherited either in an autosomal dominant pattern due to FBN1 mutations or in an autosomal recessive pattern due to ADAMTSL2 mutations. Two patients with unaffected parents from unrelated families presented to their endocrinologist with severe short stature, resistant to growth hormone treatment. Routine endocrine tests did not reveal an underlying etiology...
2018: Case Reports in Endocrinology
https://www.readbyqxmd.com/read/30054082/use-of-silicone-tubes-in-the-management-of-complex-airway-problems
#8
REVIEW
Joel D Cooper
Silicone airway stents are extremely useful for both temporary or long-term management of upper airway obstruction, especially in the proximal half of the trachea and in the subglottic region. They cannot migrate are well tolerated, relatively easy to manage, durable, and generally cause little or no injury to the underlying airway mucosa. They are particularly important as part of the management of subglottic strictures. For patients with postintubation tracheal or laryngotracheal stenosis they can be used to temporize for periods up to a year or two, until the patients' condition is optimal for proceeding with a resection or reconstruction...
August 2018: Thoracic Surgery Clinics
https://www.readbyqxmd.com/read/30048420/prevalence-and-characteristics-of-tracheal-lesions-observed-in-tracheostomized-patients
#9
Fernando Planells, Dario Villalba, Feld Viviana, Valeria Leiva, Mariana Scrigna, Eduardo Distéfano, Jessica Collins, Ana Rocco, Amelia Matesa, Laura Áreas, Nicolas Golfarini, Gregorio Gil-Rossetti, María P Pini, Marcos Hannun, Sabrina Boni, Sabrina Grimaldi, Paula Pedace, Pablo Díaz-Ballvé, Mauro Andreu, Pablo Buñirigo, Diego Noval
BACKGROUND: Our objective was to describe the prevalence and characteristics of tracheal lesions observed in flexile bronchoscopies of tracheostomized patients, and to determine those factors associated with severe injuries. METHODS: This is an analytical, observational, and transversal study. The flexible bronchoscopies of tracheostomized patients from our database were reviewed to assess their lesions. The tracheal lesions were classified according to their severity; lesions obstructing above 50% of the lumen were interpreted as severe and those obstructing <50% as mild...
July 25, 2018: Journal of Bronchology & Interventional Pulmonology
https://www.readbyqxmd.com/read/30047981/using-middle-finger-length-to-determine-the-internal-diameter-of-uncuffed-tracheal-tubes-in-paediatrics
#10
S Ritchie-McLean, V Ferrier, B Clevenger, M Thomas
The selection of an appropriately-sized tracheal tube is of critical importance in paediatric patients to reduce both the risk of subglottic stenosis from a tracheal tube that is too large, and inadequate ventilation or poor end-tidal gas monitoring from a tracheal tube that is too small. Age formulae are widely used, but known to be unreliable, often resulting in a need to change the tracheal tube. Previous work has shown that the length of the middle finger and the internal diameter can both be used to guide depth of tracheal tube insertion...
July 26, 2018: Anaesthesia
https://www.readbyqxmd.com/read/30023373/surgery-for-intrathoracic-tracheoesophageal-and-bronchoesophageal-fistula
#11
REVIEW
Benoit Jacques Bibas, Paulo Francisco Guerreiro Cardoso, Helio Minamoto, Paulo Manoel Pêgo-Fernandes
Benign tracheoesophageal fistula (TEF) results from an abnormal communication between the posterior wall of the trachea or bronchi and the adjacent anterior wall of the esophagus. It can be acquired or congenital. The onset of the TEF has a negative impact on the patient's health status and quality of life because of swallowing difficulties, recurrent aspiration pneumonia, and severe weight loss. Several acquired conditions may cause TEF. The most frequent is prolonged orotracheal intubation (75% of the cases)...
June 2018: Annals of Translational Medicine
https://www.readbyqxmd.com/read/29997975/application-of-the-montgomery-t-tube-in-subglottic-tracheal-benign-stenosis
#12
Huihui Hu, Jisong Zhang, Fengjie Wu, Enguo Chen
No abstract text is available yet for this article.
May 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29997917/laryngeal-mask-for-airway-management-in-open-tracheal-surgery-a-retrospective-analysis-of-54-cases
#13
Martina Krecmerova, Jan Schutzner, Pavel Michalek, Paul Johnson, Tomas Vymazal
Background: Airway management in tracheal resections presents many challenges. The aim of this retrospective analysis is to report the efficacy and complications associated with the use of the laryngeal mask airway in this procedure. Methods: The charts of 54 consecutive patients operated for tracheal stenosis during the period 2009-2016 were reviewed. This cohort included only resections of the trachea. We evaluated total success rate of laryngeal mask insertion (%), insertion success rate on the first attempt, the quality of intraoperative ventilation through the laryngeal mask, the quality of fibre optic view through the device, incidence of bleeding during the first 24 h, signs of dehiscence of the anastomosis within 48 h and 30-day mortality...
May 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29983755/holmium-laser-for-endoscopic-treatment-of-benign-tracheal-stenosis
#14
D J Verret, Ameya Jategaonkar, Samuel Helman, Sameep Kadakia, Arash Bahrami, Eli Gordin, Yadranko Ducic
Introduction  Laryngotracheal stenosis is a difficult problem with varied etiology and various treatment options. The holmium laser represents another tool for the treatment of benign tracheal stenosis. Objectives  To determine the utility of holmium laser treatment for benign tracheal stenosis with regards to safety and efficacy. Methods  This was a retrospective case study examining patients with benign tracheal stenosis from 1998-2016 who underwent holmium laser treatment. Determining the safety of this procedure was the primary goal, and complications were monitored as a surrogate of safety...
July 2018: International Archives of Otorhinolaryngology
https://www.readbyqxmd.com/read/29978956/-multidisciplinary-approach-on-subglottic-pathology-a-5-year-review
#15
I Miró, C Gutiérrez, R Fonseca, J E Barrios, E Carazo, A Alamar, I Ibáñez, J López, P Ortolá, J J Vila
INTRODUCTION: Pediatric subglottic pathology still represents a challenge when it comes to choosing the right treatment. We present the management of patients followed in our center for this reason during the last 5 years. MATERIAL AND METHODS: Retrospective study of patients followed by glotosubglottic pathology (stenosis, cysts or granulomas) between 2011 and 2016 in a third level hospital. RESULTS: Twenty-seven patients were included in the review...
April 20, 2018: Cirugía Pediátrica: Organo Oficial de la Sociedad Española de Cirugía Pediátrica
https://www.readbyqxmd.com/read/29969925/diagnosis-and-management-of-laryngotracheal-stenosis
#16
Matthew M Smith, Robin T Cotton
Laryngotracheal stenosis comprises a broad spectrum of congenital and acquired conditions that commonly cause pediatric airway obstruction. Although the majority of these conditions were historically managed with endoscopic dilations, the introduction of operative procedures such as laryngotracheoplasty, cricotracheal resection, and slide tracheoplasty changed the treatment paradigm. The gradual evolution of endoscopic technology enabled surgeons to perform certain procedures endoscopically that were previously only able to be performed in an open fashion...
August 2018: Expert Review of Respiratory Medicine
https://www.readbyqxmd.com/read/29961932/anesthetic-management-in-tracheal-dilatation-for-severe-tracheal-stenosis
#17
Kenji Ito, Kai Yamazaki, Takugi Kan, Shuhei Tetsu, Keiichiro Saito, Mitsutomo Kohno, Masayuki Iwazaki, Toshiyasu Suzuki
We report the anesthetic management of a 65-year-old woman with recurrent, severe tracheal stenosis who underwent tracheal dilatation. She had visited the Department of Respiratory Medicine at our hospital for respiratory distress approximately 20 years ago, and had undergone laser ablation under local anesthesia. Because of recurrence and aggravation of respiratory distress, she now presented at the Department of Thoracic Surgery, and was scheduled for surgery. Percutaneous cardiopulmonary support was prepared, and she was sedated with midazolam and dexmedetomidine...
July 20, 2018: Tokai Journal of Experimental and Clinical Medicine
https://www.readbyqxmd.com/read/29953099/-tracheolaryngeal-resection-for-cicatricle-stenosis
#18
V D Parshin, M A Rusakov, V V Parshin, V A Titov, A V Parshin, A V Starostin
AIM: To determine the safest and the most effective surgical treatment of patients with cicatricle stenosis of tracheolaryngeal segment via analysis of different approaches. MATERIAL AND METHODS: For the period 1963-2015 at Petrovsky Russian Research Center for Surgery and Sechenov First Moscow State Medical University 1128 patients with cicatricle tracheal stenosis have been treated. There were 683 men and 445 women. 684 (60.6%) patients were young and the most employable (21-50 years)...
2018: Khirurgiia
https://www.readbyqxmd.com/read/29945809/-osteochondroplastic-tracheobronchopathy-about-three-cases
#19
M Ferreira, H Morel, A Dixmier, F Arbion, S Marchand-Adam
INTRODUCTION: Osteochondroplastic tracheobronchopathy (OCTB) is a rare disorder of unknown cause that affects the tracheobronchial tree. It is characterized by multiple cartilaginous formations or bone nodules projecting into the tracheal or proximal bronchial lumen. It is usually asymptomatic because of the slow progression of the nodules. However, chronic cough, recurrent hemoptysis or recurrent respiratory infections have been reported. OBSERVATIONS: We describe the cases of three patients with symptomatic OCTB: two men and one woman consulting for bronchial infections or pneumonia with sputum difficulties (2 cases) or simply for chronic cough (1 case)...
June 23, 2018: Revue des Maladies Respiratoires
https://www.readbyqxmd.com/read/29941196/-inhalational-anesthesia-maintenance-with-the-janus-facial-mask-for-transcatheter-aortic-valve-replacement-a-case-series
#20
Caetano Nigro Neto, Emerson Domingos da Costa, Francisco José Lucena Bezerra, Mariana Suete Guimarães Ruy, Jose Leonardo Izquierdo Saurith, João Henrique Zucco Viesi
BACKGROUND AND OBJECTIVES: Aortic stenosis is the most common type of heart valve disease. Percutaneous aortic valve replacement has become the alternative for patients considered at high risk for surgery. Controlled mechanical ventilation with tracheal intubation has been the choice for this type of procedure, however the use of noninvasive ventilation in cardiac patients has shown to be beneficial. Janus is a novel full-face mask that allows application of noninvasive ventilation support during anesthesia...
June 22, 2018: Revista Brasileira de Anestesiologia
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