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https://www.readbyqxmd.com/read/30531747/-long-term-oucomes-of-tracheal-transplantation-success-and-unsolved-problems
#1
V D Parshin, A V Lyundup, E A Tarabrin, V V Parshin
AIM: To analyze long-term outcomes of tracheal transplantation. MATERIAL AND METHODS: There were 1128 patients with cicatricial tracheal stenosis who have been operated at the Petrovsky Russian Research Center for Surgery and the Sechenov First Moscow State Medical University for the period 1963-2015. RESULTS: Operations have become safer. Postoperative morbidity and mortality reduced from 41.4% (1963-1980) to 5.6% (2001-2015) and from 21...
2018: Khirurgiia
https://www.readbyqxmd.com/read/30528176/tailored-management-of-airway-abnormalities-in-children-with-congenital-single-functional-lung
#2
Madhavan Ramaswamy, Pilar Anton-Martin, Laura Garcia Martinez, Nagarajan Muthialu
OBJECTIVES: Pediatric patients born with single functional lung can be associated with symptomatic airway abnormalities. Management of such patients is not only technically demanding but is also ethically challenging. This study reports our experience of managing symptomatic airway abnormalities in pediatric patients with congenital single functional lung. METHODS: Observational retrospective cohort study performed at a tertiary children's hospital from January 2001 to September 2017...
October 30, 2018: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/30498269/predictors-of-recurrence-after-surgical-treatment-of-idiopathic-progressive-subglottic-stenosis
#3
I Fiz, J C Koelmel, C Piazza, F Fiz, D Di Dio, Z Bittar, G Peretti, C Sittel
Idiopathic progressive subglottic stenosis is a rare cause of tracheal narrowing. Partial cricotracheal resection and anastomosis can cure idiopathic stenosis, even if some patients may require multiple interventions and experience voice and swallowing deterioration. We investigated risk factors for retreatment and assessed the impact of crico-tracheal resection on functional parameters. We conducted a retrospective multicentric study on 44 female patients (mean age 52.6 ± 13.1 years) affected by idiopathic stenosis and treated by crico-tracheal resection between 2002 and 2016...
October 2018: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/30486575/-effects-of-different-time-of-cryoablation-on-the-proliferation-of-airway-traumatic-granuloma-and-its-mechanism-in-rabbits
#4
B S Xie, L Ye, G P Li, G Y Lin, Y H He, G Y Zheng, G X Lai
Objective: To investigate the effect of different cryoablation time on tracheal traumatic granulation formation and its mechanism. Methods: A total of 32 rabbits were randomly assigned into four groups (A-D). Group A underwent tracheotomy alone. Group B, C and D received intra-tracheal brush rubbing to establish airway granulation model. Group C and D underwent 30 s and 2-minute cryoablation respectively. Tracheal specimens of all groups were collected to examine pathological changes using HE staining. Levels of transforming growth factor beta 1 (TGF-β(1)) and CD34 in tracheal granulation were evaluated using immunohistochemistry (IHC) and real-time quantitative reverse transcription polymerase chain reaction (RT-qCR)...
November 27, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/30481940/-the-clinicopathological-features-and-curative-effect-of-the-bronchoscopic-interventional-therapy-combined-with-radiotherapy-for-the-treatment-of-locally-recurrent-lung-adenoid-cystic-carcinoma
#5
D C Zhu, J H Xu, M H Zhang, H X Zhu, Y Zhang, T Zhang, G R Xu
Objective: To explore the clinical value of endoscopic interventional therapy for locally recurrent primary lung adenoid cystic carcinoma (ACC). Methods: The clinical data of 42 patients with locally recurrent ACC were retrospectively analyzed, and the differences of tracheal and bronchial diameter, airway scoring grade and airway obstruction degree before and after treatment were compared among three treatment methods: bronchoscopic interventional therapy + palliative radiotherapy, interventional therapy alone, and non-interventional therapy...
November 23, 2018: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
https://www.readbyqxmd.com/read/30481123/health-care-costs-and-cost-effectiveness-in-laryngotracheal-stenosis
#6
Linda X Yin, William V Padula, Shekhar Gadkaree, Kevin Motz, Sabrina Rahman, Zachary Predmore, Alexander Gelbard, Alexander T Hillel
OBJECTIVE: Laryngotracheal stenosis (LTS) is resource-intensive disease. The cost-effectiveness of LTS treatments has not been adequately explored. We aimed to conduct a cost-effectiveness analysis comparing open reconstruction (cricotracheal/tracheal resection [CTR/TR]) with endoscopic dilation in the treatment of LTS. STUDY DESIGN: Retrospective cohort. SETTING: Tertiary referral center (2013-2017). SUBJECTS AND METHODS: Thirty-four LTS patients were recruited...
November 27, 2018: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/30479232/-postintubation-tracheal-stenosis
#7
Efsun Gonca Uğur Chousein, Mehmet Akif Özgül
Postintubation tracheal stenosis (PITS) is an iatrogenic complication seen increasingly often as the number of intensive care unit (ICU) bed multiply, the indications for endotracheal intubation expand and disease awareness rises. PITS has a clinical severity spectrum ranging from asymptomatic cases to patients requiring urgent interventional procedures. It should therefore always be considered in the differential diagnosis in patients with a history of intubation who present with the complaint of difficult breathing...
September 2018: Tüberküloz Ve Toraks
https://www.readbyqxmd.com/read/30464519/the-clinical-feasibility-of-flexible-bronchoscopy-interventional-therapy-in-patients-with-central-airway-stenosis-and-respiratory-failure-caused-by-malignancy
#8
Jiwang Wang, Yang Yang, Wangjian Zha, Xiuwei Zhang
Objective: The aim of this study was to investigate the clinical effects and feasibility of using flexible bronchoscopy intervention in cases of malignancy that causes central airway stenosis and respiratory failure. Methods: The clinical data of patients who were admitted to the Department of Respiratory Medicine at the First Affiliated Hospital of Nanjing Medical University and underwent treatment of a malignant tumor with central airway stenosis and respiratory failure by flexible bronchos-copy from February 2010 to May 2013 were analyzed using a retrospective method...
2018: OncoTargets and Therapy
https://www.readbyqxmd.com/read/30454773/tracheostomy-emergencies
#9
REVIEW
Laura J Bontempo, Sara L Manning
Tracheostomy is a common procedure for long-term airway management. Although the overall complication rate is greater than 50%, the incidence of serious complications is low. These serious complications can, however, lead to significant morbidity and mortality and it is incumbent on the emergency provider to be prepared to deal with such tracheostomy-related emergencies. The greatest life threats to the tracheostomy patient are decannulation, obstruction, and hemorrhage. Other important but lower-acuity complications include tracheoesophageal fistula formation, tracheal stenosis, infection, and tracheocutaneous fistula formation...
February 2019: Emergency Medicine Clinics of North America
https://www.readbyqxmd.com/read/30451550/an-omentum-cultured-3d-printed-artificial-trachea-in-vivo-bioreactor
#10
Hae Sang Park, Ji Seung Lee, Harry Jung, Do Yeon Kim, Sang Wook Kim, Md Tipu Sultan, Chan Hum Park
The purpose of this study was to evaluate whether the prior implantation of a 3D-printed polycaprolactone (PCL) artificial trachea in the omentum is beneficial for revascularization of the scaffold and reduces associated complications in the reconstruction of a circumferential tracheal defect. Ten New Zealand rabbits were divided into 2 groups: (1) PCL-OC group (PCL scaffold cultured in omentum for 2 weeks before transplantation) and (2) PCL group. In the PCL-OC group, newly formed connective tissue completely covered the luminal surface of the scaffold with mild inflammation at 2 weeks postoperatively; a minor degree of stenosis was noted at 8 weeks postoperatively...
November 19, 2018: Artificial Cells, Nanomedicine, and Biotechnology
https://www.readbyqxmd.com/read/30449870/-successful-treatment-of-a-patient-with-idiopathic-subglottic-stenosis
#11
Nahoko Shimizu, Yugo Tanaka, Sanae Kuroda, Hayate Nakamura, Gaku Matsumoto, Suguru Mitsui, Shuto Sakai, Kazuhiro Minami, Takeshi Okamoto, Takefumi Doi, Daisuke Hokka, Yoshimasa Maniwa
Idiopathic subglottic stenosis (ISS) is defined as the narrowing of the upper airway without any known cause. A 40-year-old female was referred to our hospital with the complaint of exacerbation of dyspnea causing difficulty in going out. Chest computed tomography (CT) scan and bronchoscopy revealed subglottic tracheal stenosis with a luminal diameter of 5 mm at the narrowest part. Tracheal mucosa of the stenotic lesion was smooth, and the patient had no previous medical history. Subglottic tracheal resection of the stenotic lesion and reconstruction were performed...
November 2018: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/30431441/airway-compression-during-transcatheter-aortic-valve-replacement-via-subclavian-artery-approach-a-case-report
#12
Diana S DeAndrade, Nicholas F Smith, Stephen M McHugh
Transcatheter aortic valve replacement (TAVR) is an alternative to traditional surgery in patients considered to be at high or intermediate risk for open surgical repair of aortic stenosis. Despite its overall safety and efficacy, TAVR is associated with potentially serious complications including major vascular injury. Tracheal compression resulting from vascular pathology has been previously reported; however, airway compromise secondary to vascular injury during TAVR has not been described. We report a case of airway compression and respiratory compromise resulting from injury to the right subclavian artery during TAVR...
November 12, 2018: A&A practice
https://www.readbyqxmd.com/read/30417010/reconstruction-of-ovine-trachea-with-a-biomimetic-composite-biomaterial
#13
Wojciech Ścierski, Grażyna Lisowska, Grzegorz Namysłowski, Maciej Misiołek, Jan Pilch, Elżbieta Menaszek, Radosław Gawlik, Marta Błażewicz
The aim of this study was to evaluate a novel composite material for tracheal reconstruction in an ovine model. A polymer containing various forms of carbon fibers (roving, woven, and nonwoven fabric) impregnated with polysulfone (PSU) was used to create cylindrical tracheal implants, 3 cm in length and 2.5 cm in diameter. Each implant, reinforced with five rings made of PSU-impregnated carbon-fiber roving, had three external layers made of carbon-fiber woven fabric and the inner layer formed of carbon-fiber nonwoven fabric...
2018: BioMed Research International
https://www.readbyqxmd.com/read/30400698/-the-research-progress-of-laryngotracheal-stenosis-in-children
#14
REVIEW
(no author information available yet)
Children's laryngotracheal stenosis is the formation of laryngotracheal scar tissue caused by congenital or acquired factors, resulting in a narrow respiratory tract,which affects breathing. With the development of intensive care,tracheal intubation is widely used in premature infants and critically ill children.Therefore,the incidence of laryngotracheal stenosis in children has increased year by year.Children often need multiple steps of operations, poor surgical tolaerance, seriously affecting the quality of life of the whole family...
November 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/30396407/airway-anomalies
#15
REVIEW
April M Landry, Michael J Rutter
This article reviews congenital anomalies involving the larynx and trachea, including congenital subglottic stenosis, laryngeal webs, laryngeal cleft, and tracheal stenosis. Presenting signs and symptoms, prevailing surgical repair techniques, and postoperative care are discussed.
December 2018: Clinics in Perinatology
https://www.readbyqxmd.com/read/30388721/tracheal-replacement-using-an-in-body-tissue-engineered-collagenous-tube-biotube-with-a-biodegradable-stent-in-a-beagle-model-a-preliminary-report-on-a-new-technique
#16
Shohei Hiwatashi, Yasuhide Nakayama, Satoshi Umeda, Yuichi Takama, Takeshi Terazawa, Hiroomi Okuyama
INTRODUCTION:  Tracheal reconstruction for long-segment stenosis remains challenging. We investigate the usefulness of BIOTUBE, an in-body tissue-engineered collagenous tube with a biodegradable stent, as a novel tracheal scaffold in a beagle model. MATERIALS AND METHODS:  We prepared BIOTUBEs by embedding specially designed molds, including biodegradable stents, into subcutaneous pouches in beagles. After 2 months, the molds were filled with ingrown connective tissues and were harvested to obtain the BIOTUBEs...
November 2, 2018: European Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/30369384/resection-and-reconstruction-of-the-trachea-for-the-treatment-of-upper-tracheal-stenosis-tracheal-versus-non-tracheal-intubation
#17
Feng Li, Jing Liang, Xiaogang Li
Tracheal stenosis may occur secondary to trauma, tumors, infections, and inflammatory and iatrogenic diseases. Patients with tracheal stenosis must be evaluated carefully and require comprehensive preoperative examination, including pulmonary function tests and radiographic studies. Two male patients (one 18 years of age and the other 46 years of age) with tracheal stenosis were scheduled for tracheal resection and reconstruction. They were given different modes of anesthesia (with and without intubation). Fiberoptic intubation was selected in the 18-year patient, and non-intubation was selected in 46-year patient...
November 2018: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/30369056/indications-of-transnasal-humidified-rapid-insufflation-ventilatory-exchange-thrive-in-laryngoscopy-a-prospective-study-of-19-cases
#18
L Maupeu, T Raguin, M Hengen, P Diemunsch, P Schultz
In suspension microlaryngoscopy, the endotracheal tube, which hampers the vision of the subglottic plane, may disturb the surgery. Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) provides effective aventilatory mass flow under deep sedation and seems an interesting approach to operate without endotracheal tube. The objective is to evaluate the indications, the technique and the failures of THRIVE in laryngeal surgery. This prospective study included 19 patients over the age of 18, that overwent laryngeal surgery under laryngosuspension...
October 28, 2018: Clinical Otolaryngology
https://www.readbyqxmd.com/read/30368394/employing-bioabsorbable-grafts-in-two-stage-laryngotracheal-reconstruction-of-pediatric-patient-with-severe-subglottic-stenosis-and-history-of-airway-surgery
#19
Elliot Le, Lenhanh Tran
A 16-month old female was referred to our practice for laryngotracheal reconstruction (LTR) for acquired subglottic stenosis (SGS) diagnosed at 4 weeks of age due to prolonged intubation. She has a history of open thoracic repair of congenital tracheoesophageal fistula that was complicated by a pneumothorax and phrenic nerve paralysis. We performed a variation of an anterior and posterior cricoid split LTR with tracheal stenting in order to avoid risks of pulmonary morbidity from costochondral cartilage harvesting...
December 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/30357596/metallic-stent-insertion-and-removal-for-post-tracheotomy-and-post-intubation-tracheal-stenosis
#20
Yonghua Bi, Zepeng Yu, Jianzhuang Ren, Xinwei Han, Gang Wu
PURPOSE: To study the safety and effectiveness of fluoroscopic insertion and removal of self-expandable metallic airway stent for post-tracheotomy tracheal stenosis (PTTS) and post-intubation tracheal stenosis (PITS). METHODS: We conducted a retrospective analysis of 32 patients who underwent fluoroscopic stenting from September 2011 to March 2017. The patients ranged in age from 12 to 69 years. Thirty-eight airway stents were implanted, 35 covered stents and three bare stents...
October 24, 2018: La Radiologia Medica
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